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1. Full Text Distinct pathways of humoral and cellular immunity induced with the mucosal administration of a nanoemulsion adjuvant
by Bielinska, Anna U and Makidon, Paul E and Janczak, Katarzyna W and Blanco, Luz P and Swanson, Benjamin and Smith, Douglas M and Pham, Tiffany and Szabo, Zsuzsanna and Kukowska-Latallo, Jolanta F and Baker Jr, James R
The Journal of immunology (1950), ISSN 0022-1767, 03/2014, Volume 192, Issue 6, pp. 2722 - 2733
Life Sciences & Biomedicine | Immunology | Science & Technology | Adjuvants, Immunologic - administration & dosage | Adjuvants, Immunologic - pharmacology | Oligonucleotide Array Sequence Analysis | Immunity, Humoral - immunology | Interleukin-12 - genetics | Dendritic Cells - immunology | Humans | NF-kappa B - immunology | NF-kappa B - metabolism | Transcriptome - immunology | Emulsions - pharmacology | Signal Transduction - immunology | Immunity, Cellular - drug effects | Emulsions - administration & dosage | HEK293 Cells | Interleukin-12 Receptor beta 1 Subunit - genetics | Myeloid Differentiation Factor 88 - immunology | Dendritic Cells - drug effects | Female | Toll-Like Receptors - metabolism | Interleukin-12 Receptor beta 1 Subunit - metabolism | Dendritic Cells - metabolism | Cell Line | Immunity, Cellular - genetics | Immunity, Humoral - genetics | Mice, Inbred C57BL | Toll-Like Receptors - immunology | Cells, Cultured | Myeloid Differentiation Factor 88 - genetics | Interleukin-12 - metabolism | Signal Transduction - genetics | Transcriptome - drug effects | Transcriptome - genetics | Reverse Transcriptase Polymerase Chain Reaction | Administration, Intranasal | Mice, Knockout | Immunity, Cellular - immunology | Animals | Signal Transduction - drug effects | Toll-Like Receptors - genetics | Interleukin-12 - immunology | Immunity, Humoral - drug effects | Mice | Interleukin-12 Receptor beta 1 Subunit - immunology | Myeloid Differentiation Factor 88 - metabolism | Index Medicus | Abridged Index Medicus | Immunotherapy and Vaccines
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2. Full Text Safety and Comparative Immunogenicity of an HIV-1 DNA Vaccine in Combination with Plasmid Interleukin 12 and Impact of Intramuscular Electroporation for Delivery
by Spyros A. Kalams and Scott D. Parker and Marnie Elizaga and Barbara Metch and Srilatha Edupuganti and John Hural and Stephen De Rosa and Donald K. Carter and Kyle Rybczyk and Ian Frank and Jonathan Fuchs and Beryl Koblin and Denny H. Kim and Patrice Joseph and Michael C. Keefer and Lindsey R. Baden and John Eldridge and Jean Boyer and Adam Sherwat and Massimo Cardinali and Mary Allen and Michael Pensiero and Chris Butler and Amir S. Khan and Jian Yan and Niranjan Y. Sardesai and James G. Kublin and David B. Weiner and NIAID HIV Vaccine Trials Network and the NIAID HIV Vaccine Trials Network
The Journal of infectious diseases, ISSN 0022-1899, 9/2013, Volume 208, Issue 5, pp. 818 - 829
T lymphocytes | HIV/AIDS | Body mass index | Immune response | HIV | Interleukins | Plasmids | Vaccination | Electroporation | DNA vaccines | HIV 1 | plasmid cytokine adjuvant | electroporation | vaccination | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Miscellaneous | Infectious diseases | Biological and medical sciences | Medical sciences | Virology | Adjuvants, Immunologic - administration & dosage | Interleukin-12 - genetics | Humans | Middle Aged | AIDS Vaccines - immunology | Male | DNA - adverse effects | AIDS Vaccines - adverse effects | CD4-Positive T-Lymphocytes - immunology | Young Adult | Vaccination - methods | Adjuvants, Immunologic - genetics | Adult | Female | Drug Administration Routes | DNA - immunology | DNA - administration & dosage | HIV-1 - genetics | HIV-1 - immunology | Interleukin-12 - administration & dosage | Adolescent | AIDS Vaccines - administration & dosage | CD8-Positive T-Lymphocytes - immunology | Cytokines - biosynthesis | Usage | AIDS vaccines | Interleukin-12 | Dosage and administration | Research | Human immunogenetics | Index Medicus | Abridged Index Medicus | Major and Brief Reports
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3. Full Text Regression of prostate tumors after intravenous administration of lactoferrin-bearing polypropylenimine dendriplexes encoding TNF-α, TRAIL, and interleukin-12
