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Journal of Controlled Release, ISSN 0168-3659, 06/2017, Volume 255, pp. 81 - 93
-forming thermosensitive hydrogels based on poly(ethylene glycol)-poly(γ-ethyl- -glutamate) diblock copolymers (mPEG- -PELG) were prepared for the co-delivery... 
ADJUVANT CHEMOTHERAPY | METASTATIC MELANOMA | LUNG-CANCER | NK CELLS | CHIMERIC-ANTIGEN-RECEPTOR | IN-VIVO | PHARMACOLOGY & PHARMACY | ANTICANCER DRUGS | SUPPRESSOR-CELLS | CHEMISTRY, MULTIDISCIPLINARY | INDUCED KILLER-CELLS | T-CELLS | Interleukin-15 - administration & dosage | Melanoma, Experimental - drug therapy | Male | Polyethylene Glycols - chemistry | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Polyethylene Glycols - therapeutic use | Peptides - administration & dosage | Cisplatin - administration & dosage | Drug Delivery Systems | Cisplatin - chemistry | Interleukin-15 - chemistry | Melanoma, Experimental - immunology | Hydrogels - administration & dosage | Antineoplastic Agents - pharmacology | Interleukin-15 - therapeutic use | Cytokines - immunology | Polyethylene Glycols - pharmacology | Cell Survival - drug effects | Peptides - chemistry | Mice, Inbred C57BL | Cisplatin - pharmacology | Antineoplastic Agents - chemistry | Rats, Sprague-Dawley | Polyethylene Glycols - administration & dosage | Peptides - pharmacology | Interleukin-15 - pharmacology | Animals | Cisplatin - therapeutic use | Cell Cycle Checkpoints - drug effects | CD8-Positive T-Lymphocytes - drug effects | Cell Line, Tumor | Drug Liberation | Killer Cells, Natural - drug effects | Hydrogels - pharmacology | Hydrogels - therapeutic use | Hydrogels - chemistry | Peptides - therapeutic use | Drugs | Ethylene glycol | Drug delivery systems | Melanoma | Antineoplastic agents | T cells | Vehicles | Antimitotic agents | Chemotherapy | Killer cells | Interleukins | Immunotherapy | Mice | Cancer | Glutamate | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2012, Volume 287, Issue 21, pp. 17152 - 17160
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2012, Volume 188, Issue 8, pp. 3745 - 3756
Journal Article
Journal Article
Blood, ISSN 0006-4971, 09/2011, Volume 118, Issue 9, pp. 2520 - 2529
Human immunodeficiency virus (HIV) infection is characterized by a progressive loss of memory CD4(+) T cells in multiple tissues, especially at mucosal... 
NONHUMAN-PRIMATES | SIMIAN IMMUNODEFICIENCY VIRUS | MEMORY CD4 | INTERLEUKIN-15 | T-CELL DEPLETION | GASTROINTESTINAL-TRACT | ANTIRETROVIRAL THERAPY | DIFFERENTIATION | HIV-1 INFECTION | HEMATOLOGY | DISEASE PROGRESSION | Interleukin-15 - administration & dosage | Deoxycytidine - pharmacology | Macaca mulatta | Viral Load | Lymphoid Tissue - immunology | CD4-Positive T-Lymphocytes - immunology | Immunity, Mucosal - drug effects | Pyrrolidinones - administration & dosage | Tenofovir | Deoxycytidine - therapeutic use | Adenine - therapeutic use | Immunotherapy | Pyrrolidinones - pharmacology | Treatment Failure | Interleukin-15 - therapeutic use | Drug Evaluation, Preclinical | Drug Therapy, Combination | Raltegravir Potassium | Interleukin-15 - adverse effects | Emtricitabine | Anti-Retroviral Agents - therapeutic use | Adenine - analogs & derivatives | Organophosphonates - therapeutic use | Lymphocyte Activation | Deoxycytidine - administration & dosage | Anti-Retroviral Agents - pharmacology | Immunologic Factors - administration & dosage | Pyrrolidinones - therapeutic use | Adenine - pharmacology | CD4 Lymphocyte Count | Random Allocation | Adenine - administration & dosage | Antiretroviral Therapy, Highly Active | Interleukin-15 - pharmacology | Lymphoid Tissue - pathology | Organophosphonates - administration & dosage | Mucous Membrane - pathology | Organophosphonates - pharmacology | Adaptive Immunity - drug effects | Animals | Mucous Membrane - immunology | Simian Acquired Immunodeficiency Syndrome - immunology | Anti-Retroviral Agents - administration & dosage | Immunologic Factors - adverse effects | CD4-Positive T-Lymphocytes - drug effects | Deoxycytidine - analogs & derivatives | Immunologic Factors - pharmacology | Immunologic Factors - therapeutic use | Immunobiology
Journal Article
Blood, ISSN 0006-4971, 12/2012, Volume 120, Issue 24, pp. 4751 - 4760
Natural killer (NK) cells are lymphocytes that play an important role in the immune response to infection and malignancy. Recent studies in mice have shown... 
