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Journal of neuroimmunology, ISSN 0165-5728, 2008, Volume 194, Issue 1-2, pp. 54 - 61
Abstract Interleukin (IL)-17-producing helper T cells may play a pivotal role in the pathogenesis of multiple sclerosis. Here, we examined the effects of IL-17... 
Neurology | Allergy and Immunology | EAE | Cytokine | IL-17 | Microglia | MS | cytokine | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | MULTIPLE-SCLEROSIS LESIONS | MESSENGER-RNA EXPRESSION | NEUROTROPHIC FACTOR | IMMUNOLOGY | NEUROSCIENCES | NERVE GROWTH-FACTOR | INTERLEUKIN-17 | NEURONAL DEATH | NITRIC-OXIDE | TNF-ALPHA | microglia | T-CELLS | Brain-Derived Neurotrophic Factor - genetics | Microglia - metabolism | Humans | Tumor Necrosis Factor-alpha - genetics | Interleukin-17 - physiology | Receptors, Interleukin-17 - genetics | Interleukin-17 - pharmacology | Interleukin-1beta - genetics | Interleukin-23 - genetics | RNA, Messenger - biosynthesis | Chemokine CXCL2 - genetics | Brain-Derived Neurotrophic Factor - biosynthesis | Interleukin-1beta - biosynthesis | Multiple Sclerosis - metabolism | Autocrine Communication | Nitric Oxide - biosynthesis | Cells, Cultured - drug effects | Interleukin-6 - genetics | Microglia - drug effects | Receptors, Interleukin-17 - biosynthesis | Glial Cell Line-Derived Neurotrophic Factor - biosynthesis | Glial Cell Line-Derived Neurotrophic Factor - genetics | Interleukin-17 - biosynthesis | Recombinant Proteins - pharmacology | Gene Expression Regulation - drug effects | Up-Regulation - drug effects | Animals | Interleukin-23 - biosynthesis | Interleukin-6 - biosynthesis | Cells, Cultured - metabolism | Chemokine CXCL2 - biosynthesis | Mice | Tumor Necrosis Factor-alpha - biosynthesis | Multiple sclerosis | Interleukins | T cells | Nitric oxide
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 2008, Volume 181, Issue 10, pp. 7420 - 7427
Journal Article
Journal Article
Cell (Cambridge), ISSN 0092-8674, 2015, Volume 163, Issue 6, pp. 1413 - 1427
Journal Article
Infection and Immunity, ISSN 0019-9567, 04/2012, Volume 80, Issue 4, pp. 1437 - 1444
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 2010, Volume 185, Issue 3, pp. 1959 - 1967
Journal Article
PLoS pathogens, ISSN 1553-7374, 2012, Volume 8, Issue 7, p. e1002771
Vaccines may help reduce the growing incidence of fungal infections in immune-suppressed patients. We have found that, even in the absence of CD4(+) T-cell... 
DEFENSE | ACTIVATION | MICROBIOLOGY | IL-23 | DECTIN-1 | RESPONSES | PNEUMOCYSTIS-CARINII | VIROLOGY | INTERLEUKIN-17 | IL-17 | PARASITOLOGY | TH17 CELLS | ANTIGEN | Lung - microbiology | Receptors, CCR6 - biosynthesis | Interleukin-17 - immunology | Fungal Vaccines - immunology | Blastomycosis - immunology | Lung Diseases, Fungal - microbiology | Histoplasmosis - immunology | CD4-Positive T-Lymphocytes - immunology | Lectins, C-Type - metabolism | Histoplasma - pathogenicity | Receptors, Immunologic - biosynthesis | Receptors, CCR6 - metabolism | Pneumonia - immunology | Blastomyces - pathogenicity | Immunologic Deficiency Syndromes - immunology | Immunologic Memory - immunology | Interleukin-12 - biosynthesis | Lung Diseases, Fungal - immunology | Signal Transduction | Mice, Inbred C57BL | Receptors, CXCR3 - biosynthesis | Hepatocyte Nuclear Factor 1-alpha | Neutrophils - immunology | Pneumonia - microbiology | Interleukin-17 - biosynthesis | Mice, Knockout | Histoplasma - immunology | Cell Differentiation - immunology | T Cell Transcription Factor 1 - biosynthesis | Animals | Interleukin-6 - immunology | Interleukin-6 - biosynthesis | Th17 Cells - immunology | Blastomyces - immunology | Mice | Immunocompromised Host | CD8-Positive T-Lymphocytes - immunology | Lung - immunology | Fungi | Medical research | Flow cytometry | Pneumonia | Cytokines | Lymphocytes | Rodents | Cytotoxicity | Vaccines | Fungal infections | Experiments
Journal Article
PloS one, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, p. e0148826
CD4+ T regulatory cells (Tregs) comprise a heterogeneous population of cells the regulate immune responses and prevent autoimmunity. Most reports on human... 
