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Journal of Immunology, ISSN 0022-1767, 01/2014, Volume 192, Issue 2, pp. 623 - 629
.... Although the precise origin of the unchecked inflammatory response in obesity is unclear, it is known that overproduction of proinflammatory cytokines by innate immune cells affects metabolism... 
IMMUNE-SYSTEM | INFLAMMATION | DISEASE | RESISTANCE | FAT | AKT | IMMUNOLOGY | DIET-INDUCED OBESITY | KEY PLAYERS | ADIPOSE-TISSUE | CUTTING EDGE | Tumor Necrosis Factor-alpha - metabolism | Antigens, CD - immunology | T-Lymphocytes, Regulatory - metabolism | Epithelial Cells - metabolism | TOR Serine-Threonine Kinases - metabolism | Obesity - immunology | Insulin - immunology | Interferon-gamma - metabolism | Antigens, CD - metabolism | T-Lymphocytes, Regulatory - immunology | Epithelium - immunology | Signal Transduction - immunology | Inflammation - metabolism | Tumor Necrosis Factor-alpha - immunology | Interleukin-10 - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Receptor, Insulin - immunology | Macrophages - immunology | Hyperinsulinism - metabolism | Intra-Abdominal Fat - immunology | Transforming Growth Factor beta - immunology | Epithelium - metabolism | Mice, Inbred C57BL | Apyrase - metabolism | Cells, Cultured | Apyrase - immunology | CTLA-4 Antigen - metabolism | Inflammation - immunology | CTLA-4 Antigen - immunology | Intra-Abdominal Fat - metabolism | Obesity - metabolism | TOR Serine-Threonine Kinases - immunology | Insulin - metabolism | Macrophages - metabolism | Animals | Hyperinsulinism - immunology | Proto-Oncogene Proteins c-akt - immunology | Epithelial Cells - immunology | Interferon-gamma - immunology | Interleukin-10 - antagonists & inhibitors | Receptor, Insulin - metabolism | Mice | Interleukin-10 - immunology | Transforming Growth Factor beta - metabolism
Journal Article
Circulation research, ISSN 1524-4571, 2009, Volume 104, Issue 2, pp. e9 - e18
Persistent inflammatory response has adverse effects on left ventricular (LV) function and remodeling following acute myocardial infarction. We hypothesized... 
Myocardial infarction | Inflammation | Cardiac remodeling | Cytokines | IL-10 | CARDIAC-FUNCTION | CHRONIC HEART-FAILURE | CARDIAC & CARDIOVASCULAR SYSTEMS | ANGIOGENESIS | NITRIC-OXIDE SYNTHASE | myocardial infarction | INTERLEUKIN-10 | FACTOR-ALPHA | MATRIX METALLOPROTEINASES | TUMOR-NECROSIS-FACTOR | inflammation | cardiac remodeling | PERIPHERAL VASCULAR DISEASE | cytokines | DYSFUNCTION | HEMATOLOGY | EXPRESSION | ELAV-Like Protein 1 | NIH 3T3 Cells | RNA-Binding Proteins - genetics | Phosphorylation | Vascular Endothelial Growth Factor A - metabolism | RNA, Messenger - metabolism | Anti-Inflammatory Agents - metabolism | ELAV Proteins | Inflammation - metabolism | Matrix Metalloproteinase 9 - metabolism | RNA Interference | Time Factors | Matrix Metalloproteinase 9 - genetics | Myocardial Infarction - pathology | Myocardium - metabolism | Inflammation Mediators - metabolism | Interleukin-10 - administration & dosage | Antigens, Surface - metabolism | Interleukin-10 - metabolism | Anti-Inflammatory Agents - administration & dosage | Myocardial Infarction - physiopathology | p38 Mitogen-Activated Protein Kinases - metabolism | Capillaries - metabolism | STAT3 Transcription Factor - metabolism | Disease Models, Animal | Recombinant Proteins - metabolism | Mice, Inbred C57BL | Ventricular Function, Left - drug effects | Antigens, Surface - genetics | Myocardium - pathology | Myocardial Infarction - metabolism | Animals | Arterioles - metabolism | Fibrosis | Inflammation - prevention & control | Mice | Ventricular Remodeling - drug effects | Neovascularization, Physiologic | RNA-Binding Proteins - metabolism | Apoptosis | Inflammation - physiopathology | RNA, Small Interfering - metabolism
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2017, Volume 356, Issue 6337, pp. 513 - 519
Journal Article
Nature immunology, ISSN 1529-2916, 2012, Volume 14, Issue 2, pp. 162 - 171
Signaling through the G protein-coupled receptors for the complement fragments C3a and C5a (C3aR and C5aR, respectively) by dendritic cells and CD4(+) cells... 
