X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (5160) 5160
Publication (991) 991
Newsletter (79) 79
Book Review (33) 33
Transcript (16) 16
Newspaper Article (10) 10
Book Chapter (9) 9
Conference Proceeding (7) 7
Dissertation (4) 4
Magazine Article (2) 2
Data Set (1) 1
Reference (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (3530) 3530
index medicus (2657) 2657
animals (2644) 2644
mice (1851) 1851
interferon-beta - genetics (1625) 1625
immunology (1403) 1403
female (1171) 1171
interferon-beta - metabolism (1130) 1130
interferon (1129) 1129
interferon-beta (1035) 1035
male (963) 963
cell line (939) 939
biochemistry & molecular biology (788) 788
virology (778) 778
multiple sclerosis (767) 767
interferon-beta - pharmacology (766) 766
biological response modifiers (698) 698
activation (694) 694
signal transduction (686) 686
cells, cultured (684) 684
interferon-beta - biosynthesis (677) 677
interferon-beta - immunology (677) 677
gene expression (670) 670
interferon beta (670) 670
viruses (666) 666
expression (634) 634
cell biology (611) 611
mice, inbred c57bl (579) 579
adult (569) 569
nf-kappa-b (562) 562
interferon-beta - therapeutic use (551) 551
research (526) 526
health aspects (518) 518
innate immunity (511) 511
gene-expression (492) 492
mice, knockout (473) 473
middle aged (453) 453
molecular sequence data (429) 429
proteins (428) 428
research article (426) 426
virus diseases (418) 418
double-stranded-rna (414) 414
cells (409) 409
genetic aspects (402) 402
infection (397) 397
rig-i (392) 392
cytokines (390) 390
cell line, tumor (388) 388
gene expression regulation (388) 388
dendritic cells (387) 387
multidisciplinary sciences (379) 379
rna (369) 369
induction (367) 367
phosphorylation (360) 360
apoptosis (359) 359
article (354) 354
rna, messenger - metabolism (350) 350
inflammation (342) 342
ifn-beta (341) 341
transfection (341) 341
promoter regions, genetic (339) 339
toll-like receptors (338) 338
neurosciences (332) 332
analysis (329) 329
multiple sclerosis - drug therapy (329) 329
base sequence (326) 326
rna, messenger - genetics (321) 321
genes (318) 318
interferon-alpha - genetics (312) 312
oncology (311) 311
medicine (304) 304
immunity, innate (296) 296
nf-kappa b - metabolism (291) 291
medicine, research & experimental (281) 281
physiological aspects (273) 273
reverse transcriptase polymerase chain reaction (271) 271
microbiology (268) 268
care and treatment (267) 267
immune response (264) 264
infections (263) 263
dna-binding proteins - metabolism (262) 262
virus replication (262) 262
hek293 cells (260) 260
interferon regulatory factor-3 - metabolism (254) 254
science (254) 254
macrophages (250) 250
transcription factors (249) 249
interferon-alpha - pharmacology (248) 248
amino acid sequence (247) 247
biology (247) 247
therapy (247) 247
hela cells (244) 244
immune system (241) 241
cancer (240) 240
immunity (240) 240
protein (240) 240
abridged index medicus (239) 239
clinical neurology (238) 238
transcription, genetic (237) 237
protein binding (233) 233
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (5129) 5129
Japanese (47) 47
Chinese (41) 41
Russian (16) 16
French (10) 10
German (9) 9
Spanish (9) 9
Danish (3) 3
Italian (3) 3
Portuguese (3) 3
Hungarian (2) 2
Polish (1) 1
Swedish (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


The American Journal of Human Genetics, ISSN 0002-9297, 02/2015, Volume 96, Issue 2, pp. 275 - 282
Journal Article
Nature Immunology, ISSN 1529-2908, 02/2016, Volume 17, Issue 2, pp. 140 - 149
Innate sensing of pathogens initiates inflammatory cytokine responses that need to be tightly controlled. We found here that after engagement of Toll-like... 
