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Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 08/2015, Volume 112, Issue 34, pp. 10768 - 10773
Th17 responses are critical to a variety of human autoimmune diseases, and therapeutic targeting with monoclonal antibodies against IL-17 and IL-23 has shown... 
Epigenetic inhibitors | Bromodomain | Th17 | CBP/p300 | Ankylosing spondylitis | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | p300-CBP Transcription Factors - antagonists & inhibitors | Humans | Middle Aged | Crystallography, X-Ray | Male | Structure-Activity Relationship | Benzimidazoles - chemistry | Th17 Cells - drug effects | Arthritis, Psoriatic - pathology | Adult | Female | Molecular Structure | Drug Evaluation, Preclinical | Immunosuppressive Agents - pharmacology | Arthritis, Psoriatic - metabolism | Recombinant Proteins - metabolism | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Interleukin-17 - genetics | Models, Molecular | Interleukin-17 - biosynthesis | Isoxazoles - chemistry | Spondylitis, Ankylosing - metabolism | Azepines - pharmacology | Gene Expression Regulation - drug effects | Isoxazoles - pharmacology | Triazoles - pharmacology | Interleukin-17 - metabolism | Th17 Cells - immunology | Benzimidazoles - pharmacology | Calorimetry | Protein Conformation | Aged | Kinetics | Spondylitis, Ankylosing - pathology | CD4-Positive T-Lymphocytes - drug effects | Immunosuppressive Agents - chemistry | Protein Structure, Tertiary - drug effects | Immune response | Development and progression | Genetic aspects | Genetic transcription | Binding proteins | Properties | Autoimmune diseases | Health aspects | Index Medicus | CBP | p300 | Biological Sciences | bromodomain | epigenetic inhibitors | ankylosing spondylitis
Journal Article
Gut, ISSN 1468-3288, 03/2020, Volume 69, Issue 3, pp. 578 - 590
Objective The functional role of interleukin-22 (IL22) in chronic inflammation is controversial, and mechanistic insights into how it regulates target tissue... 
ER stress | Interleukin 22 | inflammatory bowel disease | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Transcription, Genetic - drug effects | Apoptosis - drug effects | Colitis - genetics | Humans | Ustekinumab - pharmacology | Apoptosis - genetics | Colitis - pathology | Interleukin-17 - pharmacology | Endoplasmic Reticulum Stress - genetics | Epithelial Cells - physiology | Interleukins - genetics | Organoids | Colitis - blood | Interleukin-23 - antagonists & inhibitors | Phenylbutyrates - pharmacology | Colitis - drug therapy | Interleukins - pharmacology | Disease Models, Animal | Cell Survival - drug effects | Endoplasmic Reticulum Stress - drug effects | Interleukins - blood | Colon - pathology | Recombinant Proteins - pharmacology | Unfolded Protein Response | Ustekinumab - therapeutic use | Patient Acuity | Gastrointestinal Agents - pharmacology | Animals | Crohn Disease - pathology | Tunicamycin - pharmacology | Gastrointestinal Agents - therapeutic use | Anti-Bacterial Agents - pharmacology | Crohn Disease - physiopathology | Mice | Chronic Disease | Intestinal Mucosa - pathology | Restitution | Ontology | Disease | Transcription | Peptides | Epithelial cells | Interleukin 23 | Genomes | Inflammatory diseases | Datasets | Proteins | Interleukin 1 | Colon | Stress response | Cytokines | Interleukin 12 | Inflammation | Gene expression | Pathogenicity | Inflammatory bowel disease | Molecular modelling | Colitis | Endoplasmic reticulum | Cellular stress response | Index Medicus | Abridged Index Medicus | 1239 | Recent Advances in Basic Science | 2312 | 1506
Journal Article
PloS one, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, pp. e0175153 - e0175153