Forkhead Transcription Factors - immunology | Cell Communication - immunology | T-Lymphocytes, Regulatory - metabolism | TOR Serine-Threonine Kinases - metabolism | Transforming Growth Factor beta1 - metabolism | Complement C5a - metabolism | Receptors, Complement - metabolism | T-Lymphocytes, Regulatory - immunology | Signal Transduction - immunology | Transforming Growth Factor beta1 - immunology | Forkhead Transcription Factors - metabolism | Class Ib Phosphatidylinositol 3-Kinase - metabolism | T-Lymphocytes, Regulatory - cytology | Interleukin-10 - metabolism | Receptor, Anaphylatoxin C5a - immunology | Cell Differentiation | Proto-Oncogene Proteins c-akt - metabolism | Complement C3a - metabolism | Interleukin-6 - metabolism | Cyclic AMP-Dependent Protein Kinases - metabolism | Receptors, Chemokine - metabolism | Gene Expression Regulation | Mice, Transgenic | Receptors, Chemokine - immunology | Receptor Cross-Talk - immunology | TOR Serine-Threonine Kinases - immunology | Animals | Proto-Oncogene Proteins c-akt - immunology | Receptors, Complement - immunology | Cyclic AMP-Dependent Protein Kinases - immunology | Interleukin-6 - immunology | Mice | Complement C3a - immunology | Complement C5a - immunology | Class Ib Phosphatidylinositol 3-Kinase - immunology | Interleukin-10 - immunology | Receptor, Anaphylatoxin C5a - metabolism
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 2006, Volume 116, Issue 4, pp. 916 - 928
Journal Article
Nature immunology, ISSN 1529-2916, 2005, Volume 6, Issue 8, pp. 777 - 784
Journal Article
The FASEB Journal, ISSN 0892-6638, 11/2005, Volume 19, Issue 13, pp. 1890 - 1892
ABSTRACTWe investigated a possible beneficial role for bilirubin, one of the products of heme degradation by the cytoprotective enzyme heme oxygenase‐1 in... 
nitric oxide | oxygen free radicals | OXIDATIVE STRESS | SUPEROXIDE | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | INDUCTION | BILIVERDIN | CELL BIOLOGY | SYNTHASE EXPRESSION | ANTIOXIDANT | IN-VIVO | BIOLOGY | HEME OXYGENASE-1 | SERUM BILIRUBIN | Nitric Oxide Synthase Type II - biosynthesis | Bilirubin - metabolism | Antioxidants - metabolism | Kidney - enzymology | Malondialdehyde - chemistry | NADPH Oxidases - metabolism | Male | Aorta - metabolism | Kidney - metabolism | Time Factors | Myocardium - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Interleukin-6 - metabolism | Glutathione Peroxidase - metabolism | Free Radicals | Down-Regulation | NADPH Oxidases - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Rats | Rats, Sprague-Dawley | Blotting, Western | Nitrates - metabolism | Macrophages - metabolism | Rats, Gunn | Models, Biological | Lipopolysaccharides - chemistry | Mice | Nitric Oxide Synthase - metabolism | Blood Pressure | Jaundice - pathology | Tumor Necrosis Factor-alpha - metabolism | Nitric Oxide Synthase Type II - chemistry | Nitrites - metabolism | Shock, Septic - prevention & control | Oxygen - metabolism | Shock, Septic - metabolism | Heme - chemistry | Escherichia coli - metabolism | Shock, Septic - drug therapy | Interleukin-10 - metabolism | Aorta - enzymology | Superoxide Dismutase - metabolism | Cell Line | Bilirubin - chemistry | Models, Statistical | Homozygote | Myocardium - enzymology | Animals | Nitric Oxide - metabolism
Journal Article
Journal Article
Nature immunology, ISSN 1529-2916, 2017, Volume 18, Issue 12, pp. 1332 - 1341
Journal Article
BMC gastroenterology, ISSN 1471-230X, 2016, Volume 16, Issue 1, p. 40
Background: Breastfeeding is associated with a variety of positive health outcomes in children and is recommended exclusively for the first 6 months of life;... 