by Altwaijry, Najla and Somani, Sukrut and Parkinson, John A and Tate, Rothwelle J and Keating, Patricia and Warzecha, Monika and Mackenzie, Graeme R and Leung, Hing Y and Dufès, Christine
Drug delivery, ISSN 1071-7544, 01/2018, Volume 25, Issue 1, pp. 679 - 689
lactoferrin | gene therapy | nanoparticles | Prostate cancer | dendrimer | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | TNF-Related Apoptosis-Inducing Ligand - administration & dosage | Interleukin-12 - genetics | Humans | Tumor Necrosis Factor-alpha - genetics | Male | Xenograft Model Antitumor Assays - methods | Lactoferrin - administration & dosage | Prostatic Neoplasms - therapy | Administration, Intravenous | Animals | Interleukin-12 - administration & dosage | Prostatic Neoplasms - genetics | Cell Line, Tumor | Tumor Necrosis Factor-alpha - administration & dosage | Mice | Mice, Inbred BALB C | Polypropylenes - administration & dosage | TNF-Related Apoptosis-Inducing Ligand - genetics | Genetic Therapy - methods | Gene therapy | Tumors | Index Medicus | prostate cancer
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4. Full Text Oral administration of Euglena gracilis Z and its carbohydrate storage substance provides survival protection against influenza virus infection in mice
by Nakashima, Ayaka and Suzuki, Kengo and Asayama, Yuta and Konno, Makoto and Saito, Keita and Yamazaki, Noriyuki and Takimoto, Hiroaki
Biochemical and biophysical research communications, ISSN 0006-291X, 12/2017, Volume 494, Issue 1-2, pp. 379 - 383
Euglena gracilis Z | Influenza virus | Interferon-γ | Paramylon | β-1, 3-D-glucan | Interleukin-12 | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Adjuvants, Immunologic - administration & dosage | Influenza A Virus, H1N1 Subtype - growth & development | Glucans - administration & dosage | Lung - virology | Female | Interleukin-1beta - biosynthesis | Euglena gracilis - chemistry | Interleukin-12 - biosynthesis | Administration, Oral | Euglena gracilis - immunology | Interleukin-1beta - immunology | Influenza A Virus, H1N1 Subtype - pathogenicity | Orthomyxoviridae Infections - diet therapy | Influenza A Virus, H1N1 Subtype - drug effects | Animals | Orthomyxoviridae Infections - mortality | Interferon-gamma - immunology | Lung - drug effects | Interleukin-12 - immunology | Interleukin-6 - immunology | Survival Analysis | Interleukin-6 - biosynthesis | Interleukin-10 - biosynthesis | Mice | Mice, Inbred BALB C | Dietary Supplements | Interleukin-10 - immunology | Orthomyxoviridae Infections - virology | Interferon-gamma - biosynthesis | Lung - immunology | Orthomyxoviridae Infections - immunology | Influenza viruses | Interleukins | Influenza | Dietary supplements | Interferon | Biological response modifiers | Health aspects | Index Medicus
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5. Full Text Comparison of Ustekinumab and Etanercept for Moderate-to-Severe Psoriasis
by Griffiths, Christopher E.M and Strober, Bruce E and van de Kerkhof, Peter and Ho, Vincent and Fidelus-Gort, Roseanne and Yeilding, Newman and Guzzo, Cynthia and Xia, Yichuan and Zhou, Bei and Li, Shu and Dooley, Lisa T and Goldstein, Neil H and Menter, Alan and ACCEPT Study Grp and ACCEPT Study Group
The New England journal of medicine, ISSN 0028-4793, 01/2010, Volume 362, Issue 2, pp. 118 - 128
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Dermatology | Psoriasis. Parapsoriasis. Lichen | Severity of Illness Index | Psoriasis - drug therapy | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Immunologic Factors - administration & dosage | Immunoglobulin G - therapeutic use | Ustekinumab | Antibodies, Monoclonal - therapeutic use | Male | Receptors, Tumor Necrosis Factor - administration & dosage | Immunoglobulin G - administration & dosage | Receptors, Tumor Necrosis Factor - therapeutic use | Antibodies, Monoclonal, Humanized | Etanercept | Antibodies, Monoclonal - administration & dosage | Interleukin-23 - antagonists & inhibitors | Interleukin-12 - antagonists & inhibitors | Adult | Female | Immunosuppressive Agents - administration & dosage | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Immunologic Factors - therapeutic use | Dosage and administration | Psoriasis | Comparative analysis | Drug therapy | Fees & charges | Cytokines | Stock options | Laboratories | Research & development--R&D | Equity | Interleukin 23 | Interleukin 12 | Tumor necrosis factor-α | Light therapy | Patients | Studies | Tumor necrosis factor-TNF | Index Medicus | Abridged Index Medicus
