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Nature Immunology, ISSN 1529-2908, 07/2012, Volume 13, Issue 7, pp. 642 - 650
Journal Article
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 07/2008, Volume 205, Issue 7, pp. 1543 - 1550
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2015, Volume 195, Issue 2, pp. 672 - 682
Cardiac dysfunction is a major consequence of sepsis/septic shock and contributes to the high mortality of sepsis. Innate and inflammatory responses mediated... 
IMMUNITY | ACTIVATION | PLAYERS | ROLES | INJURY | MICE | KAPPA-B | IMMUNOLOGY | MODULATION | PROTECTS | Interleukin-1 Receptor-Associated Kinases - genetics | Myocardium - immunology | Carotid Arteries | Genetic Vectors - administration & dosage | Myocytes, Cardiac - immunology | NF-kappa B - immunology | Male | Sepsis - complications | TNF Receptor-Associated Factor 6 - antagonists & inhibitors | TNF Receptor-Associated Factor 6 - immunology | Lipopolysaccharides - antagonists & inhibitors | Heart Failure - therapy | Interleukin-1 Receptor-Associated Kinases - immunology | Heart Failure - immunology | Lentivirus - genetics | TNF Receptor-Associated Factor 6 - genetics | Heart Failure - etiology | Macrophages - immunology | Cytokines - immunology | Disease Models, Animal | NF-kappa B - antagonists & inhibitors | Sepsis - immunology | Macrophages - pathology | Signal Transduction | Mice, Inbred C57BL | Gene Expression Regulation | Heart Failure - genetics | Myocardium - pathology | Immunity, Innate | MicroRNAs - immunology | Sepsis - genetics | Myocytes, Cardiac - pathology | Administration, Intravenous | Animals | Myocytes, Cardiac - drug effects | NF-kappa B - genetics | Interleukin-1 Receptor-Associated Kinases - antagonists & inhibitors | Sepsis - therapy | Lipopolysaccharides - pharmacology | Macrophages - drug effects | Mice | MicroRNAs - genetics | Cytokines - antagonists & inhibitors | Primary Cell Culture | Cytokines - biosynthesis | microRNA-146a | NF-κB | cardiac function | TRAF6 | sepsis
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 12/2011, Volume 70, Issue 12, pp. 2207 - 2217
Objectives Interleukin-1 receptor-associated kinase (IRAK)-M suppresses Toll-like receptor (TLR)-mediated activation of innate immunity during infection. A... 
IRAK-M | GLOMERULONEPHRITIS | PATHOGENESIS | RECOGNITION | RNA | TOLERANCE | DISEASE | TOLL-LIKE RECEPTORS | MICE | RHEUMATOLOGY | INNATE IMMUNITY | T-Lymphocyte Subsets - immunology | Cell Proliferation | Interleukin-1 Receptor-Associated Kinases - genetics | Spleen - immunology | Membrane Glycoproteins - metabolism | Autoantibodies - blood | Dendritic Cells - immunology | Interleukin-1 Receptor-Associated Kinases - deficiency | Autoantibodies - biosynthesis | Signal Transduction - immunology | Lymphocyte Activation - immunology | Interleukin-1 Receptor-Associated Kinases - immunology | Lupus Erythematosus, Systemic - immunology | Autoimmune Diseases - pathology | Lupus Nephritis - pathology | Lung - pathology | Toll-Like Receptor 7 - metabolism | Mice, Inbred C57BL | Autoimmune Diseases - immunology | Cells, Cultured | Lupus Nephritis - immunology | Mice, Knockout | Animals | Lupus Erythematosus, Systemic - genetics | Mice | Toll-Like Receptor 9 - metabolism | Lupus Erythematosus, Systemic - pathology | Lung - immunology | Plasma Cells - immunology | Care and treatment | Usage | Systemic lupus erythematosus | Lymphoproliferative disorders | Toll-like receptors | Genetic aspects | Diagnosis | Lupus | Studies | Genotype & phenotype | Disease | Cytokines | Dendritic cells | Genes | Mortality | Genomes | Mutation | Kinases | Deoxyribonucleic acid--DNA
Journal Article
Cellular and Molecular Immunology, ISSN 1672-7681, 09/2011, Volume 8, Issue 5, pp. 388 - 403
Toll-like receptors (TLRs) in innate immune cells are the prime cellular sensors for microbial components. TLR activation leads to the production of... 
microRNA | innate immunity | lipopolysaccharide | LPS tolerance | Toll-like receptor | ACTIVATED PROTEIN-KINASE | COLONY-STIMULATING FACTOR | INNATE IMMUNE-SYSTEM | MONOPHOSPHORYL LIPID-A | IMMUNOLOGY | TOLL-LIKE RECEPTOR-2 | TUMOR-NECROSIS-FACTOR | SERUM-INDEPENDENT PATHWAY | RECEPTOR-ASSOCIATED KINASE | NF-KAPPA-B | MOUSE PERITONEAL-MACROPHAGES | Interleukin-1 Receptor-Associated Kinases - metabolism | Interleukin-1 Receptor-Associated Kinases - genetics | Immune System Diseases - genetics | Humans | MicroRNAs - metabolism | TNF Receptor-Associated Factor 6 - immunology | Signal Transduction - immunology | Bacteria - growth & development | Bacterial Infections - immunology | Interleukin-1 Receptor-Associated Kinases - immunology | Myeloid Differentiation Factor 88 - immunology | TNF Receptor-Associated Factor 6 - genetics | Cytokines - genetics | Bacterial Infections - microbiology | Cytokines - immunology | Cytokines - metabolism | Gene Expression Regulation - immunology | Myeloid Differentiation Factor 88 - genetics | Rats | Toll-Like Receptor 4 - genetics | Signal Transduction - genetics | Toll-Like Receptor 4 - immunology | Immunity, Innate | MicroRNAs - immunology | Toll-Like Receptor 4 - metabolism | Animals | Endotoxins - immunology | TNF Receptor-Associated Factor 6 - metabolism | Immune Tolerance - genetics | Mice | MicroRNAs - genetics | Myeloid Differentiation Factor 88 - metabolism | Endotoxins - pharmacology | Review
Journal Article