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2008, ISBN 9780470025512, xx, 389
Book
Science, ISSN 0036-8075, 5/2012, Volume 336, Issue 6081, pp. 579 - 582
Developing animals frequently adjust their growth programs and/or their maturation or metamorphosis to compensate for growth disturbances (such as injury or... 
Insect larvae | Pupariation | Animals | DNA damage | Drosophila | REPORTS | Larval development | Genetic mutation | Metamorphosis | Genotypes | Tumors | DROSOPHILA-MELANOGASTER | PUPARIATION | DISKS | MULTIDISCIPLINARY SCIENCES | GENES | SIZE | Intercellular Signaling Peptides and Proteins - chemistry | Molecular Sequence Data | Intracellular Signaling Peptides and Proteins - metabolism | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Drosophila melanogaster - metabolism | Neoplasms, Experimental - pathology | Intercellular Signaling Peptides and Proteins - metabolism | Metamorphosis, Biological - genetics | Gene Expression Regulation, Developmental | Larva - growth & development | Ecdysone - biosynthesis | Imaginal Discs - growth & development | Neoplasms, Experimental - genetics | Pupa - growth & development | Intracellular Signaling Peptides and Proteins - genetics | Genes, Insect | Amino Acid Sequence | Imaginal Discs - physiology | Intercellular Signaling Peptides and Proteins - genetics | Drosophila Proteins - chemistry | Peptide Initiation Factors - metabolism | Peptide Initiation Factors - genetics | Regeneration | Ethyl Methanesulfonate - pharmacology | Drosophila melanogaster - growth & development | Drosophila Proteins - genetics | Neoplasms, Experimental - metabolism | Apoptosis | Physiological aspects | Animal development | Peptides | Health aspects | Insulin | Insulin-like growth factors | Insects | Maturation | Index Medicus | Endocrine systems | Communication systems | Disks | Adults | Damage | Delay
Journal Article
Journal Article
2007, Advances in experimental medicine and biology, ISBN 038770955X, Volume 600., xiv, 147
The book summarizes our progress in understanding the receptor and intracellular signaling mechanisms utilized by a family of proteins called the semaphorins.... 
Semaphorins | Cell receptors | Cellular signal transduction | Cancer Research | Neurosciences | Biomedicine | Immunology
Book
Gastroenterology, ISSN 0016-5085, 2011, Volume 140, Issue 4, pp. 1230 - 1240.e7
Background & Aims Ablation of Notch signaling within the intestinal epithelium results in loss of proliferating crypt progenitors due to their conversion into... 
Gastroenterology and Hepatology | Gene Regulation | GI Development | Knockout Mice | Intestinal Stem Cells | GAMMA-SECRETASE INHIBITORS | SELF-RENEWAL | INHIBITS TUMOR-GROWTH | LINEAGE COMMITMENT | GOBLET CELLS | GENE | COLORECTAL-CANCER | IN-VIVO | DIFFERENTIATION | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | Intestinal Mucosa - metabolism | Receptors, G-Protein-Coupled - metabolism | Cell Count | Intracellular Signaling Peptides and Proteins - metabolism | Intestinal Mucosa - cytology | Intercellular Signaling Peptides and Proteins - metabolism | Kruppel-Like Transcription Factors - metabolism | Serrate-Jagged Proteins | Membrane Proteins - metabolism | Cell Differentiation - physiology | Intracellular Signaling Peptides and Proteins - genetics | Jagged-1 Protein | Calcium-Binding Proteins - metabolism | Adult Stem Cells - cytology | Membrane Proteins - genetics | Intercellular Signaling Peptides and Proteins - genetics | Receptor, Notch1 - metabolism | Goblet Cells - metabolism | Mice, Knockout | Cell Division - physiology | Adult Stem Cells - metabolism | Animals | Homeostasis - physiology | Signal Transduction - physiology | Mice | Receptor, Notch1 - genetics | Kruppel-Like Transcription Factors - genetics | Calcium-Binding Proteins - genetics | Goblet Cells - cytology | Index Medicus | Abridged Index Medicus | GI development | knockout mice | gene regulation | intestinal stem cells
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2011, Volume 286, Issue 9, pp. 7018 - 7026
The Hippo pathway restricts the activity of transcriptional co-activators TAZ and YAP by phosphorylating them for cytoplasmic sequestration or degradation. In... 
