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PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, pp. e47463 - e47463
Human genetic background strongly influences susceptibility to malaria infection and progression to severe disease and death. Classical genetic studies... 
GLUCOSE-6-PHOSPHATE DEHYDROGENASE | TUMOR-NECROSIS-FACTOR | WEST-AFRICA | G6PD DEFICIENCY | AFRICAN CHILDREN | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY | IL-10 PRODUCTION | INFECTION | PLASMODIUM-FALCIPARUM MALARIA | ASSOCIATION | Malaria, Falciparum - genetics | Genetic Predisposition to Disease - genetics | Genes, X-Linked - genetics | Membrane Proteins - genetics | Humans | Risk Factors | Tanzania | Child, Preschool | Genotype | Infant | Logistic Models | Male | Nerve Tissue Proteins - genetics | Carrier Proteins - genetics | Interleukin-13 - genetics | CD40 Ligand - genetics | Sex Factors | Female | Interleukin-1alpha - genetics | Polymorphism, Single Nucleotide | Glucosephosphate Dehydrogenase - genetics | Adenylyl Cyclases - genetics | Child | Medical research | Malaria | Genes | Genetic research | Medicine, Experimental | Development and progression | Disease susceptibility | Genetic aspects | Single nucleotide polymorphisms | Haplotypes | Disease | Genomics | Risk | Single-nucleotide polymorphism | Males | Gene polymorphism | Epidemiology | Population genetics | CD40L protein | Tropical diseases | Red blood cells | Interleukin 1 | Population | Tumor necrosis factor-TNF | Children | Glucosephosphate dehydrogenase | Blood groups | Vector-borne diseases | Cytokines | Mortality | Health risks | Mass spectroscopy | Interleukin 13 | Gene expression | Heterozygosity | Medicine | Genotyping | Lactic acid | Mutation | Females | Acidosis | Mass spectrometry | Hygiene | Polymorphism | Index Medicus
Journal Article
Clinical and Experimental Allergy, ISSN 0954-7894, 12/2009, Volume 39, Issue 12, pp. 1875 - 1888
P>Background Common polymorphisms have been identified in genes suspected to play a role in asthma. We investigated their associations with wheeze and allergy... 
Multi-centre study | Allergy | Candidate genes | Asthma | POSITIONAL CLONING | POLYMORPHISMS | candidate genes | ECZEMA | HAPLOTYPES | allergy | RISK | asthma | PREVALENCE | IMMUNOLOGY | multi-centre study | ATOPIC SENSITIZATION | Respiratory Sounds - immunology | Eczema - genetics | Gene Frequency - genetics | Toll-Like Receptor 2 - genetics | Humans | Proteinase Inhibitory Proteins, Secretory - genetics | Tumor Necrosis Factor-alpha - genetics | Toll-Like Receptor 9 - genetics | Hypersensitivity - immunology | Serine Peptidase Inhibitor Kazal-Type 5 | Immunoglobulin E - blood | Interleukin-4 Receptor alpha Subunit - genetics | Interleukin-13 - genetics | Immunoglobulin E - immunology | Allergens - immunology | Hypersensitivity - genetics | Child | Dipeptidyl-Peptidases and Tripeptidyl-Peptidases - genetics | Respiratory Sounds - genetics | Ecuador | Guanine Nucleotide Exchange Factors - genetics | Rhinitis, Allergic, Perennial - genetics | Rhinitis, Allergic, Seasonal - genetics | Skin Tests | Genetic Association Studies | Europe | Linkage Disequilibrium - genetics | Toll-Like Receptor 4 - genetics | Transforming Growth Factor beta1 - genetics | Receptors, IgE - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Asthma - genetics | New Zealand | Asia | Lipopolysaccharide Receptors - genetics | Polymorphism, Single Nucleotide - genetics | Hypersensitivity - blood | Wheeze | Asthma in children | Analysis | Genetic research | Immunoglobulin E | Allergic reaction | Index Medicus | Allergens | Toll-Like Receptor 2 | Toll-Like Receptor 4 | Rhinitis, Allergic, Seasonal | Antigens, CD14 | Toll-Like Receptor 9 | Dipeptidyl-Peptidases and Tripeptidyl-Peptidases | Life Sciences | Eczema | Respiratory Sounds | DNA-Binding Proteins | Transforming Growth Factor beta1 | Gene Frequency | Hypersensitivity | Interleukin-13 | Interleukin-4 Receptor alpha Subunit | Tumor Necrosis Factor-alpha | Guanine Nucleotide Exchange Factors | Linkage Disequilibrium | Proteinase Inhibitory Proteins, Secretory | Receptors, IgE | Rhinitis, Allergic, Perennial | Santé publique et épidémiologie | Polymorphism, Single Nucleotide | Transcription Factors | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 12/2013, Volume 94, Issue 6, pp. 1309 - 1315
Adenosine signaling augments IL‐10‐induced STAT‐3 dependent gene expression in macrophages, suggesting its role in M2c polarization. The alternatively... 