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6. Full Text Improving survival rates in two models of spontaneous postoperative metastasis in mice by combined administration of a β-adrenergic antagonist and a cyclooxygenase-2 inhibitor
by Glasner, Ariella and Avraham, Roi and Rosenne, Ella and Benish, Marganit and Zmora, Oded and Shemer, Shaily and Meiboom, Hadas and Ben-Eliyahu, Shamgar
The Journal of immunology (1950), ISSN 0022-1767, 03/2010, Volume 184, Issue 5, pp. 2449 - 2457
Life Sciences & Biomedicine | Immunology | Science & Technology | Fas Ligand Protein - metabolism | Postoperative Complications - etiology | Poly I-C - administration & dosage | Postoperative Complications - prevention & control | Male | Postoperative Complications - mortality | Carcinoma, Lewis Lung - surgery | Melanoma, Experimental - surgery | Etodolac - administration & dosage | Neoplasm Metastasis | Propranolol - administration & dosage | Killer Cells, Natural - immunology | Female | Laparotomy - adverse effects | Adrenergic beta-Antagonists - administration & dosage | CD11a Antigen - metabolism | Amputation - adverse effects | Cyclooxygenase 2 Inhibitors - administration & dosage | Mice, Inbred C57BL | Melanoma, Experimental - pathology | Survival Rate | Animals | Interleukin-12 - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Carcinoma, Lewis Lung - pathology | Cell Line, Tumor | Killer Cells, Natural - drug effects | Mice | Killer Cells, Natural - metabolism | Index Medicus | Abridged Index Medicus
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7. Full Text Identification of immune factors regulating antitumor immunity using polymeric vaccines with multiple adjuvants
by Ali, Omar A and Verbeke, Catia and Johnson, Chris and Sands, R. Warren and Lewin, Sarah A and White, Des and Doherty, Edward and Dranoff, Glenn and Mooney, David J
Cancer research (Chicago, Ill.), ISSN 0008-5472, 03/2014, Volume 74, Issue 6, pp. 1670 - 1681
Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Tumors | Neoplasm Transplantation | Oligodeoxyribonucleotides - administration & dosage | Adjuvants, Immunologic - administration & dosage | Poly I-C - administration & dosage | Dendritic Cells - immunology | Lipid A - analogs & derivatives | Drug Carriers - administration & dosage | Mice, 129 Strain | Drug Carriers - chemistry | Adjuvants, Immunologic - pharmacokinetics | Melanoma, Experimental - immunology | Female | Toll-Like Receptors - metabolism | Polyglactin 910 - administration & dosage | T-Lymphocytes, Cytotoxic - immunology | Granulocyte-Macrophage Colony-Stimulating Factor - administration & dosage | Lipid A - administration & dosage | Cancer Vaccines - administration & dosage | Melanoma, Experimental - therapy | Mice, Inbred C57BL | Interleukin-12 - metabolism | Toll-Like Receptors - agonists | Mice, Knockout | Animals | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacokinetics | Cell Line, Tumor | Mice | Delayed-Action Preparations | Index Medicus
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8. Full Text IFN-γ induced by IL-12 administration prevents diabetes by inhibiting pathogenic IL-17 production in NOD mice
by Zhang, Jun and Huang, Zhan and Sun, Rui and Tian, Zhigang and Wei, Haiming
Journal of autoimmunity, ISSN 0896-8411, 2011, Volume 38, Issue 1, pp. 20 - 28
Allergy and Immunology | Interleukin 12 | IFN-γ | Dendritic cells | Type 1 diabetes | Interleukin 17 | Life Sciences & Biomedicine | Immunology | Science & Technology | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Diabetes. Impaired glucose tolerance | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Interleukin-12 Subunit p35 - metabolism | Interleukin-12 Subunit p40 - genetics | Islets of Langerhans - drug effects | Diabetes Mellitus, Type 1 - prevention & control | Gene Expression - drug effects | Diabetes Mellitus, Type 1 - metabolism | Interferon-gamma - metabolism | Dose-Response Relationship, Drug | Interleukin-23 - genetics | Flow