YES-ASSOCIATED PROTEIN | EPITHELIAL-MESENCHYMAL TRANSITION | CELL CONTACT INHIBITION | WW DOMAIN | GROWTH-CONTROL | ORGAN SIZE CONTROL | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | ONCOGENIC TRANSFORMATION | BINDING | CANCER | Adaptor Proteins, Signal Transducing - chemistry | Protein Interaction Domains and Motifs - physiology | Humans | Intercellular Signaling Peptides and Proteins - chemistry | Cytoplasm - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Phosphoproteins - metabolism | Phosphoproteins - chemistry | Intercellular Signaling Peptides and Proteins - metabolism | HEK293 Cells | Membrane Proteins - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Protein Structure, Tertiary | Membrane Proteins - genetics | Intercellular Signaling Peptides and Proteins - genetics | Phosphoproteins - genetics | Cell Division - physiology | Transcription, Genetic - physiology | Membrane Proteins - chemistry | Intracellular Signaling Peptides and Proteins - chemistry | Adaptor Proteins, Signal Transducing - genetics | Signal Transduction - physiology | Connective Tissue Growth Factor - genetics | Adaptor Proteins, Signal Transducing - metabolism | Connective Tissue Growth Factor - metabolism | Index Medicus | Gene Transcription | Transcription Coactivators | Signal Transduction | AmotL1 | YAP | Transcription Factors | Serine Threonine Protein Kinase | Hippo Pathway | TAZ | Amot
Journal Article
Science, ISSN 0036-8075, 5/2012, Volume 336, Issue 6081, pp. 582 - 585
Little is known about how organ growth is monitored and coordinated with the developmental timing in complex organisms. In insects, impairment of larval tissue... 
Insect larvae | Pupariation | Drosophila | REPORTS | Delay lines | Coordinate systems | Instars | Larval development | Metamorphosis | Developmental delay | Propagation delay | ORGANS | REGENERATION | DISKS | MULTIDISCIPLINARY SCIENCES | PATTERN FORMATION | WING IMAGINAL DISCS | MELANOGASTER | PUPARIATION | Genes, Insect | Sequence Deletion | Larva - metabolism | Intercellular Signaling Peptides and Proteins - genetics | JNK Mitogen-Activated Protein Kinases - metabolism | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | MAP Kinase Signaling System | Brain - metabolism | Drosophila melanogaster - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Metamorphosis, Biological | Animals | Wings, Animal - growth & development | RNA Interference | Time Factors | Gene Expression Regulation, Developmental | Larva - growth & development | Ecdysone - biosynthesis | Imaginal Discs - growth & development | Drosophila melanogaster - growth & development | Larva - genetics | Drosophila Proteins - genetics | Peptides | Growth | Developmental biology | Physiological aspects | Research | Tissues | Health aspects | Signal transduction | Tissue | Insects | Index Medicus | Endocrine systems | Communication systems | Disks | Adults | Damage | Delay | Brain | Drosophila Proteins | Wing | Intercellular Signaling Peptides and Proteins | Life Sciences | Larva | Imaginal Discs | JNK Mitogen-Activated Protein Kinases | Development Biology | Ecdysone | Drosophila melanogaster
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 10/2015, Volume 43, Issue 4, pp. 803 - 816
Journal Article
The EMBO Journal, ISSN 0261-4189, 02/2011, Volume 30, Issue 4, pp. 770 - 782
Notch signalling is important for development and tissue homeostasis and activated in many human cancers. Nevertheless, mutations in Notch pathway components... 
miR‐200 | ZEB1 | EMT | Notch | stemness | miR-200 | STEM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | PHENOTYPE | E-CADHERIN | MIR-200 FAMILY | REPRESSORS ZEB1 | CELL BIOLOGY | EPITHELIAL-MESENCHYMAL TRANSITION | BREAST-CANCER | COLORECTAL-CANCER | Receptors, Notch - metabolism | Humans | Receptors, Notch - genetics | Gene Knockdown Techniques | Intercellular Signaling Peptides and Proteins - physiology | DNA-Binding Proteins - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Neoplasms - genetics | Membrane Proteins - physiology | Serrate-Jagged Proteins | Base Sequence | Membrane Proteins - metabolism | Nuclear Proteins - genetics | Jagged-1 Protein | Calcium-Binding Proteins - metabolism | Transcription Factors - physiology | DNA-Binding Proteins - antagonists & inhibitors | Membrane Proteins - genetics | Cells, Cultured | Intercellular Signaling Peptides and Proteins - genetics | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Signal Transduction - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | Transcription Factors - metabolism | Models, Biological | Calcium-Binding Proteins - physiology | Homeodomain Proteins - antagonists & inhibitors | Nuclear Proteins - antagonists & inhibitors | Signal Transduction - physiology | MicroRNAs - genetics | Feedback, Physiological - physiology | MicroRNAs - physiology | Homeodomain Proteins - physiology | Calcium-Binding Proteins - genetics | Zinc Finger E-box-Binding Homeobox 1 | Proteins | Signal transduction | Cellular biology | Molecular biology | Gene expression | Cancer | Index Medicus
Journal Article