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Developmental Cell, ISSN 1534-5807, 10/2011, Volume 21, Issue 4, pp. 627 - 641
Morphogenesis of mammalian facial processes requires coordination of cellular proliferation, migration, and apoptosis to develop intricate features. Cleft lip... 
HOX | CLEFT-PALATE | LIP | MIDFACIAL MORPHOGENESIS | WNT9B | MICE | PROLIFERATION | DEVELOPMENTAL BIOLOGY | IRF6 | DIFFERENTIATION | EXPRESSION | CELL BIOLOGY | Cell Proliferation | Epithelial Cells - metabolism | Luciferases - metabolism | Cleft Lip - embryology | Humans | Interferon Regulatory Factors - metabolism | Molecular Sequence Data | Phosphoproteins - metabolism | Wnt Proteins - metabolism | Immunoenzyme Techniques | Wnt3 Protein - genetics | Transfection | Wnt Proteins - genetics | Chromatin Immunoprecipitation | Base Sequence | Trans-Activators - genetics | Wnt3 Protein - metabolism | Electrophoretic Mobility Shift Assay | Pre-B-Cell Leukemia Transcription Factor 1 | Transcription Factors - physiology | Mice, Inbred C57BL | RNA, Messenger - genetics | Cleft Palate - embryology | Interferon Regulatory Factors - genetics | Mice, Transgenic | Phosphoproteins - genetics | Cleft Lip - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Sequence Homology, Nucleic Acid | Blotting, Western | Mice, Knockout | Phenotype | Animals | Trans-Activators - metabolism | Cleft Palate - metabolism | Face - embryology | Mice | Homeodomain Proteins - physiology | Morphogenesis - physiology | Apoptosis | Proteins | Neurosciences | Developmental biology | Lubrication and lubricants | Analysis | Birth defects | Universities and colleges | Protein binding | Index Medicus | Lambdoidal Junction | Ectoderm | Wnt midfacial enhancer | Mouse | Pbx | Irf6 | Face | Wnt | p63
Journal Article
Blood, ISSN 0006-4971, 02/2013, Volume 121, Issue 9, pp. 1574 - 1583
Antiviral immunity and cross-presentation is mediated constitutively through CD8 alpha(+) and CD103(+) DCs. Development of these DC subsets is thought to... 
DENDRITIC CELL-POPULATIONS | LYMPHOID ORGANS | MOUSE | MONOCYTES | ANTIGEN PRESENTATION | INFECTION | HEMATOLOGY | EXPRESSION | T-CELLS | CROSS-PRESENTATION | CUTTING EDGE | Basic-Leucine Zipper Transcription Factors - metabolism | Dendritic Cells - immunology | Interferon Regulatory Factors - metabolism | Cell Survival - genetics | Dendritic Cells - physiology | Repressor Proteins - physiology | Cell Differentiation - genetics | Inhibitor of Differentiation Protein 2 - genetics | Interferon Regulatory Factors - physiology | Cross-Priming - genetics | Herpesvirus 1, Human - immunology | Dendritic Cells - metabolism | Repressor Proteins - metabolism | Transcription Factors - physiology | Cross-Priming - physiology | Mice, Inbred C57BL | Cells, Cultured | Interferon Regulatory Factors - genetics | Repressor Proteins - genetics | Mice, Transgenic | Basic-Leucine Zipper Transcription Factors - genetics | Transcription Factors - genetics | Cell Survival - immunology | Inhibitor of Differentiation Protein 2 - metabolism | Inhibitor of Differentiation Protein 2 - physiology | Transcription Factors - metabolism | Antigens, Viral - immunology | Basic-Leucine Zipper Transcription Factors - physiology | Cell Differentiation - immunology | CD8 Antigens - metabolism | Animals | Cross-Priming - immunology | Mice | Index Medicus | Abridged Index Medicus
Journal Article
Arthritis & Rheumatology, ISSN 2326-5191, 12/2015, Volume 67, Issue 12, pp. 3146 - 3157
Objective. Polymorphisms in the transcription factor interferon regulatory factor 5 (IRF5) are associated with an increased risk of developing rheumatoid... 
