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Journal Article
Blood, ISSN 0006-4971, 01/2007, Volume 109, Issue 1, pp. 155 - 158
The exact mechanism of action of IVIg in the amelioration of immune thrombocytopenic purpura (ITP) is still unclear. Studies have suggested that IVIg may... 
NITRIC-OXIDE PRODUCTION | KAWASAKI-DISEASE | FC-GAMMA RECEPTORS | ANTI-D | DENDRITIC CELLS | INFLAMMATORY DISEASES | INTRAVENOUS IMMUNOGLOBULIN | IMMUNE THROMBOCYTOPENIA | MURINE ITP | THROMBOCYTOPENIC PURPURA | HEMATOLOGY | Dendritic Cells - immunology | Recombinant Fusion Proteins - physiology | Macrophage Inflammatory Proteins - physiology | Interleukin 1 Receptor Antagonist Protein - genetics | Tumor Necrosis Factor-alpha - deficiency | Cytokines - physiology | Interleukin-10 - physiology | Purpura, Thrombocytopenic, Idiopathic - therapy | Purpura, Thrombocytopenic, Idiopathic - immunology | Receptors, Interleukin-1 - deficiency | Interleukin Receptor Common gamma Subunit - physiology | Macrophage Inflammatory Proteins - deficiency | Interleukin-4 - physiology | Macrophages - physiology | Chemokine CCL4 | Interleukin-10 - deficiency | Chemokine CCL3 | Mice, Inbred C57BL | Interleukin-4 - deficiency | Nitric Oxide - physiology | Interleukin 1 Receptor Antagonist Protein - physiology | Receptors, IgG - drug effects | Immunoglobulins, Intravenous - pharmacology | Mice, Knockout | Interleukin Receptor Common gamma Subunit - deficiency | Animals | Interleukin-12 Subunit p40 - physiology | Platelet Count | Immunoglobulins, Intravenous - therapeutic use | Interleukin-12 Subunit p40 - deficiency | Tumor Necrosis Factor-alpha - physiology | Receptors, Interleukin-1 - physiology | Mice
Journal Article
Journal of Immunology, ISSN 0022-1767, 12/2008, Volume 181, Issue 12, pp. 8237 - 8247
IL-15 is an important cytokine involved in the survival and function of CD8(+) T cells and NK cells. IL-15 can be presented by IL-15Ra (IL-15RA) to bind with... 
NATURAL-KILLER-CELLS | MARROW-DERIVED CELLS | ALPHA-CHAIN | INTERLEUKIN-15 | IN-VIVO | PROLIFERATION | OVARIAN-CANCER | IL-15R-ALPHA | IMMUNOLOGY | EXPRESSION | CUTTING EDGE | Interleukin-15 - physiology | CD8-Positive T-Lymphocytes - pathology | Ovarian Neoplasms - pathology | Killer Cells, Natural - pathology | Interleukin-15 Receptor alpha Subunit - metabolism | Interleukin-15 - biosynthesis | Signal Transduction - immunology | Lymphocyte Activation - genetics | Lymphocyte Activation - immunology | Ovarian Neoplasms - virology | Retroviridae - genetics | Antigens, Ly - biosynthesis | CD8-Positive T-Lymphocytes - metabolism | Killer Cells, Natural - immunology | Female | Growth Inhibitors - biosynthesis | Antigens, Ly - physiology | Interleukin Receptor Common gamma Subunit - physiology | Transduction, Genetic | Ovarian Neoplasms - prevention & control | Interleukin-15 Receptor alpha Subunit - physiology | Mice, Inbred C57BL | Interleukin-2 Receptor beta Subunit - physiology | Antigen Presentation - genetics | Mice, Transgenic | Interleukin-15 Receptor alpha Subunit - genetics | Signal Transduction - genetics | Interleukin Receptor Common gamma Subunit - genetics | Animals | Interleukin-15 - genetics | Interleukin-15 - metabolism | NK Cell Lectin-Like Receptor Subfamily B - biosynthesis | Cell Line, Tumor | Growth Inhibitors - physiology | Interleukin-15 Receptor alpha Subunit - biosynthesis | Mice | Killer Cells, Natural - metabolism | CD8-Positive T-Lymphocytes - immunology | NK Cell Lectin-Like Receptor Subfamily B - physiology | Ovarian Neoplasms - immunology
Journal Article
Leukemia, ISSN 0887-6924, 01/2013, Volume 27, Issue 1, pp. 66 - 74
Journal Article
Haematologica, ISSN 0390-6078, 04/2010, Volume 95, Issue 4, pp. 651 - 659
Journal Article
Molecular Therapy, ISSN 1525-0016, 12/2011, Volume 19, Issue 12, pp. 2228 - 2238
We evaluated the efficacy of structurally flexible, cationic PAMAM dendrimers as a small interfering RNA (siRNA) delivery system in a Rag2 / γc / (RAG-hu)... 