TIMP‐1 | arginase | alternative activation | Arginase | TIMP-1 | Alternative activation | CELLS | ACTIVATION | RECEPTOR AGONISTS | IL-10 PRODUCTION | NECROSIS-FACTOR-ALPHA | IMMUNOLOGY | CELL BIOLOGY | TIMP-1 PRODUCTION | A(2B) | INFLAMMATION | TNF-ALPHA | HEMATOLOGY | EXPRESSION | Analgesics - pharmacology | Serum Amyloid A Protein - genetics | Receptor, Adenosine A2B - genetics | Interleukin-13 - genetics | Phosphorylation - genetics | Adenosine A2 Receptor Agonists - pharmacology | Serum Amyloid A Protein - biosynthesis | Phosphorylation - immunology | Phosphorylation - drug effects | Interleukin-6 - metabolism | STAT3 Transcription Factor - genetics | Interleukin-6 - genetics | Macrophage Activation - immunology | Arginase - genetics | Signal Transduction - genetics | Adenosine - pharmacology | Interleukin-13 - metabolism | Receptor, Adenosine A2B - metabolism | Mice, Knockout | Interleukin-4 - immunology | Macrophages - metabolism | Signal Transduction - drug effects | Interleukin-10 - genetics | Interleukin-6 - immunology | Mice | STAT3 Transcription Factor - immunology | Tissue Inhibitor of Metalloproteinase-1 - immunology | Interleukin-10 - immunology | Macrophage Activation - genetics | Tissue Inhibitor of Metalloproteinase-1 - biosynthesis | Interleukin-13 - immunology | Arginase - biosynthesis | Analgesics - immunology | Signal Transduction - immunology | Arginase - immunology | Receptor, Adenosine A2B - immunology | Interleukin-10 - metabolism | Interleukin-4 - genetics | Macrophages - immunology | STAT3 Transcription Factor - metabolism | Cell Line | Adenosine - immunology | Interleukin-4 - metabolism | Gene Expression Regulation | Macrophages - cytology | Serum Amyloid A Protein - immunology | Tissue Inhibitor of Metalloproteinase-1 - genetics | Animals | Aminopyridines - pharmacology | Macrophage Activation - drug effects | Index Medicus | Inflammation, Extracellular Mediators, & Effector Molecules
Journal Article
Human Genetics, ISSN 0340-6717, 9/2013, Volume 132, Issue 9, pp. 1039 - 1047
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 135, Issue 6, pp. 1594 - 1602
Background Thymic stromal lymphopoietin (TSLP) and IL-33 are considered important initiators of type 2 immunity. In asthmatic patients allergic inflammatory... 
