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1. Full Text A high-throughput single-cell analysis of human CD8 + T cell functions reveals discordance for cytokine secretion and cytolysis
by Varadarajan, Navin and Julg, Boris and Yamanaka, Yvonne J and Chen, Huabiao and Ogunniyi, Adebola O and McAndrew, Elizabeth and Porter, Lindsay C and Piechocka-Trocha, Alicja and Hill, Brenna J and Douek, Daniel C and Pereyra, Florencia and Walker, Bruce D and Love, J. Christopher
The Journal of clinical investigation, ISSN 0021-9738, 11/2011, Volume 121, Issue 11, pp. 4322 - 4331
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Adaptive Immunity | T-Lymphocytes, Cytotoxic - immunology | HIV Core Protein p24 - immunology | Humans | HIV Long-Term Survivors | Antigen-Presenting Cells - immunology | HIV Infections - immunology | Single-Cell Analysis - methods | CD8-Positive T-Lymphocytes - immunology | In Vitro Techniques | Cytokines - biosynthesis | Interferon-gamma - biosynthesis | Cytotoxicity, Immunologic | High-Throughput Screening Assays - methods | Physiological aspects | Cytokines | Properties | Cell death | CD8 lymphocytes | Index Medicus | Abridged Index Medicus | Technical Advance
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2. Full Text Rapid allergen‐induced interleukin‐17 and interferon‐γ secretion by skin‐resident memory CD8+ T cells
by Schmidt, Jonas D and Ahlström, Malin G and Johansen, Jeanne D and Dyring‐Andersen, Beatrice and Agerbeck, Christina and Nielsen, Morten M and Poulsen, Steen S and Woetmann, Anders and Ødum, Niels and Thomsen, Allan R and Geisler, Carsten and Bonefeld, Charlotte M
Contact dermatitis, ISSN 0105-1873, 04/2017, Volume 76, Issue 4, pp. 218 - 227
IL‐1β | IL‐17A | tissue‐resident T cells | allergic contact dermatitis | IFN‐γ | local memory | IFN-γ | IL-17A | tissue-resident T cells | IL-1β | Allergy | Life Sciences & Biomedicine | Dermatology | Science & Technology | Dermatitis, Contact - immunology | Animals | Humans | Immunologic Memory | Mice | Interleukin-17 - biosynthesis | CD8-Positive T-Lymphocytes - immunology | Interferon-gamma - biosynthesis | Skin - immunology | Index Medicus
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3. Full Text Hexabromocyclododecane and tetrabromobisphenol A alter secretion of interferon gamma (IFN-γ) from human immune cells
by Almughamsi, Haifa and Almughamsi, Haifa and Whalen, Margaret M and Whalen, Margaret M
Archives of toxicology, ISSN 0340-5761, 7/2016, Volume 90, Issue 7, pp. 1695 - 1707
Biomedicine | Environmental Health | Occupational Medicine/Industrial Medicine | Tetrabromobisphenol A | Pharmacology/Toxicology | Immune cells | Hexabromocyclododecane | Biomedicine general | p44/42 | Life Sciences & Biomedicine | Toxicology | Science & Technology | Cell Survival - drug effects | Natural Killer T-Cells - drug effects | Leukocytes, Mononuclear - drug effects | Enzyme-Linked Immunosorbent Assay | Leukocytes, Mononuclear - secretion | Humans | Interferon-gamma - secretion | Cells, Cultured | Hydrocarbons, Brominated - toxicity | Dose-Response Relationship, Drug | Flame Retardants - toxicity | Leukocytes, Mononuclear - immunology | Polybrominated Biphenyls - toxicity | Natural Killer T-Cells - immunology | Natural Killer T-Cells - secretion | Killer cells | Fireproofing agents | Biological response modifiers | Epoxy resins | Cells | Interferon gamma | Interferon | Immune system | Index Medicus | p44 | immune cells
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4. Full Text Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5
by Fuss, IJ and Neurath, M and Boirivant, M and Klein, JS and de la Motte, C and Strong, SA and Fiocchi, C and Strober, W
The Journal of immunology (1950), ISSN 0022-1767, 08/1996, Volume 157, Issue 3, pp. 1261 - 1270