INNATE | NATURAL-KILLER-CELLS | INFECTION | HEMATOLOGY | EXPANSION | Receptors, Interleukin-12 - immunology | Antigens, CD - immunology | Interleukin-18 - immunology | Humans | Lectins, C-Type - immunology | Interferon-gamma - metabolism | Interleukin-15 - immunology | Antigens, CD - metabolism | NK Cell Lectin-Like Receptor Subfamily D - immunology | Lectins, C-Type - metabolism | NK Cell Lectin-Like Receptor Subfamily C - immunology | Lymphocyte Activation - immunology | Flow Cytometry | Time Factors | Killer Cells, Natural - immunology | Receptors, Interleukin-12 - genetics | Interferon-gamma - genetics | CD56 Antigen - immunology | Immunologic Memory - immunology | Cytokines - immunology | Interleukin-12 - pharmacology | Receptors, Interleukin-18 - metabolism | CD56 Antigen - metabolism | NK Cell Lectin-Like Receptor Subfamily C - metabolism | Antigens, Differentiation, T-Lymphocyte - immunology | Antigens, Differentiation, T-Lymphocyte - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Interleukin-15 - pharmacology | Receptors, Interleukin-12 - metabolism | Lymphocyte Activation - drug effects | Interferon-gamma - immunology | Interleukin-12 - immunology | K562 Cells | Receptors, Interleukin-18 - genetics | Receptors, Interleukin-18 - immunology | Cell Proliferation - drug effects | Interleukin-18 - pharmacology | Killer Cells, Natural - drug effects | Killer Cells, Natural - metabolism | NK Cell Lectin-Like Receptor Subfamily D - metabolism | Cytokines - pharmacology | Immunobiology
Journal Article
American Journal of Clinical Nutrition, ISSN 0002-9165, 10/2013, Volume 98, Issue 4, pp. 1123 - 1135
Background: On ingestion of gliadin, the major protein component of wheat and other cereals, the celiac intestine is characterized by the proliferation of... 
GROWTH-FACTOR RECEPTOR | CELLS | RESPONSES | ONCOGENE | NUTRITION & DIETETICS | HORMONE | PROTEIN | INTERLEUKIN-15 | GENES | DIFFERENTIATION | CANCER | Interleukin-15 - physiology | RNA, Small Interfering - genetics | Receptor, Epidermal Growth Factor - genetics | Phosphorylation | Interleukin-15 Receptor alpha Subunit - antagonists & inhibitors | Epidermal Growth Factor - physiology | Humans | Peptide Fragments - pharmacology | Transfection | Celiac Disease - immunology | Peptide Fragments - immunology | Enterocytes - pathology | Receptor, Epidermal Growth Factor - physiology | Caco-2 Cells | Gliadin - immunology | Epidermal Growth Factor - genetics | Interleukin-15 Receptor alpha Subunit - physiology | Cells, Cultured | RNA, Small Interfering - physiology | Interleukin-15 Receptor alpha Subunit - genetics | Immunity, Innate | Enterocytes - immunology | Antibodies - pharmacology | Gene Expression Regulation - drug effects | Celiac Disease - pathology | Interleukin-15 - pharmacology | Interleukin-15 - genetics | Signal Transduction - drug effects | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Signal Transduction - physiology | Cell Proliferation - drug effects | Epidermal Growth Factor - pharmacology | Gliadin - pharmacology | Celiac disease | Care and treatment | Epidermal growth factor | Diagnosis | Analysis | Risk factors
Journal Article
International Immunology, ISSN 0953-8178, 12/2004, Volume 16, Issue 12, pp. 1769 - 1780
Naturally occurring CD4(+)CD25(+) regulatory T (T-R) cells play crucial roles in normal immunohomeostasis. CD4(+)CD25(+) T-R cells exhibit a number of... 
CD4 | Regulation | CD25 | Anergy | LPS | SUPPRESSOR | IMMUNITY | RECEPTOR | ALPHA | INDUCTION | IMMUNOLOGY | GENE-EXPRESSION ANALYSIS | anergy | IL-2 PRODUCTION | regulation | CD25+CD4+T-R | IMMUNOREGULATORY T-CELLS | IN-VIVO | IMMUNOLOGICAL SELF-TOLERANCE | Interleukin-15 - physiology | T-Lymphocyte Subsets - immunology | Dendritic Cells - immunology | Bone Marrow Cells - physiology | DNA-Binding Proteins - analysis | Lipopolysaccharides - immunology | Clonal Anergy - physiology | T-Lymphocytes, Regulatory - immunology | DNA-Binding Proteins - metabolism | B7-2 Antigen | Lymphocyte Activation - immunology | Membrane Glycoproteins - physiology | T-Lymphocyte Subsets - drug effects | Interleukin-6 - physiology | Bone Marrow Cells - drug effects | Dendritic Cells - drug effects | Polysaccharides, Bacterial - pharmacology | CD4 Antigens - immunology | Membrane Glycoproteins - pharmacology | Homeostasis - immunology | Polysaccharides, Bacterial - immunology | DNA-Binding Proteins - genetics | Receptors, Interleukin-2 - immunology | Mice, Knockout | Salmonella enteritidis - immunology | Interleukin-15 - pharmacology | Interleukin-2 - genetics | T-Lymphocytes, Regulatory - drug effects | Animals | Interleukin-6 - pharmacology | Lipopolysaccharides - pharmacology | Clonal Anergy - immunology | Interleukin-2 - pharmacology | Antigens, CD - pharmacology | Antigens, CD - physiology | Mice | Interleukin-2 - biosynthesis | Forkhead Transcription Factors | Lymphocyte Activation - physiology | Receptors, Interleukin-2 - analysis
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 11/2009, Volume 183, Issue 10, pp. 6639 - 6645
We determined whether human NK cells could contribute to immune defenses against Mycobacterium tuberculosis through production of IL-22. CD3(-)CD56(+) NK cells... 
