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Journal Article
Journal Article
Journal Article
Nature communications, ISSN 2041-1723, 2011, Volume 2, Issue 1, p. 240
The immune system can both promote and suppress cancer. Chronic inflammation and proinflammatory cytokines such as interleukin (IL)-1 and IL-6 are considered... 
LUNG-CANCER | INTERFERON-INDUCIBLE PROTEIN-10 | NECROSIS IN-VIVO | PROGNOSTIC-FACTORS | INTERLEUKIN-1 RECEPTOR ANTAGONIST | IFN-GAMMA | MULTIDISCIPLINARY SCIENCES | CD4(+) T-CELLS | ADJUVANT THERAPY | CARCINOMA | EXPRESSION | Angiostatic Proteins - immunology | Immunohistochemistry | Neoplasms - metabolism | Interleukin-1alpha - immunology | Chemokine CXCL9 - biosynthesis | Tumor Microenvironment | Multiple Myeloma - immunology | Th2 Cells - immunology | Th1 Cells - immunology | CD4-Positive T-Lymphocytes - immunology | Chemokine CXCL10 - biosynthesis | Inflammation - metabolism | Interleukin-2 - immunology | Chemokine CXCL10 - immunology | Lymphoma, B-Cell - immunology | Interleukin-1beta - biosynthesis | Macrophages - immunology | Interleukin-12 - biosynthesis | Lymphoma, B-Cell - metabolism | Signal Transduction | Angiostatic Proteins - biosynthesis | CD4-Positive T-Lymphocytes - cytology | CD4-Positive T-Lymphocytes - metabolism | Interleukin-1beta - immunology | Chemokine CXCL9 - immunology | Inflammation - immunology | Macrophages - cytology | Mice, SCID | Multiple Myeloma - metabolism | Macrophages - metabolism | Multiple Myeloma - pathology | Animals | Neoplasms - immunology | Interferon-gamma - immunology | Interleukin-12 - immunology | Interleukin-6 - immunology | Lymphoma, B-Cell - pathology | Cell Line, Tumor | Interleukin-6 - biosynthesis | Interleukin-1alpha - biosynthesis | Mice | Interleukin-2 - biosynthesis | Neoplasms - pathology | Interferon-gamma - biosynthesis
Journal Article
Blood, ISSN 1528-0020, 2005, Volume 106, Issue 7, pp. 2366 - 2374
Journal Article
PLoS biology, ISSN 1545-7885, 2011, Volume 9, Issue 3, p. e1000598
.... Here we report an intimate link between the innate immune response to infection and regulation of the sterol metabolic network characterized by down-regulation of sterol biosynthesis by an interferon... 
CHOLESTEROL-METABOLISM | REDUCTASE INHIBITORS | MULTIPLE-SCLEROSIS | PROBE LEVEL DATA | VIRUS-RNA REPLICATION | NUCLEAR RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOLOGY | GENE-EXPRESSION | MURINE CYTOMEGALOVIRUS | INFLAMMATORY RESPONSE | CORONARY-ARTERY-DISEASE | NIH 3T3 Cells | Interferon-beta - physiology | Simvastatin - pharmacology | Sterols - biosynthesis | Macrophages - virology | RNA Interference | Herpesviridae Infections - metabolism | Macrophages - immunology | Antiviral Agents - pharmacology | Signal Transduction | Down-Regulation | Mice, Inbred C57BL | Interferon-beta - biosynthesis | Interferon-gamma - physiology | Cholesterol - metabolism | Immunity, Innate | Sterol Regulatory Element Binding Protein 2 - physiology | Muromegalovirus - immunology | Macrophages - metabolism | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Interferon-beta - pharmacology | Mice | Mice, Inbred BALB C | Interferon-gamma - biosynthesis | Interferon-gamma - pharmacology | Herpesviridae Infections - immunology | Sterols | Genetic aspects | Interferon | Dosage and administration | Lipid metabolism | Research | Properties | Health aspects | Immunity | Cytomegalovirus | Biomedical research | Metabolites | Biosynthesis | Experiments | Viral infections | Cholesterol | Colesterol | Biosíntesi | Interferó
Journal Article
Nature communications, ISSN 2041-1723, 2019, Volume 10, Issue 1, pp. 498 - 13
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 2008, Volume 181, Issue 10, pp. 7420 - 7427
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 06/2006, Volume 79, Issue 6, pp. 1279 - 1285
Dendritic cells (DCs) play an important role in innate and adaptive immune responses. In addition to their phagocytic activity, DCs present foreign antigens to... 
