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Journal of Immunology, ISSN 0022-1767, 04/2012, Volume 188, Issue 7, pp. 2967 - 2971
The host response to Chikungunya virus is dependent on the direct action of type I IFN on infected nonhematopoietic cells. Prior studies have demonstrated that... 
PATHOGENESIS | VIRUS | PROTEIN | MODEL | IMMUNOLOGY | DISTINCT | Age Factors | Interferon Regulatory Factor-7 - genetics | Interferon Regulatory Factor-3 - genetics | Interferon Regulatory Factor-7 - physiology | Interferon-alpha - genetics | Bone Marrow Transplantation | Hematopoietic Stem Cells - virology | Fibroblasts - metabolism | Animals, Newborn | Chikungunya Fever | Fibroblasts - virology | Toll-Like Receptor 7 - genetics | Interferon-alpha - biosynthesis | Mice, Inbred C57BL | Cells, Cultured | Myeloid Differentiation Factor 88 - genetics | Toll-Like Receptor 7 - deficiency | Hematopoietic Stem Cells - metabolism | Radiation Chimera | Alphavirus Infections - immunology | Chikungunya virus - growth & development | Chikungunya virus - immunology | Interferon Regulatory Factor-3 - physiology | Membrane Glycoproteins - genetics | Mice, Knockout | Host-Pathogen Interactions | Adaptor Proteins, Signal Transducing - physiology | Animals | Interferon Regulatory Factor-3 - deficiency | Myeloid Differentiation Factor 88 - deficiency | Interferon Regulatory Factor-7 - deficiency | Mice | Membrane Glycoproteins - deficiency | Interferon Regulatory Factor-7/deficiency | Toll-Like Receptor 7/genetics | Membrane Glycoproteins/genetics | Hematopoietic Stem Cells/metabolism | Myeloid Differentiation Factor 88/genetics | Life Sciences | Alphavirus Infections/immunology | Immunology | Fibroblasts/metabolism | Chikungunya virus/growth & development | Myeloid Differentiation Factor 88/deficiency | Toll-Like Receptor 7/deficiency | Interferon Regulatory Factor-3/physiology | Interferon Regulatory Factor-3/genetics | Interferon-alpha/biosynthesis | Adaptor Proteins, Signal Transducing/physiology | Hematopoietic Stem Cells/virology | Membrane Glycoproteins/deficiency | Interferon Regulatory Factor-3/deficiency | Chikungunya virus/immunology
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 2176 - 15
Microbial nucleic acid recognition serves as the major stimulus to an antiviral response, implying a requirement to limit the misrepresentation of self nucleic... 
AICARDI-GOUTIERES-SYNDROME | SYSTEMIC-LUPUS-ERYTHEMATOSUS | ACTIVE ENZYME | MAMMALIAN DNA | MULTIDISCIPLINARY SCIENCES | ALPHA | INFLAMMATORY DISEASE | DEOXYRIBONUCLEASE-II | MUTATIONS | EXONUCLEASE TREX1 | NUCLEIC-ACIDS | Endodeoxyribonucleases - immunology | Phosphorylation | Deoxyribonucleases - deficiency | Humans | RNA, Messenger - analysis | Male | Gene Expression Profiling | Erythroblasts - immunology | Signal Transduction - immunology | Deoxyribonucleases - immunology | STAT1 Transcription Factor - metabolism | Female | Endodeoxyribonucleases - deficiency | Child | STAT3 Transcription Factor - metabolism | Interferon-alpha - metabolism | Antiviral Agents - pharmacology | Hereditary Autoinflammatory Diseases - blood | Hereditary Autoinflammatory Diseases - enzymology | Hereditary Autoinflammatory Diseases - immunology | Interferon-alpha - immunology | Up-Regulation - drug effects | Deoxyribonucleases - genetics | Hematopoiesis - immunology | Endodeoxyribonucleases - genetics | Sequence Analysis, RNA | Interferon-alpha - blood | Adolescent | Mutation | Hereditary Autoinflammatory Diseases - genetics | Glomerulonephritis | Neonates | Deformation | Liver | Antibodies | α-Interferon | Microorganisms | Lymphocytes | Hematopoiesis | Peripheral blood | Anti-DNA antibodies | Stat1 protein | Enzyme-linked immunosorbent assay | Deoxyribonucleic acid--DNA | Deoxyribonuclease | Hematology | Anemia | Stat3 protein | Nucleic acids | Ribonucleic acid--RNA | Hemopoiesis | Signaling | Monocytes | Erythroblasts | Fibrosis | Interferon | Endonuclease | Life Sciences | Immunology
Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 12/2011, Volume 204, Issue 12, pp. 1927 - 1935
Most patients with human immunodeficiency virus (HIV) who remain CD4⁺ T-cell deficient on antiretroviral therapy (ART) exhibit marked immune activation. As... 
