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Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2014, Volume 73, Issue 6, pp. 990 - 999
Journal Article
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 10/2015, Volume 43, Issue 4, pp. 739 - 750
Interleukin-23 (IL-23) and IL-17 are cytokines currently being targeted in clinical trials. Although inhibition of both of these cytokines is effective for... 
INFLAMMATORY-BOWEL-DISEASE | CHRONIC PLAQUE PSORIASIS | CROHNS-DISEASE | EPITHELIAL-CELLS | COLITIS | LIPOPOLYSACCHARIDE-BINDING PROTEIN | DOUBLE-BLIND | RECEPTOR COMPLEX | IMMUNOLOGY | T-CELLS | TH17 CELLS | T-Lymphocyte Subsets - immunology | Interleukin-23 Subunit p19 - antagonists & inhibitors | Intestinal Mucosa - physiopathology | ATP Binding Cassette Transporter, Sub-Family B - deficiency | Receptors, Interleukin-17 - immunology | Epithelium - physiopathology | Interleukin-17 - immunology | Interleukin-17 - physiology | Transcriptome | Helicobacter Infections - complications | Interleukin-12 Subunit p40 - antagonists & inhibitors | T-Lymphocytes, Regulatory - immunology | Receptors, Interleukin-17 - physiology | Female | Colitis - drug therapy | Colitis - immunology | Interleukin-23 - physiology | Disease Models, Animal | Gene Expression Regulation - immunology | Immunoglobulin G - therapeutic use | Helicobacter Infections - immunology | Receptors, Interleukin-17 - antagonists & inhibitors | Permeability | Disease Progression | Interleukin-23 - immunology | Mice, Knockout | Colitis - etiology | Animals | Colitis - microbiology | Forkhead Transcription Factors - analysis | Immunization, Passive | Mice | Interleukin-23 Subunit p19 - immunology | Colitis | Psoriasis | Interleukins | Drug resistance | Analysis | Mortality | Inflammatory bowel disease | Studies | Pathology | Flow cytometry | Immunoglobulins | Histopathology | Cytokines | Infections | Inflammation | Gene expression | Crohns disease
Journal Article
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 01/2012, Volume 188, Issue 2, pp. 753 - 764
Journal Article
The Journal of Immunology, ISSN 0022-1767, 09/2007, Volume 179, Issue 6, pp. 3463 - 3471
Dectin-1 is a fungal pattern recognition receptor that binds to beta-glucans and triggers cytokine production by facilitating interaction with TLR2 or by... 
BETA-GLUCAN RECEPTOR | ADAPTIVE IMMUNITY | RESPONSES | C-TYPE LECTINS | MACROPHAGE RECEPTORS | INFECTION | INDUCTION | IMMUNOLOGY | IMMUNE RECOGNITION | PATHOGEN RECOGNITION | INNATE IMMUNITY | Receptors, Immunologic - physiology | Spleen - immunology | Toll-Like Receptor 2 - genetics | Hypolipidemic Agents - metabolism | Dendritic Cells - immunology | Mycobacterium tuberculosis - immunology | Male | Stilbenes - pharmacology | Mycobacterium tuberculosis - drug effects | Interleukin-12 Subunit p40 - antagonists & inhibitors | Receptors, Immunologic - antagonists & inhibitors | Toll-Like Receptor 2 - deficiency | Membrane Proteins - physiology | Interleukin-12 - antagonists & inhibitors | Adjuvants, Immunologic - metabolism | Dendritic Cells - drug effects | Female | Membrane Proteins - metabolism | Interleukin-12 Subunit p40 - biosynthesis | Mycobacterium tuberculosis - metabolism | Syk Kinase | Dendritic Cells - metabolism | Interleukin-12 - biosynthesis | Adjuvants, Immunologic - antagonists & inhibitors | Nerve Tissue Proteins - antagonists & inhibitors | Adjuvants, Immunologic - physiology | Nerve Tissue Proteins - physiology | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Lectins, C-Type | Mice, Inbred C57BL | Spleen - cytology | Hypolipidemic Agents - pharmacology | Polysaccharides - pharmacology | Mice, Knockout | Polysaccharides - metabolism | Nerve Tissue Proteins - metabolism | Animals | Membrane Proteins - antagonists & inhibitors | Spleen - metabolism | Glucans | CD11b Antigen - physiology | Mice | Protein Kinase Inhibitors - pharmacology | Protein-Tyrosine Kinases - antagonists & inhibitors
Journal Article
Journal Article
Journal Article
Expert Opinion on Therapeutic Targets, ISSN 1472-8222, 05/2014, Volume 18, Issue 5, pp. 513 - 525
Introduction: Psoriasis is a chronic inflammatory skin disorder determined by the activation of several immune cells and resident tissue cells. Various... 
tildrakizumab | anti-p19 | biologics | psoriasis | IL-17 | IL-23 | guselkumab | Th17 | IL-23p19 | Anti-p19 | Psoriasis | Biologics | <