Human | Cytokines | Cell activation | SIGNAL-TRANSDUCTION PATHWAYS | ACTIVATION | cell activation | RECEPTOR | ANTIGEN PRESENTATION | IMMUNOLOGY | CUTTING EDGE | CELL BIOLOGY | B-CELLS | HUMAN NK | COMMON GAMMA-CHAIN | cytokines | HEMATOLOGY | human | T-CELLS | IFN-ALPHA | Dendritic Cells - immunology | Humans | Membrane Glycoproteins - biosynthesis | Receptors, Interleukin-1 - genetics | Tumor Necrosis Factor-alpha - genetics | Suppressor of Cytokine Signaling 1 Protein | Gene Expression Profiling | Lipopolysaccharides - antagonists & inhibitors | RNA, Messenger - biosynthesis | Interleukins - physiology | T-Lymphocytes - metabolism | Chemokines, CC - biosynthesis | Cells, Cultured - immunology | Chemokines, CXC - biosynthesis | Cytokines - genetics | Intracellular Signaling Peptides and Proteins - genetics | Interleukin-12 - biosynthesis | Chemokine CCL5 | Cells, Cultured - drug effects | Receptors, Interleukin-21 | Lymphocyte Activation | Repressor Proteins - genetics | Suppressor of Cytokine Signaling Proteins - genetics | Toll-Like Receptor 4 - genetics | Receptors, Interleukin-1 - biosynthesis | Receptors, Interleukin - genetics | Dendritic Cells - secretion | Feedback, Physiological | Macrophages - metabolism | Repressor Proteins - biosynthesis | T-Lymphocytes - immunology | Cells, Cultured - metabolism | HLA-DR Antigens - biosynthesis | Suppressor of Cytokine Signaling Proteins - biosynthesis | Tumor Necrosis Factor-alpha - biosynthesis | Receptors, Interleukin - biosynthesis | Toll-Like Receptor 4 - biosynthesis | Interleukin-12 - genetics | Dendritic Cells - drug effects | Interleukins - pharmacology | Receptors, Interferon - genetics | Dendritic Cells - metabolism | RNA, Messenger - genetics | Cell Communication | Recombinant Proteins - pharmacology | Chemokines, CXC - genetics | Membrane Glycoproteins - genetics | Gene Expression Regulation - drug effects | Suppressor of Cytokine Signaling 3 Protein | Chemokines, CC - genetics | Macrophages - drug effects | Interleukin-21 Receptor alpha Subunit | Receptors, Interferon - biosynthesis | Cytokines - biosynthesis | Interferon-gamma - pharmacology
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 02/2012, Volume 91, Issue 2, pp. 299 - 309
NK cells control tumor and virus-infected cells through releasing cytotoxic granules and proinflammatory cytokines. IFN-gamma and TNF-alpha secretions and... 
NK cytotoxicity | Degranulation | Adhesion molecules | INTERCELLULAR-ADHESION MOLECULE-1 | SUSCEPTIBILITY | INHIBITORY RECEPTORS | MEDIATED LYSIS | IMMUNOLOGY | CELL BIOLOGY | INTERFERON-GAMMA | NK CELLS | adhesion molecules | GENE-EXPRESSION | degranulation | MELANOMA-CELLS | HEMATOLOGY | CYTOTOXICITY | NKG2D LIGAND EXPRESSION | Up-Regulation | Humans | Tumor Necrosis Factor-alpha - genetics | Recombinant Fusion Proteins - physiology | GPI-Linked Proteins - biosynthesis | Intercellular Signaling Peptides and Proteins - biosynthesis | NF-kappa B - metabolism | Cytotoxicity, Immunologic - physiology | HLA Antigens - genetics | B7 Antigens - biosynthesis | Transfection | B7 Antigens - genetics | Intercellular Adhesion Molecule-1 - biosynthesis | Killer Cells, Natural - immunology | Interferon-gamma - genetics | HLA Antigens - biosynthesis | Intracellular Signaling Peptides and Proteins - genetics | RNA, Small Interfering - pharmacology | Gene Expression Regulation | Intercellular Signaling Peptides and Proteins - genetics | Interferon-gamma - physiology | Drug Synergism | Intercellular Adhesion Molecule-1 - genetics | Tumor Necrosis Factor-alpha - physiology | Cell Line, Tumor | Killer Cells, Natural - metabolism | Tumor Necrosis Factor-alpha - biosynthesis | Interferon-gamma - biosynthesis | GPI-Linked Proteins - genetics
Journal Article