T lymphocytes | HIV/AIDS | Antiretrovirals | Messenger RNA | HIV | AIDS | Infections | Blood | Apoptosis | Arts | Blood plasma | INFECTIOUS DISEASES | GASTROINTESTINAL-TRACT | MICROBIOLOGY | HIV-1-INFECTED PATIENTS | IMMUNOLOGY | HUMAN-IMMUNODEFICIENCY-VIRUS | TYPE-1 INFECTION | PLASMACYTOID DENDRITIC CELLS | APOPTOSIS-INDUCING LIGAND | AIDS-DEFINING MALIGNANCIES | IMMUNE ACTIVATION | INFECTED PATIENTS | MICROBIAL TRANSLOCATION | fas Receptor - blood | Interferon-alpha - pharmacology | Transcription Factors - blood | Gene Expression - drug effects | Gene Expression - genetics | Humans | Middle Aged | HLA-DR Antigens - blood | Male | RNA, Messenger - metabolism | Transcription Factors - drug effects | CD4-Positive T-Lymphocytes - immunology | HIV Infections - immunology | Lipopolysaccharides - blood | Lymphocyte Activation - immunology | Interferon-alpha - genetics | CD8-Positive T-Lymphocytes - metabolism | Adult | Female | Anti-Retroviral Agents - therapeutic use | Cross-Sectional Studies | HIV Infections - genetics | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | CD4 Lymphocyte Count | Transcription Factors - genetics | Interferon-alpha - immunology | Lipopolysaccharide Receptors - blood | CD57 Antigens - blood | HIV Infections - drug therapy | CD8-Positive T-Lymphocytes - immunology | Antiviral agents | Usage | Physiological aspects | Research | HIV (Viruses) | Risk factors | Lipopolysaccharides
Journal Article
Science, ISSN 0036-8075, 10/2006, Volume 314, Issue 5797, pp. 308 - 312
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2015, Volume 212, Issue 10, pp. 1641 - 1662
Journal Article
Hepatology, ISSN 0270-9139, 08/2017, Volume 66, Issue 2, pp. 344 - 356
We assessed non‐liver‐related non–acquired immunodeficiency syndrome (AIDS)‐related (NLR‐NAR) events and mortality in a cohort of human immunodeficiency virus... 
SUSTAINED VIROLOGICAL RESPONSE | HEART-DISEASE | HIV-INFECTION | ENDOTHELIAL DYSFUNCTION | INCREASED RISK | ANTIVIRAL TREATMENT | CHRONIC KIDNEY-DISEASE | CHRONIC HCV INFECTION | GASTROENTEROLOGY & HEPATOLOGY | CORONARY-ARTERY-DISEASE | BONE TURNOVER | Follow-Up Studies | Coinfection - drug therapy | Humans | Middle Aged | Male | Coinfection - physiopathology | HIV - drug effects | Incidence | Time Factors | Adult | Female | Retrospective Studies | Hepatitis C, Chronic - epidemiology | Drug Therapy, Combination | Databases, Factual | Hepacivirus - drug effects | Hepacivirus - isolation & purification | Risk Assessment | Comorbidity | Ribavirin - therapeutic use | Interferon-alpha - therapeutic use | Treatment Outcome | HIV - isolation & purification | Hepatitis C, Chronic - diagnosis | Hepatitis C, Chronic - drug therapy | Acquired Immunodeficiency Syndrome - drug therapy | Regression Analysis | Spain - epidemiology | Survival Analysis | Acquired Immunodeficiency Syndrome - epidemiology | Acquired Immunodeficiency Syndrome - diagnosis | Cohort Studies | Kidneys | Diabetes mellitus | Liver | Lymphocytes T | Regression analysis | Ribonucleic acid--RNA | Ribavirin | Immunosuppressive agents | Antiretroviral therapy | CD4 antigen | Hepatitis | Bone cancer | Disease transmission | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Fibrosis | Renal failure | Death | Interferon | Diabetes | Hepatitis C | Kidney transplantation | Cancer | Original
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2011, Volume 121, Issue 12, pp. 4889 - 4902
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