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2005, Advances in experimental medicine and biology, ISBN 9780387251196, Volume 567., 421
Insulin-like growth factor (IGF)-I is a widely expressed growth factor with diverse effects on many tissues throughout development and in adult life. The... 
Somatotropin | Somatomedin | Peptides | Neurology | Maternal and Child Health | Diabetes | Medicine & Public Health | Endocrinology
Book
Nature, ISSN 0028-0836, 07/2012, Volume 487, Issue 7408, pp. 505 - 509
Mutationally activated kinases define a clinically validated class of targets for cancer drug therapy(1). However, the efficacy of kinase inhibitors in... 
CELL LUNG-CANCER | SURVIVAL | HETEROGENEITY | ACTIVATION | RECEPTOR TYROSINE KINASES | THERAPY | MET AMPLIFICATION | MULTIDISCIPLINARY SCIENCES | ACQUIRED-RESISTANCE | SENSITIVITY | TUMOR-CELLS | Receptor, ErbB-2 - genetics | Humans | Receptor, ErbB-2 - metabolism | Melanoma - enzymology | Phosphatidylinositol 3-Kinases - metabolism | Hepatocyte Growth Factor - pharmacology | Breast Neoplasms - metabolism | Melanoma - genetics | Female | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Cell Survival - drug effects | Melanoma - pathology | Receptor Protein-Tyrosine Kinases - metabolism | Sulfonamides - pharmacology | Breast Neoplasms - drug therapy | Hepatocyte Growth Factor - metabolism | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Breast Neoplasms - genetics | Signal Transduction - drug effects | Breast Neoplasms - pathology | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Cell Line, Tumor | Ligands | Protein Kinase Inhibitors - pharmacology | Quinazolines - pharmacology | Drug Resistance, Neoplasm - drug effects | Mitogen-Activated Protein Kinases - metabolism | Antimitotic agents | Physiological aspects | Antineoplastic agents | Growth factors | Health aspects | Phosphotransferases | Substance abuse treatment | Epidermal growth factor | Rodents | Biomarkers | Breast cancer | Insulin-like growth factors | Kinases | Drug resistance | Tumors
Journal Article
Nature Reviews Cancer, ISSN 1474-175X, 03/2012, Volume 12, Issue 3, pp. 159 - 169
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 07/2012, Volume 104, Issue 13, pp. 975 - 981
The success of targeted therapies for cancer is undisputed; strong preclinical evidence has resulted in the approval of several new agents for cancer... 
LUNG-CANCER | KINASE INHIBITION | SOLID TUMORS | ONCOLOGY | PHASE-II | IGF RECEPTOR | MONOCLONAL-ANTIBODY | BREAST-CANCER-CELLS | ANTITUMOR-ACTIVITY | FACTOR-I RECEPTOR | SARCOMA FAMILY | Neoplasms - metabolism | Breast Neoplasms - surgery | Lung Neoplasms - drug therapy | Receptor, IGF Type 1 - metabolism | Receptor, IGF Type 1 - antagonists & inhibitors | Carcinoma, Squamous Cell - metabolism | Humans | Lung Neoplasms - metabolism | Antibodies, Monoclonal - therapeutic use | Antineoplastic Agents - therapeutic use | Endocrine Disruptors | Breast Neoplasms - metabolism | Early Termination of Clinical Trials | Human Growth Hormone - metabolism | Biomarkers, Tumor - metabolism | Female | Antineoplastic Agents - pharmacology | Human Growth Hormone - administration & dosage | Hyperinsulinism - complications | Ovariectomy | Signal Transduction | Risk Factors | Treatment Outcome | Clinical Trials as Topic | Evidence-Based Medicine | Disease Progression | Breast Neoplasms - prevention & control | Neoplasms - drug therapy | Carcinoma, Squamous Cell - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Body Height | Hypophysectomy | Immunoglobulins, Intravenous | Insulin-Like Growth Factor I - metabolism | Physiological aspects | Care and treatment | Enzyme inhibitors | Research | Insulin-like growth factor 1 | Cancer
Journal Article
Endocrine Reviews, ISSN 0163-769X, 08/2009, Volume 30, Issue 5, pp. 494 - 535
Journal Article