PATHWAYS | INTERFERON | ACTIVATION | SUMO | BETA-GENE | IFN-GAMMA | NEGATIVE REGULATION | ENHANCER | MICE | IMMUNOLOGY | UP-REGULATION | Chromatin - metabolism | Dendritic Cells - immunology | Gene Expression Profiling | Genetic Loci | Shock, Septic - immunology | Lipopolysaccharides - immunology | Shock, Septic - metabolism | Inflammation - metabolism | Inflammation Mediators - metabolism | Toll-Like Receptors - metabolism | Dendritic Cells - metabolism | Disease Models, Animal | Receptor, Interferon alpha-beta - metabolism | Shock, Septic - genetics | Sumoylation - genetics | Disease Resistance | Disease Susceptibility | Cytokines - metabolism | Signal Transduction | Immunomodulation | Gene Expression Regulation | Inflammation - virology | Inflammation - immunology | Immunity, Innate | Mice, Knockout | Animals | Enhancer Elements, Genetic | Interferon-beta - metabolism | Regulatory Elements, Transcriptional | Sumoylation - immunology | Inflammation - genetics | Protein Binding | Mice | SUMO-1 Protein - metabolism | Chromatin - genetics | Analysis | Influence | Interferon | Inflammation | Research | Biological response modifiers | Gene expression | Health aspects | Risk factors | Shock, Septic/metabolism | Inflammation Mediators/metabolism | Sumoylation/immunology | Interferon-beta/metabolism | Dendritic Cells/metabolism | Inflammation/virology | Inflammation/immunology | Life Sciences | Immunology | Receptor, Interferon alpha-beta/metabolism | Inflammation/genetics | SUMO-1 Protein/metabolism | Cytokines/metabolism | Sumoylation/genetics | Chromatin/metabolism | Inflammation/metabolism | Toll-Like Receptors/metabolism | Lipopolysaccharides/immunology | Shock, Septic/immunology | Chromatin/genetics | Shock, Septic/genetics | Dendritic Cells/immunology
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2014, Volume 289, Issue 1, pp. 13 - 27
Highly pathogenic avian influenza viruses (HPAIV) induce severe inflammation in poultry and men. One characteristic of HPAIV infections is the induction of a... 
TRANSCRIPTIONAL ACTIVATION | STAT Transcription Factor | INDUCED PHOSPHORYLATION | MAP KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | Influenza Virus | STAT Signaling | Highly Pathogenic Avian Influenza Virus (HPAIV) | SERINE PHOSPHORYLATION | p38 MAPK | Endothelium | A VIRUS | Hypercytokinemia | REGULATORY FACTOR-3 | ANTIVIRAL RESPONSES | JAK | Interferon | NF-KAPPA-B | EXPRESSION | Orthomyxoviridae Infections - prevention & control | Humans | Cercopithecus aethiops | Male | Influenza A Virus, H5N1 Subtype - genetics | Orthomyxoviridae Infections - enzymology | Promoter Regions, Genetic - genetics | Orthomyxoviridae Infections - genetics | Phosphorylation - genetics | STAT1 Transcription Factor - metabolism | MAP Kinase Signaling System - genetics | Madin Darby Canine Kidney Cells | Interferon-beta - genetics | Female | p38 Mitogen-Activated Protein Kinases - metabolism | Influenza A Virus, H5N1 Subtype - metabolism | Phosphorylation - drug effects | Cytokines - genetics | Vero Cells | Influenza A Virus, H7N7 Subtype | Gene Expression Regulation - genetics | Orthomyxoviridae Infections - pathology | Enzyme Inhibitors - pharmacology | Interferon-beta - biosynthesis | p38 Mitogen-Activated Protein Kinases - genetics | Imidazoles - pharmacology | STAT1 Transcription Factor - genetics | Gene Expression Regulation - drug effects | Animals | MAP Kinase Signaling System - drug effects | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Dogs | Mice | Mice, Inbred BALB C | Pyridines - pharmacology | Cytokines - biosynthesis | Molecular Bases of Disease
Journal Article
PLoS Pathogens, ISSN 1553-7366, 2014, Volume 10, Issue 4, p. e1003989
Modified vaccinia virus Ankara (MVA) is an attenuated poxvirus that has been engineered as a vaccine against infectious agents and cancers. Our goal is to... 