MEDICINE, RESEARCH & EXPERIMENTAL | DOUBLE-STRANDED-RNA | PAMAM DENDRIMERS | PRIMARY-CELLS | SIRNA DELIVERY | CLEAVAGE | POTENT | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PROGRESS | DISEASE | GENETICS & HEREDITY | INTERFERENCE | THERAPIES | HIV Infections - prevention & control | Leukocytes, Mononuclear - metabolism | RNA, Small Interfering - genetics | Humans | rev Gene Products, Human Immunodeficiency Virus - metabolism | Leukocytes, Mononuclear - virology | Viral Load | T-Lymphocytes, Helper-Inducer - virology | CD4-Positive T-Lymphocytes - immunology | Dendrimers | Flow Cytometry | HIV-1 - physiology | RNA, Viral - genetics | T-Lymphocytes, Helper-Inducer - immunology | tat Gene Products, Human Immunodeficiency Virus - antagonists & inhibitors | CD4-Positive T-Lymphocytes - virology | DEAD-box RNA Helicases - metabolism | Interleukin Receptor Common gamma Subunit - physiology | Disease Models, Animal | DNA-Binding Proteins - physiology | Ribonuclease III - metabolism | tat Gene Products, Human Immunodeficiency Virus - genetics | HIV Infections - genetics | HIV Infections - virology | Liver - metabolism | Viremia - genetics | Mice, Knockout | Animals | Viremia - virology | Viremia - prevention & control | Leukocytes, Mononuclear - cytology | Liver - cytology | Mice | Mice, Inbred BALB C | Nanoparticles - administration & dosage | rev Gene Products, Human Immunodeficiency Virus - genetics | rev Gene Products, Human Immunodeficiency Virus - antagonists & inhibitors | RNA, Small Interfering - administration & dosage | tat Gene Products, Human Immunodeficiency Virus - metabolism | Original
Journal Article
Journal Article
Oncotarget, ISSN 1949-2553, 2015, Volume 6, Issue 31, pp. 32039 - 32060
Cancer stem cells (CSCs) play major roles in cancer initiation, progression, and metastasis. It is evident from growing reports that PI3K/Akt/mTOR and Sonic... 
