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1. Full Text Interferon alpha (IFNα)-induced TRIM22 interrupts HCV replication by ubiquitinating NS5A
by Yang, Chen and Zhao, Xinhao and Sun, Dakang and Yang, Leilei and Chong, Chang and Pan, Yu and Chi, Xiumei and Gao, Yanhang and Wang, Moli and Shi, Xiaodong and Sun, Haibo and Lv, Juan and Gao, Yuanda and Zhong, Jin and Niu, Junqi and Sun, Bing
Cellular & molecular immunology, ISSN 1672-7681, 01/2016, Volume 13, Issue 1, pp. 94 - 102
IFNα | HCV | NS5A | TRIM22 | ubiquitin | Life Sciences & Biomedicine | Immunology | Science & Technology | RNA, Small Interfering - genetics | Hepatitis C, Chronic - pathology | Hepacivirus - immunology | Minor Histocompatibility Antigens | Humans | Hepatitis C, Chronic - virology | Repressor Proteins - antagonists & inhibitors | Viral Load | Tripartite Motif Proteins | Proteolysis - drug effects | Ubiquitination - drug effects | Interferon-alpha - genetics | HEK293 Cells | Hepatocytes - drug effects | Viral Nonstructural Proteins - immunology | Hepacivirus - drug effects | Virus Replication - drug effects | Signal Transduction | Gene Expression Regulation | Interferon-alpha - therapeutic use | Repressor Proteins - genetics | Viral Nonstructural Proteins - genetics | Repressor Proteins - agonists | Hepatitis C, Chronic - drug therapy | Hepatocytes - immunology | Interferon-alpha - immunology | Host-Pathogen Interactions | Repressor Proteins - immunology | Hepatitis C, Chronic - immunology | Cell Line, Tumor | Hepatocytes - virology | Hepacivirus - growth & development | RNA, Small Interfering - metabolism | Index Medicus
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2. Full Text Comparative effectiveness and safety of ribavirin plus interferon-alpha, lopinavir/ritonavir plus interferon-alpha, and ribavirin plus lopinavir/ritonavir plus interferon-alpha in patients with mild to moderate novel coronavirus disease 2019: Study protocol
by Zeng, Yan-Ming and Xu, Xiao-Lei and He, Xiao-Qing and Tang, Sheng-Quan and Li, Yao and Huang, Yin-Qiu and Harypursat, Vijay and Chen, Yao-Kai
Chinese medical journal, ISSN 0366-6999, 2020, Volume 133, Issue 9, pp. 1132 - 1134
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Pandemics | Ritonavir - administration & dosage | Coronavirus Infections - drug therapy | Humans | Middle Aged | Pneumonia, Viral - drug therapy | Antiviral Agents - administration & dosage | Randomized Controlled Trials as Topic | COVID-19 | Interferon-alpha - administration & dosage | SARS-CoV-2 | Ribavirin - administration & dosage | Betacoronavirus | Lopinavir - administration & dosage | Adult | Aged | Drug Therapy, Combination | Interferon | Coronaviruses | Middle East respiratory syndrome | Index Medicus | Correspondence
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3. Full Text Interferon Alpha Enhances NK Cell Function and the Suppressive Capacity of HIV-Specific CD8+ T Cells
by Kwaa, Abena K R and Talana, Chloe A G and Blankson, Joel N
Journal of virology, ISSN 0022-538X, 02/2019, Volume 93, Issue 3
HIV-1 | NK cells | interferon alpha | CD cells | Life Sciences & Biomedicine | Science & Technology | Virology | Interferon-alpha - pharmacology | Antiviral Agents - pharmacology | Cytokines - metabolism | HIV Seropositivity | HIV-1 - drug effects | Killer Cells, Natural - virology | Lymphocyte Activation | HIV Infections - virology | Humans | Viremia - drug therapy | Virus Latency - drug effects | Case-Control Studies | HIV Infections - immunology | HIV-1 - immunology | Viremia - virology | CD8-Positive T-Lymphocytes - virology | CD8-Positive T-Lymphocytes - drug effects | Killer Cells, Natural - immunology | HIV Infections - drug therapy | Viremia - immunology | Killer Cells, Natural - drug effects | CD8-Positive T-Lymphocytes - immunology | Virus Latency - immunology | Cell Degranulation - drug effects | Index Medicus
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4. Full Text I kappa B kinase alpha (IKKα) activity is required for functional maturation of dendritic cells and acquired immunity to infection
by Mancino, Alessandra and Habbeddine, Mohamed and Johnson, Ella and Luron, Lionel and Bebien, Magali and Memet, Sylvie and Fong, Carol and Bajenoff, Marc and Wu, Xuefeng and Karin, Michael and Caamano, Jorge and Chi, Hongbo and Seed, Michael and Lawrence, Toby
The EMBO journal, ISSN 0261-4189, 03/2013, Volume 32, Issue 6, pp. 816 - 828
interferon regulatory factor 3 | dendritic cells | I kappa B Kinase alpha | T‐cell priming | T-cell priming | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Dendritic Cells - immunology | Humans | Dendritic Cells - physiology | Listeria monocytogenes - immunology | I-kappa B Kinase - physiology | Adaptive Immunity - genetics | Cell Differentiation - genetics | I-kappa B Kinase - metabolism | Listeriosis - immunology | Dendritic Cells - metabolism | Infection - immunology | Listeriosis - genetics | Mice, Inbred C57BL | Cells, Cultured | Mice, Transgenic | Inflammation - immunology | I-kappa B Kinase - genetics | Cell Differentiation - immunology | Infection - genetics | Listeria monocytogenes - pathogenicity | Animals | Adoptive Transfer - methods | Inflammation - genetics | Mice | Dendritic Cells - transplantation | Autoimmune diseases | Bacteria | Cells | Index Medicus
