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Journal of Immunology, ISSN 0022-1767, 05/2013, Volume 190, Issue 9, pp. 4640 - 4649
Dendritic cells (DC) are professional APCs that regulate innate and adaptive immunity. The role of fatty-acid synthesis in DC development and function is... 
CANCER-CELLS | APOPTOSIS | KAPPA-B ACTIVATION | UNFOLDED PROTEIN RESPONSE | CYTOKINE PRODUCTION | SYNTHASE INHIBITION | ER STRESS | MAP KINASE | MACROPHAGES | ENDOPLASMIC-RETICULUM STRESS | IMMUNOLOGY | Fatty Acids - immunology | Leukocytes, Mononuclear - metabolism | Chemokine CCL2 - immunology | Dendritic Cells - immunology | Humans | Caspase 3 - metabolism | Male | Cyclin B1 - metabolism | Interferon-gamma - metabolism | PPAR gamma - metabolism | CD4-Positive T-Lymphocytes - immunology | Mitogen-Activated Protein Kinase Kinases - metabolism | Liver - immunology | CD8-Positive T-Lymphocytes - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Liver - metabolism | CD4-Positive T-Lymphocytes - metabolism | Interleukin-12 - metabolism | B7-2 Antigen - metabolism | Cell Differentiation - immunology | Intercellular Adhesion Molecule-1 - metabolism | Proto-Oncogene Proteins c-akt - immunology | T-Lymphocytes, Cytotoxic - metabolism | Endoplasmic Reticulum - immunology | Interleukin-12 - immunology | Mice | Killer Cells, Natural - metabolism | CD8-Positive T-Lymphocytes - immunology | bcl-X Protein - metabolism | Fatty Acids - biosynthesis | Mitogen-Activated Protein Kinase Kinases - immunology | Caspase 3 - immunology | Endoplasmic Reticulum - metabolism | Genes, MHC Class II - immunology | PPAR gamma - immunology | Cyclin B1 - immunology | Leukocytes, Mononuclear - immunology | bcl-X Protein - immunology | Killer Cells, Natural - immunology | Chemokine CCL2 - metabolism | B7-2 Antigen - immunology | Fatty Acids - metabolism | Dendritic Cells - metabolism | T-Lymphocytes, Cytotoxic - immunology | B7-1 Antigen - immunology | Intercellular Adhesion Molecule-1 - immunology | Mice, Inbred C57BL | B7-1 Antigen - metabolism | Animals | Apoptosis - immunology | Interferon-gamma - immunology | Dendritic Cells - cytology | Index Medicus | Abridged Index Medicus | Fatty-acid synthesis | ER stress | NK cells | T cells | Bone marrow dendritic cells
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2006, Volume 116, Issue 4, pp. 916 - 928
Journal Article
Nature Immunology, ISSN 1529-2908, 08/2005, Volume 6, Issue 8, pp. 777 - 784
Journal Article
Blood, ISSN 0006-4971, 12/2012, Volume 120, Issue 24, pp. 4751 - 4760
Natural killer (NK) cells are lymphocytes that play an important role in the immune response to infection and malignancy. Recent studies in mice have shown... 
INNATE | NATURAL-KILLER-CELLS | INFECTION | HEMATOLOGY | EXPANSION | Receptors, Interleukin-12 - immunology | Antigens, CD - immunology | Interleukin-18 - immunology | Humans | Lectins, C-Type - immunology | Interferon-gamma - metabolism | Interleukin-15 - immunology | Antigens, CD - metabolism | NK Cell Lectin-Like Receptor Subfamily D - immunology | Lectins, C-Type - metabolism | NK Cell Lectin-Like Receptor Subfamily C - immunology | Lymphocyte Activation - immunology | Flow Cytometry | Time Factors | Killer Cells, Natural - immunology | Receptors, Interleukin-12 - genetics | Interferon-gamma - genetics | CD56 Antigen - immunology | Immunologic Memory - immunology | Cytokines - immunology | Interleukin-12 - pharmacology | Receptors, Interleukin-18 - metabolism | CD56 Antigen - metabolism | NK Cell Lectin-Like Receptor Subfamily C - metabolism | Antigens, Differentiation, T-Lymphocyte - immunology | Antigens, Differentiation, T-Lymphocyte - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Interleukin-15 - pharmacology | Receptors, Interleukin-12 - metabolism | Lymphocyte Activation - drug effects | Interferon-gamma - immunology | Interleukin-12 - immunology | K562 Cells | Receptors, Interleukin-18 - genetics | Receptors, Interleukin-18 - immunology | Cell Proliferation - drug effects | Interleukin-18 - pharmacology | Killer Cells, Natural - drug effects | Killer Cells, Natural - metabolism | NK Cell Lectin-Like Receptor Subfamily D - metabolism | Cytokines - pharmacology | Index Medicus | Abridged Index Medicus | Immunobiology
Journal Article
Journal Article
Developmental and Comparative Immunology, ISSN 0145-305X, 03/2015, Volume 49, Issue 1, pp. 38 - 43
Dendritic cells (DCs) are among the most important professional antigen-presenting cells (APCs) that participate in various biological activities in mammals.... 
