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by Marouli, Eirini and Graff, Mariaelisa and Medina-Gomez, Carolina and Lo, Ken Sin and Wood, Anew R and Kjaer, Troels R and Fine, Rebecca S and Lu, Yingchang and Schurmann, Claudia and Highland, Heather M and Rüeger, Sina and Thorleifsson, Gudmar and Justice, Anne E and Lamparter, David and Stirrups, Kathleen E and Turcot, Valérie and Young, Kristin L and Winkler, Thomas W and Esko, Tõnu and Karaderi, Tugce and Locke, Adam E and Masca, Nicholas G. D and Ng, Maggie C. Y and Mudgal, Poorva and Rivas, Manuel A and Vedantam, Sailaja and Mahajan, Anubha and Guo, Xiuqing and Abecasis, Goncalo and Aben, Katja K and Adair, Linda S and Alam, Dewan S and Albrecht, Eva and Allin, Kristine H and Allison, Matthew and Amouyel, Philippe and Appel, Emil V and Arveiler, Dominique and Asselbergs, Folkert W and Auer, Paul L and Balkau, Beverley and Banas, Bernhard and Bang, Lia E and Benn, Marianne and Bergmann, Sven and Bielak, Lawrence F and Blüher, Matthias and Boeing, Heiner and Boerwinkle, Eric and Böger, Carsten A and Bonnycastle, Lori L and Bork-Jensen, Jette and Bots, Michiel L and Bottinger, Erwin P and Bowden, Donald W and Brandslund, Ivan and Breen, Gerome and Brilliant, Murray H and Broer, Linda and Burt, Amber A and Butterworth, Adam S and Carey, David J and Caulfield, Mark J and Chambers, John C and Chasman, Daniel I and Chen, Yii-Der Ida and Chowdhury, Rajiv and Christensen, Cramer and Chu, Auey Y and Cocca, Massimiliano and Collins, Francis S and Cook, James P and Corley, Janie and Galbany, Jordi Corominas and Cox, Amanda J and Cuellar-Partida, Gabriel and Danesh, John and Davies, Gail and de Bakker, Paul I. W and de Borst, Gert J and de Denus, Simon and de Groot, Mark C. H and de Mutsert, Renée and Deary, Ian J and Dedoussis, George and Demerath, Ellen W and den Hollander, Anneke I and Dennis, Joe G and Di Angelantonio, Emanuele and nos, Fotios and Du, Mengmeng and Dunning, Alison M and Easton, Douglas F and Ebeling, Tapani and Edwards, Todd L and Ellinor, Patrick T and Elliott, Paul and Evangelou, Evangelos and Farmaki, Aliki-Eleni and Faul, Jessica D and ... and EPIC-CVD Consortium and GoT2D Genes Consortium and MAGIC Investigators and Global Lipids Genetics Consortium and EPIC-InterAct Consortium and ReproGen Consortium and ExomeBP Consortium and CHD Exome Consortium and T2D-Genes Consortium and CHD Exome+ Consortium and The EPIC-InterAct Consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Enheten för biobanksforskning and Allmänmedicin and Umeå universitet and Medicin
Nature, ISSN 0028-0836, 2017, Volume 542, Issue 7640, pp. 186 - 190
Height is a highly heritable, classic polygenic trait with approximately 700 common associated variants identified through genome-wide association studies so... 
