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1. Full Text The antihyperalgesic activity of a selective P2X7 receptor antagonist, A-839977, is lost in IL-1αβ knockout mice
by Honore, Prisca and Donnelly-Roberts, Diana and Namovic, Marian and Zhong, Chengmin and Wade, Carrie and Chandran, Prasant and Zhu, Chang and Carroll, William and Perez-Medrano, Arturo and Iwakura, Yoichiro and Jarvis, Michael F
Behavioural Brain Research, ISSN 0166-4328, 2009, Volume 204, Issue 1, pp. 77 - 81
The pro-inflammatory cytokine interleukin-1β (IL-1β) has been implicated in both inflammatory processes and nociceptive neurotransmission. Activation of P2X7... 
P2X7 receptors | Cytokines | Interleukin-1β | Chronic pain
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2. Full Text Prolonged Exposure to Lipopolysaccharide Induces NLRP3-Independent Maturation and Secretion of Interleukin (IL)-1β in Macrophages
by Sujeong Hong and and Je-wook Yu
Journal of Microbiology and Biotechnology, ISSN 1017-7825, 2018, Volume 28, Issue 1, pp. 115 - 121
Upon sensing of microbial infections or endogenous danger signals in macrophages, inflammasome signaling plays a significant role in triggering inflammatory... 
NLRP3 | Inflammasome | lipopolysaccharide | interleukin-1β
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3. Full Text Neuroinflammatory response in chronic hydrocephalus in juvenile rats
by Olopade, Funmilayo E and Shokunbi, M Temitayo and Azeez, Idris A and Andrioli, Anna and Scambi, Ilaria and Bentivoglio, Marina
Neuroscience, ISSN 0306-4522, 09/2019
Hydrocephalus is especially prevalent in countries with limited resources, where its treatment is still a challenge. However, long-term neuropathological... 
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4. Full Text Lack of interleukin-1ß decreases the severity of atherosclerosis in apoE-deficient mice
by Kirii, Hirokazu and Niwa, Tamikazu and Yamada, Yasuhiro and Wada, Hisayasu and Saito, Kuniaki and Iwakura, Yoichiro and Asano, Masahide and Moriwaki, Hisataka and Seishima, Mitsuru
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 04/2003, Volume 23, Issue 4, pp. 656 - 660
Interleukin-1β | Atherosclerosis | Vascular cell adhesion molecule-1 | Monocyte chemotactic protein-1
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5. Full Text Endogenous Interleukin-1β Is Implicated in Intraplaque Hemorrhage in Apolipoprotein E Gene Null Mice
by Suzuki, Etsu and Imuta, Hiroyuki and Fujita, Daishi and Takahashi, Masao and Oba, Shigeyoshi and Kiyosue, Arihiro and Nishimatsu, Hiroaki
Circulation Journal, ISSN 1346-9843, 2018
Background:Intraplaque hemorrhage (IPH) has been implicated in plaque instability and rupture in atherosclerotic lesions, although the mechanisms by which IPH... 
Matrix metalloproteinase-9 | Angiogenesis | Interleukin-1β | Intraplaque hemorrhage
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6. Inhibition Effect of IL-1β on Calcium Channels Currents in Cultured Cortical Neurons of Rat
by Zhou, Chen
08/2010
Interleukin-1β(IL-1β) is an important porinflammatory cytokine that exert wide biological functions in the central nervous system (CNS). Voltage-gated Ca2+... 
Cortical neurons | Interleukin-1β | Ca2+ currents | Patch-clamp recording
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7. Full Text Atorvastatin attenuates the production of IL-1β, IL-6, and TNF-α in the hippocampus of an amyloid β1-42-induced rat model of Alzheimer's diseaseatorvastatin attenuates the production of IL-1β, IL-6, and TNF-α in the hippocampus of an amyloid β1-42-induced rat model of Alzheimer's disease
by Zhang, Yuan-Yuan and Fan, Yu-Chen and Wang, Min and Wang, Dong and Li, Xiao-Hong
Clinical Interventions in Aging, ISSN 1176-9092, 01/2013, Volume 8, pp. 103 - 110
Inflammation | Tumor necrosis factor | Interleukin-1β | Amyloid-beta | Interleukin-6
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8. Full Text Preterm labor is induced by intraamniotic infusions of interleukin-1β and tumor necrosis factor-α but not by interleukin-6 or interleukin-8 in a nonhuman primate model
by Sadowsky, Drew W and Adams, Kristina M and Gravett, Michael G and Witkin, Steven S and Novy, Miles J
American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 2006, Volume 195, Issue 6, pp. 1578 - 1589
The purpose of this study was to determine the relative contributions of individual proinflammatory cytokines and chemokines to the triggering of preterm... 