Cancer stem cell | Sonic hedgehog | PI3K/AKT/mTOR | Gli | Pancreatic cancer | BINDING PARTNER | DUCTAL ADENOCARCINOMA | MICRORNA BIOGENESIS | LIN28 | LET-7 | EPITHELIAL-MESENCHYMAL TRANSITIONS | CELL BIOLOGY | pancreatic cancer | cancer stem cell | SIGNALING PATHWAY | 3-KINASE/MAMMALIAN TARGET | sonic hedgehog | EXPRESSION | PROGRESSION | Cell Proliferation | Pancreatic Neoplasms - metabolism | TOR Serine-Threonine Kinases - metabolism | Neoplastic Stem Cells - drug effects | Humans | Hedgehog Proteins - metabolism | Epithelial-Mesenchymal Transition - drug effects | Male | Gene Expression Profiling | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Immunoenzyme Techniques | Proto-Oncogene Proteins c-akt - genetics | Pancreatic Neoplasms - drug therapy | TOR Serine-Threonine Kinases - antagonists & inhibitors | TOR Serine-Threonine Kinases - genetics | Hedgehog Proteins - genetics | Neoplastic Stem Cells - metabolism | Neoplastic Stem Cells - pathology | Female | Tumor Cells, Cultured | Interleukin Receptor Common gamma Subunit - physiology | Proto-Oncogene Proteins c-akt - metabolism | Real-Time Polymerase Chain Reaction | Pancreatic Neoplasms - pathology | RNA, Messenger - genetics | Enzyme Inhibitors - pharmacology | Hedgehog Proteins - antagonists & inhibitors | Mice, SCID | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Phosphatidylinositol 3-Kinases - genetics | Xenograft Model Antitumor Assays | Animals | Mice, Inbred NOD | Mice | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Apoptosis | Cell Movement
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2013, Volume 8, Issue 10, p. e77780
An estimated 34 million people are living with HIV worldwide (UNAIDS, 2012), with the number of infected persons rising every year. Increases in HIV prevalence... 
BLT MICE | RESPONSES | B-LYMPHOCYTE DYSFUNCTION | MULTIDISCIPLINARY SCIENCES | IN-VIVO | IMMUNODEFICIENCY-VIRUS TYPE-1 | SCID-HU MOUSE | HUMAN IMMUNE-SYSTEM | HIV-1 INFECTION | NEW-GENERATION | T-CELL EXHAUSTION | HIV Infections - prevention & control | Enzyme-Linked Immunosorbent Assay | HIV-1 - drug effects | HIV Infections - virology | Humans | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Antibodies, Blocking - pharmacology | Mice, SCID | Blotting, Western | Mice, Knockout | HIV Infections - immunology | HIV-1 - immunology | Animals | Flow Cytometry | CD8-Positive T-Lymphocytes - virology | CD8-Positive T-Lymphocytes - metabolism | Mice, Inbred NOD | Mice | Programmed Cell Death 1 Receptor - immunology | CD8-Positive T-Lymphocytes - immunology | Interleukin Receptor Common gamma Subunit - physiology | Viral Load - drug effects | Infection | Viral antibodies | Antiviral agents | Analysis | Antibodies | Monkeys | T cells | HIV (Viruses) | Health aspects | HIV infection | PD-1 protein | CD8 antigen | Liver | Chronic infection | Viruses | Lymphocytes T | Infections | CD223 antigen | Inflammatory diseases | Blood | Medical schools | Loads (forces) | Thymus | Signal transduction | Hepatitis | Receptors | Immunology | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Human immunodeficiency virus--HIV | Bone marrow | Inhibition | Immune system | Rheumatology | Melanoma | Survival | Immune response (humoral) | Augmentation | Signaling | Hospitals | Exhaustion | PD-L1 protein | Mutation | Viral infections | Cancer | Acquired immune deficiency syndrome | AIDS | HIV | Human immunodeficiency virus
Journal Article
Journal of Immunology, ISSN 0022-1767, 08/2008, Volume 181, Issue 4, pp. 2506 - 2512
Journal Article
Immunology Letters, ISSN 0165-2478, 2006, Volume 108, Issue 2, pp. 113 - 120
Abstract Cytokines of the common cytokine-receptor γ-chain (γc ) family are essential for the development and maintenance of lymphocytes. Herein, we will focus... 
Allergy and Immunology | Homeostasis | CD8 T cells | γ c cytokines | cytokines | gamma(c) cytokines | IMMUNOLOGY | MEMORY CELLS | CD8(+) T-CELLS | THYMIC STROMAL LYMPHOPOIETIN | CUTTING EDGE | RECEPTOR-DEFICIENT MICE | homeostasis | HUMAN NAIVE | MARROW-DERIVED CELLS | IN-VIVO