MULTIDISCIPLINARY SCIENCES | MISSING HERITABILITY | GENETIC ARCHITECTURE | INTERLEUKIN-11 | MICE | MUTATIONS | GENOME-WIDE ASSOCIATION | Cell Adhesion Molecules - genetics | Gene Frequency - genetics | Humans | Glycoproteins - metabolism | Male | Intercellular Signaling Peptides and Proteins - metabolism | Hedgehog Proteins - genetics | Proteolysis | NADPH Oxidases - genetics | Adult | Female | Interleukin-11 Receptor alpha Subunit - genetics | Somatomedins - metabolism | Glycosaminoglycans - biosynthesis | Glycoproteins - genetics | Multifactorial Inheritance - genetics | Procollagen N-Endopeptidase - genetics | Intercellular Signaling Peptides and Proteins - genetics | Interferon Regulatory Factors - genetics | Proteoglycans - biosynthesis | NADPH Oxidase 4 | Body Height - genetics | Genome, Human - genetics | Phenotype | Receptors, Androgen - genetics | Alleles | Genetic Variation - genetics | Pregnancy-Associated Plasma Protein-A - metabolism | ADAMTS Proteins - genetics | Stature | Genetic aspects | Observations | Genetic variation | Studies | Datasets | Disease | Genes | Deoxyribonucleic acid--DNA | Index Medicus | Hälsovetenskaper | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Medical and Health Sciences | Medicin och hälsovetenskap | Public Health, Global Health, Social Medicine and Epidemiology | Health Sciences
Journal Article
by Lanktree, Matthew B and Guo, Yiran and Murtaza, Muhammed and Glessner, Joseph T and Bailey, Swneke D and Bailey, Kristian M and Onland-Moret, N. Charlotte and Lettre, Guillaume and Ongen, Halit and Rajagopalan, Ramakrishnan and Johnson, W. Craig and Johnson, Toby and Johnson, Julie A and Shen, Haiqing and Nelson, Christopher P and Klopp, Norman and Baumert, Jens and Padmanabhan, Sandosh and Pankratz, Nathan and Pankow, James S and Shah, Sonia and Taylor, Kira and Barnard, John and Peters, Bas J and M. Maloney, Cliona and Lobmeyer, Maximilian T and Stanton, Alice and Zafarmand, M. Hadi and Romaine, Simon P.R and Mehta, Amar and van Iperen, Erik P.A and Gong, Yan and Price, Tom S and Smith, George Davey and Smith, Erin N and Kim, Cecilia E and Li, Mingyao and Li, Qing and Li, Yun R and Asselbergs, Folkert W and Atwood, Larry D and Bhatt, Deepak and Bauer, Florianne and Behr, Elijah R and Bhangale, Tushar and Boer, Jolanda M.A and Boer, Anthonius de and Boehm, Bernhard O and Bradfield, Jonathan P and Brown, Morris and Braund, Peter S and Burton, Paul R and Carty, Cara and Chandrupatla, Hareesh R and Chen, Wei and Connell, John and Dalgeorgou, Chrysoula and Drenos, Fotios and Elbers, Clara C and Fang, James C and Fox, Caroline S and Frackelton, Edward C and Fuchs, Barry and Furlong, Clement E and Gibson, Quince and Gieger, Christian and Goel, Anuj and Grobbee, Diederik E and Hastie, Claire and Howard, Philip J and Huang, Guan-Hua and Kleber, Marcus E and Klein, Ronald and Klein, Barbara E.K and Kooperberg, Charles and Ky, Bonnie and LaCroix, Andrea and Lanken, Paul and Lathrop, Mark and Marshall, Vanessa and Melander, Olle and Mentch, Frank D and J. Meyer, Nuala and Monda, Keri L and Montpetit, Alexandre and Murugesan, Gurunathan and Nakayama, Karen and Nondahl, Dave and Onipinla, Abiodun and Rafelt, Suzanne and Newhouse, Stephen J and Otieno, F. George and Patel, Sanjey R and Putt, Mary E and Rodriguez, Santiago and Safa, Radwan N and Sawyer, Douglas B and Schreiner, Pamela J and Simpson, Claire and Sivapalaratnam, Suthesh and ... and PROCARDIS and Whitehall II Study and WHII 50K Grp and Hugh Watkins on behalf of PROCARDIS and Meena Kumari on behalf of the Whitehall II Study and the WHII 50K Group
The American Journal of Human Genetics, ISSN 0002-9297, 01/2011, Volume 88, Issue 1, pp. 6 - 18
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, pp. e64845 - e64845
Background: The toll-like receptor (TLR) 4-interleukin1 beta (IL1 beta) signaling pathway is involved in the monosodium urate (MSU)-mediated inflammation. The... 