Life Sciences & Biomedicine | Immunology | Science & Technology | CD4 Antigens - immunology | Signal Transduction | Humans | Interleukin-5 - biosynthesis | Colitis, Ulcerative - immunology | Crohn Disease - immunology | CD4-Positive T-Lymphocytes - immunology | Interleukin-4 - biosynthesis | Flow Cytometry | Mucous Membrane - immunology | Cell Division | CD3 Complex - immunology | Cell Differentiation | Interleukin-2 - biosynthesis | CD2 Antigens - immunology | Interferon-gamma - biosynthesis | Index Medicus | Abridged Index Medicus
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5. Full Text Intracellular trafficking and secretion of inflammatory cytokines
by Stow, Jennifer L and Murray, Rachael Z
Cytokine & growth factor reviews, ISSN 1359-6101, 2013, Volume 24, Issue 3, pp. 227 - 239
Advanced Basic Science | Conventional secretion | Granules | Unconventional secretion | Cytokine secretion | SNAREs | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | rab GTP-Binding Proteins - metabolism | Secretory Pathway - physiology | Humans | Interferon-gamma - secretion | Tumor Necrosis Factor-alpha - secretion | Cytokines - secretion | Protein Transport - physiology | SNARE Proteins - metabolism | Inflammation - physiopathology | Interleukins - secretion | Cytokines | RNA | Protein biosynthesis
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6. Full Text Extracellular ISG15 Signals Cytokine Secretion through the LFA-1 Integrin Receptor
by Swaim, Caleb D and Scott, Ariella F and Canadeo, Larissa A and Huibregtse, Jon M
Molecular cell, ISSN 1097-2765, 11/2017, Volume 68, Issue 3, pp. 581 - 590.e5
natural killer cells | SRC family kinases | IFN-γ | integrin receptor | LFA-1 | UBAITs | CD11a/αL | ISG15 | mycobacteria | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Ubiquitins - genetics | Humans | Lymphocyte Function-Associated Antigen-1 - metabolism | Interferon-gamma - metabolism | CD11a Antigen - genetics | HEK293 Cells | src-Family Kinases - metabolism | Interleukin-10 - metabolism | Killer Cells, Natural - immunology | Interleukin-10 - secretion | Cytokines - genetics | Ubiquitins - metabolism | CD11a Antigen - metabolism | Killer Cells, Natural - secretion | Cytokines - metabolism | Signal Transduction | Jurkat Cells | Interferon-gamma - secretion | Mice, Inbred C57BL | Mice, Knockout | CD18 Antigens - metabolism | Intercellular Adhesion Molecule-1 - metabolism | Animals | Lymphocyte Function-Associated Antigen-1 - genetics | Intercellular Adhesion Molecule-1 - genetics | Protein Binding | Killer Cells, Natural - metabolism | Ubiquitin | Drug resistance in microorganisms | Cytokines | Immunotherapy | Integrins | Killer cells | Index Medicus | SRC Family Kinases | Natural Killer Cells | Mycobacteria | Integrin Receptor | αL | CD11a
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7. Full Text Exosome secretion by eosinophils: A possible role in asthma pathogenesis
by Mazzeo, Carla, PhD and Cañas, José Antonio, MSc and Zafra, Maria Paz, MSc and Rojas Marco, Ainara, MD and Fernández-Nieto, Mar, MD, PhD and Sanz, Veronica, VET and Mittelbrunn, María, PhD and Izquierdo, Manuel, PhD and Baixaulli, Francesc, MSc and Sastre, Joaquín, MD, PhD and del Pozo, Victoria, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2014, Volume 135, Issue 6, pp. 1603 - 1613
Allergy and Immunology | CD63 | multivesicular bodies | IFN-γ | secretion | exosomes | lysobisphosphatidic acid | eosinophils | endosomes | biomarker | Asthma | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Exosomes - metabolism | Asthma - metabolism | Cell Fractionation | Eosinophils - metabolism | Eosinophils - drug effects | Humans | Eosinophils - immunology | Organelle Size | Case-Control Studies | Asthma - immunology | Exosomes - immunology | Multivesicular Bodies - immunology | Exosomes - ultrastructure | Asthma - diagnosis | Biomarkers - metabolism | Eosinophils - ultrastructure | Microscopy, Electron, Transmission | Cell Separation | Multivesicular Bodies - ultrastructure | Biomarkers - analysis | Chemokine CCL11 - pharmacology | Multivesicular Bodies - metabolism | Primary Cell Culture | Asthma - pathology | Interferon-gamma - pharmacology | Studies | Cytokines | Disease | Pathogenesis | Biomarkers | Patients | Index Medicus | Abridged Index Medicus