Allergy and Immunology | Hematopoietic progenitor cells | thymic stromal lymphopoietin | asthma | BONE-MARROW | AIRWAY INFLAMMATION | INTERLEUKIN-13 | EOSINOPHIL PROGENITORS | IMMUNOLOGY | RESPONSES | FACTOR-1-ALPHA | ALLERGY | SPUTUM EOSINOPHILIA | DISEASE | EXACERBATIONS | CORTICOSTEROIDS | Interleukin-1 Receptor-Like 1 Protein | Sputum - cytology | Eosinophils - drug effects | Humans | Middle Aged | Hematopoietic Stem Cells - pathology | Interleukin-13 - immunology | Male | Interleukin-7 Receptor alpha Subunit - immunology | Interleukin-5 - genetics | Eosinophils - immunology | Forced Expiratory Volume | Interleukins - genetics | Hematopoietic Stem Cells - immunology | Interleukin-13 - genetics | Interleukin-13 Receptor alpha1 Subunit - immunology | Sputum - immunology | Chemokine CXCL12 - genetics | Interleukins - immunology | Methacholine Chloride - pharmacology | Asthma - immunology | Adult | Eosinophils - pathology | Interleukin-7 Receptor alpha Subunit - genetics | Cytokines - genetics | Receptors, Cytokine - genetics | Chemokine CXCL12 - immunology | Cytokines - immunology | Hematopoietic Stem Cells - drug effects | Interleukin-33 | Gene Expression Regulation | Administration, Inhalation | Immunity, Innate | Receptors, Cell Surface - immunology | Asthma - genetics | Interleukin-13 Receptor alpha1 Subunit - genetics | Interleukin-5 - immunology | Cell Movement - drug effects | Receptors, Cytokine - immunology | Allergens - pharmacology | Primary Cell Culture | Asthma - pathology | Receptors, Cell Surface - genetics | Care and treatment | Asthma | Studies | Flow cytometry | Airway management | Cytokines | Pathogenesis | Migration | Family medical history | Allergies | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2013, Volume 123, Issue 1, pp. 261 - 271
Hyperglycemia is a result of impaired insulin action on glucose production and disposal, and a major target of antidiabetic therapies. The study of... 
MEDICINE, RESEARCH & EXPERIMENTAL | GLUCONEOGENIC GENES | CYTOKINE RESPONSES | METABOLISM IN-VIVO | TYPE-2 IMMUNITY | MACROPHAGE POLARIZATION | CARBOHYDRATE-METABOLISM | ALTERNATIVE ACTIVATION | RECEPTOR-ALPHA | INDUCED INSULIN-RESISTANCE | ADIPOSE-TISSUE | Liver - pathology | Diabetes Mellitus, Type 2 - genetics | Interleukin-13 - immunology | Th2 Cells - immunology | Diabetes Mellitus, Type 2 - metabolism | Th1 Cells - immunology | Hyperglycemia - genetics | Th1 Cells - metabolism | Interleukin-13 - genetics | Interleukin-13 Receptor alpha1 Subunit - immunology | Liver - immunology | Diabetes Mellitus, Type 2 - immunology | Hyperglycemia - pathology | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Glucose - immunology | Liver - metabolism | Hyperglycemia - immunology | Gluconeogenesis - immunology | Glucose - genetics | Interleukin-13 - metabolism | Th2 Cells - metabolism | Mice, Knockout | Hyperglycemia - metabolism | Interleukin-13 Receptor alpha1 Subunit - genetics | Animals | Gluconeogenesis - genetics | Insulin Resistance - genetics | Glucose - metabolism | Insulin Resistance - immunology | Mice | Mice, Inbred BALB C | Diabetes Mellitus, Type 2 - pathology | STAT3 Transcription Factor - immunology | Interleukin-13 Receptor alpha1 Subunit - metabolism | Physiological aspects | Glucose metabolism | Hyperglycemia | Research | Blood sugar | Diabetes therapy | Index Medicus | Abridged Index Medicus
Journal Article
Nature Genetics, ISSN 1061-4036, 2014, Volume 46, Issue 8, pp. 895 - 900
Journal Article