RHEUMATOID-ARTHRITIS | IMMUNE-COMPLEXES | SYSTEMIC-LUPUS | COLLAGEN-INDUCED ARTHRITIS | MURINE MODEL | K/BXN MOUSE | DENDRITIC CELLS | SYNOVIAL-FLUID | TOLL-LIKE RECEPTORS | RHEUMATOLOGY | AUTOIMMUNE-DISEASE | Arthritis, Experimental - genetics | Toll-Like Receptor 2 - genetics | Receptors, Interleukin-1 - genetics | Adaptor Proteins, Vesicular Transport - genetics | Synovial Fluid - metabolism | Interleukin-1beta - genetics | Gene Knockdown Techniques | Toll-Like Receptor 7 - immunology | Toll-Like Receptor 3 - genetics | Membrane Glycoproteins - immunology | Disease Models, Animal | Severity of Illness Index | Toll-Like Receptor 7 - genetics | Signal Transduction | Receptors, Interleukin-1 - immunology | Mice, Inbred C57BL | Interferon Regulatory Factors - genetics | Interleukin-1beta - immunology | Toll-Like Receptor 4 - genetics | Toll-Like Receptor 3 - immunology | Arthritis, Experimental - immunology | Toll-Like Receptor 4 - immunology | Adaptor Proteins, Vesicular Transport - immunology | Membrane Glycoproteins - genetics | Mice, Knockout | Synovial Fluid - immunology | Arthritis, Rheumatoid - genetics | Interferon Regulatory Factors - immunology | Animals | Myeloid Cells - metabolism | Toll-Like Receptor 2 - immunology | Mice | Arthritis, Rheumatoid - immunology | In Vitro Techniques | Arthritis | Cytokines | Genes | Rodents | Index Medicus | Abridged Index Medicus
Journal Article
British Journal of Haematology, ISSN 0007-1048, 08/2011, Volume 154, Issue 3, pp. 325 - 336
Overexpression of the transcription factor interferon regulatory factor‐4 (IRF4), which is common in multiple myeloma (MM), is associated with poor prognosis.... 
multiple myeloma | lenalidomide | prognostic markers | immunomodulatory | interferon regulatory factor‐4 | Interferon regulatory factor-4 | Prognostic markers | Immunomodulatory | Lenalidomide | Multiple myeloma | REFRACTORY MULTIPLE-MYELOMA | DRUG-RESISTANCE | KAPPA-B | MUM1/IRF4 EXPRESSION | THERAPY | PLUS DEXAMETHASONE | GENE-EXPRESSION | CHRONIC LYMPHOCYTIC-LEUKEMIA | SINGLE-AGENT LENALIDOMIDE | HEMATOLOGY | TRANSCRIPTION FACTOR | interferon regulatory factor-4 | Cell Proliferation | Prognosis | Humans | Interferon Regulatory Factors - antagonists & inhibitors | Middle Aged | Antineoplastic Agents - therapeutic use | Genes, myc | Thalidomide - pharmacology | Gene Knockdown Techniques | Dose-Response Relationship, Drug | Thalidomide - analogs & derivatives | Multiple Myeloma - drug therapy | Reverse Transcriptase Polymerase Chain Reaction - methods | Interferon Regulatory Factors - biosynthesis | Aged, 80 and over | Adult | Antineoplastic Agents - pharmacology | Retrospective Studies | Gene Expression Regulation, Neoplastic - drug effects | Tumor Cells, Cultured | Neoplasm Proteins - genetics | Neoplasm Proteins - biosynthesis | Interferon Regulatory Factors - genetics | Gene Expression Profiling - methods | Treatment Outcome | Down-Regulation - drug effects | Multiple Myeloma - metabolism | Multiple Myeloma - pathology | Aged | Biomarkers, Tumor - genetics | Thalidomide - therapeutic use | Biomarkers, Tumor - biosynthesis | Medical colleges | Analysis | Interferon | Angiogenesis inhibitors | Biological response modifiers | Index Medicus | Cell proliferation | Drugs | Transcription factors | Cell survival | Immunomodulation | biomarkers | Data processing | Myc protein | Cell death | Interferon regulatory factor 4 | Cell cycle | Bone marrow
Journal Article
Journal Article