HYPERURICEMIA | VARIANTS | MULTIDISCIPLINARY SCIENCES | DISEASE | QUANTITATIVE PCR | MICE | PREVALENCE | Leukocytes, Mononuclear - metabolism | Hyperuricemia - pathology | Globulins - metabolism | Humans | Middle Aged | Male | Arthritis, Gouty - genetics | RNA, Messenger - metabolism | Case-Control Studies | Interleukin-1beta - blood | Ethnic Groups - genetics | Interleukin-11 - blood | Female | Genetic Predisposition to Disease - genetics | RNA, Messenger - genetics | Toll-Like Receptor 4 - genetics | Interleukin-11 - metabolism | Signal Transduction - genetics | Toll-Like Receptor 4 - metabolism | Asian Continental Ancestry Group - ethnology | Hyperuricemia - genetics | Hyperuricemia - blood | Arthritis, Gouty - pathology | Arthritis, Gouty - blood | Polymorphism, Single Nucleotide | RNA | Genes | Genetic research | Arthritis | Genetic aspects | Inflammation | Single nucleotide polymorphisms | Glaucoma | Laboratories | Cardiovascular disease | Lipids | Leukocytes (mononuclear) | mRNA | Single-nucleotide polymorphism | Family medical history | Dermatitis | Gene polymorphism | Proteins | Signal transduction | Immunology | Interleukin 1 | Toll-like receptors | Peripheral blood mononuclear cells | Rheumatism | Lipid metabolism | Genotypes | Immune system | Rheumatology | Uric acid | TLR4 protein | Metabolism | Gene expression | Patients | Asthma | Crohns disease | Inflammatory bowel disease | Immune systems | Studies | Signaling | Hospitals | Rheumatoid arthritis | Sepsis | Prostate cancer | Polymorphism | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, pp. 1393 - 1393
Journal Article
Cell Reports, ISSN 2211-1247, 02/2016, Volume 14, Issue 7, pp. 1761 - 1773
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 02/2017, Volume 23, Issue 4, pp. 1091 - 1103
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, pp. e0180834 - e0180834
Patients with Ulcerative Colitis (UC) have an increased risk to develop colitis-associated colorectal cancer (CAC). Here, we found that protein expression of... 
MULTIDRUG-RESISTANT CELLS | COLORECTAL-CANCER RISK | COLON-CANCER | INTESTINAL INFLAMMATION | INFLAMMATORY-BOWEL-DISEASE | NEOPLASTIC PROGRESSION | MULTIDISCIPLINARY SCIENCES | ULCERATIVE-COLITIS | HUMAN B-CELLS | P-GLYCOPROTEIN EXPRESSION | PLATELET-ACTIVATING-FACTOR | Epiregulin - immunology | ATP Binding Cassette Transporter, Sub-Family B - deficiency | Colorectal Neoplasms - genetics | Humans | Colitis, Ulcerative - genetics | Gene Expression Regulation, Neoplastic | Male | Monocyte Chemoattractant Proteins - immunology | Colitis, Ulcerative - immunology | DNA-Binding Proteins - deficiency | Leukocyte Common Antigens - immunology | Cyclooxygenase 2 - genetics | Intestinal Mucosa - immunology | ATP Binding Cassette Transporter, Sub-Family B - immunology | B-Lymphocytes - pathology | Cyclooxygenase 2 - immunology | Disease Models, Animal | Colitis, Ulcerative - complications | DNA-Binding Proteins - immunology | Signal Transduction | Carcinogenesis - immunology | Genes, Immunoglobulin Light Chain - genetics | Carcinogenesis - genetics | Interleukin-11 - genetics | Colitis, Ulcerative - pathology | TNF-Related Apoptosis-Inducing Ligand - immunology | DNA-Binding Proteins - genetics | Epiregulin - genetics | Chemotaxis | Mice, Knockout | Carcinogenesis - pathology | Monocyte Chemoattractant Proteins - genetics | Animals | B-Lymphocytes - immunology | Colorectal Neoplasms - immunology | Leukocyte Common Antigens - genetics | Colorectal Neoplasms - complications | Interleukin-11 - immunology | Mice | Colorectal Neoplasms - pathology | ATP Binding Cassette Transporter, Sub-Family B - genetics | TNF-Related Apoptosis-Inducing Ligand - genetics | Intestinal Mucosa - pathology | Patient outcomes | Colorectal cancer | Development and progression | Research | B cells | Gene expression | Health aspects | Risk factors | Ulcerative colitis | Protein binding | Cell culture | Mucosa | Proteins | Tumorigenesis | Light levels | Damage | Interleukin 11 | Glycoproteins | Patients | Inflammatory bowel disease | Injury prevention | Hospitals | B220 antigen | DNA microarrays | Cell injury | Ligands | Animal models | Inflammatory bowel diseases | Colorectal carcinoma | Genes | Inflammatory response | Carcinogenesis | Medical schools | Carcinogens | Colon cancer | Lymphocytes | Intestine | Rodents | Hepatology | Gastroenterology | Colon | Dysplasia | Immune response | CD19 antigen | Multidrug resistance | Health risks | Inflammation | Spheroids | Lymphocytes B | Cell death | Cyclooxygenase-2 | ATP | Chemokines | Tumors | Cancer | Apoptosis | Index Medicus
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 07/2011, Volume 89, Issue 1, pp. 67 - 81
Journal Article