IL-1 beta is a potent player in cutaneous inflammation and central for the development of a Th17 micro-milieu in autoinflammatory diseases including psoriasis.... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Caspases - immunology | Humans | Interleukin-17 - immunology | Interleukin-17 - pharmacology | Interleukin-1beta - genetics | S100 Proteins - immunology | Psoriasis - genetics | S100 Proteins - genetics | Th17 Cells - drug effects | Transfection | Inflammasomes - drug effects | Psoriasis - pathology | Adaptor Proteins, Signal Transducing - immunology | Apoptosis Regulatory Proteins - genetics | Skin - pathology | Skin - immunology | Th17 Cells - pathology | Interleukin-1beta - secretion | Psoriasis - immunology | S100 Calcium Binding Protein A7 | Apoptosis Regulatory Proteins - immunology | DNA - immunology | Signal Transduction | Caspases - genetics | Cells, Cultured | Gene Expression Regulation | Interleukin-17 - genetics | Interleukin-1beta - immunology | Vitamin D - pharmacology | Keratinocytes - cytology | Keratinocytes - immunology | DNA - genetics | Interleukin-17 - antagonists & inhibitors | Keratinocytes - drug effects | Inflammasomes - immunology | Adaptor Proteins, Signal Transducing - genetics | Th17 Cells - immunology | Interferon-gamma - pharmacology | Interleukins | Physiological aspects | Development and progression | Skin diseases | Genetic aspects | Inflammation | Research | Cell culture | Transcription | Interleukin | Helper cells | Lymphocytes T | Inflammatory diseases | Vitamin D | Lymphocytes | Interleukin 1 | Lesions | Deoxyribonucleic acid--DNA | Psoriasis | Cytokines | Dermatology | Keratinocytes | Caspase | Epidermis | Hazards | Gene expression | Caspase-5 | Hospitals | Biopsy | Interferon | Autoimmune diseases | Apoptosis | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Arthritis research & therapy, ISSN 1478-6354, 2013, Volume 15, Issue 5, pp. R151 - R151
Journal Article
Nutrition (Burbank, Los Angeles County, Calif.), ISSN 0899-9007, 02/2016, Volume 32, Issue 2, pp. 174 - 178
Abstract Flavonoid resveratrol modulates the transcription factor NF-κB; inhibits the cytochrome P450 isoenzyme CYP1 A1; suppresses the expression and activity... 
Gastroenterology and Hepatology | Obesity | Flavonoids | Microbiota | Type 2 diabetes mellitus | Alzheimer's disease | Resveratrol | Life Sciences & Biomedicine | Nutrition & Dietetics | Science & Technology | Autistic Disorder - chemically induced | Tumor Necrosis Factor-alpha - metabolism | Brain-Derived Neurotrophic Factor - genetics | Apoptosis - drug effects | Humans | Tumor Necrosis Factor-alpha - genetics | Cytochrome P-450 CYP1A1 - antagonists & inhibitors | Hypoxia-Inducible Factor 1, alpha Subunit - antagonists & inhibitors | Lipoxins - pharmacology | NF-kappa B - metabolism | Vascular Endothelial Growth Factor A - metabolism | Stilbenes - pharmacology | Metabolic Syndrome - chemically induced | Vascular Endothelial Growth Factor A - genetics | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Brain-Derived Neurotrophic Factor - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Diabetes Mellitus, Type 2 - prevention & control | Gastrointestinal Tract - microbiology | Interleukin-17 - genetics | Gastrointestinal Tract - drug effects | Antioxidants - pharmacology | Autistic Disorder - prevention & control | Transcription Factors - genetics | Cytochrome P-450 CYP1A1 - metabolism | Transcription Factors - metabolism | Interleukin-17 - metabolism | Gastrointestinal Microbiome - drug effects | Interleukin-17 - antagonists & inhibitors | NF-kappa B - genetics | Cell Differentiation - drug effects | Metabolic Syndrome - prevention & control | Cell Proliferation - drug effects | Diabetes Mellitus, Type 2 - chemically induced | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Type 2 diabetes | COX-2 inhibitors | Bisphenol-A | Endothelial growth factors | Microbiota (Symbiotic organisms) | Cytochrome P-450 | Schizophrenia | Bipolar disorder | T cells | Cell differentiation | Fatty acids | Autism | Stem cells | Tumor proteins | Pathogenesis | p53 Protein | Lipids | Proteins | Antioxidants | Signal transduction | Lymphocytes | Rodents | Oxidation | Growth factors | Cytochromes P450 | Diabetes mellitus | Rapamycin | Metabolism | Bisphenol A | Alloxan | Brain-derived neurotrophic factor | Insulin resistance | Hypoxia | Diabetes | Alzheimers disease | Autoimmune diseases | Metabolic disorders | Dementia | Apoptosis | Tumors | Index Medicus
Journal Article