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The Journal of Immunology, ISSN 0022-1767, 07/2009, Volume 183, Issue 1, pp. 137 - 144
Journal Article
Immunology and Cell Biology, ISSN 0818-9641, 10/2007, Volume 85, Issue 7, pp. 558 - 566
It has been recognized that protease‐activated receptors (PARs), interleukin (IL)‐4 and IL‐6 are involved in the pathogenesis of allergic diseases, and that... 
mast cell | IL‐4 | IL‐12 | trypsin | protease‐activated receptor | tryptase | IL-4 | Trypsin | Mast cell | Protease-activated receptor | IL-12 | Tryptase | SERINE PROTEINASES | THROMBIN RECEPTORS | HISTAMINE-RELEASE | INDUCTION | IMMUNOLOGY | HUMAN AIRWAYS | CELL BIOLOGY | SMOOTH-MUSCLE | INTERFERON-GAMMA | IN-VIVO | protease-activated receptor | VASCULAR ENDOTHELIAL-CELLS | INFLAMMATORY MEDIATORS | Receptors, Proteinase-Activated - metabolism | Nitriles - pharmacology | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Extracellular Signal-Regulated MAP Kinases - metabolism | RNA, Messenger - metabolism | Receptors, Proteinase-Activated - genetics | Trypsin - pharmacology | Mast Cells - metabolism | Flavonoids - pharmacology | Chromones - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Interleukin-12 - pharmacology | Butadienes - pharmacology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Imidazoles - pharmacology | Tyrphostins - pharmacology | Mast Cells - drug effects | Gene Expression Regulation - drug effects | Interleukin-4 - secretion | Animals | Tryptases - pharmacology | Mice | Pyridines - pharmacology | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Tyrphostins, pharmacology | Up-Regulation | Chromones, pharmacology | Trypsin, pharmacology | Humans | Imidazoles, pharmacology | Tryptases, pharmacology | Oligopeptides, pharmacology | Interleukin-12, pharmacology | Flow Cytometry | Pyridines, pharmacology | Polymerase Chain Reaction | Receptor, PAR-1, drug effects | Morpholines, pharmacology | RNA, Messenger, metabolism | Flavonoids, pharmacology | Receptor, PAR-2, drug effects | Receptors, Thrombin, drug effects | Enzyme-Linked Immunosorbent Assay | Signal Transduction | Butadienes, pharmacology | Down-Regulation | Mast Cells, drug effects | Interleukin-6, secretion | Nitriles, pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Interleukin-4, secretion | Fluorescent Antibody Technique
Journal Article
The Journal of Immunology, ISSN 0022-1767, 04/2003, Volume 170, Issue 8, pp. 4069 - 4076
It is widely believed that generation of mature dendritic cells (DCs) with full T cell stimulatory capacity from human monocytes in vitro requires 5-7 days of... 
IL-12 PRODUCTION | IN-VITRO | ACTIVATION | RECEPTOR EXPRESSION | ALPHA COOPERATE | SUBSETS | CD40 LIGAND | INTERLEUKIN-12 | IMMUNOLOGY | MATURATION | PROSTAGLANDIN-E2 | Stem Cells - immunology | Dendritic Cells - immunology | Humans | Interphase - immunology | Monocytes - immunology | Cell Culture Techniques - methods | Interleukin-4 - pharmacology | Lymphocyte Activation - immunology | Dextrans - immunology | Time Factors | Inflammation Mediators - pharmacology | Chemokines, CXC - pharmacology | Endocytosis - immunology | Interleukin-12 - biosynthesis | Dextrans - metabolism | Dinoprostone - pharmacology | Chemokines, CC - pharmacology | Solubility | Interleukin-12 - metabolism | Second Messenger Systems - immunology | Interleukin-1 - pharmacology | Receptors, CXCR4 - metabolism | Cell Differentiation - immunology | Tumor Necrosis Factor-alpha - pharmacology | CD40 Ligand - pharmacology | Ligands | Tetanus Toxoid - immunology | T-Lymphocyte Subsets - immunology | Monocytes - cytology | Interleukin-12 - physiology | Chemokine CCL21 | Monocytes - metabolism | Stem Cells - cytology | Stem Cells - metabolism | Epitopes, T-Lymphocyte - immunology | Dendritic Cells - metabolism | Chemokine CXCL12 | Receptors, CCR7 | Receptors, Chemokine - metabolism | Stromal Cells - metabolism | Cells, Cultured | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology | Immunophenotyping | Stromal Cells - immunology | Chemokines, CXC - metabolism | Dendritic Cells - cytology | Drug Combinations | Interferon-gamma - biosynthesis | Chemokines, CC - metabolism
Journal Article
Journal Article
European Journal of Immunology, ISSN 0014-2980, 06/2007, Volume 37, Issue 6, pp. 1600 - 1612
Zymosan is a particulate yeast preparation that elicits high levels of IL‐2 and IL‐10 from dendritic cells (DC) and engages multiple innate receptors,... 
