X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (53018) 53018
Newsletter (199) 199
Newspaper Article (83) 83
Book Chapter (54) 54
Publication (16) 16
Magazine Article (11) 11
Transcript (10) 10
Conference Proceeding (9) 9
Dissertation (9) 9
Book / eBook (6) 6
Government Document (2) 2
Streaming Video (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (32165) 32165
animals (28929) 28929
mice (19791) 19791
immunology (17498) 17498
female (15085) 15085
interferon (13641) 13641
male (12490) 12490
interferon-gamma (9242) 9242
cytokines (8835) 8835
expression (8438) 8438
cells, cultured (8382) 8382
interferon-gamma - metabolism (7559) 7559
mice, inbred c57bl (7297) 7297
inflammation (7085) 7085
cell biology (6739) 6739
adult (6632) 6632
gene expression (6387) 6387
activation (6242) 6242
cell line (5986) 5986
middle aged (5949) 5949
biochemistry & molecular biology (5778) 5778
signal transduction (5603) 5603
research article (5572) 5572
proteins (5559) 5559
biological response modifiers (5300) 5300
dendritic cells (5207) 5207
research (4939) 4939
health aspects (4937) 4937
lymphocytes (4851) 4851
multidisciplinary sciences (4839) 4839
mice, knockout (4766) 4766
analysis (4481) 4481
interferon-gamma - pharmacology (4406) 4406
medicine (4326) 4326
t cells (4305) 4305
cytokines - metabolism (4294) 4294
ifn-gamma (4250) 4250
immune response (4228) 4228
viruses (4211) 4211
infection (4201) 4201
apoptosis (4178) 4178
infections (4093) 4093
immune system (4055) 4055
mice, inbred balb c (4005) 4005
virology (3985) 3985
cells (3982) 3982
t-cells (3944) 3944
gene-expression (3748) 3748
macrophages (3748) 3748
flow cytometry (3722) 3722
oncology (3692) 3692
science (3513) 3513
immunity (3512) 3512
lymphocytes t (3506) 3506
cancer (3401) 3401
interferon-gamma - biosynthesis (3371) 3371
microbiology (3354) 3354
aged (3340) 3340
infectious diseases (3268) 3268
disease models, animal (3193) 3193
nf-kappa-b (3102) 3102
rna, messenger - metabolism (3092) 3092
biology (3057) 3057
medicine, research & experimental (3045) 3045
induction (3031) 3031
γ-interferon (3009) 3009
cell line, tumor (2913) 2913
physiological aspects (2900) 2900
phosphorylation (2836) 2836
rats (2816) 2816
rodents (2789) 2789
innate immunity (2781) 2781
t-lymphocytes - immunology (2781) 2781
genetic aspects (2779) 2779
antigens (2763) 2763
genes (2693) 2693
enzyme-linked immunosorbent assay (2653) 2653
in-vivo (2621) 2621
dendritic cells - immunology (2594) 2594
disease (2582) 2582
gene expression regulation (2546) 2546
virus diseases (2540) 2540
interferon-gamma - immunology (2518) 2518
rna (2438) 2438
interferon-gamma - genetics (2389) 2389
tumor necrosis factor-alpha - metabolism (2313) 2313
macrophages - metabolism (2311) 2311
molecular sequence data (2288) 2288
rna, messenger - genetics (2248) 2248
time factors (2236) 2236
neurosciences (2235) 2235
pathogenesis (2231) 2231
immunotherapy (2225) 2225
cd4-positive t-lymphocytes - immunology (2219) 2219
reverse transcriptase polymerase chain reaction (2196) 2196
responses (2174) 2174
tumor-necrosis-factor (2174) 2174
cell proliferation (2173) 2173
interferon type i - metabolism (2151) 2151
interferon-alpha (2125) 2125
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (53162) 53162
Japanese (245) 245
Russian (115) 115
Chinese (106) 106
French (31) 31
Polish (18) 18
German (16) 16
Spanish (12) 12
Italian (9) 9
Czech (4) 4
Hungarian (4) 4
Turkish (4) 4
Arabic (2) 2
Danish (2) 2
Ukrainian (2) 2
Dutch (1) 1
Portuguese (1) 1
Slovak (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


PLoS pathogens, ISSN 1553-7374, 2013, Volume 9, Issue 11, p. e1003773
...) with antiviral function. Type I IFN has been known for more than half a century. However, more recently, type III IFN... 