Peyer's patches | GALT | Jejunum | Nutrition | Ileum | PIGS | EARLY INFANCY | PERMEABILITY | BARRIER | ENVIRONMENT | COLONIZATION | GUT MICROBIOTA | HUMAN-MILK | IMMUNE-RESPONSES | GASTROENTEROLOGY & HEPATOLOGY | Interleukin-8 - genetics | Up-Regulation | Jejunum - pathology | Cadherins - metabolism | Calcium - metabolism | Humans | Ileum - metabolism | Interleukin-8 - drug effects | Leukemia Inhibitory Factor - genetics | Vascular Endothelial Growth Factor A - metabolism | Peyer's Patches - drug effects | RNA, Messenger - metabolism | Vascular Endothelial Growth Factor A - genetics | Antigens, CD - genetics | Antigens, CD - metabolism | Jejunum - metabolism | Leukemia Inhibitory Factor - metabolism | Jejunum - drug effects | Fas Ligand Protein - drug effects | Ileum - drug effects | Swine | Interleukin-8 - metabolism | Cadherins - genetics | Soy Foods | Cytokines - genetics | Interleukin-6 - metabolism | Infant, Newborn | Milk | Animals, Newborn | Interleukin-6 - genetics | Down-Regulation | Interleukin-27 - genetics | Gastrointestinal Microbiome - drug effects | Diet | Interleukin-10 - genetics | Interleukin-15 - metabolism | Intestine, Small - metabolism | Peyer's Patches - immunology | Fas Ligand Protein - genetics | Fas Ligand Protein - metabolism | Ileum - pathology | Interferon-alpha - drug effects | Intestine, Small - pathology | Interferon-alpha - genetics | Interleukin-10 - metabolism | Interleukin-9 - metabolism | Vascular Endothelial Growth Factor A - drug effects | Interleukin-27 - metabolism | RNA, Messenger - drug effects | Interferon-alpha - metabolism | Cytokines - metabolism | Intestine, Small - microbiology | Jejunum - microbiology | Infant Formula - pharmacology | Animals | Interleukin-15 - genetics | Cytokines - drug effects | Interleukin-9 - genetics | Intestine, Small - drug effects | Leukemia Inhibitory Factor - drug effects | Ileum - microbiology | Interleukin-10 | Analysis | Influence | Research | Gene expression | Breast feeding | Health aspects
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2013, Volume 339, Issue 6126, pp. 1448 - 1453
Type I interferons (IFN-α and IFN-β) are important for protection against many viral infections, whereas type II interferon (IFN-γ) is essential for host... 
Monocytes | Messenger RNA | Tuberculosis | Mycobacterium tuberculosis | Antimicrobials | REPORTS | Leprosy | Infections | Skin | Lesions | Gene expression | LISTERIA-MONOCYTOGENES | ACTIVATION | PROFILES | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | HUMAN TUBERCULOSIS | IL-1-BETA | INDUCTION | DEPENDENT ANTIMICROBIAL PATHWAY | SARCOIDOSIS | LEPROSY | Up-Regulation | Interferon-beta - immunology | Humans | Transcriptome | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - genetics | Monocytes - metabolism | Monocytes - immunology | Interferon-gamma - metabolism | Antimicrobial Cationic Peptides - metabolism | RNA, Messenger - metabolism | Receptors, Calcitriol - genetics | Mycobacterium leprae - immunology | Interferon-beta - genetics | Interleukin-10 - metabolism | beta-Defensins - metabolism | Interferon-gamma - genetics | Antimicrobial Cationic Peptides - genetics | Leprosy, Lepromatous - genetics | Mycobacterium leprae - physiology | Leprosy, Tuberculoid - immunology | beta-Defensins - genetics | Leprosy, Lepromatous - immunology | RNA, Messenger - genetics | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - metabolism | Microbial Viability | Receptors, Calcitriol - metabolism | Leprosy, Tuberculoid - genetics | Tuberculosis - immunology | Leprosy, Lepromatous - metabolism | Interferon-beta - metabolism | Tuberculosis - genetics | Leprosy, Tuberculoid - metabolism | Interferon-gamma - immunology | Interleukin-10 - genetics | Interleukins | Physiological aspects | Host-parasite relationships | Anti-infective agents | Interferon | Genetic aspects | Health aspects | Antimicrobial agents | Pathogenesis | Genes | Bacteria | Human behavior | Antiinfectives and antibacterials | Digital signatures
Journal Article