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Journal of the National Cancer Institute, ISSN 0027-8874, 03/2012, Volume 104, Issue 6, pp. 461 - 475
Background Angiopoietin-2 (Ang2), a ligand for endothelial TEK (Tie2) tyrosine kinase receptor, is induced in hypoxic endothelial cells of tumors, where it... 
LYMPHATIC VESSELS | TRANSGENE EXPRESSION | ANGIOGENESIS | ONCOLOGY | IN-VIVO | GENE-THERAPY | VEGF-C | TUMOR-GROWTH | CANCER | RECEPTOR TYROSINE KINASE | TIE2 RECEPTOR | Immunohistochemistry | Antibodies, Blocking - metabolism | Up-Regulation | Immunoprecipitation | Melanoma - blood supply | Coculture Techniques | Endothelium, Vascular - drug effects | Immunoblotting | Transplantation, Heterologous | Antibodies, Blocking - pharmacology | Angiopoietin-2 - metabolism | Cell Hypoxia | Retinal Vessels - pathology | Lung Neoplasms - secondary | Intercellular Junctions - pathology | Female | Neovascularization, Pathologic - prevention & control | Receptor, TIE-2 - metabolism | Lymphangiogenesis | Lung Neoplasms - blood supply | Microscopy, Electron, Transmission | Retinal Vessels - metabolism | Intercellular Junctions - metabolism | Angiogenesis Inhibitors - pharmacology | Mice, Transgenic | Lymphatic Metastasis | Retinal Vessels - drug effects | Mice, SCID | Melanoma - secondary | Animals | Neovascularization, Pathologic - drug therapy | Intercellular Junctions - drug effects | Endothelium, Vascular - pathology | Mice | Mice, Inbred BALB C | Neovascularization, Pathologic - metabolism | Angiopoietin-2 - antagonists & inhibitors | Endothelial Cells - pathology | Endothelial Cells - drug effects | Junctional complexes (Epithelium) | Lung cancer | Cell junctions | Physiological aspects | Development and progression | Models | Metastasis | Research | Growth factor receptors | Studies | Lungs | Medical treatment | Tumors | Index Medicus
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 02/2010, Volume 21, Issue 4, pp. 584 - 596
Vascular endothelial (VE)-cadherin is a cell-cell adhesion molecule involved in endothelial barrier functions. Previously, we reported that cAMP-Epac-Rap1... 
BARRIER DYSFUNCTION | F-ACTIN | ADHESION | COMPLEX | EPITHELIAL-CELLS | RAP1 EFFECTOR | VE-CADHERIN | SRC ACTIVITY | ADHERENS JUNCTIONS | EXCHANGE FACTORS | CELL BIOLOGY | RNA, Small Interfering - genetics | Platelet Endothelial Cell Adhesion Molecule-1 - genetics | Thiazolidines - metabolism | Cadherins - metabolism | Fluorescence Recovery After Photobleaching | alpha Catenin - metabolism | Humans | Actins - metabolism | Guanosine Triphosphate - metabolism | Antigens, CD - genetics | Recombinant Fusion Proteins - metabolism | Actins - genetics | Antigens, CD - metabolism | Colforsin - metabolism | Guanine Nucleotide Exchange Factors - metabolism | Platelet Endothelial Cell Adhesion Molecule-1 - metabolism | Cadherins - genetics | Cyclic AMP - metabolism | Bridged Bicyclo Compounds, Heterocyclic - metabolism | Cell Line | rap1 GTP-Binding Proteins - metabolism | Guanine Nucleotide Exchange Factors - genetics | Endothelial Cells - metabolism | Intercellular Junctions - metabolism | beta Catenin - metabolism | beta Catenin - genetics | Animals | Endothelial Cells - cytology | Cyclic AMP Response Element-Binding Protein - metabolism | Recombinant Fusion Proteins - genetics | Signal Transduction - physiology | alpha Catenin - genetics | rap1 GTP-Binding Proteins - genetics | RNA, Small Interfering - metabolism | Index Medicus
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