CELLS | DEFENSE | VIRUS-INFECTION | DISTINCT | RIG-I | MICROBIOLOGY | IRF-7 | ANTIVIRAL RESPONSE | VIROLOGY | GENE | SIGNALING PATHWAY | ADAPTER PROTEIN | PARASITOLOGY | Epithelial Cells - metabolism | Influenza A virus - genetics | Respiratory Mucosa - virology | Interferon Regulatory Factor-7 - genetics | Interferon Type I - immunology | Interferon Regulatory Factor-3 - genetics | Interleukins - metabolism | Orthomyxoviridae Infections - genetics | Respiratory Mucosa - pathology | Interleukins - genetics | Interleukins - immunology | Respiratory Mucosa - immunology | Adaptor Proteins, Signal Transducing - immunology | Interferon Type I - metabolism | Influenza A virus - immunology | Membrane Proteins - metabolism | Interferon Regulatory Factor-3 - immunology | Nerve Tissue Proteins - immunology | Membrane Proteins - genetics | Orthomyxoviridae Infections - metabolism | Epithelial Cells - pathology | Membrane Proteins - immunology | Interferon Regulatory Factor-7 - immunology | Interferon Regulatory Factor-7 - metabolism | Nerve Tissue Proteins - genetics | Mice, Knockout | Nerve Tissue Proteins - metabolism | Animals | Influenza A virus - metabolism | Epithelial Cells - immunology | Epithelial Cells - virology | Adaptor Proteins, Signal Transducing - genetics | Interferon Regulatory Factor-3 - metabolism | Interferon Type I - genetics | Mice | Respiratory Mucosa - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Orthomyxoviridae Infections - immunology | Epithelial cells | Influenza | Physiological aspects | Host-parasite relationships | Interferon | Genetic aspects | Genetic transcription | Research | Health aspects | Airway (Medicine) | Interleukins/metabolism | Nerve Tissue Proteins/immunology | Orthomyxoviridae Infections/genetics | Orthomyxoviridae Infections/metabolism | Membrane Proteins/genetics | Adaptor Proteins, Signal Transducing/genetics | Interferon Regulatory Factor-7/genetics | Interleukins/immunology | Membrane Proteins/immunology | Life Sciences | Orthomyxoviridae Infections/immunology | Influenza A virus/genetics | Nerve Tissue Proteins/metabolism | Respiratory Mucosa/immunology | Immunology | Interferon Type I/immunology | Epithelial Cells/immunology | Epithelial Cells/virology | Interferon Regulatory Factor-7/immunology | Epithelial Cells/metabolism | Interferon Regulatory Factor-3/immunology | Respiratory Mucosa/pathology | Influenza A virus/immunology | Interleukins/genetics | Interferon Regulatory Factor-3/genetics | Influenza A virus/metabolism | Adaptor Proteins, Signal Transducing/metabolism | Epithelial Cells/pathology | Adaptor Proteins, Signal Transducing/immunology | Interferon Type I/genetics | Interferon Regulatory Factor-3/metabolism | Membrane Proteins/metabolism | Nerve Tissue Proteins/genetics | Interferon Regulatory Factor-7/metabolism | Interferon Type I/metabolism | Respiratory Mucosa/metabolism | Respiratory Mucosa/virology | Cytokines | Genes | Rodents | Genomics | Genomes | Kinases | Experiments | Viral infections
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2013, Volume 339, Issue 6126, pp. 1448 - 1453
Type I interferons (IFN-α and IFN-β) are important for protection against many viral infections, whereas type II interferon (IFN-γ... 
Monocytes | Messenger RNA | Tuberculosis | Mycobacterium tuberculosis | Antimicrobials | REPORTS | Leprosy | Infections | Skin | Lesions | Gene expression | LISTERIA-MONOCYTOGENES | ACTIVATION | PROFILES | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | HUMAN TUBERCULOSIS | IL-1-BETA | INDUCTION | DEPENDENT ANTIMICROBIAL PATHWAY | SARCOIDOSIS | LEPROSY | Up-Regulation | Interferon-beta - immunology | Humans | Transcriptome | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - genetics | Monocytes - metabolism | Monocytes - immunology | Interferon-gamma - metabolism | Antimicrobial Cationic Peptides - metabolism | RNA, Messenger - metabolism | Receptors, Calcitriol - genetics | Mycobacterium leprae - immunology | Interferon-beta - genetics | Interleukin-10 - metabolism | beta-Defensins - metabolism | Interferon-gamma - genetics | Antimicrobial Cationic Peptides - genetics | Leprosy, Lepromatous - genetics | Mycobacterium leprae - physiology | Leprosy, Tuberculoid - immunology | beta-Defensins - genetics | Leprosy, Lepromatous - immunology | RNA, Messenger - genetics | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - metabolism | Microbial Viability | Receptors, Calcitriol - metabolism | Leprosy, Tuberculoid - genetics | Tuberculosis - immunology | Leprosy, Lepromatous - metabolism | Interferon-beta - metabolism | Tuberculosis - genetics | Leprosy, Tuberculoid - metabolism | Interferon-gamma - immunology | Interleukin-10 - genetics | Interleukins | Physiological aspects | Host-parasite relationships | Anti-infective agents | Interferon | Genetic aspects | Health aspects | Antimicrobial agents | Pathogenesis | Genes | Bacteria | Human behavior | Antiinfectives and antibacterials | Digital signatures
Journal Article
Diabetes care, ISSN 1935-5548, 2010, Volume 33, Issue 4, pp. 861 - 868
Journal Article
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 2016, Volume 44, Issue 6, pp. 1325 - 1336
Journal Article
PLoS pathogens, ISSN 1553-7374, 2013, Volume 9, Issue 4, p. e1003256
.... RIG-I had the strongest effect through a MAVS/TRIM25/Riplet-dependent type I IFN signaling pathway upstream of TLR3 and NLRP3... 
