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PLoS pathogens, ISSN 1553-7374, 11/2013, Volume 9, Issue 11, pp. e1003773 - e1003773
Interferons (IFNs) are a group of cytokines with a well-established antiviral function. They can be induced by viral infection, are secreted and bind to... 
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | Epithelial Cells - metabolism | Influenza A virus - genetics | Respiratory Mucosa - virology | Interferon Regulatory Factor-7 - genetics | Interferon Type I - immunology | Interferon Regulatory Factor-3 - genetics | Interleukins - metabolism | Orthomyxoviridae Infections - genetics | Respiratory Mucosa - pathology | Interleukins - genetics | Interleukins - immunology | Respiratory Mucosa - immunology | Adaptor Proteins, Signal Transducing - immunology | Interferon Type I - metabolism | Influenza A virus - immunology | Membrane Proteins - metabolism | Interferon Regulatory Factor-3 - immunology | Nerve Tissue Proteins - immunology | Membrane Proteins - genetics | Orthomyxoviridae Infections - metabolism | Epithelial Cells - pathology | Membrane Proteins - immunology | Interferon Regulatory Factor-7 - immunology | Interferon Regulatory Factor-7 - metabolism | Nerve Tissue Proteins - genetics | Mice, Knockout | Nerve Tissue Proteins - metabolism | Animals | Influenza A virus - metabolism | Epithelial Cells - immunology | Epithelial Cells - virology | Adaptor Proteins, Signal Transducing - genetics | Interferon Regulatory Factor-3 - metabolism | Interferon Type I - genetics | Mice | Respiratory Mucosa - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Orthomyxoviridae Infections - immunology | Epithelial cells | Influenza | Physiological aspects | Host-parasite relationships | Interferon | Genetic aspects | Genetic transcription | Research | Health aspects | Airway (Medicine) | Index Medicus | Interleukins/metabolism | Nerve Tissue Proteins/immunology | Orthomyxoviridae Infections/genetics | Orthomyxoviridae Infections/metabolism | Membrane Proteins/genetics | Adaptor Proteins, Signal Transducing/genetics | Interferon Regulatory Factor-7/genetics | Interleukins/immunology | Membrane Proteins/immunology | Life Sciences | Orthomyxoviridae Infections/immunology | Influenza A virus/genetics | Nerve Tissue Proteins/metabolism | Respiratory Mucosa/immunology | Immunology | Interferon Type I/immunology | Epithelial Cells/immunology | Epithelial Cells/virology | Interferon Regulatory Factor-7/immunology | Epithelial Cells/metabolism | Interferon Regulatory Factor-3/immunology | Respiratory Mucosa/pathology | Influenza A virus/immunology | Interleukins/genetics | Interferon Regulatory Factor-3/genetics | Influenza A virus/metabolism | Adaptor Proteins, Signal Transducing/metabolism | Epithelial Cells/pathology | Adaptor Proteins, Signal Transducing/immunology | Interferon Type I/genetics | Interferon Regulatory Factor-3/metabolism | Membrane Proteins/metabolism | Nerve Tissue Proteins/genetics | Interferon Regulatory Factor-7/metabolism | Interferon Type I/metabolism | Respiratory Mucosa/metabolism | Respiratory Mucosa/virology | Cytokines | Genes | Rodents | Genomics | Genomes | Kinases | Experiments | Viral infections
Journal Article
American journal of physiology: endocrinology and metabolism, ISSN 0193-1849, 05/2013, Volume 305, Issue 4, pp. E485 - E495
.... In this study, we addressed the potential role of interferon regulatory factor 7 (IRF7), a master regulator of type I interferon-dependent immune responses, in the regulation of energy metabolism... 
Type 2 diabetes | Inflammation | Fatty liver | Adiposity | Endocrinology & Metabolism | Physiology | Life Sciences & Biomedicine | Science & Technology | Up-Regulation | Liver - pathology | Fatty Liver - pathology | Obesity - immunology | Diet, High-Fat - adverse effects | Male | Muscle, Skeletal - metabolism | Diabetes Mellitus, Type 2 - metabolism | Interferon Regulatory Factor-7 - genetics | Liver - immunology | Muscle, Skeletal - immunology | Diabetes Mellitus, Type 2 - immunology | Non-alcoholic Fatty Liver Disease | Diabetes Mellitus, Type 2 - etiology | Obesity - etiology | Weight Gain | Macrophages - immunology | Intra-Abdominal Fat - immunology | Fatty Liver - metabolism | Liver - metabolism | Mice, Inbred C57BL | Insulin Resistance | Random Allocation | Intra-Abdominal Fat - metabolism | Interferon Regulatory Factor-7 - metabolism | Mice, Knockout | Obesity - metabolism | Obesity - pathology | Animals | Interferon Regulatory Factor-7 - biosynthesis | Energy Metabolism | Endoplasmic Reticulum Stress | Fatty Liver - immunology | Mice, Obese | Mice | Diabetes Mellitus, Type 2 - pathology | Intra-Abdominal Fat - pathology | Muscle, Skeletal - pathology | Fatty Liver - etiology | Obesity | Pathogenesis | Insulin resistance | Lipids | Interferon | Diabetes | Metabolism | Index Medicus
Journal Article
Journal Article
Cell research, ISSN 1001-0602, 2013, Volume 23, Issue 12, pp. 1356 - 1368
...) region as well as T-cell defects in the thymus. Mechanistically, miR-142a-3p regulates HSC formation and differentiation through the repres sion of interferon regulatory factor 7 (irf... 
斑马鱼 | 调节因子 | 造血干细胞 | 脊椎动物 | microRNA | 遗传调控 | 转录因子 | Irf7 | Hematopoietic Stem Cell | Zebrafish | Mir-142A-3P | Mouse | Life Sciences & Biomedicine | Science & Technology | Cell Biology | MicroRNAs - antagonists & inhibitors | Humans | Embryo, Nonmammalian - metabolism | Oligonucleotides, Antisense - metabolism | MicroRNAs - metabolism | Interferon Regulatory Factor-7 - genetics | Embryo, Mammalian - metabolism | RNA Interference | T-Lymphocytes - metabolism | Gene Expression Regulation, Developmental | Base Sequence | HEK293 Cells | Cell Differentiation | 3' Untranslated Regions | Core Binding Factor Alpha 2 Subunit - metabolism | Animals, Genetically Modified | Core Binding Factor Alpha 2 Subunit - antagonists & inhibitors | Hematopoietic Stem Cells - metabolism | Interferon Regulatory Factor-7 - metabolism | Zebrafish - growth & development | Zebrafish - genetics | Animals | T-Lymphocytes - cytology | Hematopoietic Stem Cells - cytology | Interferon Regulatory Factor-7 - antagonists & inhibitors | Zebrafish - metabolism | T-Lymphocytes - immunology | Mice | MicroRNAs - genetics | Nitric Oxide - metabolism | Core Binding Factor Alpha 2 Subunit - genetics | Index Medicus | hematopoietic stem cell | mouse | miR-142a-3p | irf7 | zebrafish | Original
Journal Article
Journal Article