DOUBLE-STRANDED-RNA | CYCLIC GMP-AMP | KAPPA-B KINASE | COMPLEX CLASS-II | DEPENDENT PROTEIN-KINASE | MICROBIOLOGY | ANTIGEN PRESENTATION | INTERFERON INDUCTION | INTRACELLULAR DNA | VIROLOGY | TOLL-LIKE RECEPTORS | INNATE IMMUNE SENSOR | PARASITOLOGY | Dendritic Cells - immunology | Lysosomes - genetics | Immunity, Innate - genetics | Vaccinia virus - genetics | Viral Proteins - metabolism | Endosomes - metabolism | Bone Marrow Cells - virology | Phosphorylation - genetics | Bone Marrow Cells - immunology | Interferon-beta - genetics | Phosphorylation - immunology | Receptor, Interferon alpha-beta - genetics | Nucleotidyltransferases - metabolism | Vaccinia - metabolism | Protein-Serine-Threonine Kinases - metabolism | Receptor, Interferon alpha-beta - metabolism | Endosomes - genetics | Membrane Proteins - genetics | RNA-Binding Proteins - immunology | Viral Proteins - genetics | Mice, Knockout | Interferon-beta - metabolism | Receptor, Interferon alpha-beta - immunology | Vaccinia - immunology | Virulence Factors - metabolism | Mice | Lysosomes - immunology | RNA-Binding Proteins - metabolism | Endosomes - immunology | RNA-Binding Proteins - genetics | Interferon-beta - immunology | Virulence Factors - genetics | Viral Proteins - immunology | Virulence Factors - immunology | Interferon Regulatory Factor-3 - genetics | Vaccinia virus - immunology | Lysosomes - metabolism | Female | Membrane Proteins - metabolism | Dendritic Cells - virology | Dendritic Cells - metabolism | Interferon Regulatory Factor-3 - immunology | Vaccinia virus - metabolism | Protein-Serine-Threonine Kinases - genetics | Membrane Proteins - immunology | Vaccinia - genetics | Animals | Interferon Regulatory Factor-3 - metabolism | Nucleotidyltransferases - genetics | Protein-Serine-Threonine Kinases - immunology | Nucleotidyltransferases - immunology | Bone Marrow Cells - metabolism | Microbiological research | Dendritic cells | Genetic research | Genetic aspects | Research | Nucleotide sequencing | Vaccinia | Health aspects | DNA sequencing | Proteins | Studies | Smallpox | Transcription factors | Genes | Deoxyribonucleic acid | DNA | Infections | Genomes | Vaccines | Viral infections | Immune system
Journal Article
BMC Genomics, ISSN 1471-2164, 07/2015, Volume 16, Issue 1, p. 517
Background: Resident macrophages in the CNS microglia become activated and produce proinflammatory molecules upon encountering bacteria or viruses. TLRs are a... 
RNA sequencing | Innate immunity | Gene regulation | Toll-like receptor | Microglia | ACTIVATION | RNA | RECEPTOR | CYTOKINE | INDUCTION | INNATE IMMUNE-RESPONSES | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | GENE-EXPRESSION | INHIBITORS | NF-KAPPA-B | MODULATION | Microglia - metabolism | Transcription, Genetic - drug effects | Transcription Initiation Site - drug effects | Immunity, Innate - genetics | Interferon Regulatory Factor-3 - genetics | Transcription Initiation Site - physiology | Inflammation Mediators - metabolism | Interferon-beta - genetics | Epigenesis, Genetic - drug effects | Toll-Like Receptor 3 - genetics | Immunity, Innate - drug effects | Microglia - drug effects | Gene Expression Regulation - genetics | RNA Processing, Post-Transcriptional - drug effects | Toll-Like Receptor 4 - genetics | Up-Regulation - genetics | Signal Transduction - genetics | Transcriptome - drug effects | Transcriptome - genetics | Gene Expression Regulation - drug effects | Up-Regulation - drug effects | Macrophages - metabolism | Animals | RNA Processing, Post-Transcriptional - genetics | Signal Transduction - drug effects | Epigenesis, Genetic - genetics | Lipopolysaccharides - pharmacology | Ligands | Macrophages - drug effects | Mice | Transcription, Genetic - genetics | Toll-like receptors | Epigenetic inheritance | Transcription factors | Gene expression | Analysis | Immune response | Methyltransferases | Genes | DNA binding proteins | Nucleotide sequencing | Genetic transcription | Macrophages | Health aspects | DNA sequencing
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 9, pp. 1 - 6
Journal Article
Science, ISSN 0036-8075, 3/2013, Volume 339, Issue 6126, pp. 1448 - 1453
Type I interferons (IFN-α and IFN-β) are important for protection against many viral infections, whereas type II interferon (IFN-γ) is essential for host... 