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8. Full Text Detection of IFN-γ secretion by T cells collected before and after successful treatment of early lyme disease
by Callister, Steven M and Jobe, Dean A and Stuparic-Stancic, Aleksandra and Miyamasu, Misato and Boyle, Jeff and Dattwyler, Raymond J and Arnaboldi, Paul M
Clinical infectious diseases, ISSN 1058-4838, 05/2016, Volume 62, Issue 10, pp. 1235 - 1241
Lyme disease | Borrelia burgdorferi | IFN-γ | cytokine release assay | T cell | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Borrelia burgdorferi - immunology | Doxycycline - therapeutic use | Lyme Disease - epidemiology | Humans | Interferon-gamma - secretion | Middle Aged | Male | Interferon-gamma - metabolism | Young Adult | Anti-Bacterial Agents - therapeutic use | Lyme Disease - immunology | Lyme Disease - drug therapy | Interferon-gamma - immunology | Adult | Female | T-Lymphocytes - immunology | Aged | Interferon-gamma Release Tests - methods | Lyme Disease - diagnosis | Antibodies, Bacterial - blood | Interferon-gamma - blood | Serologic Tests | Care and treatment | Dosage and administration | Research | T cells | Interferon gamma | Index Medicus | and Commentaries
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9. Full Text Crohn's disease‐associated polymorphism within the PTPN2 gene affects muramyl‐dipeptide‐induced cytokine secretion and autophagy
by Scharl, Michael and Mwinyi, Jessica and Fischbeck, Anne and Leucht, Katharina and Eloranta, Jyrki J and Arikkat, Joba and Pesch, Theresa and Kellermeier, Silvia and Mair, Alma and Kullak‐Ublick, Gerd A and Truninger, Kaspar and Noreen, Faiza and Regula, Jaroslaw and Gaj, Pawel and Pittet, Valerie and Mueller, Christoph and Hofmann, Claudia and Fried, Michael and McCole, Declan F and Rogler, Gerhard
Inflammatory bowel diseases, ISSN 1078-0998, 05/2012, Volume 18, Issue 5, pp. 900 - 912
Crohn's disease | NOD2 | cytokine secretion | PTPN2 polymorphism | Cytokine secretion | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Colon - cytology | Crohn Disease - genetics | RNA, Small Interfering - genetics | Adjuvants, Immunologic - pharmacology | Immunoprecipitation | Monocytes - cytology | Humans | Colon - drug effects | Male | Monocytes - metabolism | Nod2 Signaling Adaptor Protein - genetics | Autophagy | Case-Control Studies | Immunoenzyme Techniques | DNA - blood | Haplotypes - genetics | Adult | Female | Phosphorylation - drug effects | Real-Time Polymerase Chain Reaction | Signal Transduction | Interferon-gamma - secretion | RNA, Messenger - genetics | Cells, Cultured | Cytokines - secretion | Genotype | Protein Tyrosine Phosphatase, Non-Receptor Type 2 - genetics | Reverse Transcriptase Polymerase Chain Reaction | Crohn Disease - immunology | T-Box Domain Proteins - genetics | Blotting, Western | Colon - metabolism | T-Box Domain Proteins - metabolism | Acetylmuramyl-Alanyl-Isoglutamine - pharmacology | DNA - genetics | Monocytes - drug effects | Protein Tyrosine Phosphatase, Non-Receptor Type 2 - metabolism | Nod2 Signaling Adaptor Protein - metabolism | Fluorescent Antibody Technique | Protein Tyrosine Phosphatase, Non-Receptor Type 2 - antagonists & inhibitors | Polymorphism, Single Nucleotide - genetics | Mitogen-Activated Protein Kinases - genetics | Biomarkers, Tumor - genetics | Cohort Studies | Mitogen-Activated Protein Kinases - metabolism | Index Medicus
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