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index medicus (131) 131
humans (114) 114
animals (77) 77
integrins (63) 63
signal transduction (43) 43
cell line, tumor (41) 41
cancer (40) 40
integrin (38) 38
mice (34) 34
oncology (33) 33
cell biology (32) 32
metastasis (32) 32
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cell adhesion (30) 30
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integrin alpha6beta4 - metabolism (23) 23
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integrins - metabolism (22) 22
laminin (21) 21
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cell adhesion & migration (20) 20
biochemistry & molecular biology (19) 19
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extracellular matrix (18) 18
phosphorylation (18) 18
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alpha-6-beta-4 integrin (15) 15
apoptosis (15) 15
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integrin alpha6beta4 - genetics (14) 14
cell adhesion - drug effects (13) 13
cell movement - drug effects (13) 13
cells, cultured (13) 13
genetic aspects (13) 13
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adhesion (12) 12
biology (12) 12
breast neoplasms - metabolism (12) 12
breast neoplasms - pathology (12) 12
cell proliferation (12) 12
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integrins - physiology (12) 12
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tumors (12) 12
antineoplastic agents - pharmacology (11) 11
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cell adhesion - physiology (11) 11
cell adhesion molecules - metabolism (11) 11
focal adhesion kinase (11) 11
immunohistochemistry (11) 11
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kinases (11) 11
medicine (11) 11
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science (11) 11
signal transduction - drug effects (11) 11
angiogenesis (10) 10
blotting, western (10) 10
cells (10) 10
development and progression (10) 10
health aspects (10) 10
integrins - antagonists & inhibitors (10) 10
life sciences (10) 10
protein binding (10) 10
rats (10) 10
signaling (10) 10
flow cytometry (9) 9
gene expression regulation, neoplastic (9) 9
medicine & public health (9) 9
neoplasms - pathology (9) 9
physiology (9) 9
rna, small interfering - genetics (9) 9
antibodies (8) 8
biochemistry, general (8) 8
cell survival (8) 8
enzyme inhibitors - pharmacology (8) 8
epithelial cells (8) 8
growth factors (8) 8
integrin alpha6beta4 - antagonists & inhibitors (8) 8
integrin beta4 - metabolism (8) 8
keratinocytes - metabolism (8) 8
ligands (8) 8
metastases (8) 8
mice, nude (8) 8
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phosphatidylinositol 3-kinases - metabolism (8) 8
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by Hoshino, Ayuko and Costa-Silva, Bruno and Shen, Tang-Long and Rodrigues, Goncalo and Hashimoto, Ayako and Tesic Mark, Milica and Molina, Henrik and Kohsaka, Shinji and Di Giannatale, Angela and Ceder, Sophia and Singh, Swarnima and Williams, Caitlin and Soplop, Nadine and Uryu, Kunihiro and Pharmer, Lindsay and King, Tari and Bojmar, Linda and Davies, Alexander E and Ararso, Yonathan and Zhang, Tuo and Zhang, Haiying and Hernandez, Jonathan and Weiss, Joshua M and Dumont-Cole, Vanessa D and Kramer, Kimberly and Wexler, Leonard H and Narendran, Aru and Schwartz, Gary K and Healey, John H and Sandstrom, Per and Jørgen Labori, Knut and Kure, Elin H and Grandgenett, Paul M and Hollingsworth, Michael A and De Sousa, Maria and Kaur, Sukhwinder and Jain, Maneesh and Mallya, Kavita and Batra, Surinder K and Jarnagin, William R and Brady, Mary S and Fodstad, Oystein and Muller, Volkmar and Pantel, Klaus and Minn, Andy J and Bissell, Mina J and Garcia, Benjamin A and Kang, Yibin and Rajasekhar, Vinagolu K and Ghajar, Cyrus M and Matei, Irina and Peinado, Hector and Bromberg, Jacqueline and Lyden, David and Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States) and Weill Cornell Medicine, New York, NY (United States) and Memorial Sloan Kettering Cancer Center, New York, NY (United States) and Medicinska fakulteten and Region Östergötland and Kirurgiska kliniken US and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Avdelningen för kliniska vetenskaper and Centrum för kirurgi, ortopedi och cancervård
Nature, ISSN 0028-0836, 11/2015, Volume 527, Issue 7578, pp. 329 - 335
Ever since Stephen Paget's 1889 hypothesis, metastatic organotropism has remained one of cancer's greatest mysteries. Here we demonstrate that exosomes from... 
