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Brain Behavior and Immunity, ISSN 0889-1591, 03/2018, Volume 69, pp. 264 - 272
.... Interleukin 6 (IL-6) levels are commonly elevated in patients with depression and psychosis and in people who are at risk of developing these disorders... 
Immunopsychiatry | Interleukin 6 receptor | Interleukin 6 receptor gene | Depression | Inflammation | Mendelian randomization | ALSPAC birth cohort | IL-6 | rs2228145 | Interleukin 6 | Psychosis | Asp358Ala | IL6R | C-REACTIVE PROTEIN | METAANALYSIS | PSYCHIATRIC MORBIDITY SURVEYS | PSYCHIATRY | SCHIZOPHRENIA | MAJOR DEPRESSION | IMMUNOLOGY | CYTOKINE ALTERATIONS | NEUROSCIENCES | CORONARY-HEART-DISEASE | GENOME-WIDE ASSOCIATION | Depressive Disorder - genetics | Psychotic Disorders - diagnosis | Genetic Predisposition to Disease | Receptors, Interleukin-6 - genetics | Humans | Depressive Disorder - diagnosis | Genotype | Male | Psychotic Disorders - genetics | C-Reactive Protein - metabolism | Interleukin-6 - blood | Adolescent | Female | Polymorphism, Single Nucleotide | Child | Cohort Studies | CRP, C-Reactive Protein | IL6R, Interleukin 6 Receptor | IL-6, Interleukin 6 | CIS-R, Clinical Interview Schedule Revised | SDQ, Strengths and Difficulties Questionnaire | ELISA, Enzyme-linked Immunosorbent Assay | RCT, Randomised Controlled Trial | SNP, Single Nucleotide Polymorphism | WISC III, Wechsler Intelligence Scale for Children, 3rd edition | CHD, Coronary Heart Disease | IQ, Intelligence Quotient | ICD-10, International Classification of Diseases, 10th revision | PLIKSi, Psychosis-Like Symptom Interview | GWAS, Genome Wide Association Study | IL6R, Interleukin 6 Receptor Gene | SCAN, Schedules for Clinical Assessment in Neuropsychiatry | EPDS, Edinburgh Postnatal Depression Scale | ALSPAC, Avon Longitudinal Study of Parents and Children Birth Cohort
Journal Article
International Reviews of Immunology, ISSN 1563-5244, 2009, Volume 16, Issue 3-4, pp. 249 - 284
Ten years have passed since the molecular cloning of interleukin 6 (IL-6) in 1986. IL-6 is a typical cytokine, exhibiting functional pleiotropy and redundancy... 
Interleukin 6 | Signal transduction | STAT | Receptor | JAK | Cytokine | Receptors, Interleukin-6 - physiology | Signal Transduction - physiology | Mice | Animals | Humans | Interleukin-6 - physiology
Journal Article
Journal Article
The FASEB journal, ISSN 1530-6860, 2017, Volume 31, Issue 9, pp. 4140 - 4152
ABSTRACT IL‐6 is a pleiotropic cytokine with complex roles in inflammation and metabolic disease. The role of IL‐6 as a pro‐ or anti... 
islet | diabetes | pancreas | CHAPERONE-MEDIATED AUTOPHAGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | STAT3 | MECHANISMS | SERINE PHOSPHORYLATION | MTOR | CELL BIOLOGY | IN-VITRO | BIOLOGY | MAXIMAL ACTIVATION | MICE | INFLAMMATORY CYTOKINES | ADIPOSE-TISSUE | Cell Line | Infusion Pumps, Implantable | Glucagon-Like Peptide 1 - metabolism | Interleukin-6 - genetics | Microtubule-Associated Proteins - genetics | Signal Transduction | Microtubule-Associated Proteins - metabolism | Humans | Gene Expression Regulation | Rats | Male | Autophagy - physiology | Recombinant Proteins | Glucagon-Like Peptide 1 - genetics | Insulin-Secreting Cells - metabolism | Animals | Interleukin-6 - pharmacology | Islets of Langerhans - metabolism | Adaptor Proteins, Signal Transducing - genetics | Diabetes Mellitus, Type 2 | Mice | Apoptosis - physiology | Adaptor Proteins, Signal Transducing - metabolism | Interleukin-6 - metabolism | TOR protein | Glucagon | Chloroquine | Interleukin | Homeostasis | Lysosomes | Stimulation | AKT protein | Autophagy | Interleukin 6 | Infusion | Inhibition | Pretreatment | Pancreas | Glucagon-like peptide 1 | Stresses | Enzymes | Cell survival | Cytokines | Diabetes mellitus | Stat3 protein | Rapamycin | Inflammation | Insulin | Survival | Disease control | Stress | Signaling | Diabetes | Islets of Langerhans | Phagocytosis | Apoptosis | Research
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 139, Issue 2, pp. 462 - 471.e14
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2014, Volume 289, Issue 11, pp. 7580 - 7588
Journal Article
Journal Article
Diabetes, ISSN 0012-1797, 05/2010, Volume 59, Issue 5, pp. 1222 - 1227
OBJECTIVE Although interleukin-1 receptor antagonist (IL-1Ra) treatment is associated with improved beta-cell function and glycemic control in patients with... 
HUMAN ISLETS | OBESITY | IL-1 | GLUCOSE | URINE INHIBITOR | BETA-CELLS | ENDOCRINOLOGY & METABOLISM | RESISTANCE | INFLAMMATORY CYTOKINES | INSULIN SENSITIVITY |