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5. Full Text Emerging therapies for systemic lupus erythematosus — Focus on targeting interferon-alpha
by Lichtman, Eben I and Helfgott, Simon M and Kriegel, Martin A
Clinical immunology (Orlando, Fla.), ISSN 1521-6616, 2012, Volume 143, Issue 3, pp. 210 - 221
Allergy and Immunology | Pin1 | TLR | IRF | Virome | pDC | Proteasome | PDC | Life Sciences & Biomedicine | Immunology | Science & Technology | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Biological and medical sciences | Medical sciences | Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis | Dendritic Cells - immunology | Humans | Interferon-alpha - antagonists & inhibitors | Toll-Like Receptors - immunology | Interferon Regulatory Factors - genetics | Clinical Trials as Topic | Interferon-alpha - immunology | Interferon Regulatory Factors - immunology | Animals | Interferon-alpha - genetics | Lupus Erythematosus, Systemic - genetics | Toll-Like Receptors - genetics | Lupus Erythematosus, Systemic - drug therapy | Lupus Erythematosus, Systemic - immunology | Toll-Like Receptors - antagonists & inhibitors | Dendritic Cells - drug effects | Mice | Lupus | Care and treatment | Systemic lupus erythematosus | Monoclonal antibodies | Lupus erythematosus | Interferon | Biological response modifiers | Index Medicus | Translation | Clinical trials | Genomes | Vaccines | Risk factors | Side effects | Reviews | Toll-like receptors | alpha -Interferon | Autoimmune diseases | Pharmaceuticals | virome | interferonopathies | proteasome | STAT | JAK
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6. Full Text Alpha synuclein deficiency increases CD4+ T‐cells pro‐inflammatory profile in a Nurr1‐dependent manner
by Trudler, Dorit and Levy‐Barazany, Hilit and Nash, Yuval and Samuel, Liron and Sharon, Ronit and Frenkel, Dan
Journal of neurochemistry, ISSN 0022-3042, 01/2020, Volume 152, Issue 1, pp. 61 - 71
Nurr1 | CD4 + T cells | alpha synuclein | multiple sclerosis | Biochemistry & Molecular Biology | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Cell proliferation | Antigens | Parkinson's disease | Cytokines | Neurodegenerative diseases | Myelin | Interleukin | Inflammatory response | Lymphocytes T | siRNA | Inflammation | Synuclein | Nuclear receptors | Experimental allergic encephalomyelitis | CD4 antigen | Nurr1 protein | Lymphocytes | Interferon | Movement disorders | Index Medicus
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7. Full Text A Phase II study of the efficacy and safety of rontalizumab (rhuMAb interferon-α) in patients with systemic lupus erythematosus (ROSE)
by Kalunian, Kenneth C and Merrill, Joan T and Maciuca, Romeo and McBride, Jacqueline M and Townsend, Michael J and Wei, Xiaohui and Davis, John C and Kennedy, William P
Annals of the rheumatic diseases, ISSN 0003-4967, 01/2016, Volume 75, Issue 1, pp. 196 - 202
Life Sciences & Biomedicine | Rheumatology | Science & Technology | Severity of Illness Index | Antibodies, Monoclonal, Humanized - adverse effects | Glucocorticoids - administration & dosage | Antibodies, Monoclonal, Humanized - therapeutic use | Injections, Intravenous | Double-Blind Method | Drug Administration Schedule | Humans | Middle Aged | Immunologic Factors - administration & dosage | Male | Treatment Outcome | Biomarkers - blood | Antibodies, Monoclonal, Humanized - administration & dosage | Injections, Subcutaneous | Lupus Erythematosus, Systemic - drug therapy | Lupus Erythematosus, Systemic - immunology | Adult | Female | Immunologic Factors - adverse effects | Drug Therapy, Combination | Immunologic Factors - therapeutic use | Monoclonal antibodies | Care and treatment | Systemic lupus erythematosus | Research | Health aspects | Interferon alpha | Index Medicus
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8. Full Text Microcystin-LR Induces Endoplasmatic Reticulum Stress and Leads to Induction of NFκB, Interferon-Alpha, and Tumor Necrosis Factor-Alpha
by Christen, Verena and Meili, Nicole and Fent, Karl
Environmental science & technology, ISSN 0013-936X, 04/2013, Volume 47, Issue 7, pp. 3378 - 3385
Engineering | Engineering, Environmental | Life Sciences & Biomedicine | Technology | Environmental Sciences & Ecology | Science & Technology | Environmental Sciences | Fundamental and applied biological sciences. Psychology | Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains | Biological and medical sciences | Microbiology |