Monocytes | Messenger RNA | Tuberculosis | Mycobacterium tuberculosis | Antimicrobials | REPORTS | Leprosy | Infections | Skin | Lesions | Gene expression | LISTERIA-MONOCYTOGENES | ACTIVATION | PROFILES | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | HUMAN TUBERCULOSIS | IL-1-BETA | INDUCTION | DEPENDENT ANTIMICROBIAL PATHWAY | SARCOIDOSIS | LEPROSY | Up-Regulation | Interferon-beta - immunology | Humans | Transcriptome | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - genetics | Monocytes - metabolism | Monocytes - immunology | Interferon-gamma - metabolism | Antimicrobial Cationic Peptides - metabolism | RNA, Messenger - metabolism | Receptors, Calcitriol - genetics | Mycobacterium leprae - immunology | Interferon-beta - genetics | Interleukin-10 - metabolism | beta-Defensins - metabolism | Interferon-gamma - genetics | Antimicrobial Cationic Peptides - genetics | Leprosy, Lepromatous - genetics | Mycobacterium leprae - physiology | Leprosy, Tuberculoid - immunology | beta-Defensins - genetics | Leprosy, Lepromatous - immunology | RNA, Messenger - genetics | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - metabolism | Microbial Viability | Receptors, Calcitriol - metabolism | Leprosy, Tuberculoid - genetics | Tuberculosis - immunology | Leprosy, Lepromatous - metabolism | Interferon-beta - metabolism | Tuberculosis - genetics | Leprosy, Tuberculoid - metabolism | Interferon-gamma - immunology | Interleukin-10 - genetics | Interleukins | Physiological aspects | Host-parasite relationships | Anti-infective agents | Interferon | Genetic aspects | Health aspects | Antimicrobial agents | Pathogenesis | Genes | Bacteria | Human behavior | Antiinfectives and antibacterials | Digital signatures
Journal Article
JOURNAL OF CLINICAL PERIODONTOLOGY, ISSN 0303-6979, 12/2014, Volume 41, Issue 12, pp. 1122 - 1131
Journal Article
British Journal of Cancer, ISSN 0007-0920, 01/2016, Volume 114, Issue 2, pp. 177 - 187
Background: Oestrogen receptor-negative (ER-) breast cancer is intrinsically sensitive to chemotherapy. However, tumour response is often incomplete, and... 
