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Comparative Biochemistry and Physiology, Part A, ISSN 1095-6433, 11/2012, Volume 163, Issue 3-4, pp. 231 - 245
Journal Article
JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 07/2008, Volume 118, Issue 7, pp. 2609 - 2619
Although some cancers are initially sensitive to EGFR tyrosine kinase inhibitors (TKIs), resistance invariably develops. We investigated mechanisms of acquired... 
BREAST-CANCER | GENE-MUTATIONS | MEDICINE, RESEARCH & EXPERIMENTAL | LUNG-CANCER | GROWTH-FACTOR-RECEPTOR | T790M MUTATIONS | IN-VIVO | TUMOR-CELLS | ANTITUMOR-ACTIVITY | GEFITINIB SENSITIVITY | ERLOTINIB | Insulin-Like Growth Factor Binding Protein 3 - genetics | Receptor, IGF Type 1 - metabolism | Insulin-Like Growth Factor I - pharmacology | Receptor, ErbB-3 - metabolism | Receptor, IGF Type 1 - antagonists & inhibitors | Gene Expression - drug effects | Carcinoma, Squamous Cell - pathology | Humans | Drug Resistance, Neoplasm | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Insulin-Like Growth Factor Binding Protein 3 - metabolism | Insulin Receptor Substrate Proteins | Insulin-Like Growth Factor Binding Protein 4 - metabolism | Female | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Cell Survival - drug effects | Insulin-Like Growth Factor Binding Proteins - genetics | Insulin-Like Growth Factor Binding Protein 4 - genetics | Insulin-Like Growth Factor II - metabolism | Insulin-Like Growth Factor Binding Proteins - metabolism | Xenograft Model Antitumor Assays | Animals | Carcinoma, Squamous Cell - drug therapy | Mice, Nude | Protein Kinase Inhibitors - therapeutic use | Quinazolines - therapeutic use | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Mice | Protein Kinase Inhibitors - pharmacology | Adaptor Proteins, Signal Transducing - metabolism | Quinazolines - pharmacology | Insulin-Like Growth Factor I - metabolism | Tyrosine | Phenols | Binding proteins | Analysis | Cancer cells
Journal Article
American Journal of Physiology - Endocrinology And Metabolism, ISSN 0193-1849, 01/2008, Volume 294, Issue 1, pp. 10 - 14
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 09/2017, Volume 102, Issue 9, pp. 3480 - 3490
CONTEXT:Depending on its lipolytic activity, glucagon plays a promising role in obesity treatment. Glucagon-induced growth hormone (GH) release can promote its... 
FOXO | STIMULATION | GROWTH-HORMONE | GHRELIN | ENDOCRINOLOGY & METABOLISM | SECRETION | SUPPRESSION | EXPRESSION | AXIS | Humans | Insulin-Like Growth Factor Binding Proteins - drug effects | Diabetes Mellitus, Type 1 - metabolism | Glucagon - administration & dosage | Male | Insulin-Like Growth Factor I - drug effects | Forkhead Box Protein O1 - drug effects | Dose-Response Relationship, Drug | Statistics, Nonparametric | Adult | Female | Forkhead Box Protein O1 - metabolism | Double-Blind Method | Drug Administration Schedule | Enzyme-Linked Immunosorbent Assay | Growth Hormone - drug effects | Growth Hormone - metabolism | Obesity - physiopathology | Injections, Intramuscular | Blotting, Western | Diabetes Mellitus, Type 1 - drug therapy | Obesity - metabolism | Insulin-Like Growth Factor Binding Proteins - metabolism | Diabetes Mellitus, Type 1 - diagnosis | Insulin-Like Growth Factor I - metabolism | TOR protein | Phosphorylation | Glucagon | Insulin-like growth factor I | Insulin-like growth factor-binding protein 2 | Insulin-like growth factor-binding protein 1 | AKT protein | Insulin-like growth factors | Kinases | Proteins | Biomedical materials | Reduction | FOXO1 protein | Osteosarcoma | Forkhead protein | Insulin-like growth factor-binding protein 3 | Biocompatibility | Lipid metabolism | Protein transport | Translocation | Obesity | Secretion | Diabetes mellitus | Rapamycin | Osteosarcoma cells | Gene expression | Metabolism | Insulin | Biological activity | Nuclear transport | Hepatocytes | Growth hormone
Journal Article
Journal Article