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by Marouli, Eirini and Graff, Mariaelisa and Medina-Gomez, Carolina and Lo, Ken Sin and Wood, Anew R and Kjaer, Troels R and Fine, Rebecca S and Lu, Yingchang and Schurmann, Claudia and Highland, Heather M and Rüeger, Sina and Thorleifsson, Gudmar and Justice, Anne E and Lamparter, David and Stirrups, Kathleen E and Turcot, Valérie and Young, Kristin L and Winkler, Thomas W and Esko, Tõnu and Karaderi, Tugce and Locke, Adam E and Masca, Nicholas G. D and Ng, Maggie C. Y and Mudgal, Poorva and Rivas, Manuel A and Vedantam, Sailaja and Mahajan, Anubha and Guo, Xiuqing and Abecasis, Goncalo and Aben, Katja K and Adair, Linda S and Alam, Dewan S and Albrecht, Eva and Allin, Kristine H and Allison, Matthew and Amouyel, Philippe and Appel, Emil V and Arveiler, Dominique and Asselbergs, Folkert W and Auer, Paul L and Balkau, Beverley and Banas, Bernhard and Bang, Lia E and Benn, Marianne and Bergmann, Sven and Bielak, Lawrence F and Blüher, Matthias and Boeing, Heiner and Boerwinkle, Eric and Böger, Carsten A and Bonnycastle, Lori L and Bork-Jensen, Jette and Bots, Michiel L and Bottinger, Erwin P and Bowden, Donald W and Brandslund, Ivan and Breen, Gerome and Brilliant, Murray H and Broer, Linda and Burt, Amber A and Butterworth, Adam S and Carey, David J and Caulfield, Mark J and Chambers, John C and Chasman, Daniel I and Chen, Yii-Der Ida and Chowdhury, Rajiv and Christensen, Cramer and Chu, Auey Y and Cocca, Massimiliano and Collins, Francis S and Cook, James P and Corley, Janie and Galbany, Jordi Corominas and Cox, Amanda J and Cuellar-Partida, Gabriel and Danesh, John and Davies, Gail and de Bakker, Paul I. W and de Borst, Gert J and de Denus, Simon and de Groot, Mark C. H and de Mutsert, Renée and Deary, Ian J and Dedoussis, George and Demerath, Ellen W and den Hollander, Anneke I and Dennis, Joe G and Di Angelantonio, Emanuele and nos, Fotios and Du, Mengmeng and Dunning, Alison M and Easton, Douglas F and Ebeling, Tapani and Edwards, Todd L and Ellinor, Patrick T and Elliott, Paul and Evangelou, Evangelos and Farmaki, Aliki-Eleni and Faul, Jessica D and ... and EPIC-CVD Consortium and GoT2D Genes Consortium and MAGIC Investigators and Global Lipids Genetics Consortium and EPIC-InterAct Consortium and ReproGen Consortium and ExomeBP Consortium and CHD Exome Consortium and T2D-Genes Consortium and The EPIC-InterAct Consortium and CHD Exome+ Consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Enheten för biobanksforskning and Allmänmedicin and Umeå universitet and Medicin
Nature, ISSN 0028-0836, 2017, Volume 542, Issue 7640, pp. 186 - 190
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2015, Volume 112, Issue 51, pp. E7128 - E7137
This paper reviews the developments that have occurred in the field of human genetics of infectious diseases from the second half of the 20th century onward.... 
Pediatrics | Immunology | Infectious diseases | Human genetics | Primary immunodeficiency | human genetics | LINKED LYMPHOPROLIFERATIVE SYNDROME | CALMETTE-GUERIN INFECTION | RECEPTOR BETA-1 DEFICIENCY | MULTIDISCIPLINARY SCIENCES | infectious diseases | ANHIDROTIC ECTODERMAL DYSPLASIA | T-CELL IMMUNODEFICIENCY | CHRONIC MUCOCUTANEOUS CANDIDIASIS | PRIMARY IMMUNODEFICIENCY DISEASES | PYOGENIC BACTERIAL-INFECTIONS | pediatrics | primary immunodeficiency | immunology | HERPES-SIMPLEX ENCEPHALITIS | INHERITED CARD9 DEFICIENCY | Encephalitis, Herpes Simplex - immunology | Humans | Genetic Diseases, Inborn - genetics | Lymphoproliferative Disorders - immunology | Mycobacterium Infections - immunology | Young Adult | Pneumococcal Infections - immunology | Mycobacterium Infections - genetics | Pneumococcal Infections - genetics | Complement System Proteins - genetics | Encephalitis, Herpes Simplex - genetics | Epidermodysplasia Verruciformis - immunology | Interferon-gamma - genetics | Immunologic Deficiency Syndromes - immunology | Child | Genetic Predisposition to Disease | Neisseria - immunology | Tinea - immunology | Infection - immunology | Candidiasis, Chronic Mucocutaneous - genetics | Malaria - immunology | Candidiasis, Chronic Mucocutaneous - immunology | Genetic Diseases, Inborn - immunology | Tinea - genetics | Epidermodysplasia Verruciformis - genetics | Lymphoproliferative Disorders - genetics | Infection - genetics | Models, Immunological | Neisseria - pathogenicity | Influenza, Human - genetics | Interferon-gamma - immunology | Adolescent | Immunologic Deficiency Syndromes - genetics | Models, Genetic | Malaria - genetics | Influenza, Human - immunology | Development and progression | Genetic aspects | Disease susceptibility | Immune response | Communicable diseases | Biological Sciences | PNAS Plus
Journal Article
PLoS Genetics, ISSN 1553-7390, 02/2010, Volume 6, Issue 2, p. e1000841
Journal Article
NATURE, ISSN 0028-0836, 02/2011, Volume 470, Issue 7333, pp. 264 - 264
Journal Article
PLoS Pathogens, ISSN 1553-7366, 11/2013, Volume 9, Issue 11, p. e1003773
Interferons (IFNs) are a group of cytokines with a well-established antiviral function. They can be induced by viral infection, are secreted and bind to... 
