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2005, Advances in experimental medicine and biology, ISBN 9780387251196, Volume 567, 421
Insulin-like growth factor (IGF)-I is a widely expressed growth factor with diverse effects on many tissues throughout development and in adult life. The... 
Somatotropin | Somatomedins | Insulin-Like Growth Factor II | Peptides | Growth Hormone | Somatomedin | Insulin-Like Growth Factor I | Neurology | Maternal and Child Health | Diabetes | Medicine & Public Health | Endocrinology
Book
1992, Oxford medical publications., ISBN 9780198542704, xiii, 284
Book
PLoS ONE, ISSN 1932-6203, 10/2017, Volume 12, Issue 10, pp. e0185775 - e0185775
Limb muscles derive from pax3 expressing precursor cells that migrate from the hypaxial somite into the developing limb bud. Once there they begin to... 
SKELETAL-MUSCLE | ORIGIN | RETINOIC ACID | SONIC HEDGEHOG | SOMITE | MULTIDISCIPLINARY SCIENCES | SF/HGF | CXCR4 | MUSCLE PROGENITOR CELLS | DIFFERENTIATION | EXPRESSION | Insulin-Like Growth Factor I - pharmacology | Podophyllotoxin - pharmacology | Receptor, IGF Type 1 - antagonists & inhibitors | Nitriles - pharmacology | MyoD Protein - genetics | Fibroblast Growth Factors - genetics | Muscle, Skeletal - metabolism | Myogenin - genetics | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Fibroblast Growth Factors - metabolism | Chick Embryo - metabolism | Gene Expression Regulation, Developmental | Muscle, Skeletal - drug effects | PAX3 Transcription Factor - genetics | Insulin-Like Growth Factor II - pharmacology | Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors | Chromones - pharmacology | Butadienes - pharmacology | Muscle Development - physiology | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | PAX3 Transcription Factor - metabolism | MyoD Protein - metabolism | Pyrroles - pharmacology | Animals | Muscle Development - drug effects | Hindlimb - drug effects | Chick Embryo - drug effects | Hindlimb - metabolism | Myogenin - metabolism | Podophyllotoxin - analogs & derivatives | Genetic aspects | Research | Insulin-like growth factor 1 | Myogenesis | Fibroblast growth factor | Insulin-like growth factor I | mRNA | Insulin-like growth factors | Kinases | Limb buds | Signal transduction | Embryology | Developmental stages | Fibroblast growth factor 18 | Pax3 protein | Insulin-like growth factor II | Vascular endothelial growth factor | Growth factors | Recombinant | Myogenin | MyoD protein | Muscles | Gene expression | Insulin | Embryos | 1-Phosphatidylinositol 3-kinase | Myoblasts | Vascular endothelial growth factor receptors | Musculoskeletal system | Inhibitors | Transduction | Differentiation | Beads | Retinoic acid | Cell migration | Fibroblast growth factor receptors | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 07/2012, Volume 487, Issue 7408, pp. 505 - 509
Mutationally activated kinases define a clinically validated class of targets for cancer drug therapy(1). However, the efficacy of kinase inhibitors in... 
CELL LUNG-CANCER | SURVIVAL | HETEROGENEITY | ACTIVATION | RECEPTOR TYROSINE KINASES | THERAPY | MET AMPLIFICATION | MULTIDISCIPLINARY SCIENCES | ACQUIRED-RESISTANCE | SENSITIVITY | TUMOR-CELLS | Receptor, ErbB-2 - genetics | Humans | Receptor, ErbB-2 - metabolism | Melanoma - enzymology | Phosphatidylinositol 3-Kinases - metabolism | Hepatocyte Growth Factor - pharmacology | Breast Neoplasms - metabolism | Melanoma - genetics | Female | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Cell Survival - drug effects | Melanoma - pathology | Receptor Protein-Tyrosine Kinases - metabolism | Sulfonamides - pharmacology | Breast Neoplasms - drug therapy | Hepatocyte Growth Factor - metabolism | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Breast Neoplasms - genetics | Signal Transduction - drug effects | Breast Neoplasms - pathology | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Cell Line, Tumor | Ligands | Protein Kinase Inhibitors - pharmacology | Quinazolines - pharmacology | Drug Resistance, Neoplasm - drug effects | Mitogen-Activated Protein Kinases - metabolism | Antimitotic agents | Physiological aspects | Antineoplastic agents | Growth factors | Health aspects | Phosphotransferases | Substance abuse treatment | Epidermal growth factor | Rodents | Biomarkers | Breast cancer | Insulin-like growth factors | Kinases | Drug resistance | Tumors | Index Medicus
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, pp. e62076 - e62076
Tenascin C (TNC) is an extracellular matrix protein that is upregulated during development as well as tissue remodeling. TNC is comprised of multiple... 