Cytometry | Interleukin-23 - metabolism | Islets of Langerhans - metabolism | Dendritic Cells - drug effects | Female | Interferon-gamma - genetics | Interleukin-6 - metabolism | Dendritic Cells - metabolism | Interleukin-12 - pharmacology | Interleukin-12 Subunit p40 - metabolism | Drug Administration Schedule | Enzyme-Linked Immunosorbent Assay | Interleukin-6 - genetics | Mice, Inbred C57BL | Cells, Cultured | Injections, Intraperitoneal | Diabetes Mellitus, Type 1 - genetics | Interleukin-12 Subunit p35 - genetics | Reverse Transcriptase Polymerase Chain Reaction | Interleukin-17 - metabolism | Animals | Interleukin-12 - administration & dosage | Survival Analysis | Mice, Inbred NOD | Mice | Mice, Inbred BALB C | Index Medicus
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9. Full Text Oral Administration of Poly-γ-Glutamate Ameliorates Atopic Dermatitis in Nc/Nga Mice by Suppressing Th2-Biased Immune Response and Production of IL-17A
by Lee, Tae-Young and Kim, Doo-Jin and Won, Ji-Na and Lee, Il-Han and Sung, Moon-Hee and Poo, Haryoung
Journal of investigative dermatology, ISSN 0022-202X, 03/2014, Volume 134, Issue 3, pp. 704 - 711
Life Sciences & Biomedicine | Dermatology | Science & Technology | Dermatitis, Atopic - genetics | Immunoglobulin G - blood | Dendritic Cells - immunology | Dermatologic Agents - administration & dosage | Interleukin-17 - immunology | Male | Polyglutamic Acid - administration & dosage | Th2 Cells - immunology | Th2 Cells - drug effects | Immunoglobulin E - blood | Polyglutamic Acid - analogs & derivatives | Polyglutamic Acid - pharmacology | Mice, Mutant Strains | Dermatitis, Atopic - immunology | Dendritic Cells - drug effects | Dermatologic Agents - pharmacology | Disease Models, Animal | Mast Cells - immunology | Administration, Oral | Mice, Inbred C57BL | Interleukin-12 - metabolism | Mast Cells - drug effects | Interleukin-17 - metabolism | Animals | Dermatitis, Atopic - drug therapy | Interleukin-12 - immunology | Mice | Index Medicus
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10. Full Text Oral Administration of an Active Form of Vitamin D3 (Calcitriol) Decreases Atherosclerosis in Mice by Inducing Regulatory T Cells and Immature Dendritic Cells With Tolerogenic Functions
by Takeda, Masafumi and Yamashita, Tomoya and Sasaki, Naoto and Nakajima, Kenji and Kita, Tomoyuki and Shinohara, Masakazu and Ishida, Tatsuro and Hirata, Ken-ichi
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 12/2010, Volume 30, Issue 12, pp. 2495 - 2503
atherosclerosis | regulatory T cells | immune system | dendritic cells | calcitriol | Fundamental and applied biological sciences. Psychology | Cardiology. Vascular system | Blood vessels and receptors | Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous | Atherosclerosis (general aspects, experimental research) | Biological and medical sciences | Medical sciences | Vertebrates: cardiovascular system | Blood and lymphatic vessels | Spleen - immunology | Apolipoproteins E - deficiency | Interleukin-12 - genetics | Atherosclerosis - genetics | Dendritic Cells - immunology | Spleen - drug effects | RNA, Messenger - metabolism | T-Lymphocytes, Regulatory - immunology | CD11c Antigen - metabolism | Calcitriol - administration & dosage | Forkhead Transcription Factors - metabolism | Inflammation Mediators - metabolism | Aortic Diseases - prevention & control | Anti-Inflammatory Agents - administration & dosage | Dendritic Cells - drug effects | Female | Lymph Nodes - drug effects | Intestine, Small - immunology | Aortic Diseases - pathology | Disease Models, Animal | Immune Tolerance - drug effects | Atherosclerosis - pathology | Atherosclerosis - immunology | Administration, Oral | Aortic Diseases - immunology | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation | B7-1 Antigen - metabolism | Lymph Nodes - immunology | Mice, Knockout | B7-2 Antigen - metabolism | Aortic Diseases - genetics | T-Lymphocytes, Regulatory - drug effects | Animals | Interleukin-2 Receptor alpha Subunit - metabolism | Apolipoproteins E - genetics | Interleukin-10 - genetics | Intestine, Small - drug effects | Immune Tolerance - genetics | Mice | Atherosclerosis - prevention & control | Index Medicus
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