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PLoS pathogens, ISSN 1553-7374, 2013, Volume 9, Issue 11, p. e1003773
...) with antiviral function. Type I IFN has been known for more than half a century. However, more recently, type III IFN... 
CELLS | DEFENSE | VIRUS-INFECTION | DISTINCT | RIG-I | MICROBIOLOGY | IRF-7 | ANTIVIRAL RESPONSE | VIROLOGY | GENE | SIGNALING PATHWAY | ADAPTER PROTEIN | PARASITOLOGY | Epithelial Cells - metabolism | Influenza A virus - genetics | Respiratory Mucosa - virology | Interferon Regulatory Factor-7 - genetics | Interferon Type I - immunology | Interferon Regulatory Factor-3 - genetics | Interleukins - metabolism | Orthomyxoviridae Infections - genetics | Respiratory Mucosa - pathology | Interleukins - genetics | Interleukins - immunology | Respiratory Mucosa - immunology | Adaptor Proteins, Signal Transducing - immunology | Interferon Type I - metabolism | Influenza A virus - immunology | Membrane Proteins - metabolism | Interferon Regulatory Factor-3 - immunology | Nerve Tissue Proteins - immunology | Membrane Proteins - genetics | Orthomyxoviridae Infections - metabolism | Epithelial Cells - pathology | Membrane Proteins - immunology | Interferon Regulatory Factor-7 - immunology | Interferon Regulatory Factor-7 - metabolism | Nerve Tissue Proteins - genetics | Mice, Knockout | Nerve Tissue Proteins - metabolism | Animals | Influenza A virus - metabolism | Epithelial Cells - immunology | Epithelial Cells - virology | Adaptor Proteins, Signal Transducing - genetics | Interferon Regulatory Factor-3 - metabolism | Interferon Type I - genetics | Mice | Respiratory Mucosa - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Orthomyxoviridae Infections - immunology | Epithelial cells | Influenza | Physiological aspects | Host-parasite relationships | Interferon | Genetic aspects | Genetic transcription | Research | Health aspects | Airway (Medicine) | Interleukins/metabolism | Nerve Tissue Proteins/immunology | Orthomyxoviridae Infections/genetics | Orthomyxoviridae Infections/metabolism | Membrane Proteins/genetics | Adaptor Proteins, Signal Transducing/genetics | Interferon Regulatory Factor-7/genetics | Interleukins/immunology | Membrane Proteins/immunology | Life Sciences | Orthomyxoviridae Infections/immunology | Influenza A virus/genetics | Nerve Tissue Proteins/metabolism | Respiratory Mucosa/immunology | Immunology | Interferon Type I/immunology | Epithelial Cells/immunology | Epithelial Cells/virology | Interferon Regulatory Factor-7/immunology | Epithelial Cells/metabolism | Interferon Regulatory Factor-3/immunology | Respiratory Mucosa/pathology | Influenza A virus/immunology | Interleukins/genetics | Interferon Regulatory Factor-3/genetics | Influenza A virus/metabolism | Adaptor Proteins, Signal Transducing/metabolism | Epithelial Cells/pathology | Adaptor Proteins, Signal Transducing/immunology | Interferon Type I/genetics | Interferon Regulatory Factor-3/metabolism | Membrane Proteins/metabolism | Nerve Tissue Proteins/genetics | Interferon Regulatory Factor-7/metabolism | Interferon Type I/metabolism | Respiratory Mucosa/metabolism | Respiratory Mucosa/virology | Cytokines | Genes | Rodents | Genomics | Genomes | Kinases | Experiments | Viral infections
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2013, Volume 339, Issue 6126, pp. 1448 - 1453
Type I interferons (IFN-α and IFN-β) are important for protection against many viral infections, whereas type II interferon (IFN-γ... 
Monocytes | Messenger RNA | Tuberculosis | Mycobacterium tuberculosis | Antimicrobials | REPORTS | Leprosy | Infections | Skin | Lesions | Gene expression | LISTERIA-MONOCYTOGENES | ACTIVATION | PROFILES | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | HUMAN TUBERCULOSIS | IL-1-BETA | INDUCTION | DEPENDENT ANTIMICROBIAL PATHWAY | SARCOIDOSIS | LEPROSY | Up-Regulation | Interferon-beta - immunology | Humans | Transcriptome | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - genetics | Monocytes - metabolism | Monocytes - immunology | Interferon-gamma - metabolism | Antimicrobial Cationic Peptides - metabolism | RNA, Messenger - metabolism | Receptors, Calcitriol - genetics | Mycobacterium leprae - immunology | Interferon-beta - genetics | Interleukin-10 - metabolism | beta-Defensins - metabolism | Interferon-gamma - genetics | Antimicrobial Cationic Peptides - genetics | Leprosy, Lepromatous - genetics | Mycobacterium leprae - physiology | Leprosy, Tuberculoid - immunology | beta-Defensins - genetics | Leprosy, Lepromatous - immunology | RNA, Messenger - genetics | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - metabolism | Microbial Viability | Receptors, Calcitriol - metabolism | Leprosy, Tuberculoid - genetics | Tuberculosis - immunology | Leprosy, Lepromatous - metabolism | Interferon-beta - metabolism | Tuberculosis - genetics | Leprosy, Tuberculoid - metabolism | Interferon-gamma - immunology | Interleukin-10 - genetics | Interleukins | Physiological aspects | Host-parasite relationships | Anti-infective agents | Interferon | Genetic aspects | Health aspects | Antimicrobial agents | Pathogenesis | Genes | Bacteria | Human behavior | Antiinfectives and antibacterials | Digital signatures
Journal Article
Pediatric rheumatology online journal, ISSN 1546-0096, 2016, Volume 14, Issue 1, p. 35
Defective regulation of type I interferon response is associated with severe inflammatory phenotypes and autoimmunity... 