Zebrafish dendritic cells | Antigen presentation | Co-stimulatory signals | Surface phenotypic molecules | ZEBRAFISH | SUBSETS | INNATE | IMMUNOLOGY | IDENTIFICATION | MATURATION | ADAPTIVE IMMUNITY | ORIGIN | FISHERIES | ZOOLOGY | ANTIGEN-PRESENTATION | SUPERFAMILY | LINEAGE | Interleukin-12 Subunit p40 - genetics | Receptor, Macrophage Colony-Stimulating Factor - immunology | B7-1 Antigen - genetics | Zebrafish - immunology | Membrane Glycoproteins - metabolism | Dendritic Cells - immunology | Male | Immunoglobulins - genetics | Antigens, CD - genetics | Antigens, CD - metabolism | Immunoglobulins - metabolism | Lectins, C-Type - metabolism | Lymphocyte Activation - immunology | Gene Expression - immunology | Zebrafish Proteins - immunology | Receptors, Antigen, T-Cell - immunology | Cell Membrane - metabolism | Interleukin-12 Subunit p40 - immunology | GATA2 Transcription Factor - genetics | Interleukin-12 Subunit p40 - metabolism | Antigen-Presenting Cells - metabolism | Receptors, Antigen, T-Cell - metabolism | Receptor, Macrophage Colony-Stimulating Factor - genetics | Reverse Transcriptase Polymerase Chain Reaction | Cell Adhesion Molecules - metabolism | Receptors, Cell Surface - immunology | Zebrafish - genetics | Microscopy, Confocal | Histocompatibility Antigens Class II - immunology | Cell Membrane - immunology | Receptors, Antigen, T-Cell - genetics | Zebrafish Proteins - genetics | Receptors, Cell Surface - genetics | Antigens, CD - immunology | Cell Adhesion Molecules - genetics | Immunoglobulins - immunology | Lectins, C-Type - immunology | Cell Adhesion Molecules - immunology | Lectins, C-Type - genetics | Receptor, Macrophage Colony-Stimulating Factor - metabolism | Flow Cytometry | Female | Histocompatibility Antigens Class II - metabolism | Membrane Glycoproteins - immunology | Dendritic Cells - metabolism | B7-1 Antigen - immunology | Zebrafish Proteins - metabolism | Receptors, Cell Surface - metabolism | GATA2 Transcription Factor - immunology | Immunophenotyping | B7-1 Antigen - metabolism | Antigen-Presenting Cells - immunology | Membrane Glycoproteins - genetics | Animals | Zebrafish - metabolism | GATA2 Transcription Factor - metabolism | Histocompatibility Antigens Class II - genetics | Dendritic cells | Chemical properties | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 10/2012, Volume 490, Issue 7421, pp. 502 - 507
The AP1 transcription factor Batf3 is required for homeostatic development of CD8 alpha(+) classical dendritic cells that prime CD8 T-cell responses against... 