Zymosan | Dendritic cells | Syk | C‐type lectins | Pattern recognition receptors | C-type lectins | C-FOS | PROTEIN-KINASE | TOLL-LIKE RECEPTOR | LIPOPOLYSACCHARIDE ACTIVATION | INNATE IMMUNE-SYSTEM | IMMUNOLOGY | pattern recognition receptors | BETA-GLUCAN RECEPTOR | SIGNAL-TRANSDUCTION | TUMOR-NECROSIS-FACTOR | dendritic cells | zymosan | MESSENGER-RNA DECAY | Cysteine - analogs & derivatives | Interleukin-12 Subunit p40 - genetics | Gene Expression - drug effects | Nitriles - pharmacology | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Extracellular Signal-Regulated MAP Kinases - metabolism | Zymosan - pharmacology | Protein-Tyrosine Kinases - physiology | Signal Transduction - immunology | Protein-Tyrosine Kinases - genetics | Cysteine - pharmacology | Interleukin-10 - metabolism | Dendritic Cells - drug effects | Flavonoids - pharmacology | Phosphorylation - drug effects | Intracellular Signaling Peptides and Proteins - genetics | Syk Kinase | Dendritic Cells - metabolism | Interleukin-2 - metabolism | Cell Line | Butadienes - pharmacology | Membrane Proteins - genetics | Lectins, C-Type | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Myeloid Differentiation Factor 88 - genetics | Glucans - pharmacology | Nerve Tissue Proteins - genetics | Mice, Knockout | Interleukin-2 - genetics | Animals | Signal Transduction - drug effects | Lipoproteins - pharmacology | Interleukin-10 - genetics | Mice | Enzyme Activation | Intracellular Signaling Peptides and Proteins - physiology | Oligopeptides - pharmacology | Peptidoglycan - pharmacology | Lipopeptides
Journal Article
Blood, ISSN 0006-4971, 12/2012, Volume 120, Issue 24, pp. 4751 - 4760
Natural killer (NK) cells are lymphocytes that play an important role in the immune response to infection and malignancy. Recent studies in mice have shown... 
INNATE | NATURAL-KILLER-CELLS | INFECTION | HEMATOLOGY | EXPANSION | Receptors, Interleukin-12 - immunology | Antigens, CD - immunology | Interleukin-18 - immunology | Humans | Lectins, C-Type - immunology | Interferon-gamma - metabolism | Interleukin-15 - immunology | Antigens, CD - metabolism | NK Cell Lectin-Like Receptor Subfamily D - immunology | Lectins, C-Type - metabolism | NK Cell Lectin-Like Receptor Subfamily C - immunology | Lymphocyte Activation - immunology | Flow Cytometry | Time Factors | Killer Cells, Natural - immunology | Receptors, Interleukin-12 - genetics | Interferon-gamma - genetics | CD56 Antigen - immunology | Immunologic Memory - immunology | Cytokines - immunology | Interleukin-12 - pharmacology | Receptors, Interleukin-18 - metabolism | CD56 Antigen - metabolism | NK Cell Lectin-Like Receptor Subfamily C - metabolism | Antigens, Differentiation, T-Lymphocyte - immunology | Antigens, Differentiation, T-Lymphocyte - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Interleukin-15 - pharmacology | Receptors, Interleukin-12 - metabolism | Lymphocyte Activation - drug effects | Interferon-gamma - immunology | Interleukin-12 - immunology | K562 Cells | Receptors, Interleukin-18 - genetics | Receptors, Interleukin-18 - immunology | Cell Proliferation - drug effects | Interleukin-18 - pharmacology | Killer Cells, Natural - drug effects | Killer Cells, Natural - metabolism | NK Cell Lectin-Like Receptor Subfamily D - metabolism | Cytokines - pharmacology | Immunobiology
