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Journal of Immunology, ISSN 0022-1767, 03/2014, Volume 192, Issue 6, pp. 2722 - 2733
Nasal administration of an oil-in-water nanoemulsion (NE) adjuvant W(80)5EC produces potent systemic and mucosal, Th-1- and Th-17-balanced cellular responses.... 
ADAPTIVE IMMUNITY | SIGNAL-TRANSDUCTION | MONOPHOSPHORYL-LIPID-A | CYTOKINE PRODUCTION | VACCINE ADJUVANT | DELIVERY-SYSTEMS | TOLL-LIKE RECEPTORS | NLRP3 INFLAMMASOME | IMMUNOLOGY | ANTIBODY-RESPONSES | T-CELLS | Adjuvants, Immunologic - administration & dosage | Adjuvants, Immunologic - pharmacology | Oligonucleotide Array Sequence Analysis | Immunity, Humoral - immunology | Interleukin-12 - genetics | Dendritic Cells - immunology | Humans | NF-kappa B - immunology | NF-kappa B - metabolism | Transcriptome - immunology | Emulsions - pharmacology | Signal Transduction - immunology | Immunity, Cellular - drug effects | Emulsions - administration & dosage | HEK293 Cells | Interleukin-12 Receptor beta 1 Subunit - genetics | Myeloid Differentiation Factor 88 - immunology | Dendritic Cells - drug effects | Female | Toll-Like Receptors - metabolism | Interleukin-12 Receptor beta 1 Subunit - metabolism | Dendritic Cells - metabolism | Cell Line | Immunity, Cellular - genetics | Immunity, Humoral - genetics | Mice, Inbred C57BL | Toll-Like Receptors - immunology | Cells, Cultured | Myeloid Differentiation Factor 88 - genetics | Interleukin-12 - metabolism | Signal Transduction - genetics | Transcriptome - drug effects | Transcriptome - genetics | Reverse Transcriptase Polymerase Chain Reaction | Administration, Intranasal | Mice, Knockout | Immunity, Cellular - immunology | Animals | Signal Transduction - drug effects | Toll-Like Receptors - genetics | Interleukin-12 - immunology | Immunity, Humoral - drug effects | Mice | Interleukin-12 Receptor beta 1 Subunit - immunology | Myeloid Differentiation Factor 88 - metabolism | Index Medicus | Abridged Index Medicus | Immunotherapy and Vaccines
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 01/2010, Volume 362, Issue 2, pp. 118 - 128
In this 12-week randomized trial comparing two biologic agents known to be effective for psoriasis, ustekinumab (an interleukin-12 and interleukin-23 blocker)... 
RANDOMIZED-CONTROLLED-TRIAL | MEDICINE, GENERAL & INTERNAL | PLACEBO | CHRONIC PLAQUE PSORIASIS | EFFICACY | SAFETY | DOUBLE-BLIND | METHOTREXATE | TNF INHIBITION | INDUCTION | INTERLEUKIN-12/23 MONOCLONAL-ANTIBODY | Severity of Illness Index | Psoriasis - drug therapy | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Immunologic Factors - administration & dosage | Immunoglobulin G - therapeutic use | Ustekinumab | Antibodies, Monoclonal - therapeutic use | Male | Receptors, Tumor Necrosis Factor - administration & dosage | Immunoglobulin G - administration & dosage | Receptors, Tumor Necrosis Factor - therapeutic use | Antibodies, Monoclonal, Humanized | Etanercept | Antibodies, Monoclonal - administration & dosage | Interleukin-23 - antagonists & inhibitors | Interleukin-12 - antagonists & inhibitors | Adult | Female | Immunosuppressive Agents - administration & dosage | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Immunologic Factors - therapeutic use | Dosage and administration | Psoriasis | Comparative analysis | Drug therapy | Fees & charges | Cytokines | Stock options | Laboratories | Research & development--R&D | Equity | Interleukin 23 | Interleukin 12 | Tumor necrosis factor-α | Light therapy | Patients | Studies | Tumor necrosis factor-TNF | Index Medicus | Abridged Index Medicus
Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 9/2013, Volume 208, Issue 5, pp. 818 - 829
Journal Article
Cancer Research, ISSN 0008-5472, 03/2014, Volume 74, Issue 6, pp. 1670 - 1681
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 2011, Volume 38, Issue 1, pp. 20 - 28
Abstract Interleukin 12 (IL-12) is a pivotal Th1-associated cytokine and a potent immunoregulatory molecule. However, the role of IL-12 in inducing immune... 