by Duffy, David L and Zhu, Gu and Li, Xin and Sanna, Marianna and Iles, Mark M and Jacobs, Leonie C and Evans, David M and Yazar, Seyhan and Beesley, Jonathan and Law, Matthew H and Kraft, Peter and Visconti, Alessia and Taylor, John C and Lui, Fan and Wright, Margaret J and Henders, Anjali K and Bowdler, Lisa and Glass, Dan and Ikram, Arfan M and Uitterlinden, André G and Madden, Pamela A and Heath, Andrew C and Nelson, Elliot C and Green, Adele C and Chanock, Stephen and Barrett, Jennifer H and Brown, Matthew A and Hayward, Nicholas K and MacGregor, Stuart and Sturm, Richard A and Hewitt, Alex W and Lee, Jeffrey E and Brossard, Myriam and Moses, Eric K and Song, Fengju and Kumar, Rajiv and Easton, Douglas F and Pharoah, Paul D. P and Swerdlow, Anthony J and Kypreou, Katerina P and Harland, Mark and Randerson-Moor, Juliette and Akslen, Lars A and Andresen, Per A and Avril, Marie-Françoise and Azizi, Esther and Scarrà, Giovanna Bianchi and Brown, Kevin M and Dębniak, Tadeusz and Elder, David E and Fang, Shenying and Friedman, Eitan and Galan, Pilar and Ghiorzo, Paola and Gillanders, Elizabeth M and Goldstein, Alisa M and Gruis, Nelleke A and Hansson, Johan and Helsing, Per and Hočevar, Marko and Höiom, Veronica and Ingvar, Christian and Kanetsky, Peter A and Chen, Wei V and Landi, Maria Teresa and Lang, Julie and Lathrop, G. Mark and Lubiński, Jan and Mackie, Rona M and Mann, Graham J and Molven, Anders and Novaković, Srdjan and Olsson, Håkan and Puig, Susana and Puig-Butille, Joan Anton and Radford-Smith, Graham L and van der Stoep, Nienke and van Doorn, Remco and Whiteman, David C and Craig, Jamie E and Schadendorf, Dirk and Simms, Lisa A and Burdon, Kathryn P and Nyholt, Dale R and Pooley, Karen A and Orr, Nicholas and Stratigos, Alexander J and Cust, Anne E and Ward, Sarah V and Schulze, Hans-Joachim and Dunning, Alison M and Demenais, Florence and Amos, Christopher I and Kayser, Manfred and Hunter, David J and Newton Bishop, Julia A and Spector, Timothy D and Montgomery, Grant W and Mackey, David A and Smith, George Davey and ... and Melanoma GWAS Consortium
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 4774 - 10
Journal Article
Immunity, ISSN 1074-7613, 05/2015, Volume 42, Issue 5, pp. 916 - 928
Journal Article
Immunity, ISSN 1074-7613, 07/2017, Volume 47, Issue 1, pp. 135 - 147.e5
Lung infections cause prolonged immune alterations and elevated susceptibility to secondary pneumonia. We found that, after resolution of primary viral... 
interleukin 12 | mucosal immunology | Dendritic Cells | Natural Killer Cells | pneumonia | Bacterial Infection | Influenza Virus | Treg cells | Trauma | Transforming Growth Factor Beta | TGF-BETA | DENDRITIC CELLS | VENTILATOR-ASSOCIATED PNEUMONIA | INTENSIVE-CARE-UNIT | MACROPHAGES | IN-VIVO | REGULATORY T-CELLS | MICE | IMMUNOLOGY | EXPRESSION | CROSS-PRESENTATION | Dendritic Cells - immunology | Escherichia coli | Humans | Middle Aged | Interferon Regulatory Factors - metabolism | Male | T-Lymphocytes, Regulatory - immunology | Antigen Presentation | Pneumonia - immunology | Female | Influenza A virus - immunology | Cell Differentiation | Macrophages - immunology | Sepsis - immunology | Mice, Inbred C57BL | Cells, Cultured | Immune Tolerance | Interferon Regulatory Factors - genetics | Transcription Factors - genetics | Mice, Knockout | Transcription Factors - metabolism | Animals | Transforming Growth Factor beta - genetics | Escherichia coli Infections - immunology | Aged | Mice | Transforming Growth Factor beta - metabolism | Orthomyxoviridae Infections - immunology | Positive Regulatory Domain I-Binding Factor 1 | Antigens | Medical colleges | Pneumonia | Microbiology | Dendritic cells | Bacterial pneumonia | Disease susceptibility | Transforming growth factors | Macrophages | Influenza viruses | Killer cells | Interleukins | Influenza | Immunotherapy | Bone morphogenetic proteins | Health aspects | Intervention | Antigen presentation | Target recognition | Cytokines | Secretion | Lung | Infections | Lymphocytes T | Immunosuppression | E coli | Lungs | Immunogenicity | Lymphocytes | Interferon regulatory factor 4 | Rodents | Sepsis | Bacteria | Index Medicus
Journal Article