Journal Article
Infection and Immunity, ISSN 0019-9567, 12/2005, Volume 73, Issue 12, pp. 7967 - 7976
Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
INFECTIOUS DISEASES | HUMAN MONOCYTIC CELLS | LIPOTEICHOIC ACID | MURAMYL DIPEPTIDE | HOST RECOGNITION | WALL COMPONENTS | IFN-GAMMA | ADJUVANT ACTIVITY | DIAMINOPIMELIC ACID | IMMUNOLOGY | BACTERIAL PEPTIDOGLYCAN | CUTTING EDGE | Adjuvants, Immunologic - pharmacology | Diaminopimelic Acid - pharmacology | Dendritic Cells - immunology | Humans | RNA, Messenger - analysis | Intracellular Signaling Peptides and Proteins - metabolism | RNA, Messenger - metabolism | Th1 Cells - immunology | Th1 Cells - metabolism | Dendritic Cells - drug effects | Toll-Like Receptors - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Polylysine - pharmacology | Poly I-C - pharmacology | Cytokines - metabolism | Interleukin-12 - metabolism | Nod2 Signaling Adaptor Protein | Adaptor Proteins, Signal Transducing - agonists | Toll-Like Receptors - agonists | Acetylmuramyl-Alanyl-Isoglutamine - pharmacology | Drug Synergism | Diaminopimelic Acid - analogs & derivatives | Intracellular Signaling Peptides and Proteins - agonists | Toll-Like Receptors - genetics | Adaptor Proteins, Signal Transducing - genetics | Lipid A - pharmacology | Nod1 Signaling Adaptor Protein | Adaptor Proteins, Signal Transducing - metabolism | Oligodeoxyribonucleotides - pharmacology | Oligopeptides - pharmacology | Host Response and Inflammation
Journal Article
Blood, ISSN 0006-4971, 2010, Volume 116, Issue 4, pp. 564 - 574
Currently dendritic cell (DC)-based vaccines are explored in clinical trials, predominantly in cancer patients. Murine studies showed that only maturation with... 
MIGRATION | BACILLUS-CALMETTE-GUERIN | CYTOKINE PRODUCTION | IMMUNE-RESPONSES | RECEPTOR | INTERLEUKIN-12 | MELANOMA PATIENTS | MATURATION | IL-12 | HEMATOLOGY | T-CELLS | Dendritic Cells - immunology | Humans | Vaccines, Synthetic - pharmacology | Dendritic Cells - physiology | Monocytes - metabolism | BCG Vaccine - pharmacology | Monocytes - immunology | Diphtheria-Tetanus-acellular Pertussis Vaccines - pharmacology | Vaccines - pharmacology | Lymphocyte Activation - immunology | Vaccines, Synthetic - metabolism | Typhoid-Paratyphoid Vaccines - pharmacology | Dendritic Cells - drug effects | Toll-Like Receptors - metabolism | Drug Evaluation, Preclinical | Monocytes - physiology | Dendritic Cells - metabolism | Diphtheria-Tetanus-acellular Pertussis Vaccines - immunology | Polysaccharides, Bacterial - pharmacology | Dinoprostone - pharmacology | Toll-Like Receptors - immunology | Cells, Cultured | Polysaccharides, Bacterial - immunology | Vaccines - immunology | Interleukin-12 - metabolism | Monocytes - drug effects | Cell Differentiation - immunology | Cell Movement - drug effects | Influenza Vaccines - pharmacology | Influenza Vaccines - immunology | Cell Differentiation - drug effects | Lymphocyte Activation - drug effects | Preventive Medicine | BCG Vaccine - immunology | Ligands | Typhoid-Paratyphoid Vaccines - immunology
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2002, Volume 99, Issue 5, pp. 2995 - 3000
Suberoylanilide hydroxamic acid (SAHA) is a hydroxamic acid-containing hybrid polar molecule; SAHA specifically binds to and inhibits the activity of histone... 