CANDLE | Type I interferonopathies | Familial lupus | Type I interferon | Aicardi-Goutières syndrome | SAVI | ALPHA MONOCLONAL-ANTIBODY | SYSTEMIC-LUPUS-ERYTHEMATOSUS | HYPER-GAMMA-GLOBULINEMIA | RHEUMATOLOGY | MUSCULAR-ATROPHY | AICARDI-GOUTIERES-SYNDROME | FAMILIAL CHILBLAIN LUPUS | Aicardi-Goutieres syndrome | DNA EXONUCLEASE TREX1 | PROTEASOME SUBUNIT | PEDIATRICS | PHASE-I | IFN-ALPHA | Proteome - genetics | Nervous System Malformations - immunology | Rare Diseases - immunology | Humans | Vascular Calcification - genetics | Rare Diseases - diagnosis | Arthritis, Juvenile - diagnosis | Metacarpus - abnormalities | Interferon Type I - immunology | Mutation - immunology | Autoimmune Diseases - genetics | Osteochondrodysplasias - genetics | Proteome - immunology | Lupus Erythematosus, Systemic - immunology | Osteoporosis - genetics | Autoimmune Diseases of the Nervous System - diagnosis | Metacarpus - immunology | Osteochondrodysplasias - immunology | Osteoporosis - immunology | Signal Transduction | Vascular Calcification - immunology | Aortic Diseases - immunology | Autoimmune Diseases - immunology | Autoimmune Diseases - diagnosis | Mutation - genetics | Odontodysplasia - immunology | Lupus Erythematosus, Systemic - diagnosis | Autoimmune Diseases of the Nervous System - immunology | Dental Enamel Hypoplasia - immunology | Homozygote | Aortic Diseases - genetics | Muscular Diseases - immunology | Rare Diseases - therapy | Arthritis, Juvenile - immunology | Lupus Erythematosus, Systemic - genetics | Nervous System Malformations - diagnosis | Autoimmune Diseases - therapy | Interferon Type I - genetics | Odontodysplasia - genetics | Muscular Diseases - genetics | Dental Enamel Hypoplasia - genetics | Systemic lupus erythematosus | Rheumatic diseases | Practice | Interferon | Research | Children | Rheumatologists | Health aspects | Risk factors
Journal Article
Journal of virology, ISSN 1098-5514, 2018, Volume 92, Issue 6
Journal Article
Nature (London), ISSN 1476-4687, 2010, Volume 467, Issue 7314, pp. 460 - 464
Journal Article
PLoS genetics, ISSN 1553-7404, 2010, Volume 6, Issue 2, p. e1000841
Journal Article
PLoS pathogens, ISSN 1553-7374, 2014, Volume 10, Issue 4, p. e1003989
.... In this study, using murine bone marrow-derived dendritic cells, we assessed type I interferon (IFN... 
DOUBLE-STRANDED-RNA | CYCLIC GMP-AMP | KAPPA-B KINASE | COMPLEX CLASS-II | DEPENDENT PROTEIN-KINASE | MICROBIOLOGY | ANTIGEN PRESENTATION | INTERFERON INDUCTION | INTRACELLULAR DNA | VIROLOGY | TOLL-LIKE RECEPTORS | INNATE IMMUNE SENSOR | PARASITOLOGY | Dendritic Cells - immunology | Lysosomes - genetics | Immunity, Innate - genetics | Vaccinia virus - genetics | Viral Proteins - metabolism | Endosomes - metabolism | Bone Marrow Cells - virology | Phosphorylation - genetics | Bone Marrow Cells - immunology | Interferon-beta - genetics | Phosphorylation - immunology | Receptor, Interferon alpha-beta - genetics | Nucleotidyltransferases - metabolism | Vaccinia - metabolism | Protein-Serine-Threonine Kinases - metabolism | Receptor, Interferon alpha-beta - metabolism | Endosomes - genetics | Membrane Proteins - genetics | RNA-Binding Proteins - immunology | Viral Proteins - genetics | Mice, Knockout | Interferon-beta - metabolism | Receptor, Interferon alpha-beta - immunology | Vaccinia - immunology | Virulence Factors - metabolism | Mice | Lysosomes - immunology | RNA-Binding Proteins - metabolism | Endosomes - immunology | RNA-Binding Proteins - genetics | Interferon-beta - immunology | Virulence Factors - genetics | Viral Proteins - immunology | Virulence Factors - immunology | Interferon Regulatory Factor-3 - genetics | Vaccinia virus - immunology | Lysosomes - metabolism | Female | Membrane Proteins - metabolism | Dendritic Cells - virology | Dendritic Cells - metabolism | Interferon Regulatory Factor-3 - immunology | Vaccinia virus - metabolism | Protein-Serine-Threonine Kinases - genetics | Membrane Proteins - immunology | Vaccinia - genetics | Animals | Interferon Regulatory Factor-3 - metabolism | Nucleotidyltransferases - genetics | Protein-Serine-Threonine Kinases - immunology | Nucleotidyltransferases - immunology | Bone Marrow Cells - metabolism | Microbiological research | Dendritic cells | Genetic research | Genetic aspects | Research | Nucleotide sequencing | Vaccinia | Health aspects | DNA sequencing | Proteins | Studies | Smallpox | Transcription factors | Genes | Deoxyribonucleic acid | DNA | Infections | Genomes | Vaccines | Viral infections | Immune system
Journal Article
Arthritis & rheumatology (Hoboken, N.J.), ISSN 2326-5191, 2017, Volume 69, Issue 10, pp. 2081 - 2091
Journal Article
Nature genetics, ISSN 1546-1718, 2012, Volume 44, Issue 11, pp. 1243 - 1248
Journal Article