INTERLEUKIN-1 | RNA | RESPIRATORY VIRAL-INFECTION | INNATE IMMUNE-RESPONSE | RIG-I | MICROBIOLOGY | INDUCTION | NS1 PROTEIN | ANTIVIRAL RESPONSES | INTERFERON | VIROLOGY | EPITHELIAL-CELLS | PARASITOLOGY | Epithelial Cells - metabolism | Inflammasomes - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Caspase 1 - metabolism | Male | Tripartite Motif Proteins | Lung - virology | RNA Interference | Respiratory Mucosa - immunology | HEK293 Cells | Cytoskeletal Proteins - metabolism | Lung - metabolism | Toll-Like Receptor 3 - genetics | DEAD-box RNA Helicases - metabolism | Influenza A Virus, H1N1 Subtype - metabolism | Macrophages - immunology | DEAD Box Protein 58 | Respiratory Mucosa - cytology | Signal Transduction | Cells, Cultured | Ubiquitin-Protein Ligases - metabolism | Ferrets | Toll-Like Receptor 3 - metabolism | Transcription Factors - metabolism | Carrier Proteins - genetics | DEAD-box RNA Helicases - genetics | Animals | Carrier Proteins - metabolism | Interferon-beta - metabolism | Caspase 1 - genetics | CARD Signaling Adaptor Proteins | Viral Nonstructural Proteins - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Cytoskeletal Proteins | Toll-Like Receptor 3 | Interferon-beta | Lung | Macrophages | Life Sciences | Influenza A Virus, H1N1 Subtype | Caspase 1 | Carrier Proteins | Viral Nonstructural Proteins | DEAD-box RNA Helicases | Inflammasomes | Respiratory Mucosa | Epithelial Cells | Virology | Ubiquitin-Protein Ligases | Microbiology and Parasitology | Adaptor Proteins, Signal Transducing | Transcription Factors | Proteins | Medical research | Experiments | Respiratory diseases | Influenza
Journal Article
Arthritis research & therapy, ISSN 1478-6354, 2013, Volume 15, Issue 5, pp. R151 - R151
...)-1, tissue inhibitor of metalloproteinase (TIMP)-1, MMP-2 and type-I collagen was quantified by enzyme-linked immunosorbent assay (ELISA... 
RHEUMATOID-ARTHRITIS | MATRIX METALLOPROTEINASES | SYNOVIAL FIBROBLASTS | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | GENE-EXPRESSION | SKIN FIBROSIS | NECROSIS-FACTOR-ALPHA | RHEUMATOLOGY | NF-KAPPA-B | T-CELLS | PULMONARY-FIBROSIS | Interleukin-8 - genetics | Gene Expression - drug effects | Skin - metabolism | Humans | Scleroderma, Systemic - pathology | Culture Media, Conditioned - pharmacology | Male | Interleukin-17 - pharmacology | Dose-Response Relationship, Drug | Collagen Type I - genetics | Th17 Cells - metabolism | Radioimmunoassay | Inflammation Mediators - metabolism | Female | Chemokine CCL2 - metabolism | Interleukin-8 - metabolism | Matrix Metalloproteinase 1 - genetics | Skin - pathology | Fibroblasts - metabolism | Collagen Type I - metabolism | Enzyme-Linked Immunosorbent Assay | Scleroderma, Systemic - metabolism | Cells, Cultured | Scleroderma, Systemic - genetics | Chemokine CCL2 - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Tumor Necrosis Factor-alpha - pharmacology | Fibroblasts - drug effects | Matrix Metalloproteinase 1 - metabolism | Interferon-gamma - pharmacology | Culture Media, Conditioned - metabolism | Proteins | Medical equipment and supplies industry | Interleukins | Systemic scleroderma | Medical test kit industry | Scleroderma (Disease) | High-definition television | Skin | Biological response modifiers | Enzyme-linked immunosorbent assay
Journal Article
Nature (London), ISSN 1476-4687, 2009, Volume 461, Issue 7265, pp. 788 - 792
The innate immune system is critical for the early detection of invading pathogens and for initiating cellular host defence countermeasures, which include the production of type I interferon (IFN) 1-3... 