T(H)17 CYTOKINE | NATURAL-KILLER-CELLS | ROR-GAMMA-T | INTERFERON-GAMMA | HUMAN MACROPHAGES | MUCOSAL HOST-DEFENSE | NECROSIS-FACTOR-ALPHA | INTRACELLULAR BACTERIUM | IMMUNOLOGY | HUMAN MONOCYTES | INNATE IMMUNITY | Phagosomes - microbiology | RNA, Messenger - immunology | Humans | Mycobacterium tuberculosis - immunology | Tuberculosis - microbiology | RNA, Messenger - metabolism | Mycobacterium tuberculosis - drug effects | Interleukins - metabolism | Phagosomes - immunology | RNA, Small Interfering - immunology | Receptors, Immunologic - agonists | Interleukins - immunology | Killer Cells, Natural - immunology | Interleukins - pharmacology | Receptors, Immunologic - immunology | Macrophages - immunology | Macrophages - microbiology | Interleukin-12 - pharmacology | Killer Cells, Natural - microbiology | Phagosomes - drug effects | Phagosomes - metabolism | Recombinant Proteins - pharmacology | RNA, Messenger - agonists | Tuberculosis - immunology | Interleukin-15 - pharmacology | Macrophages - metabolism | Interleukin-23 - pharmacology | Macrophages - drug effects | Interleukin-18 - pharmacology | Killer Cells, Natural - drug effects | Killer Cells, Natural - metabolism | Receptors, Immunologic - genetics | Receptors, Immunologic - metabolism | Mycobacterium tuberculosis - growth & development | RNA, Small Interfering - metabolism
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 08/2011, Volume 17, Issue 16, pp. 5343 - 5352
Journal Article
International Immunology, ISSN 0953-8178, 6/2007, Volume 19, Issue 6, pp. 785 - 799
CD4+CD25+ regulatory T cells (Tregs) have far-reaching immunotherapeutic applications, the realization of which will require a greater understanding of the... 
LY294002 | Phosphatidylinositol 3-kinase | Common gamma chain | FOXP3 | ANTIGEN 4 | INTERLEUKIN (IL)-2 | SIGNALING PATHWAYS | ACTIVATION | common gamma chain | REG-CELLS | IMMUNOLOGY | GENE-EXPRESSION | CD4(+) | IMMUNOLOGICAL SELF-TOLERANCE | AUTOIMMUNE-DISEASE | phosphatidylinositol 3-kinase | T-Lymphocytes, Regulatory - metabolism | Apoptosis - drug effects | Cyclosporine - pharmacology | Coculture Techniques | Humans | Interleukin-7 - pharmacology | Receptors, Nerve Growth Factor - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Receptors, Antigen, T-Cell - antagonists & inhibitors | Antigens, CD - metabolism | CD4-Positive T-Lymphocytes - immunology | Interleukin-4 - pharmacology | Flow Cytometry | Forkhead Transcription Factors - metabolism | Immune Tolerance - immunology | Antigens, Differentiation - metabolism | Phosphorylation - drug effects | Chromones - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | HLA-DR Antigens - metabolism | Immune Tolerance - drug effects | T-Lymphocytes, Regulatory - physiology | Receptors, Tumor Necrosis Factor - metabolism | CD4-Positive T-Lymphocytes - metabolism | Glucocorticoid-Induced TNFR-Related Protein | Morpholines - pharmacology | Blotting, Western | CTLA-4 Antigen | Interleukin-15 - pharmacology | T-Lymphocytes, Regulatory - drug effects | Interleukin-2 Receptor alpha Subunit - metabolism | Interleukin-6 - pharmacology | Interleukin-2 - pharmacology | Interleukin-2 Receptor alpha Subunit - analysis | Cell Proliferation - drug effects | CD4-Positive T-Lymphocytes - drug effects
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 10/2017, Volume 77, Issue 20, pp. 5664 - 5675
Journal Article