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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2009, Volume 106, Issue 32, pp. 13463 - 13468
Journal Article
The Journal of Immunology, ISSN 0022-1767, 11/2009, Volume 183, Issue 10, pp. 6469 - 6477
Alternatively activated macrophages (AAM) play a crucial role in type 2 immunity. Mice deficient in ST2, a receptor for the latest member of the IL-1 family,... 
IL-1-LIKE CYTOKINE IL-33 | IMMUNE-RESPONSE | ST2 RECEPTOR | EFFECTOR FUNCTION | MAST-CELLS | IN-VIVO | INDUCED ARTHRITIS | ALVEOLAR MACROPHAGES | INTERLEUKIN-1 RECEPTOR | IMMUNOLOGY | T-CELLS | Interleukin-1 Receptor-Like 1 Protein | Asthma - metabolism | Epithelial Cells - metabolism | Ovalbumin - immunology | Humans | Middle Aged | Chemokine CCL24 - metabolism | Interleukin-13 - immunology | Male | Interleukins - metabolism | Receptors, Interleukin - metabolism | Signal Transduction - immunology | Inflammation - metabolism | Interleukins - immunology | Asthma - immunology | Chemokine CCL17 - immunology | Adult | Female | Interleukin-4 - genetics | Macrophages, Alveolar - immunology | Recombinant Proteins - metabolism | Cell Polarity - immunology | Lung - pathology | Receptors, Interleukin - immunology | Interleukin-33 | Macrophage Activation - immunology | Receptors, Interleukin-1 - immunology | Interleukin-4 - metabolism | Receptors, Interleukin-4 - metabolism | Inflammation - immunology | Receptors, Interleukin-4 - immunology | Interleukin-13 - metabolism | Chemokine CCL24 - immunology | Receptors, Interleukin - genetics | Mice, Knockout | Receptors, Interleukin-1 - metabolism | Interleukin-4 - immunology | Animals | Eosinophilia - immunology | Recombinant Proteins - immunology | Epithelial Cells - immunology | Receptors, Interleukin-4 - genetics | Mice | Mice, Inbred BALB C | Macrophages, Alveolar - metabolism | Chemokine CCL17 - metabolism | Lung - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Blood, ISSN 0006-4971, 02/2009, Volume 113, Issue 7, pp. 1526 - 1534
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2013, Volume 123, Issue 1, pp. 261 - 271
Hyperglycemia is a result of impaired insulin action on glucose production and disposal, and a major target of antidiabetic therapies. The study of... 
MEDICINE, RESEARCH & EXPERIMENTAL | GLUCONEOGENIC GENES | CYTOKINE RESPONSES | METABOLISM IN-VIVO | TYPE-2 IMMUNITY | MACROPHAGE POLARIZATION | CARBOHYDRATE-METABOLISM | ALTERNATIVE ACTIVATION | RECEPTOR-ALPHA | INDUCED INSULIN-RESISTANCE | ADIPOSE-TISSUE | Liver - pathology | Diabetes Mellitus, Type 2 - genetics | Interleukin-13 - immunology | Th2 Cells - immunology | Diabetes Mellitus, Type 2 - metabolism | Th1 Cells - immunology | Hyperglycemia - genetics | Th1 Cells - metabolism | Interleukin-13 - genetics | Interleukin-13 Receptor alpha1 Subunit - immunology | Liver - immunology | Diabetes Mellitus, Type 2 - immunology | Hyperglycemia - pathology | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Glucose - immunology | Liver - metabolism | Hyperglycemia - immunology | Gluconeogenesis - immunology | Glucose - genetics | Interleukin-13 - metabolism | Th2 Cells - metabolism | Mice, Knockout | Hyperglycemia - metabolism | Interleukin-13 Receptor alpha1 Subunit - genetics | Animals | Gluconeogenesis - genetics | Insulin Resistance - genetics | Glucose - metabolism | Insulin Resistance - immunology | Mice | Mice, Inbred BALB C | Diabetes Mellitus, Type 2 - pathology | STAT3 Transcription Factor - immunology | Interleukin-13 Receptor alpha1 Subunit - metabolism | Physiological aspects | Glucose metabolism | Hyperglycemia | Research | Blood sugar | Diabetes therapy | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Cell, ISSN 0092-8674, 2008, Volume 132, Issue 2, pp. 259 - 272
Interleukin-4 and Interleukin-13 are cytokines critical to the development of T cell-mediated humoral immune responses, which are associated with allergy and... 
