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PLoS pathogens, ISSN 1553-7374, 2013, Volume 9, Issue 11, p. e1003773
Interferons (IFNs) are a group of cytokines with a well-established antiviral function. They can be induced by viral infection, are secreted and bind to... 
CELLS | DEFENSE | VIRUS-INFECTION | DISTINCT | RIG-I | MICROBIOLOGY | IRF-7 | ANTIVIRAL RESPONSE | VIROLOGY | GENE | SIGNALING PATHWAY | ADAPTER PROTEIN | PARASITOLOGY | Epithelial Cells - metabolism | Influenza A virus - genetics | Respiratory Mucosa - virology | Interferon Regulatory Factor-7 - genetics | Interferon Type I - immunology | Interferon Regulatory Factor-3 - genetics | Interleukins - metabolism | Orthomyxoviridae Infections - genetics | Respiratory Mucosa - pathology | Interleukins - genetics | Interleukins - immunology | Respiratory Mucosa - immunology | Adaptor Proteins, Signal Transducing - immunology | Interferon Type I - metabolism | Influenza A virus - immunology | Membrane Proteins - metabolism | Interferon Regulatory Factor-3 - immunology | Nerve Tissue Proteins - immunology | Membrane Proteins - genetics | Orthomyxoviridae Infections - metabolism | Epithelial Cells - pathology | Membrane Proteins - immunology | Interferon Regulatory Factor-7 - immunology | Interferon Regulatory Factor-7 - metabolism | Nerve Tissue Proteins - genetics | Mice, Knockout | Nerve Tissue Proteins - metabolism | Animals | Influenza A virus - metabolism | Epithelial Cells - immunology | Epithelial Cells - virology | Adaptor Proteins, Signal Transducing - genetics | Interferon Regulatory Factor-3 - metabolism | Interferon Type I - genetics | Mice | Respiratory Mucosa - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Orthomyxoviridae Infections - immunology | Epithelial cells | Influenza | Physiological aspects | Host-parasite relationships | Interferon | Genetic aspects | Genetic transcription | Research | Health aspects | Airway (Medicine) | Interleukins/metabolism | Nerve Tissue Proteins/immunology | Orthomyxoviridae Infections/genetics | Orthomyxoviridae Infections/metabolism | Membrane Proteins/genetics | Adaptor Proteins, Signal Transducing/genetics | Interferon Regulatory Factor-7/genetics | Interleukins/immunology | Membrane Proteins/immunology | Life Sciences | Orthomyxoviridae Infections/immunology | Influenza A virus/genetics | Nerve Tissue Proteins/metabolism | Respiratory Mucosa/immunology | Immunology | Interferon Type I/immunology | Epithelial Cells/immunology | Epithelial Cells/virology | Interferon Regulatory Factor-7/immunology | Epithelial Cells/metabolism | Interferon Regulatory Factor-3/immunology | Respiratory Mucosa/pathology | Influenza A virus/immunology | Interleukins/genetics | Interferon Regulatory Factor-3/genetics | Influenza A virus/metabolism | Adaptor Proteins, Signal Transducing/metabolism | Epithelial Cells/pathology | Adaptor Proteins, Signal Transducing/immunology | Interferon Type I/genetics | Interferon Regulatory Factor-3/metabolism | Membrane Proteins/metabolism | Nerve Tissue Proteins/genetics | Interferon Regulatory Factor-7/metabolism | Interferon Type I/metabolism | Respiratory Mucosa/metabolism | Respiratory Mucosa/virology | Cytokines | Genes | Rodents | Genomics | Genomes | Kinases | Experiments | Viral infections
Journal Article
Journal Article
Apoptosis (London), ISSN 1360-8185, 07/2017, Volume 22, Issue 7, pp. 920 - 932
.... Here, we report that RA/poly(I:C) co-treatment, synergically, induce the activation of Interferon Regulatory Factor-3 (IRF3... 