METASTATIC NICHE | FUSION | BIOMIMETIC MATERIALS | SRC | CELL-MIGRATION | MULTIDISCIPLINARY SCIENCES | BIOLOGICAL-ACTIVITY | EXTRACELLULAR-MATRIX | HEPARIN | PROTEINS | EXPRESSION | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Surface Plasmon Resonance | Peptide Fragments - metabolism | Proto-Oncogene Proteins c-sis - metabolism | Humans | Transforming Growth Factor beta1 - metabolism | Vascular Endothelial Growth Factor A - metabolism | Tenascin - metabolism | Insulin-Like Growth Factor Binding Proteins - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Neurotrophin 3 - metabolism | HEK293 Cells | Fibroblast Growth Factor 2 - metabolism | Fibronectins | Physiological aspects | Amino acids | Anticoagulants (Medicine) | Binding proteins | Growth factors | Protein binding | Tenascin | Bioengineering | Fibroblast growth factor | Physiological effects | Platelet-derived growth factor | Genes | Transforming growth factor-b | Insulin-like growth factors | Neurotrophin 3 | Fibronectin | Cell adhesion & migration | Proteins | Biomedical materials | Extracellular matrix | Life sciences | Matrix protein | Neurotrophins | Vascular endothelial growth factor | Recombinant | Binding | Fibroblast growth factor 2 | Engineering schools | Tenascin C | Tissue engineering | Cloning | Insulin | Platelet-derived growth factor BB | Biological activity | Stem cells | Affinity | Surface plasmon resonance | Kinetics | Heparin | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2012, Volume 7, Issue 2, pp. e32191 - e32191
The ability of embryonic stem cells to differentiate into endothelium and form functional blood vessels has been well established and can potentially be... 
PROGENITOR CELLS | FACTOR 1-ALPHA | CYCLOLIGNAN PPP | IGF-I | SIGNALING PATHWAY | MULTIDISCIPLINARY SCIENCES | ENDOTHELIAL-CELLS | MOUSE MODEL | FACTOR-I RECEPTOR | EXPRESSION | HYPOXIA-INDUCIBLE FACTOR-2-ALPHA | Neovascularization, Physiologic - drug effects | Receptor, IGF Type 1 - metabolism | Insulin-Like Growth Factor I - pharmacology | Podophyllotoxin - pharmacology | Receptor, IGF Type 1 - antagonists & inhibitors | Embryonic Stem Cells - cytology | Mesoderm - drug effects | Vascular Endothelial Growth Factor A - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Mesoderm - cytology | Receptor, IGF Type 2 - metabolism | Embryoid Bodies - metabolism | Embryoid Bodies - cytology | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Insulin-Like Growth Factor II - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Mesoderm - embryology | Embryonic Stem Cells - enzymology | Embryonic Stem Cells - physiology | Endothelium - embryology | Embryoid Bodies - drug effects | Endothelium - cytology | Receptor, IGF Type 2 - antagonists & inhibitors | Endothelium - drug effects | Animals | Carrier Proteins - metabolism | Embryonic Stem Cells - drug effects | Signal Transduction - drug effects | Cell Differentiation - drug effects | Models, Biological | Protein Stability - drug effects | Mice | Podophyllotoxin - analogs & derivatives | Viral antibodies | Stem cells | Antibodies | Transplantation | Neovascularization | Embryonic stem cells | Vascular endothelial growth factor | Health aspects | Diabetes therapy | Endothelium | Cell culture | Insulin-like growth factor I | Embryo cells | Mesoderm | Blood vessels | Pharmacology | Insulin-like growth factors | Kinases | Insulin | Endothelial cells | Vascularization | Angiogenesis | Signaling | Receptors | Embryogenesis | Rodents | Insulin-like growth factor II | Differentiation | Growth factors | Index Medicus
Journal Article
Journal of Periodontology, ISSN 0022-3492, 08/2013, Volume 84, Issue 8, pp. 1180 - 1190
Background: Alveolar bone loss can be a major clinical concern affecting both functionality and esthetics. Osteoblasts are the main cells charged with the... 
intercellular signaling peptides and proteins | osteoblasts | Blood platelets | platelet‐rich plasma | regeneration | bone and bones | Regeneration | Intercellular signaling peptides and proteins | Bone and bones | Osteoblasts | Platelet-rich plasma | STEM-CELLS | DENTAL IMPLANTS | CHEMOTACTIC MIGRATION | MECHANISMS | MEDICINE | platelet-rich plasma | RESPONSES | IN-VITRO | PLATELETS | DENTISTRY, ORAL SURGERY & MEDICINE | MORPHOGENETIC PROTEIN-2 | FIBRIN MATRICES | Hepatocyte Growth Factor - therapeutic use | Intercellular Signaling Peptides and Proteins - analysis | Plasma | Platelet-Derived Growth Factor - therapeutic use | Proto-Oncogene Proteins c-sis - analysis | Humans | Middle Aged | Alveolar Process - drug effects | Male | Autocrine Communication - drug effects | Endothelial Growth Factors - analysis | Alveolar Process - cytology | Osteocalcin - therapeutic use | Platelet-Derived Growth Factor - analysis | Aged, 80 and over | Alkaline Phosphatase - analysis | Adult | Female | Cell Culture Techniques | Endothelial Growth Factors - therapeutic use | Transforming Growth Factor beta1 - analysis | Insulin-Like Growth Factor I - therapeutic use | Osteocalcin - analysis | Bone Regeneration - drug effects | Hepatocyte Growth Factor - analysis | Osteoblasts - drug effects | Vascular Endothelial Growth Factor A - therapeutic use | Cells, Cultured | Vascular Endothelial Growth Factor A - analysis | Chemotaxis - drug effects | Insulin-Like Growth Factor I - analysis | Cell Movement - drug effects | Transforming Growth Factor beta1 - therapeutic use | Proto-Oncogene Proteins c-sis - therapeutic use | Platelet-Rich Plasma | Aged | Cell Proliferation - drug effects | Collagen Type I - analysis | Intercellular Signaling Peptides and Proteins - therapeutic use | Collagen Type I - therapeutic use | Index Medicus | Dentistry
Journal Article
Annals of Internal Medicine, ISSN 0003-4819, 10/2008, Volume 149, Issue 7, pp. 461 - 471
Journal Article
15.