MOLIMMUNO | SIGNALING | SEVERE COMBINED IMMUNODEFICIENCY | COMPLEX | ALPHA-CHAIN | JUXTAMEMBRANE DOMAIN | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMMON GAMMA-CHAIN | IL-4 RECEPTOR | THERAPEUTIC TARGETS | FUNCTIONAL COMPONENT | BINDING | CELL BIOLOGY | Phosphorylation | Receptors, Interleukin-4 - chemistry | Humans | Molecular Sequence Data | Crystallography, X-Ray | Histidine - metabolism | Receptors, Interleukin-13 - metabolism | Dose-Response Relationship, Drug | Thermodynamics | Interleukin-13 - genetics | Interleukin-4 - pharmacology | Molecular Mimicry | X-Ray Diffraction | Interleukin-13 - isolation & purification | Receptors, Interleukin-13 - chemistry | Interleukin-4 - genetics | Receptors, Cytokine - metabolism | Binding Sites | Dimerization | STAT3 Transcription Factor - metabolism | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Amino Acid Sequence | Cell Line | Protein Structure, Secondary | Signal Transduction | Interleukin-4 - metabolism | Receptors, Interleukin-4 - metabolism | Models, Molecular | STAT6 Transcription Factor - metabolism | Interleukin-13 - metabolism | Interleukin-13 - pharmacology | Sequence Homology, Amino Acid | Tyrosine - metabolism | Interleukin-4 - isolation & purification | Hydrogen Bonding | Receptors, Cytokine - chemistry | Cell Line, Tumor | Hydrophobic and Hydrophilic Interactions | Protein Binding | Ligands | Kinetics | Cytokines | Interleukins | Physiological aspects | Index Medicus
Journal Article
Nature Immunology, ISSN 1529-2908, 06/2013, Volume 14, Issue 6, pp. 564 - 573
Type 2 immunity is critical for defense against cutaneous infections but also underlies the development of allergic skin diseases. We report the identification... 
ATOPIC-DERMATITIS | TRANSCRIPTION FACTOR GATA3 | MAST-CELLS | IN-VIVO | TYPE-2 IMMUNITY | MICE | INFLUENZA-VIRUS | IMMUNOLOGY | EXPRESSION | LUNG INFLAMMATION | THYMIC STROMAL LYMPHOPOIETIN | Cell Communication - immunology | Eosinophils - metabolism | Dermatitis - immunology | Skin - metabolism | Homeodomain Proteins - metabolism | Immunity, Innate - genetics | Interleukin-17 - immunology | Interleukin-13 - immunology | Green Fluorescent Proteins - genetics | Homeodomain Proteins - immunology | Eosinophils - immunology | Flow Cytometry | Interleukin-2 - immunology | Lymphocytes - immunology | Mast Cells - metabolism | Dermis - cytology | Microscopy, Fluorescence, Multiphoton | Skin - immunology | Lymphocytes - metabolism | Green Fluorescent Proteins - metabolism | Mast Cells - immunology | Dermis - metabolism | Videotape Recording | Dermatitis - genetics | Mice, Inbred C57BL | Cells, Cultured | Mice, Transgenic | Interleukin-13 - metabolism | Dermis - immunology | Homeodomain Proteins - genetics | Mice, Knockout | Immunity, Innate - immunology | Interleukin-17 - metabolism | Animals | Lymphocytes - drug effects | Interleukin-2 - pharmacology | Mice | Mice, Inbred BALB C | Dermatitis - metabolism | Care and treatment | Development and progression | Inflammation | Genetic aspects | Research | T cells | Health aspects | Index Medicus
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 01/2013, Volume 54, pp. 1 - 16
Monocytes/macrophages are innate immune cells that play a crucial role in the resolution of inflammation. In the presence of the Th2 cytokines interleukin-4... 
Monocytes | Free radicals | Cytokines | Gene regulation | ROS | Inflammation | Alternative activation | COLLAGEN-INDUCED ARTHRITIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | INTERLEUKIN-13 | RECEPTOR | 15-LIPOXYGENASE | MONOCYTE-ENRICHED FRACTIONS | CULTURED ENDOTHELIAL-CELLS | MONOAMINE-OXIDASE-A | ENDOCRINOLOGY & METABOLISM | CENTRIFUGAL ELUTRIATION CCE | PERIPHERAL-BLOOD MONOCYTES | LDL OXIDATION | Dual Specificity Phosphatase 1 - genetics | Reactive Oxygen Species - metabolism | Macrophage Activation - immunology | Humans | Receptors, Interleukin-4 - metabolism | Cells, Cultured | Gene Expression Regulation | STAT Transcription Factors - metabolism | TYK2 Kinase - metabolism | Interleukin-13 - immunology | Monocytes - immunology | Arachidonate 15-Lipoxygenase - metabolism | Receptors, Interleukin-13 - metabolism | Interleukin-4 - immunology | Janus Kinase 1 - metabolism | Signal Transduction - immunology | Janus Kinase 2 - metabolism | Tissue Inhibitor of Metalloproteinase-3 - metabolism | Dual Specificity Phosphatase 1 - metabolism | Macrophages - immunology | Monoamine Oxidase - metabolism | Tissue Inhibitor of Metalloproteinase-3 - genetics | Tyrosine | Anopheles | Monoamine oxidase | Phosphatases | Interleukins | Genes | Genetic research | Macrophages | Gene expression | Free radicals (Chemistry) | Index Medicus | cytokines | alternative activation
Journal Article