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Nature, ISSN 0028-0836, 08/2007, Volume 448, Issue 7157, pp. 1015 - 1021
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2017, Volume 12, Issue 10, p. e0185775
Limb muscles derive from pax3 expressing precursor cells that migrate from the hypaxial somite into the developing limb bud. Once there they begin to... 
SKELETAL-MUSCLE | ORIGIN | RETINOIC ACID | SONIC HEDGEHOG | SOMITE | MULTIDISCIPLINARY SCIENCES | SF/HGF | CXCR4 | MUSCLE PROGENITOR CELLS | DIFFERENTIATION | EXPRESSION | Insulin-Like Growth Factor I - pharmacology | Podophyllotoxin - pharmacology | Receptor, IGF Type 1 - antagonists & inhibitors | Nitriles - pharmacology | MyoD Protein - genetics | Fibroblast Growth Factors - genetics | Muscle, Skeletal - metabolism | Myogenin - genetics | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Fibroblast Growth Factors - metabolism | Chick Embryo - metabolism | Gene Expression Regulation, Developmental | Muscle, Skeletal - drug effects | PAX3 Transcription Factor - genetics | Insulin-Like Growth Factor II - pharmacology | Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors | Chromones - pharmacology | Butadienes - pharmacology | Muscle Development - physiology | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | PAX3 Transcription Factor - metabolism | MyoD Protein - metabolism | Pyrroles - pharmacology | Animals | Muscle Development - drug effects | Hindlimb - drug effects | Chick Embryo - drug effects | Hindlimb - metabolism | Myogenin - metabolism | Podophyllotoxin - analogs & derivatives | Genetic aspects | Research | Insulin-like growth factor 1 | Myogenesis | Fibroblast growth factor | Insulin-like growth factor I | mRNA | Insulin-like growth factors | Kinases | Limb buds | Signal transduction | Embryology | Developmental stages | Fibroblast growth factor 18 | Pax3 protein | Insulin-like growth factor II | Vascular endothelial growth factor | Growth factors | Recombinant | Myogenin | MyoD protein | Muscles | Gene expression | Insulin | Embryos | 1-Phosphatidylinositol 3-kinase | Myoblasts | Vascular endothelial growth factor receptors | Musculoskeletal system | Inhibitors | Transduction | Differentiation | Beads | Retinoic acid | Cell migration | Fibroblast growth factor receptors
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 11/2010, Volume 25, Issue 11, pp. 2447 - 2459
Efficient osteogenic differentiation and bone formation from mesenchymal stem cells (MSCs) should have clinical applications in treating nonunion fracture... 
bone formation | IGF‐2 | osteoblastic differentiation | BMP‐9 | fracture healing | IGF-2 | BMP-9 | OSTEOBLAST DIFFERENTIATION | PHOSPHATIDYLINOSITOL 3-KINASE | MOUSE | OSTEOBLASTIC DIFFERENTIATION | HEPATIC PROGENITOR CELLS | MESENCHYMAL STEM-CELLS | FRACTURE HEALING | GENE | BONE FORMATION | ENDOCRINOLOGY & METABOLISM | BMP 9 | RECOMBINANT ADENOVIRUSES | MORPHOGENETIC PROTEINS | IGF 2 | MARROW STROMAL CELLS | TRANSGENIC MICE | Bone Matrix - metabolism | Mesenchymal Stromal Cells - enzymology | Growth Differentiation Factor 2 - pharmacology | Growth Differentiation Factor 2 - metabolism | Humans | Alkaline Phosphatase - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Chondrocytes - drug effects | Mesenchymal Stromal Cells - cytology | Insulin-Like Growth Factor Binding Protein 3 - metabolism | Bone Matrix - drug effects | Insulin-Like Growth Factor Binding Protein 4 - metabolism | Insulin-Like Growth Factor II - pharmacology | Fetus | Proto-Oncogene Proteins c-akt - metabolism | Biomarkers - metabolism | Cell Line | Chondrocytes - pathology | Mesenchymal Stromal Cells - drug effects | Calcification, Physiologic - drug effects | Implants, Experimental | Osteogenesis - drug effects | Insulin-Like Growth Factor II - metabolism | Animals | Signal Transduction - drug effects | Cell Differentiation - drug effects | Cell Proliferation - drug effects | Mice | Smad Proteins - metabolism | Mesenchymal Stem Cell Transplantation | Hypertrophy | Original
Journal Article
Journal Article
Journal Article
Development, ISSN 0950-1991, 05/2011, Volume 138, Issue 9, pp. 1795 - 1805
Journal Article
Journal Article
FASEB Journal, ISSN 0892-6638, 03/2004, Volume 18, Issue 3, pp. 469 - 479
Fibroblast proliferation, differentiation into myofibroblasts, and increased collagen synthesis are key events during both normal wound repair and fibrotic... 