Rhesus monkey | Cytokines | Intrauterine infection/inflammation | Interleukin-1β | Preterm labor | Tumor necrosis factor-α | Interleukin-8 | Interleukin-6
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9. Full Text β2 adrenergic receptor activation stimulates pro-inflammatory cytokine production in macrophages via PKA- and NF-κB-independent mechanisms
by Tan, Kai Soo and Nackley, Andrea G and Satterfield, Kathryn and Maixner, William and Diatchenko, Luda and Flood, Patrick M
Cellular Signalling, ISSN 0898-6568, 02/2007, Volume 19, Issue 2, pp. 251 - 260
Activation of the β adrenergic receptor (β AR) located on macrophages has been reported to possess anti-inflammatory properties, inhibiting nuclear factor κB... 
ERK1/2 | ATF-2 | p38 | Interleukin-1β | MAP kinase | ATF-1 | Interleukin-6
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10. Full Text ABCB5 maintains melanoma-initiating cells through a pro-inflammatory cytokine signaling circuit
by Wilson, Brian J and Saab, Karim R and Ma, Jie and Schatton, Tobias and Pütz, Pablo and Zhan, Qian and Murphy, George F and Gasser, Martin and Waaga-Gasser, Ana Maria and Frank, Natasha Y and Frank, Markus H
Cancer research, ISSN 0008-5472, 8/2014, Volume 74, Issue 15, pp. 4196 - 4207
The drug efflux transporter ABCB5 identifies cancer stem-like cells (CSC) in diverse human malignancies, where its expression is associated with clinical... 
CXCR1 | Interleukin-8 | Interleukin-1β | Melanoma | ABCB5
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11. Acute effects of IL-1β on sodium current in cortical neurons of rats
by Qi, Cui and Zhang, Wei-Wei and Wang, Fei and Bao, Chao-Fei and Wang, Xin-Wei and Li, Xiao-Nan and Yu, Xiao-Qing and Zhou, Chen
08/2011
Interleukin-1β (IL-1β ) is an important proinflammatory cytokine that plays a key role in injuries and diseases of the central nervous system (CNS). The... 
Voltage-dependent | Cortical neurons | Na+ currents | Interleukin-1β | Patch-clamp recording
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12. Full Text α 2 -Antiplasmin is involved in bone loss induced by ovariectomy in mice
by Shiomi, Akihito and Kawao, Naoyuki and Yano, Masato and Okada, Kiyotaka and Tamura, Yukinori and Okumoto, Katsumi and Matsuo, Osamu and Akagi, Masao and Kaji, Hiroshi
Bone, ISSN 8756-3282, 10/2015, Volume 79, pp. 233 - 241
The mechanism of postmenopausal osteoporosis is not fully understood. α 2 -Antiplasmin (α 2 -AP) is the primary inhibitor of plasmin in the fibrinolytic... 
Osteoporosis | Interleukin-1β | Estrogen | Bone | α 2 -Antiplasmin
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13. Full Text Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity
by Mitroulis, Ioannis and Ruppova, Klara and Wang, Baomei and Chen, Lan-Sun and Grzybek, Michal and Grinenko, Tatyana and Eugster, Anne and Troullinaki, Maria and Palladini, Alessandra and Kourtzelis, Ioannis and Chatzigeorgiou, Antonios and Schlitzer, Andreas and Beyer, Marc and Joosten, Leo A.B and Isermann, Berend and Lesche, Mathias and Petzold, Andreas and Simons, Kai and Henry, Ian and Dahl, Andreas and Schultze, Joachim L and Wielockx, Ben and Zamboni, Nicola and Mirtschink, Peter and Coskun, Ünal and Hajishengallis, George and Netea, Mihai G and Chavakis, Triantafyllos
Cell, ISSN 0092-8674, 01/2018, Volume 172, Issue 1-2, pp. 147 - 161.e12
Trained innate immunity fosters a sustained favorable response of myeloid cells to a secondary challenge, despite their short lifespan in circulation. We thus... 