CELLS | REDUCES TUMOR-GROWTH | STAT1 | DNA-DAMAGE | chemotherapy | IFN | THERAPY | NEOADJUVANT CHEMOTHERAPY | ONCOLOGY | ER-negative breast cancer | GENE-EXPRESSION | RESISTANCE | PATHWAY ANALYSIS | predictive signature | XENOGRAFTS | Caspase 7 - metabolism | Immunohistochemistry | Receptors, Estrogen - metabolism | Cytoskeletal Proteins - genetics | Humans | Intracellular Signaling Peptides and Proteins - drug effects | Caspase 3 - metabolism | Gene Expression Profiling | Intracellular Signaling Peptides and Proteins - metabolism | Interferon-gamma - metabolism | Carrier Proteins - drug effects | Mitochondrial Proteins - drug effects | STAT1 Transcription Factor - metabolism | Mitochondrial Proteins - metabolism | Caspase 3 - genetics | Interferon-beta - genetics | Cytokines - genetics | Intracellular Signaling Peptides and Proteins - genetics | Real-Time Polymerase Chain Reaction | Ubiquitins - metabolism | Caspase 7 - drug effects | Antigens - drug effects | Caspase 7 - genetics | Membrane Proteins - genetics | Myxovirus Resistance Proteins - drug effects | Capecitabine - pharmacology | STAT1 Transcription Factor - genetics | Breast Neoplasms - drug therapy | Blotting, Western | Breast Neoplasms - genetics | Interferon-beta - metabolism | Signal Transduction - drug effects | Mice, Nude | Membrane Proteins - drug effects | Mice | Myxovirus Resistance Proteins - genetics | Ubiquitins - drug effects | Antigens - genetics | Neoplasm Transplantation | Phosphorylation | Ubiquitins - genetics | Gene Expression Regulation, Neoplastic | Interferon-gamma - drug effects | STAT1 Transcription Factor - drug effects | Mitochondrial Proteins - genetics | Interferon-beta - drug effects | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Breast Neoplasms - metabolism | In Situ Hybridization | Caspase 3 - drug effects | Cytoskeletal Proteins - metabolism | Female | Cytoskeletal Proteins - drug effects | Membrane Proteins - metabolism | Interferon-gamma - genetics | Cytokines - metabolism | Antigens - metabolism | Cisplatin - pharmacology | Xenograft Model Antitumor Assays | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Cytokines - drug effects | Myxovirus Resistance Proteins - metabolism | Translational Therapeutics
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2012, Volume 7, Issue 11, p. e49047
Inflammatory conditions may promote tumor progression and aggressiveness. In previous reports, we found a group of breast cancer tumors characterized by... 
MATRIX METALLOPROTEINASES | CELLS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | HUMAN PAPILLOMA-VIRUS | GROWTH-FACTOR | INHIBITORS | TUMOR-GROWTH | CANCER | EXPRESSION | PROMOTES ANGIOGENESIS | Inflammation - pathology | Interleukin-1 Receptor-Associated Kinases - metabolism | Leukocytes, Mononuclear - metabolism | Interleukin-1 Receptor-Associated Kinases - genetics | Follow-Up Studies | Humans | NF-kappa B - metabolism | Interleukins - metabolism | Breast Neoplasms - metabolism | Interleukins - genetics | Tissue Inhibitor of Metalloproteinase-1 - metabolism | Inflammation - metabolism | Neoplasm Metastasis | Chemokine CCL3 - genetics | Claudin-3 - genetics | Interferon-beta - genetics | Chemokine CCL3 - metabolism | Claudin-3 - metabolism | Female | Carcinoma - pathology | Matrix Metalloproteinase 1 - genetics | Myeloid Differentiation Factor 88 - genetics | Matrix Metalloproteinase 11 - metabolism | Up-Regulation - genetics | Disease Progression | Leukocytes, Mononuclear - pathology | Tissue Inhibitor of Metalloproteinase-1 - genetics | ADAM Proteins - metabolism | Annexin A2 - genetics | Breast Neoplasms - genetics | Interferon-beta - metabolism | NF-kappa B - genetics | Breast Neoplasms - pathology | Matrix Metalloproteinase 11 - genetics | Inflammation - genetics | Carcinoma - genetics | Carcinoma - metabolism | ADAM Proteins - genetics | Matrix Metalloproteinase 1 - metabolism | Annexin A2 - metabolism | Myeloid Differentiation Factor 88 - metabolism | Breast cancer | Inflammation | Prognosis | B cells | Annexins | Analysis | Gene regulation | Metastasis | Matrix metalloproteinase | Tissue inhibitor of metalloproteinase 1 | Metastases | Interleukin 6 | Proteins | Ethics | Angiogenesis | Breast carcinoma | Interleukin 5 | Interleukin 1 | Metalloproteinase | Growth factors | Interstitial collagenase | IRAK protein | ADAMTS-1 protein | Cytokines | Gene expression | Interleukin 17 | Womens health | Medical prognosis | MyD88 protein | Breast | Chemokines | Tumors | Cancer
Journal Article