TGF-β | Fibrotic tissue | Myofibroblasts | CTGF | SMOOTH MUSCLE ACTIN | fibrotic tissue | FIBRONECTIN MESSENGER-RNAS | HUMAN DERMAL FIBROBLASTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BETA TGF-BETA | CELL BIOLOGY | TGF-beta | COLLAGEN-SYNTHESIS | HUMAN SKIN FIBROBLASTS | BIOLOGY | GENE-EXPRESSION | ANCHORAGE-INDEPENDENT GROWTH | TRANSFORMING-GROWTH-FACTOR | myofibroblasts | ALPHA-5-BETA-1 INTEGRIN | Insulin-Like Growth Factor II - physiology | Epidermal Growth Factor - physiology | DNA Replication - drug effects | Humans | Kidney | Actins - genetics | Intercellular Signaling Peptides and Proteins - physiology | Cell Line - cytology | RNA, Messenger - biosynthesis | Cell Line - drug effects | Insulin-Like Growth Factor II - pharmacology | Myoblasts - cytology | Collagen - biosynthesis | Collagen - genetics | Fibroblasts - metabolism | Transforming Growth Factor beta1 | Actins - biosynthesis | Immediate-Early Proteins - physiology | Transforming Growth Factor beta - physiology | Rats | Recombinant Proteins - pharmacology | Fibroblasts - pathology | Gene Expression Regulation - drug effects | Transforming Growth Factor beta - pharmacology | Animals | Cell Differentiation - drug effects | Intercellular Signaling Peptides and Proteins - pharmacology | Fibroblasts - drug effects | Immediate-Early Proteins - pharmacology | Fibrosis | Signal Transduction - physiology | Fibroblasts - cytology | Wound Healing - physiology | Epidermal Growth Factor - pharmacology | Connective Tissue Growth Factor
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2012, Volume 7, Issue 2, p. e32191
The ability of embryonic stem cells to differentiate into endothelium and form functional blood vessels has been well established and can potentially be... 
PROGENITOR CELLS | FACTOR 1-ALPHA | CYCLOLIGNAN PPP | IGF-I | SIGNALING PATHWAY | MULTIDISCIPLINARY SCIENCES | ENDOTHELIAL-CELLS | MOUSE MODEL | FACTOR-I RECEPTOR | EXPRESSION | HYPOXIA-INDUCIBLE FACTOR-2-ALPHA | Neovascularization, Physiologic - drug effects | Receptor, IGF Type 1 - metabolism | Insulin-Like Growth Factor I - pharmacology | Podophyllotoxin - pharmacology | Receptor, IGF Type 1 - antagonists & inhibitors | Embryonic Stem Cells - cytology | Mesoderm - drug effects | Vascular Endothelial Growth Factor A - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Mesoderm - cytology | Receptor, IGF Type 2 - metabolism | Embryoid Bodies - metabolism | Embryoid Bodies - cytology | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Insulin-Like Growth Factor II - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Mesoderm - embryology | Embryonic Stem Cells - enzymology | Embryonic Stem Cells - physiology | Endothelium - embryology | Embryoid Bodies - drug effects | Endothelium - cytology | Receptor, IGF Type 2 - antagonists & inhibitors | Endothelium - drug effects | Animals | Carrier Proteins - metabolism | Embryonic Stem Cells - drug effects | Signal Transduction - drug effects | Cell Differentiation - drug effects | Models, Biological | Protein Stability - drug effects | Mice | Podophyllotoxin - analogs & derivatives | Viral antibodies | Stem cells | Antibodies | Transplantation | Neovascularization | Embryonic stem cells | Vascular endothelial growth factor | Health aspects | Diabetes therapy | Endothelium | Cell culture | Insulin-like growth factor I | Embryo cells | Mesoderm | Blood vessels | Pharmacology | Insulin-like growth factors | Kinases | Insulin | Endothelial cells | Vascularization | Angiogenesis | Signaling | Receptors | Embryogenesis | Rodents | Insulin-like growth factor II | Differentiation | Growth factors
Journal Article