β-glucan | trained innate immunity | inflammation | cholesterol biosynthesis | GM-CSF | innate immune memory | myelopoiesis | glycolysis | myelosuppression | interleukin-1β | LINEAGE COMMITMENT | HIGH-THROUGHPUT | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEMATOPOIETIC STEM-CELLS | QUIESCENCE | SELF-RENEWAL | GLOBAL ANALYSIS | PROLIFERATION | DIFFERENTIATION | ACCUMULATION | DORMANCY | CELL BIOLOGY | Glucose metabolism | Chemotherapy | Interleukins | Immunotherapy | Resveratrol | Hematopoietic stem cells | Cancer
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14. Full Text Immunomodulation of Human Mesenchymal Stem/Stromal Cells in Intervertebral Disc Degeneration
by Teixeira, Graciosa Q and Pereira, Catarina Leite and Ferreira, Joana R and Maia, André F and Gomez-Lazaro, Maria and Barbosa, Mário A and Neidlinger-Wilke, Cornelia and Goncalves, Raquel M
Spine, ISSN 0362-2436, 06/2018, Volume 43, Issue 12, pp. E673 - E682
intervertebral disc | mesenchymal stem/stromal cells | inflammation | organ culture | interleukin-1β
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15. Full Text Intermittent fasting prompted recovery from dextran sulfate sodium-induced colitis in mice
by Okada, Toshihiko and Otsubo, Takeshi and Hagiwara, Teruki and Inazuka, Fumika and Kobayashi, Eiko and Fukuda, Shinji and Inoue, Takuya and Higuchi, Kazuhide and Kawamura, Yuki I and Dohi, Taeko
Journal of Clinical Biochemistry and Nutrition, ISSN 0912-0009, 2017
Fasting-refeeding in mice induces transient hyperproliferation of colonic epithelial cells, which is dependent on the lactate produced as a metabolite of... 
interleukin-17 | NDRG3 | colitis | lactate | interleukin-1β
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16. Full Text The diurnal pattern of salivary IL-1β in healthy young adults
by Ghazali, Nur Basirah and Steele, Michael and Koh, David and Idris, Adi
08/2017
Disruption in circadian rhythm affects the production of inflammatory cytokines. Understanding how it behaves in diseased conditions is essential. Despite the... 
saliva | young adult | healthy | interleukin-6 | interleukin-1β
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17. Full Text Critical roles of NLRP3 inflammasome in IL-1β secretion induced by Corynebacterium pseudotuberculosis in vitro
by Zhou, Zuoyong and Zhou, Yang and Li, Xiaoxia and Li, Hexian and Li, Xiao and Tian, Shangquan and Yi, Wenyi and Yang, Haoyue and Wu, Junjun and Wu, Bi and Wang, Zhiying and Hu, Shijun and Fang, Rendong
Molecular Immunology, ISSN 0161-5890, 12/2019, Volume 116, pp. 11 - 17
is a prominent human and animal pathogen causing chronic inflammatory diseases. Interleukin-1β (IL-1β) is involved in the response to such pathogenic... 
Corynebacterium pseudotuberculosis | NF-κB | NLRP3 inflammasome | TLR4 | Interleukin-1β | p38MAPK
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18. Full Text Pro-inflammatory responses in human monocytes are β1-adrenergic receptor subtype dependent
by Grisanti, Laurel A and Evanson, Janel and Marchus, Erica and Jorissen, Heather and Woster, Andrew P and DeKrey, Wanda and Sauter, Edward R and Combs, Colin K and Porter, James E
Molecular Immunology, ISSN 0161-5890, 03/2010, Volume 47, Issue 6, pp. 1244 - 1254
Stress induced circulating catecholamines are hypothesized to selectively activate adrenergic receptors (ARs) on immunocompetent cells modulating their... 
Receptor signaling | Catecholamines | Monocytes | β-Adrenergic receptors | Interleukin-1β
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19. Full Text MiR-187-3p mimic alleviates ischemia-reperfusion-induced pain hypersensitivity through inhibiting spinal P2X7R and subsequent mature IL-1β release in mice
by Li, Xiao-Qian and Yu, Qian and Zhang, Zai-Li and Sun, Xi-Jia and Ma, Hong
Brain Behavior and Immunity, ISSN 0889-1591, 07/2019, Volume 79, pp. 91 - 101
Ischemia-reperfusion (IR)-induced pain hypersensitivity shares features of neuroinflammation and neuropathic pain, accompanied by overproduction of interleukin... 
Pain hypersensitivity | Ischemia-reperfusion injury | P2X7 purinergic receptor | Interleukin-1β | MicroRNAs
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20. Full Text The IL-1 axis is associated with airway inflammation after O3 exposure in allergic asthmatics
by Aleman, Maria M and Kesic, Matthew J and Mills, Katherine H and Peden, David B and Hernandez, Michelle L
The Journal of allergy and clinical immunology, ISSN 0091-6749, 10/2015, Volume 136, Issue 4, pp. 1099 - 1101.e2
asthma exacerbation | ozone | interleukin-1 receptor antagonist | Asthma | interleukin-1β
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