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Journal Article
Nature, ISSN 0028-0836, 11/2014, Volume 515, Issue 7525, pp. 134 - 137
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 07/2013, Volume 98, Issue 7, pp. 2783 - 2790
Context: Thyroid-associated ophthalmopathy (TAO) manifests as inflammation of orbital connective tissue. Bone marrow–derived CD34+ fibrocytes infiltrate the... 
CIGARETTE-SMOKING | PROTEIN | THYROTROPIN RECEPTOR | IFN-GAMMA | DISEASE | TISSUE | ENDOCRINOLOGY & METABOLISM | ENDOPEROXIDE H SYNTHASE-2 | IL-1-BETA | INDUCTION | GRAVES OPHTHALMOPATHY | Leukocytes - pathology | Fibroblasts - secretion | Antigens, CD34 - metabolism | Orbit - immunology | Graves Ophthalmopathy - surgery | Humans | Interleukin 1 Receptor Antagonist Protein - genetics | Interleukin-1alpha - metabolism | Orbit - surgery | Interleukin-1beta - genetics | RNA, Messenger - metabolism | Cyclooxygenase 2 - biosynthesis | Leukocytes - immunology | Graves Ophthalmopathy - metabolism | Cyclooxygenase 2 - genetics | Interleukin-1beta - metabolism | Interleukin 1 Receptor Antagonist Protein - metabolism | Cell Transdifferentiation | Interleukin 1 Receptor Antagonist Protein - secretion | Interleukin-1alpha - genetics | Interleukin-1beta - biosynthesis | Orbit - pathology | Fibroblasts - metabolism | Recombinant Proteins - metabolism | Promoter Regions, Genetic | Disease Susceptibility | Cells, Cultured | Gene Expression Regulation | Fibroblasts - pathology | RNA Stability | Graves Ophthalmopathy - immunology | Orbit - metabolism | Cyclooxygenase 2 - metabolism | Fibroblasts - immunology | Interleukin-1alpha - biosynthesis | Leukocytes - secretion | Graves Ophthalmopathy - pathology | Leukocytes - metabolism | Index Medicus | Abridged Index Medicus | Endocrine Research
Journal Article
Scientific Reports, ISSN 2045-2322, 04/2017, Volume 7, Issue 1, pp. 46165 - 46165
Activation of TLR4 by lipopolysaccharide (LPS) induces both pro-inflammatory and anti-inflammatory cytokine production in macrophages. Type 4... 
CYCLIC-AMP | INHIBITION | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | SEPTIC SHOCK | LIPOPOLYSACCHARIDE | CYTOKINE | IL-1 RECEPTOR | TNF-ALPHA | HUMAN MONOCYTES | AUTOINFLAMMATORY DISEASE | Interleukin 1 Receptor Antagonist Protein - genetics | RNA Stability - drug effects | RNA, Messenger - metabolism | Interleukin 1 Receptor Antagonist Protein - blood | Interleukin-1beta - blood | Cyclic Nucleotide Phosphodiesterases, Type 4 - deficiency | Sepsis - pathology | Interleukin 1 Receptor Antagonist Protein - metabolism | Interleukin 1 Receptor Antagonist Protein - secretion | Phosphorylation - drug effects | Cyclic Nucleotide Phosphodiesterases, Type 4 - metabolism | Rolipram - pharmacology | Cyclic AMP - metabolism | Macrophages, Peritoneal - drug effects | STAT3 Transcription Factor - metabolism | Cyclic AMP-Dependent Protein Kinases - metabolism | Cell Survival - drug effects | Mice, Inbred C57BL | RNA, Messenger - genetics | Phosphodiesterase 4 Inhibitors - pharmacology | Up-Regulation - drug effects | Animals | Signal Transduction - drug effects | Cyclic AMP Response Element-Binding Protein - metabolism | Lipopolysaccharides - pharmacology | RAW 264.7 Cells | Mice | Sepsis - blood | Macrophages, Peritoneal - metabolism | Protein kinase A | Phosphorylation | Transcription | Interleukin 1 receptors | Macrophages | Lipopolysaccharides | Cell activation | Rodents | Interleukin 1 | Toll-like receptors | Phosphodiesterase | Enzymes | Cytokines | Interleukin 1 receptor antagonist | Secretion | Stat3 protein | Cyclic AMP | Inflammation | TLR4 protein | Cyclic AMP response element-binding protein | Rolipram | Isoforms | Sepsis | Peritoneum | mRNA stability | Index Medicus
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 06/2014, Volume 306, Issue 11, pp. L975 - L985
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 03/2015, Volume 308, Issue 6, pp. L495 - L502
Journal Article
Journal Article
Molecular Immunology, ISSN 0161-5890, 02/2015, Volume 63, Issue 2, pp. 521 - 529
The NLRP3 inflammasome is a macromolecular complex importantly involved in IL-1β processing. A role for this has been described in multiple sclerosis (MS). One... 
T helper cells | NLRP3 | Multiple sclerosis | Inflammasome | Th17 | VITAMIN-D | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | INTERLEUKIN-1 RECEPTOR ANTAGONIST | BIOCHEMISTRY & MOLECULAR BIOLOGY | INTERFERON-BETA | IMMUNOLOGY | HUMAN MONOCYTES | BLOOD MONONUCLEAR-CELLS | IFN-BETA | DISEASE | IL-1-BETA | CYTOKINE GM-CSF | Leukocytes, Mononuclear - metabolism | Inflammasomes - metabolism | Multiple Sclerosis - blood | Humans | Middle Aged | Male | Gene Expression Profiling | Case-Control Studies | Interleukin-1beta - blood | Adenosine Triphosphate - pharmacology | Young Adult | Cell Differentiation - genetics | Th17 Cells - drug effects | Interleukin-10 - metabolism | Adult | Female | Interleukin 1 Receptor Antagonist Protein - secretion | Th17 Cells - pathology | Interleukin-1beta - secretion | Leukocytes, Mononuclear - drug effects | Subcellular Fractions - drug effects | Vitamin D - pharmacology | Multiple Sclerosis - genetics | Down-Regulation - drug effects | Subcellular Fractions - metabolism | Inflammasomes - genetics | Gene Expression Regulation - drug effects | Interleukin-17 - metabolism | Cell Differentiation - drug effects | Lipopolysaccharides - pharmacology | Multiple Sclerosis - immunology | Th17 Cells - immunology | Neurosciences | Vitamin D | Genes | Genetic research | Calcifediol | Alfacalcidol | Gene expression | Index Medicus
Journal Article
Journal Article