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Journal of Immunology, ISSN 0022-1767, 07/2010, Volume 185, Issue 1, pp. 302 - 312
Mesenchymal stem cells (MSCs) exert immunomodulatory properties via the inhibition of T cell activation and proliferation. Because of the deleterious role of... 
PROGENITOR CELLS | GROWTH-FACTOR-BETA | TGF-BETA | ROR-GAMMA-T | DENDRITIC CELLS | INTERFERON-GAMMA | SPECIFICITY | NITRIC-OXIDE | IMMUNOLOGY | LYMPHOCYTE-PROLIFERATION | PROSTAGLANDIN-E2 | Cell Communication - immunology | T-Lymphocytes, Regulatory - metabolism | CD18 Antigens - physiology | Coculture Techniques | Humans | Interleukin-17 - physiology | L Cells (Cell Line) | T-Lymphocytes, Regulatory - pathology | Mesenchymal Stromal Cells - immunology | T-Lymphocytes, Regulatory - immunology | CD11a Antigen - physiology | Cell Movement - immunology | T-Lymphocytes, Helper-Inducer - immunology | Bone Marrow Cells - immunology | Intercellular Adhesion Molecule-1 - biosynthesis | Inflammation Mediators - metabolism | Receptors, CCR6 - metabolism | T-Lymphocytes, Helper-Inducer - cytology | Inflammation Mediators - physiology | Receptors, CCR6 - physiology | CD11a Antigen - metabolism | Bone Marrow Cells - cytology | Cells, Cultured | Interferon-gamma - physiology | Immunophenotyping | Interleukin-17 - biosynthesis | CD18 Antigens - metabolism | Cell Adhesion - immunology | Cell Differentiation - immunology | Animals | Interleukin-17 - antagonists & inhibitors | Tumor Necrosis Factor-alpha - physiology | Growth Inhibitors - physiology | Ligands | Mice | Mesenchymal Stromal Cells - pathology | Bone Marrow Cells - metabolism
Journal Article
Oral Diseases, ISSN 1354-523X, 05/2002, Volume 8, Issue 3, pp. 147 - 159
Bone is continuously destroyed and reformed to maintain constant bone volume and calcium homeostasis in vertebrates throughout their lives. Osteoblasts and... 
macrophage colony‐stimulating factor | Smad | osteoblast | osteoclast | receptor activator of nuclear factor κB ligand | bone morphogenetic proteins | Osteoblast | Bone morphogenetic proteins | Osteoclast | Receptor activator of nuclear factor κB ligand | Macrophage colony-stimulating factor | CLEIDOCRANIAL DYSPLASIA | COLONY-STIMULATING FACTOR | BONE MORPHOGENETIC PROTEIN-2 | C2C12 MYOBLASTS | receptor activator of nuclear factor kappa B ligand | LYMPH-NODE ORGANOGENESIS | INHIBITS MYOGENIC DIFFERENTIATION | DENTISTRY, ORAL SURGERY & MEDICINE | RECEPTOR ACTIVATOR | TGF-BETA-SUPERFAMILY | NF-KAPPA-B | macrophage colony-stimulating factor | CELL-LINE | Osteogenesis - physiology | Bone Morphogenetic Proteins - physiology | Bone Remodeling - physiology | Receptors, Tumor Necrosis Factor - physiology | Osteoprotegerin | Trans-Activators - physiology | Neoplasm Proteins | Interleukin-1 - physiology | Core Binding Factor Alpha 1 Subunit | Osteoclasts - physiology | Cell Differentiation - physiology | Bone Resorption - physiopathology | DNA-Binding Proteins - physiology | Transcription Factors - physiology | Osteoblasts - physiology | Transforming Growth Factor beta - physiology | Cell Communication | Interferon-gamma - physiology | Receptors, Cytoplasmic and Nuclear - physiology | Glycoproteins - physiology | Mice, Knockout | Animals | Lipopolysaccharides - pharmacology | NF-kappa B - physiology | Smad Proteins | Tumor Necrosis Factor-alpha - physiology | Signal Transduction - physiology | Mice
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 10/2004, Volume 173, Issue 7, pp. 4479 - 4491
TLRs are pattern recognition receptors that initiate innate immune responses. TLR9 detects microbial DNA with hypomethylated CpG motifs and in humans is... 
SYSTEMIC-LUPUS-ERYTHEMATOSUS | SIGNALING PATHWAYS | TARGETED DISRUPTION | DENDRITIC CELLS | INTERFERON-GAMMA | SYNERGISTIC ACTIVATION | TOLL-LIKE RECEPTORS | CD40-MEDIATED ACTIVATION | IMMUNOLOGY | NF-KAPPA-B | BACTERIAL-DNA | Receptors, Immunologic - physiology | Humans | Membrane Glycoproteins - biosynthesis | Transcriptional Activation - drug effects | Immunity, Innate - genetics | Interleukin-1 Receptor-Associated Kinases | Toll-Like Receptor 9 | Receptors, Antigen, B-Cell - metabolism | Transcriptional Activation - immunology | Chloroquine - pharmacology | Toll-Like Receptors | Lymphocyte Activation - genetics | Membrane Glycoproteins - physiology | Immunoglobulin G - biosynthesis | Membrane Proteins - physiology | Receptors, Antigen, B-Cell - physiology | Receptors, Cell Surface - physiology | Immunoglobulin Class Switching - drug effects | Adjuvants, Immunologic - physiology | NF-kappa B p50 Subunit | Signal Transduction - genetics | Immunoglobulin Constant Regions - metabolism | Response Elements - immunology | Antigens, Differentiation - physiology | Immunoglobulin mu-Chains - genetics | Adaptor Proteins, Signal Transducing | B-Cell Activating Factor | B-Lymphocytes - immunology | Immunoglobulin G - genetics | Signal Transduction - drug effects | Up-Regulation - immunology | Tumor Necrosis Factor-alpha - physiology | Gene Rearrangement, B-Lymphocyte - drug effects | Immunoglobulin G - metabolism | CD40 Ligand - physiology | DNA, Bacterial - pharmacology | Immunoglobulin gamma-Chains - genetics | Interleukin-10 - physiology | Cytidine Deaminase - biosynthesis | Signal Transduction - immunology | DNA, Bacterial - physiology | Immunoglobulin Constant Regions - genetics | Immunoglobulin gamma-Chains - metabolism | Receptors, Cell Surface - biosynthesis | Cell Line | Proteins - physiology | B-Lymphocytes - enzymology | Immunoglobulin mu-Chains - metabolism | Myeloid Differentiation Factor 88 | B-Lymphocytes - drug effects | TNF Receptor-Associated Factor 6 | Protein Kinases - physiology | NF-kappa B - physiology | Promoter Regions, Genetic - immunology | Immunoglobulin Class Switching - genetics | Interleukin-10 - pharmacology
Journal Article
Nature Medicine, ISSN 1078-8956, 03/2010, Volume 16, Issue 3, pp. 279 - 285
Control of blood vessel tone is central to vascular homeostasis. Here we show that metabolism of tryptophan to kynurenine by indoleamine 2,3-dioxygenase (Ido)... 