ACTIVATION | HEPATITIS-C VIRUS | RECOGNITION | RNA | MULTIDISCIPLINARY SCIENCES | INFLAMMASOME | RIG-I | CYTOSOLIC DNA | KAPPA-B | ADAPTER PROTEIN | CYTOPLASMIC DNA | DNA, Bacterial - metabolism | Vesicular Transport Proteins - metabolism | Vaccines, DNA - immunology | Endoplasmic Reticulum - metabolism | DNA, Bacterial - immunology | Antigen-Presenting Cells - microbiology | Listeria monocytogenes - immunology | Interferon Type I - immunology | Interferon Type I - biosynthesis | Membrane Proteins - deficiency | Cytoplasmic Vesicles - metabolism | Plasmids - genetics | Herpesvirus 1, Human - immunology | Membrane Proteins - metabolism | Fibroblasts - microbiology | Protein-Serine-Threonine Kinases - metabolism | Fibroblasts - metabolism | Fibroblasts - virology | T-Lymphocytes, Cytotoxic - immunology | Antigen-Presenting Cells - metabolism | Intracellular Space - immunology | Membrane Proteins - genetics | Plasmids - immunology | DNA, Viral - metabolism | Antigen-Presenting Cells - immunology | Antigen-Presenting Cells - virology | Mice, Knockout | Protein Transport | DNA, Viral - immunology | Immunity, Innate - immunology | Animals | Intracellular Space - metabolism | Listeria monocytogenes - genetics | Fibroblasts - immunology | Herpesvirus 1, Human - genetics | Mice | Herpesvirus 1, Human - pathogenicity | Physiological aspects | Genetic aspects | Interferon | Immunity | Proteins | Viruses | Immunization | E coli | Research & development--R&D | Cells
Journal Article
PLoS pathogens, ISSN 1553-7374, 2014, Volume 10, Issue 4, p. e1003989
.... In this study, using murine bone marrow-derived dendritic cells, we assessed type I interferon (IFN... 
DOUBLE-STRANDED-RNA | CYCLIC GMP-AMP | KAPPA-B KINASE | COMPLEX CLASS-II | DEPENDENT PROTEIN-KINASE | MICROBIOLOGY | ANTIGEN PRESENTATION | INTERFERON INDUCTION | INTRACELLULAR DNA | VIROLOGY | TOLL-LIKE RECEPTORS | INNATE IMMUNE SENSOR | PARASITOLOGY | Dendritic Cells - immunology | Lysosomes - genetics | Immunity, Innate - genetics | Vaccinia virus - genetics | Viral Proteins - metabolism | Endosomes - metabolism | Bone Marrow Cells - virology | Phosphorylation - genetics | Bone Marrow Cells - immunology | Interferon-beta - genetics | Phosphorylation - immunology | Receptor, Interferon alpha-beta - genetics | Nucleotidyltransferases - metabolism | Vaccinia - metabolism | Protein-Serine-Threonine Kinases - metabolism | Receptor, Interferon alpha-beta - metabolism | Endosomes - genetics | Membrane Proteins - genetics | RNA-Binding Proteins - immunology | Viral Proteins - genetics | Mice, Knockout | Interferon-beta - metabolism | Receptor, Interferon alpha-beta - immunology | Vaccinia - immunology | Virulence Factors - metabolism | Mice | Lysosomes - immunology | RNA-Binding Proteins - metabolism | Endosomes - immunology | RNA-Binding Proteins - genetics | Interferon-beta - immunology | Virulence Factors - genetics | Viral Proteins - immunology | Virulence Factors - immunology | Interferon Regulatory Factor-3 - genetics | Vaccinia virus - immunology | Lysosomes - metabolism | Female | Membrane Proteins - metabolism | Dendritic Cells - virology | Dendritic Cells - metabolism | Interferon Regulatory Factor-3 - immunology | Vaccinia virus - metabolism | Protein-Serine-Threonine Kinases - genetics | Membrane Proteins - immunology | Vaccinia - genetics | Animals | Interferon Regulatory Factor-3 - metabolism | Nucleotidyltransferases - genetics | Protein-Serine-Threonine Kinases - immunology | Nucleotidyltransferases - immunology | Bone Marrow Cells - metabolism | Microbiological research | Dendritic cells | Genetic research | Genetic aspects | Research | Nucleotide sequencing | Vaccinia | Health aspects | DNA sequencing | Proteins | Studies | Smallpox | Transcription factors | Genes | Deoxyribonucleic acid | DNA | Infections | Genomes | Vaccines | Viral infections | Immune system
Journal Article
Journal Article