Biological Sciences | Messenger RNA | Antiinflammatories | Cytokines | Butyrates | Secretion | Cell lines | Histones | Mice | Macrophages | Tumors | CELLS | APOPTOSIS | ACTIVATION | ACETYLATION | INTERLEUKIN-1-BETA | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | BUTYRATE | INDUCTION | DIFFERENTIATION | TRICHOSTATIN-A | Leukocytes, Mononuclear - metabolism | Mitogens - pharmacology | Concanavalin A - pharmacology | Humans | Antineoplastic Agents - administration & dosage | RNA, Messenger - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Enzyme Inhibitors - administration & dosage | Liver - injuries | Liver - drug effects | Hydroxamic Acids - administration & dosage | Antineoplastic Agents - pharmacology | Tumor Cells, Cultured | Cytokines - genetics | Hydroxamic Acids - pharmacology | Macrophages, Peritoneal - drug effects | Hepatocytes - drug effects | Interleukin-12 - biosynthesis | Nitric Oxide - biosynthesis | Leukocytes, Mononuclear - drug effects | Cytokines - metabolism | Interferon-gamma - secretion | Tumor Necrosis Factor-alpha - secretion | Cells, Cultured | Enzyme Inhibitors - pharmacology | CD3 Complex - metabolism | Cell Division - drug effects | Tumor Necrosis Factor-alpha - pharmacology | Animals | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Lipopolysaccharides - pharmacology | Leukocytes, Mononuclear - cytology | Histone Deacetylase Inhibitors | Mice, Inbred BALB C | Macrophages, Peritoneal - metabolism | Interleukin-1 - secretion | Interferon-gamma - pharmacology | Usage | Immunocytochemistry | Physiological aspects | Inflammation | Research | Liver cells | lipopolysaccharides | suberoylanilide hydroxamic acid | histone deacetylase inhibitors
Journal Article
FASEB Journal, ISSN 0892-6638, 08/2004, Volume 18, Issue 11, pp. 1318 - 1320
Interleukin-23, a recently described cytokine produced by activated antigen-presenting cells, including dendritic cells, is a p19/p40 heterodimer. The p40... 
ACTIVATION | EP2/EP4 receptors | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISTINCT | INTERLEUKIN-12 | CYTOKINE | IL-12 | MATURATION | PGE | CELL BIOLOGY | PROSTANOID RECEPTORS | inflammation | IMMUNE-RESPONSES | BIOLOGY | EXPRESSION | Toll-Like Receptor 2 | Toll-Like Receptor 4 | Arthritis - metabolism | Interleukin-12 Subunit p35 | Interleukin-12 - genetics | Interleukin-23 | Misoprostol - pharmacology | Culture Media, Conditioned - pharmacology | Male | Cell Line, Tumor - drug effects | Plasmacytoma - pathology | Interleukin-23 Subunit p19 | Alprostadil - analogs & derivatives | Cyclic AMP - physiology | Interleukins - genetics | Dendritic Cells - drug effects | Prostaglandin Antagonists - pharmacology | Receptors, Cell Surface - physiology | Interleukins - biosynthesis | Dendritic Cells - metabolism | Interleukin-12 - biosynthesis | Protein Subunits - genetics | Dinoprostone - pharmacology | Cells, Cultured - drug effects | Second Messenger Systems - drug effects | Specific Pathogen-Free Organisms | Colforsin - pharmacology | Alprostadil - pharmacology | Interleukin-17 - genetics | Inflammation | Protein Subunits - biosynthesis | Interleukin-17 - biosynthesis | Gene Expression Regulation - drug effects | Animals | Lipopolysaccharides - pharmacology | Dinoprostone - analogs & derivatives | Second Messenger Systems - physiology | Bucladesine - pharmacology | Cells, Cultured - metabolism | Mice | Dinoprostone - antagonists & inhibitors | Bone Marrow Cells - metabolism | CD4-Positive T-Lymphocytes - drug effects | Interleukin-12 Subunit p40
Journal Article