MEDICINE, RESEARCH & EXPERIMENTAL | TRYPTOPHAN-METABOLISM | NITRIC-OXIDE SYNTHASE | MURINE CEREBRAL MALARIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | INDOLEAMINE 2,3-DIOXYGENASE EXPRESSION | HEME OXYGENASE-1-DEFICIENT MICE | BLOOD-PRESSURE | CELL BIOLOGY | STIMULATED PHOSPHOPROTEIN VASP | SOLUBLE GUANYLYL CYCLASE | L-ARGININE | ENDOTOXIC-SHOCK | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Coronary Vessels - physiopathology | Kynurenine - biosynthesis | Endothelium, Vascular - enzymology | Kynurenine - physiology | Endothelium, Vascular - physiology | Dose-Response Relationship, Drug | Plasmodium berghei | Tryptophan - blood | Endotoxemia - physiopathology | Guanylate Cyclase - physiology | Blood Pressure - drug effects | Blood Pressure - physiology | Muscle, Smooth, Vascular - physiology | Muscle, Smooth, Vascular - drug effects | Rats, Inbred SHR | Coronary Vessels - drug effects | Endothelium-Dependent Relaxing Factors - physiology | Kynurenine - pharmacology | Mice, Inbred C57BL | Endothelium, Vascular - physiopathology | Interferon-gamma - physiology | Rats | Guanylate Cyclase - metabolism | Adenylyl Cyclases - metabolism | Animals | Tryptophan - physiology | Malaria - physiopathology | Mice | Tryptophan - pharmacology | Enzyme Activation - physiology | Indoleamine-Pyrrole 2,3,-Dioxygenase - antagonists & inhibitors | Indoleamine-Pyrrole 2,3,-Dioxygenase - physiology | Inflammation - physiopathology | Amino acids | Inflammation | Research | Endothelium-derived relaxing factors | Health aspects | Endothelium | Neurotransmitters | Blood pressure | Metabolism | Rodents | Inflammatory diseases
Journal Article
Placenta, ISSN 0143-4004, 2011, Volume 32, Issue 2, pp. S154 - S158
Abstract During human pregnancy, the uterine spiral arteries are progressively remodelled to form dilated conduits lacking maternal vasomotor control. This... 
Internal Medicine | Obstetrics and Gynecology | Remodelling | EVT | Myometrium | Uterine natural killer cells | Elastin | Trophoblast | Leukocytes | Decidua | Macrophages | Artery | Invasion | Extracellular matrix | Vascular smooth muscle cells | CHEMOKINES | DEVELOPMENTAL BIOLOGY | OBSTETRICS & GYNECOLOGY | IN-VITRO | REPRODUCTIVE BIOLOGY | INTERFACE | HUMAN ENDOMETRIUM | NATURAL-KILLER-CELLS | NECROSIS-FACTOR-ALPHA | MATRIX METALLOPROTEINASES | NK CELLS | METALLOELASTASE MMP-12 | Matrix Metalloproteinases, Secreted - metabolism | Decidua - cytology | Angiogenesis Inhibitors - physiology | Humans | Cell Communication - physiology | Culture Media, Conditioned - pharmacology | Interferon-gamma - metabolism | Leukocytes - physiology | Arteries - cytology | Cell Movement - physiology | Chemotaxis, Leukocyte - physiology | Peptides - metabolism | Uterus - physiology | Chemotactic Factors - metabolism | Arteries - physiology | Extracellular Matrix - physiology | Female | Trophoblasts - cytology | Uterus - blood supply | Muscle, Smooth, Vascular - physiology | Pregnancy - physiology | Leukocytes - cytology | Muscle, Smooth, Vascular - drug effects | Elastin - metabolism | Angiopoietins - metabolism | Muscle, Smooth, Vascular - cytology | Killer Cells, Natural - physiology | Killer Cells, Natural - cytology | Animals | Matrix Metalloproteinase 12 - physiology | Trophoblasts - physiology | Vascular Endothelial Growth Factor C - metabolism | Uterus - cytology | Blood Coagulation Factors - physiology | Pregnancy | Chronologies | Proteases | Pregnant women | Arteries
Journal Article
JOURNAL OF EXPERIMENTAL MEDICINE, ISSN 0022-1007, 03/2011, Volume 208, Issue 3, pp. 491 - 503
Journal Article