ALLERGIC RHINITIS | HOMEOSTASIS | HELIOS | CTLA-4 | MULTIDISCIPLINARY SCIENCES | IN-VIVO | Respiratory System - pathology | Interferons - biosynthesis | Leukocyte Common Antigens - metabolism | Antigens, CD - biosynthesis | Humans | Middle Aged | Leukocyte Common Antigens - biosynthesis | Ikaros Transcription Factor - biosynthesis | Male | Integrin alpha2 - metabolism | Antigens, CD - metabolism | Young Adult | Flow Cytometry | Forkhead Transcription Factors - metabolism | T-Lymphocytes, Regulatory - cytology | Interleukin-10 - metabolism | Adult | Female | Nasal Mucosa - metabolism | Ikaros Transcription Factor - metabolism | Interleukin-2 - metabolism | Forkhead Transcription Factors - biosynthesis | CD4-Positive T-Lymphocytes - cytology | Interleukin-17 - biosynthesis | Interleukin-17 - metabolism | Phenotype | Adolescent | Interferons - metabolism | Interleukin-10 - biosynthesis | Leukocytes, Mononuclear - cytology | Interleukin-2 - biosynthesis | Integrin alpha2 - biosynthesis | Autoimmunity | Cytokines | T cells | Analysis | Transcription factors | Authorship | Mucosa | Homeostasis | Otolaryngology | Lymphocytes T | Blood | Thymus | Respiratory tract | CTLA-4 protein | Interleukin 2 | Lymphocytes | Immunotherapy | Rodents | Peripheral blood | Foxp3 protein | Immune system | Antigens | Memory cells | Immune response | Immunoregulation | Immunomodulation | Inflammation | Allergies | Interleukin 17 | CD4 antigen | Studies | Pathology | Interleukin 10 | Interferon
Journal Article
The Journal of Immunology, ISSN 0022-1767, 06/2006, Volume 176, Issue 12, pp. 7768 - 7774
IL-23 is a heterodimeric cytokine comprising a p19 subunit associated with the IL-12/23p40 subunit. Like IL-12, IL-23 is expressed predominantly by activated... 
GAMMA | INFLAMMATION | DISTINCT | INTERLEUKIN-12 | P19 | CYTOKINE | INDUCTION | IMMUNOLOGY | T-CELLS | LESIONS | DISEASE-ACTIVITY | Interleukin-12 Subunit p35 | Interleukin-12 - genetics | Dendritic Cells - immunology | Humans | Interleukin-23 | Middle Aged | Oligonucleotides, Antisense - metabolism | Dendritic Cells - pathology | Monocytes - metabolism | Monocytes - immunology | Interleukin-23 Subunit p19 | CD4-Positive T-Lymphocytes - immunology | Cell Differentiation - genetics | Interleukins - genetics | RNA, Messenger - biosynthesis | Lymphocyte Activation - immunology | Transfection | Interleukin-12 - antagonists & inhibitors | Monocytes - pathology | Adult | Interleukins - biosynthesis | Dendritic Cells - metabolism | Interleukin-12 - biosynthesis | Protein Subunits - genetics | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Antigen Presentation - genetics | Immunophenotyping | Up-Regulation - genetics | Protein Subunits - biosynthesis | Interleukin-17 - biosynthesis | Interleukins - antagonists & inhibitors | Cell Differentiation - immunology | Oligonucleotides, Antisense - chemical synthesis | Up-Regulation - immunology | Multiple Sclerosis - immunology | Interleukin-10 - biosynthesis | Protein Subunits - antagonists & inhibitors | Tumor Necrosis Factor-alpha - biosynthesis | Tumor Necrosis Factor-alpha - antagonists & inhibitors
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 2002, Volume 169, Issue 10, pp. 5897 - 5903
textabstractHerpetic stromal keratitis (HSK) is an immunopathologic disease triggered by infection of the cornea with HSV. Key events in HSK involve the... 
Interleukin-8/physiology/secretion | Cell Line | Fibroblasts/enzymology/immunology/metabolism/secretion | Cornea/immunology/metabolism/pathology | Humans | Recombinant Proteins/biosynthesis | Tumor Necrosis Factor-alpha/pharmacology | Cells, Cultured | Neutrophil Infiltration/immunology | Keratitis, Herpetic/immunology/pathology | Drug Synergism | Chemokines/biosynthesis/secretion | Interleukin-6/secretion | Interstitial Collagenase/secretion | Research Support, Non-U.S. Gov't | Stromal Cells/immunology/metabolism/pathology | Adjuvants, Immunologic/biosynthesis/metabolism/pharmacology/physiology | Interleukin-17/biosynthesis/metabolism/pharmacology/physiology | Receptors, Interleukin/biosynthesis | T-Lymphocyte Subsets/immunology/metabolism/pathology | SIMPLEX VIRUS | EPITHELIAL-CELLS | INTERFERON-GAMMA | IFN-GAMMA | GENE-EXPRESSION | NECROSIS-FACTOR-ALPHA | TNF-ALPHA | PROINFLAMMATORY CYTOKINES | IMMUNOLOGY | HUMAN KERATINOCYTES | NEUTROPHIL RECRUITMENT | T-Lymphocyte Subsets - immunology | Fibroblasts - enzymology | Receptors, Interleukin - biosynthesis | Adjuvants, Immunologic - pharmacology | Stromal Cells - pathology | Cornea - immunology | Interleukin-17 - physiology | Interleukin-8 - physiology | Keratitis, Herpetic - immunology | Interleukin-17 - pharmacology | Receptors, Interleukin-17 | Recombinant Proteins - biosynthesis | Keratitis, Herpetic - pathology | Adjuvants, Immunologic - metabolism | Cornea - pathology | Interleukin-8 - metabolism | Interleukin-6 - metabolism | Fibroblasts - metabolism | Neutrophil Infiltration - immunology | Adjuvants, Immunologic - physiology | Chemokines - biosynthesis | Stromal Cells - metabolism | Stromal Cells - immunology | Adjuvants, Immunologic - biosynthesis | Interleukin-17 - biosynthesis | Cornea - metabolism | Interleukin-17 - metabolism | Tumor Necrosis Factor-alpha - pharmacology | T-Lymphocyte Subsets - pathology | T-Lymphocyte Subsets - metabolism | Fibroblasts - immunology | Chemokines - metabolism | Matrix Metalloproteinase 1 - metabolism
Journal Article
The Journal of immunology (1950), ISSN 0022-1767, 10/2013, Volume 191, Issue 8, pp. 4431 - 4439
Journal Article