CELLS | BONE METASTASES | VESICLES | BREAST-CANCER METASTASIS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | GROWTH | NICHE | MICROVESICLES | PROTEINS | PROTEOMICS | Exosomes - metabolism | Tropism | Phosphorylation | Epithelial Cells - metabolism | Receptors, Vitronectin - antagonists & inhibitors | Humans | Lung - cytology | Integrin beta4 - metabolism | Integrins - metabolism | Brain - metabolism | Integrin alpha6beta1 - metabolism | S100 Proteins - genetics | Neoplasm Metastasis - prevention & control | Female | Kupffer Cells - metabolism | Lung - metabolism | Receptors, Vitronectin - metabolism | Epithelial Cells - cytology | Integrin alpha6beta4 - metabolism | Fibroblasts - metabolism | Biomarkers - metabolism | Brain - cytology | Kupffer Cells - cytology | Endothelial Cells - metabolism | Liver - metabolism | Mice, Inbred C57BL | Integrin alpha6beta4 - antagonists & inhibitors | Organ Specificity | Animals | Endothelial Cells - cytology | Neoplasm Metastasis - pathology | Cell Line, Tumor | Integrin beta Chains - metabolism | Fibroblasts - cytology | Liver - cytology | Mice | Genes, src | Integrins - antagonists & inhibitors | Complications and side effects | Development and progression | Cell organelles | Metastasis | Health aspects | Integrins | Tumors | Studies | Microscopy | Liver | Melanoma | Fibroblasts | Breast cancer | Chemokines | Index Medicus | mechanisms of disease | cancer microenvironment | BASIC BIOLOGICAL SCIENCES | metastasis | 60 APPLIED LIFE SCIENCES | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
Cancer Prevention Research, ISSN 1940-6207, 10/2008, Volume 1, Issue 5, pp. 385 - 391
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 11/2016, Volume 17, Issue 11, pp. 1862 - 1862
In previous studies, we identified 29 tumor-associated antigens (TAAs) and isolated 488 human monoclonal antibodies (mAbs) that specifically bind to one of the... 
Cancer-associated antigens | Phage-display antibody library | Histochemical analysis | Combination therapy | Therapeutic antibody | THERAPEUTICS | histochemical analysis | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIBRARY | RECEPTOR | phage-display antibody library | CHEMISTRY, MULTIDISCIPLINARY | cancer-associated antigens | THERAPY | IN-VIVO | therapeutic antibody | IMMUNOTHERAPIES | combination therapy | DOMAIN-CONTAINING PROTEIN-1 | MONOCLONAL-ANTIBODIES | Integrin alpha6beta4 - immunology | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Receptor, ErbB-2 - genetics | Antibodies, Monoclonal - biosynthesis | Epithelial Cells - drug effects | Humans | Antibodies, Monoclonal - therapeutic use | Antineoplastic Agents - therapeutic use | Peptide Library | Bronchi - immunology | Antineoplastic Agents - metabolism | Bronchi - drug effects | Epitopes - immunology | Receptor, ErbB-2 - antagonists & inhibitors | Receptor, ErbB-2 - immunology | Receptors, Transferrin - genetics | Bronchi - pathology | Molecular Targeted Therapy - methods | Lung Neoplasms - genetics | Antigens, Neoplasm - genetics | Receptor, Epidermal Growth Factor - immunology | Gene Expression | Antigens, Neoplasm - immunology | Integrin alpha6beta4 - genetics | Integrin alpha6beta4 - antagonists & inhibitors | Epithelial Cells - pathology | Bronchi - surgery | Lung Neoplasms - immunology | Epithelial Cells - immunology | Receptors, Transferrin - immunology | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Lung Neoplasms - surgery | Epitopes - chemistry | Receptors, Transferrin - antagonists & inhibitors | Antigens, Neoplasm - classification | Antigens | Cancer therapies | Lung cancer | Index Medicus
Journal Article
BMC Cell Biology, ISSN 1471-2121, 12/2013, Volume 14, Issue 1, pp. 53 - 53
Journal Article
Journal Article
Molecular Cancer Research, ISSN 1541-7786, 12/2010, Volume 8, Issue 12, pp. 1571 - 1578
Journal Article
Journal Article
Neoplasia, ISSN 1476-5586, 2012, Volume 14, Issue 8, pp. 678 - IN3
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2017, Volume 12, Issue 9, pp. e0184285 - e0184285
We have reported that integrins crosstalk with growth factors through direct binding to growth factors (e.g., fibroblast growth factor-1, insulin-like growth... 
CELLS | ANTAGONIST | DEFECTIVE MUTANT | ALPHA-V-BETA-3 | MULTIDISCIPLINARY SCIENCES | ALPHA-6-BETA-4 | FACTOR-I | TERNARY COMPLEX-FORMATION | Amino Acid Sequence