CELLS | DEFENSE | VIRUS-INFECTION | DISTINCT | RIG-I | MICROBIOLOGY | IRF-7 | ANTIVIRAL RESPONSE | VIROLOGY | GENE | SIGNALING PATHWAY | ADAPTER PROTEIN | PARASITOLOGY | Epithelial Cells - metabolism | Influenza A virus - genetics | Respiratory Mucosa - virology | Interferon Regulatory Factor-7 - genetics | Interferon Type I - immunology | Interferon Regulatory Factor-3 - genetics | Interleukins - metabolism | Orthomyxoviridae Infections - genetics | Respiratory Mucosa - pathology | Interleukins - genetics | Interleukins - immunology | Respiratory Mucosa - immunology | Adaptor Proteins, Signal Transducing - immunology | Interferon Type I - metabolism | Influenza A virus - immunology | Membrane Proteins - metabolism | Interferon Regulatory Factor-3 - immunology | Nerve Tissue Proteins - immunology | Membrane Proteins - genetics | Orthomyxoviridae Infections - metabolism | Epithelial Cells - pathology | Membrane Proteins - immunology | Interferon Regulatory Factor-7 - immunology | Interferon Regulatory Factor-7 - metabolism | Nerve Tissue Proteins - genetics | Mice, Knockout | Nerve Tissue Proteins - metabolism | Animals | Influenza A virus - metabolism | Epithelial Cells - immunology | Epithelial Cells - virology | Adaptor Proteins, Signal Transducing - genetics | Interferon Regulatory Factor-3 - metabolism | Interferon Type I - genetics | Mice | Respiratory Mucosa - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Orthomyxoviridae Infections - immunology | Epithelial cells | Influenza | Physiological aspects | Host-parasite relationships | Interferon | Genetic aspects | Genetic transcription | Research | Health aspects | Airway (Medicine) | Interleukins/metabolism | Nerve Tissue Proteins/immunology | Orthomyxoviridae Infections/genetics | Orthomyxoviridae Infections/metabolism | Membrane Proteins/genetics | Adaptor Proteins, Signal Transducing/genetics | Interferon Regulatory Factor-7/genetics | Interleukins/immunology | Membrane Proteins/immunology | Life Sciences | Orthomyxoviridae Infections/immunology | Influenza A virus/genetics | Nerve Tissue Proteins/metabolism | Respiratory Mucosa/immunology | Immunology | Interferon Type I/immunology | Epithelial Cells/immunology | Epithelial Cells/virology | Interferon Regulatory Factor-7/immunology | Epithelial Cells/metabolism | Interferon Regulatory Factor-3/immunology | Respiratory Mucosa/pathology | Influenza A virus/immunology | Interleukins/genetics | Interferon Regulatory Factor-3/genetics | Influenza A virus/metabolism | Adaptor Proteins, Signal Transducing/metabolism | Epithelial Cells/pathology | Adaptor Proteins, Signal Transducing/immunology | Interferon Type I/genetics | Interferon Regulatory Factor-3/metabolism | Membrane Proteins/metabolism | Nerve Tissue Proteins/genetics | Interferon Regulatory Factor-7/metabolism | Interferon Type I/metabolism | Respiratory Mucosa/metabolism | Respiratory Mucosa/virology | Cytokines | Genes | Rodents | Genomics | Genomes | Kinases | Experiments | Viral infections
Journal Article
Nature Communications, ISSN 2041-1723, 04/2015, Volume 6, Issue 1, p. 6793
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Journal of Virology, ISSN 0022-538X, 03/2018, Volume 92, Issue 6
Journal Article
PLoS genetics, ISSN 1553-7390, 2011, Volume 7, Issue 6, p. e1002128
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 04/2012, Volume 90, Issue 4, pp. 648 - 660
Systemic lupus erythematosus (SLE) is a chronic heterogeneous autoimmune disorder characterized by the loss of tolerance to self-antigens and dysregulated... 
RHEUMATOID-ARTHRITIS | GENETIC SUSCEPTIBILITY | IMMUNE-RESPONSE | RISK LOCI | CROHNS-DISEASE | VARIANTS | PRIMARY BILIARY-CIRRHOSIS | GENETICS & HEREDITY | FOLLOW-UP | FAMILIAL AGGREGATION | GENOME-WIDE ASSOCIATION | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Hispanic Americans - genetics | Membrane Proteins - genetics | Humans | Asian Continental Ancestry Group - genetics | Interferon Regulatory Factors - genetics | Male | Chromosome Mapping | Sequence Analysis, DNA | Ikaros Transcription Factor - genetics | Haplotypes - genetics | Lupus Erythematosus, Systemic - ethnology | Lupus Erythematosus, Systemic - genetics | Indians, North American - genetics | Polymorphism, Single Nucleotide - genetics | Female | African Continental Ancestry Group - genetics | Egg Proteins - genetics | Europeans | Lupus erythematosus | Genetic aspects | Research | Genetic transcription | Gene expression | Genetic regulation | Risk factors | Diseases | Lupus | Disease susceptibility | Systemic lupus erythematosus | Racially mixed people | Analysis | Haplotypes | Ikaros protein | Autoantigens | Environmental factors | Immunological tolerance | Zona pellucida | Membrane proteins | Etiology | Interleukin 1 | Replication | Zinc finger proteins | Autoimmune diseases | Gene mapping | Interferon regulatory factor | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article