Allergy and Immunology | Interleukin 12 | IFN-γ | Dendritic cells | Type 1 diabetes | Interleukin 17 | IMMUNITY | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | CD4 T-CELLS | INTERLEUKIN-12 | IMMUNOLOGY | TH1 RESPONSE | IFN-gamma | INFLAMMATION | IN-VIVO | ANTIGEN-PRESENTING CELLS | TRANSGENIC MICE | Interleukin-12 Subunit p35 - metabolism | Interleukin-12 Subunit p40 - genetics | Islets of Langerhans - drug effects | Diabetes Mellitus, Type 1 - prevention & control | Gene Expression - drug effects | Diabetes Mellitus, Type 1 - metabolism | Interferon-gamma - metabolism | Dose-Response Relationship, Drug | Interleukin-23 - genetics | Flow Cytometry | Interleukin-23 - metabolism | Islets of Langerhans - metabolism | Dendritic Cells - drug effects | Female | Interferon-gamma - genetics | Interleukin-6 - metabolism | Dendritic Cells - metabolism | Interleukin-12 - pharmacology | Interleukin-12 Subunit p40 - metabolism | Drug Administration Schedule | Enzyme-Linked Immunosorbent Assay | Interleukin-6 - genetics | Mice, Inbred C57BL | Cells, Cultured | Injections, Intraperitoneal | Diabetes Mellitus, Type 1 - genetics | Interleukin-12 Subunit p35 - genetics | Reverse Transcriptase Polymerase Chain Reaction | Interleukin-17 - metabolism | Animals | Interleukin-12 - administration & dosage | Survival Analysis | Mice, Inbred NOD | Mice | Mice, Inbred BALB C | Index Medicus
Journal Article
Journal of Immunology, ISSN 0022-1767, 02/1998, Volume 160, Issue 4, pp. 1742 - 1749
We evaluated the mechanism of the antitumor effects of mouse rIFN-gamma-inducing factor/IL-18 protein on the growth of mouse tumor cell lines in vivo. Mice... 
INTERFERON-GAMMA | ANGIOGENESIS IN-VIVO | METASTASES | INTERLEUKIN-12 | ALPHA | CYTOKINE | MICE | IMMUNOLOGY | TYPE-1 | TUMORS | T-CELLS | Neoplasm Transplantation | CD8-Positive T-Lymphocytes - pathology | Interleukin-12 - genetics | Interferon Inducers - antagonists & inhibitors | Interleukin-12 - physiology | Interleukin-10 - blood | Fibrosarcoma - immunology | Antineoplastic Agents - administration & dosage | Lymphocyte Depletion | Sarcoma, Experimental - immunology | Melanoma, Experimental - prevention & control | G(M1) Ganglioside - immunology | Melanoma, Experimental - immunology | Gene Deletion | Killer Cells, Natural - immunology | Interferon-gamma - genetics | Tumor Cells, Cultured | Interleukin-18 | Immune Sera - pharmacology | Sarcoma, Experimental - prevention & control | Adjuvants, Immunologic - physiology | Antineoplastic Agents - antagonists & inhibitors | Mice, Inbred C57BL | Injections, Intraperitoneal | Interferon-gamma - physiology | Melanoma, Experimental - pathology | Cytokines - administration & dosage | Mice, Knockout | Animals | Growth Inhibitors - administration & dosage | Interleukin-12 - administration & dosage | CD8-Positive T-Lymphocytes - drug effects | Mice | CD4-CD8 Ratio - drug effects | Cytokines - antagonists & inhibitors | Interferon Inducers - administration & dosage | Growth Inhibitors - antagonists & inhibitors | Interferon-gamma - blood | Cytotoxicity, Immunologic | Fibrosarcoma - prevention & control | Index Medicus | Abridged Index Medicus | AIDS/HIV
Journal Article
Journal of Immunology, ISSN 0022-1767, 03/2010, Volume 184, Issue 5, pp. 2449 - 2457
Journal Article
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 12/2017, Volume 494, Issue 1-2, pp. 379 - 383
Z is a micro-algae that is used as a food or nutritional supplement. Paramylon, the carbohydrate storage substance of Z has β-1, 3-glucan structure. Z and... 
Euglena gracilis Z | Influenza virus | Interferon-γ | Paramylon | β-1, 3-D-glucan | Interleukin-12 | Interferon-gamma | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | INJURY | ALPHA | MODEL | IL-12 | beta-1, 3-D-glucan | PATHOGENESIS | BIOPHYSICS | INFLAMMATION | Adjuvants, Immunologic - administration & dosage | Influenza A Virus, H1N1 Subtype - growth & development | Glucans - administration & dosage | Lung - virology | Female | Interleukin-1beta - biosynthesis | Euglena gracilis - chemistry | Interleukin-12 - biosynthesis | Administration, Oral | Euglena gracilis - immunology | Interleukin-1beta - immunology | Influenza A Virus, H1N1 Subtype - pathogenicity | Orthomyxoviridae Infections - diet therapy | Influenza A Virus, H1N1 Subtype - drug effects | Animals | Orthomyxoviridae Infections - mortality | Interferon-gamma - immunology | Lung - drug effects | Interleukin-12 - immunology | Interleukin-6 - immunology | Survival Analysis | Interleukin-6 - biosynthesis | Interleukin-10 - biosynthesis | Mice | Mice, Inbred BALB C | Dietary Supplements | Interleukin-10 - immunology | Orthomyxoviridae Infections - virology | Interferon-gamma - biosynthesis | Lung - immunology | Orthomyxoviridae Infections - immunology | Influenza viruses | Interleukins | Influenza | Dietary supplements | Interferon | Biological response modifiers | Health aspects | Index Medicus
Journal Article
Journal of Medical Virology, ISSN 0146-6615, 09/2016, Volume 88, Issue 9, pp. 1487 - 1496
Journal Article
Molecular Therapy, ISSN 1525-0016, 09/2012, Volume 20, Issue 9, pp. 1664 - 1675
Journal Article
Journal Article