INTERFERON-REGULATORY FACTOR-4 | MULTIDISCIPLINARY SCIENCES | IN-VIVO | TRANSCRIPTION | CLASS-SWITCH RECOMBINATION | CD8-ALPHA(+) | INFECTION | EXPRESSION | T-CELLS | NEGATIVE REGULATOR | B-ATF | Toxoplasma - immunology | Neoplasm Transplantation | Basic-Leucine Zipper Transcription Factors - metabolism | Dendritic Cells - immunology | Leucine Zippers | Interferon Regulatory Factors - metabolism | Fibrosarcoma - immunology | Male | Fibrosarcoma - metabolism | Interferon Regulatory Factors - deficiency | Antigens, CD - metabolism | CD4-Positive T-Lymphocytes - immunology | Fibrosarcoma - pathology | Antigen Presentation | Repressor Proteins - deficiency | Basic-Leucine Zipper Transcription Factors - deficiency | T-Lymphocytes, Helper-Inducer - immunology | T-Lymphocytes, Helper-Inducer - cytology | Interleukin-10 - metabolism | Female | Cell Differentiation | Dendritic Cells - metabolism | Protein Structure, Tertiary | T-Lymphocytes, Helper-Inducer - metabolism | CD4-Positive T-Lymphocytes - cytology | Mice, Inbred C57BL | Gene Expression Regulation | CTLA-4 Antigen - metabolism | Interferon Regulatory Factors - genetics | Repressor Proteins - genetics | Integrin alpha Chains - metabolism | Interleukin-12 - metabolism | Basic-Leucine Zipper Transcription Factors - genetics | CD8 Antigens - immunology | Cell Lineage | CD8 Antigens - metabolism | Animals | Basic-Leucine Zipper Transcription Factors - chemistry | Interleukin-12 - immunology | Cell Line, Tumor | Protein Binding | Dendritic Cells - cytology | Mice | Oncogene Protein p65(gag-jun) - metabolism | Physiological aspects | Transcription factors | Research | Cell development (Biology) | Dendritic cells | T cells | Proteins | Medical research | Immunology | Rodents | Immune system | Index Medicus
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 04/2010, Volume 207, Issue 4, pp. 721 - 730
Plasmacytoid dendritic cells (pDCs) play a key role in antiviral immunity, but also contribute to the pathogenesis of certain autoimmune diseases, by producing... 
MEDICINE, RESEARCH & EXPERIMENTAL | CPG MOTIFS | LYMPHOCYTE MIGRATION | PROTEIN DOCK2 | RECOGNITION | PREDENDRITIC CELLS | NEUTROPHIL CHEMOTAXIS | KAPPA-B | IMMUNOLOGY | INTERFERON-ALPHA PRODUCTION | BACTERIAL-DNA | MOTILITY | Interferon-alpha - pharmacology | Interleukin-1 Receptor-Associated Kinases - metabolism | Dendritic Cells - immunology | Actins - metabolism | rac GTP-Binding Proteins - metabolism | Interleukin-12 Subunit p40 - blood | Male | GTPase-Activating Proteins - metabolism | Endosomes - metabolism | Toll-Like Receptor 9 - agonists | Interferon Type I - biosynthesis | Signal Transduction - immunology | STAT1 Transcription Factor - metabolism | I-kappa B Kinase - metabolism | rac GTP-Binding Proteins - genetics | Interferon Type I - metabolism | Dendritic Cells - drug effects | Female | Influenza A virus - immunology | Neuropeptides - genetics | Phosphorylation - drug effects | Oligodeoxyribonucleotides - metabolism | Dendritic Cells - metabolism | Toll-Like Receptor 7 - agonists | Interferon-alpha - metabolism | Interleukin-12 Subunit p40 - metabolism | Mice, Inbred C57BL | Toll-Like Receptors - immunology | Membrane Glycoproteins - agonists | Neuropeptides - metabolism | Imidazoles - pharmacology | Interferon Regulatory Factor-7 - metabolism | Toll-Like Receptors - agonists | Mice, Knockout | Animals | Herpesvirus 2, Human - immunology | Interferon-beta - metabolism | Signal Transduction - drug effects | Interferon-alpha - blood | Mice | rac1 GTP-Binding Protein | Oligodeoxyribonucleotides - pharmacology | Toll-Like Receptor 9 - metabolism | Mitogen-Activated Protein Kinases - metabolism | Index Medicus | Brief Definitive Report
Journal Article
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 04/2017, Volume 486, Issue 2, pp. 451 - 457
Klotho, an antiaging protein, can extend the lifespan and modulate cellular responses to inflammation and oxidative stress which can ameliorate chronic kidney... 