dsRNA | Breast cancer | TRAIL | Type-I IFNs | IRF3 | Retinoic acid | ACTIVATION | IRF-3 TRANSCRIPTION FACTOR | POSITIVE FEEDBACK | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOLLOW-UP | RANDOMIZED TRIAL | CELL BIOLOGY | PHASE-III TRIAL | LUNG-CANCER | DEATH LIGAND TRAIL | TOLL-LIKE RECEPTORS | INNATE IMMUNITY | Tretinoin - administration & dosage | RNA, Double-Stranded - administration & dosage | Apoptosis - drug effects | Humans | Apoptosis - genetics | Breast Neoplasms - drug therapy | Interferon Regulatory Factor-3 - genetics | Receptors, Tumor Necrosis Factor, Member 10c - genetics | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Cell Line, Tumor | Interferon Type I - genetics | Female | Receptors, TNF-Related Apoptosis-Inducing Ligand - genetics | Toll-Like Receptor 3 - genetics | Gene Expression Regulation, Neoplastic - drug effects | TNF-Related Apoptosis-Inducing Ligand - genetics | GPI-Linked Proteins - genetics | RNA | Cancer cells | Interferon | Biological response modifiers | Tretinoin | Apoptosis | Surgical implants | Correlation | Paracrine signalling | Activation | Caspase-3 | Anticancer properties | Receptors | Biomedical materials | Toll-like receptors | Biocompatibility | Inhibition | Autocrine signalling | Pathogens | Double-stranded RNA | Caspase | Poly (I:C) | Ribonucleic acid--RNA | TLR3 protein | Caspase-8 | Depletion | Interferon regulatory factor 3 | Antitumor activity | TRAIL protein | Interferon regulatory factor | Recognition | Cancer
Journal Article
Journal Article
Journal Article
Journal of Virology, ISSN 0022-538X, 08/2012, Volume 86, Issue 15, pp. 7728 - 7738
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
ANTIVIRAL RESPONSE | VIROLOGY | SUBTILASE SKI-1/S1P | GENE-EXPRESSION | BREAST-CANCER ONCOGENE | RIG-I | TANK-BINDING KINASE-1 | LYMPHOCYTIC CHORIOMENINGITIS VIRUS | NF-KAPPA-B | ADAPTER PROTEIN | VIRAL-INFECTION | Lymphocytic choriomeningitis virus - immunology | Humans | Immunity, Innate - genetics | Multiprotein Complexes - genetics | Lymphocytic Choriomeningitis - immunology | Lymphocytic choriomeningitis virus - metabolism | Interferon Regulatory Factor-3 - genetics | Sendai virus - metabolism | Lymphocytic Choriomeningitis - metabolism | Multiprotein Complexes - metabolism | Phosphorylation - genetics | I-kappa B Kinase - metabolism | Nucleocapsid Proteins - metabolism | HEK293 Cells | Phosphorylation - immunology | DEAD-box RNA Helicases - metabolism | Protein-Serine-Threonine Kinases - metabolism | Interferon Regulatory Factor-3 - immunology | Lymphocytic Choriomeningitis - genetics | DEAD Box Protein 58 | Mitochondrial Membranes - immunology | Sendai virus - immunology | Protein-Serine-Threonine Kinases - genetics | I-kappa B Kinase - genetics | Sendai virus - genetics | Mitochondrial Membranes - metabolism | DEAD-box RNA Helicases - genetics | Nucleocapsid Proteins - genetics | Cell Line, Tumor | DEAD-box RNA Helicases - immunology | Interferon Regulatory Factor-3 - metabolism | Lymphocytic choriomeningitis virus - genetics | I-kappa B Kinase - immunology | Nucleocapsid Proteins - immunology | Protein-Serine-Threonine Kinases - immunology | Multiprotein Complexes - immunology | Virus-Cell Interactions
Journal Article
PLoS pathogens, ISSN 1553-7374, 2013, Volume 9, Issue 1, p. e1003118
Journal Article