Cyclosporine A | PDLIM2 | Nephropathy | Klotho | NF-kB p65 | GLOMERULONEPHRITIS | OXIDATIVE STRESS | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MODEL | BIOPHYSICS | DISEASE | MICE | KIDNEY | ANTIAGING GENE | RENAL INJURY | EXPRESSION | Tumor Necrosis Factor-alpha - metabolism | RNA, Small Interfering - genetics | Epithelial Cells - metabolism | Interleukin-12 - genetics | Blood Urea Nitrogen | Epithelial Cells - drug effects | Tumor Necrosis Factor-alpha - genetics | Glucuronidase - metabolism | Male | Cyclosporine | LIM Domain Proteins - metabolism | Transcription Factor RelA - genetics | Nephritis, Interstitial - metabolism | Nephritis, Interstitial - pathology | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Adenoviridae - genetics | Chemokine CCL2 - metabolism | Interleukin-6 - metabolism | Nephritis, Interstitial - chemically induced | Cell Line | Kidney Tubules, Proximal - pathology | Genetic Vectors - chemistry | Interleukin-6 - genetics | Macrophages - pathology | Signal Transduction | LIM Domain Proteins - antagonists & inhibitors | Gene Expression Regulation | Genetic Vectors - metabolism | Chemokine CCL2 - genetics | Epithelial Cells - pathology | Interleukin-12 - metabolism | Mice, Inbred ICR | Macrophages - metabolism | Animals | Glucuronidase - genetics | Nephritis, Interstitial - genetics | Nitric Oxide Synthase Type II - genetics | Transcription Factor RelA - metabolism | Adaptor Proteins, Signal Transducing - genetics | Kidney Tubules, Proximal - metabolism | Creatinine - blood | LIM Domain Proteins - genetics | Mice | Adenoviridae - metabolism | Glucuronidase - pharmacology | Adaptor Proteins, Signal Transducing - metabolism | Nitric Oxide Synthase Type II - metabolism | RNA, Small Interfering - metabolism | Medical research | Urea | Medical colleges | Chronic kidney failure | RNA | Luciferase | Medicine, Experimental | Index Medicus
Journal Article
Scandinavian Journal of Immunology, ISSN 0300-9475, 09/2014, Volume 80, Issue 3, pp. 180 - 190
Experimental autoimmune neuritis ( EAN ), an animal model of human Guillain–Barré syndrome, has long been considered as a T helper (Th) 1 cell–mediated... 
PHASE | INTERLEUKIN-17 | ROLES | GUILLAIN-BARRE-SYNDROME | IL-17 | REGULATORY T-CELLS | TNF-ALPHA | IMMUNOLOGY | LEWIS RATS | DEFICIENCY | BETA | Forkhead Transcription Factors - immunology | T-Lymphocytes, Regulatory - metabolism | Spleen - immunology | Humans | Receptors, Interleukin-17 - immunology | Interleukin-17 - immunology | Male | Th2 Cells - immunology | Interferon-gamma - metabolism | Th1 Cells - immunology | Cauda Equina - metabolism | Interleukins - metabolism | T-Lymphocytes, Regulatory - immunology | Th1 Cells - metabolism | Flow Cytometry | Th17 Cells - metabolism | Time Factors | Forkhead Transcription Factors - metabolism | Interleukins - immunology | Interleukin-10 - metabolism | Neuritis, Autoimmune, Experimental - immunology | Receptors, Interleukin-17 - metabolism | Interleukin-6 - metabolism | Cytokines - immunology | Disease Models, Animal | Guillain-Barre Syndrome - metabolism | Interleukin-17 - blood | Severity of Illness Index | Cytokines - metabolism | Interleukins - blood | Mice, Inbred C57BL | Cauda Equina - immunology | Interleukin-12 - metabolism | Th2 Cells - metabolism | Interleukin-17 - metabolism | Animals | Guillain-Barre Syndrome - immunology | Spleen - metabolism | Interferon-gamma - immunology | Neuritis, Autoimmune, Experimental - metabolism | Interleukin-12 - immunology | Interleukin-6 - immunology | Th17 Cells - immunology | Guillain-Barre Syndrome - pathology | Interleukin-10 - immunology | Neuritis, Autoimmune, Experimental - pathology | Cytokines | Inflammation | Nerves | Index Medicus
Journal Article