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Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 135, Issue 6, pp. 1476 - 1485.e7
Background Chronic rhinosinusitis (CRS) with nasal polyps (NPs) in Western populations is associated with TH 2 cytokine polarization. IL-25, an IL-17 family... 
Allergy and Immunology | sinusitis | allergy | animal models | IL-25 | Nasal polyp | SKIN BARRIER DYSFUNCTION | MAST-CELLS | CYTOKINE | INNATE LYMPHOID-CELLS | IMMUNOLOGY | ATOPIC-DERMATITIS | RESPONSES | INTERLEUKIN-17 FAMILY | INFLAMMATION | MOUSE MODEL | IN-VIVO | Eosinophil Cationic Protein - genetics | Eosinophils - drug effects | Humans | Middle Aged | Male | Receptors, Interleukin-17 - genetics | Eosinophils - immunology | Rhinitis - drug therapy | Eosinophil Cationic Protein - immunology | Transforming Growth Factor beta2 - immunology | Sinusitis - genetics | Gene Expression - immunology | Eosinophils - pathology | Disease Models, Animal | Nuclear Receptor Subfamily 1, Group F, Member 3 - immunology | Antibodies, Monoclonal - pharmacology | Neutrophils - drug effects | Interleukin-17 - genetics | Rhinitis - complications | Mice | Chronic Disease | Sinusitis - drug therapy | GATA3 Transcription Factor - genetics | Cell Adhesion Molecules - genetics | Gene Expression - drug effects | GATA3 Transcription Factor - immunology | Receptors, Interleukin-17 - immunology | Interleukin-17 - immunology | T-Box Domain Proteins - immunology | Cell Adhesion Molecules - immunology | Case-Control Studies | Sinusitis - complications | Transforming Growth Factor beta1 - immunology | Sinusitis - immunology | Nasal Polyps - genetics | Adult | Female | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Neutrophils - pathology | Nasal Polyps - immunology | Rhinitis - immunology | Neutrophils - immunology | Transforming Growth Factor beta1 - genetics | Nasal Polyps - drug therapy | T-Box Domain Proteins - genetics | Rhinitis - genetics | Animals | Nasal Polyps - complications | Interleukin-17 - antagonists & inhibitors | Transforming Growth Factor beta2 - genetics | Medical colleges | Nurse practitioners | Nasal polyps | Atopic dermatitis | Health aspects | Proteins | Immunoglobulins | Pulmonary fibrosis | Disease | Laboratories | Rodents | Surgery | Family medical history | Endoscopy | Quality of life | Index Medicus | Abridged Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 10/2015, Volume 43, Issue 4, pp. 739 - 750
Interleukin-23 (IL-23) and IL-17 are cytokines currently being targeted in clinical trials. Although inhibition of both of these cytokines is effective for... 
INFLAMMATORY-BOWEL-DISEASE | CHRONIC PLAQUE PSORIASIS | CROHNS-DISEASE | EPITHELIAL-CELLS | COLITIS | LIPOPOLYSACCHARIDE-BINDING PROTEIN | DOUBLE-BLIND | RECEPTOR COMPLEX | IMMUNOLOGY | T-CELLS | TH17 CELLS | T-Lymphocyte Subsets - immunology | Interleukin-23 Subunit p19 - antagonists & inhibitors | Intestinal Mucosa - physiopathology | ATP Binding Cassette Transporter, Sub-Family B - deficiency | Receptors, Interleukin-17 - immunology | Epithelium - physiopathology | Interleukin-17 - immunology | Interleukin-17 - physiology | Transcriptome | Helicobacter Infections - complications | Interleukin-12 Subunit p40 - antagonists & inhibitors | T-Lymphocytes, Regulatory - immunology | Receptors, Interleukin-17 - physiology | Female | Colitis - drug therapy | Colitis - immunology | Interleukin-23 - physiology | Disease Models, Animal | Gene Expression Regulation - immunology | Immunoglobulin G - therapeutic use | Helicobacter Infections - immunology | Receptors, Interleukin-17 - antagonists & inhibitors | Permeability | Disease Progression | Interleukin-23 - immunology | Mice, Knockout | Colitis - etiology | Animals | Colitis - microbiology | Forkhead Transcription Factors - analysis | Immunization, Passive | Mice | Interleukin-23 Subunit p19 - immunology | Colitis | Psoriasis | Interleukins | Drug resistance | Analysis | Mortality | Inflammatory bowel disease | Studies | Pathology | Flow cytometry | Immunoglobulins | Histopathology | Cytokines | Infections | Inflammation | Gene expression | Crohns disease | Index Medicus
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 05/2017, Volume 41, Issue 3, pp. 960 - 972
Background/Aims: Interleukin (IL)-17A, a proinflammatory cytokine, has been implicated in several autoimmune diseases. However, it is unclear whether IL-17A is... 
Retinal Müller cells | Diabetic retinopathy | Interleukin-17A | Interleukin-17 receptor A | ACTIVATION | PHYSIOLOGY | NEURODEGENERATION | DEGENERATION | CELL BIOLOGY | INTRAVITREAL INJECTION | RETINAL GANGLION-CELLS | INTERLEUKIN-17 | INFLAMMATION | Retinal Muller cells | MOUSE MODEL | EXPRESSION | T-CELLS | Retina - drug effects | Glial Fibrillary Acidic Protein - genetics | Intravitreal Injections | Streptozocin | Receptors, Interleukin-17 - immunology | Interleukin-17 - immunology | Male | Receptors, Interleukin-17 - genetics | Retina - immunology | Diabetic Retinopathy - pathology | Glial Fibrillary Acidic Protein - immunology | Excitatory Amino Acid Transporter 1 - genetics | Vascular Endothelial Growth Factor A - genetics | Diabetic Retinopathy - chemically induced | Diabetes Mellitus, Experimental - chemically induced | Ependymoglial Cells - pathology | Diabetic Retinopathy - immunology | Signal Transduction | Antibodies, Monoclonal - pharmacology | Mice, Inbred C57BL | Gene Expression Regulation | Interleukin-17 - genetics | Vascular Endothelial Growth Factor A - immunology | Receptors, Interleukin-17 - antagonists & inhibitors | Diabetic Retinopathy - therapy | Ependymoglial Cells - drug effects | Ependymoglial Cells - immunology | Diabetes Mellitus, Experimental - immunology | Glutamate-Ammonia Ligase - immunology | Animals | Interleukin-17 - antagonists & inhibitors | Glutamate-Ammonia Ligase - genetics | Excitatory Amino Acid Transporter 1 - immunology | Diabetes Mellitus, Experimental - pathology | Immunization, Passive | Mice | Retina - pathology | Immunoglobulins | Cytokines | Research & development--R&D | Retina | Permeability | Gene expression | Kinases | Hyperglycemia | Rodents | Diabetes | Vascular endothelial growth factor | Apoptosis | Index Medicus
Journal Article
Journal Article
Cell Reports, ISSN 2211-1247, 08/2017, Volume 20, Issue 7, pp. 1667 - 1680
The interleukin 17 (IL-17) cytokine and receptor family is central to antimicrobial resistance and inflammation in the lung. Mice lacking IL-17A, IL-17F, or... 
IL-17F/IL-17RC axis | Th17 immunity | allergy | ABPA | respiratory infections | INTERLEUKIN-17 RECEPTOR | IL-17 RECEPTOR | SEVERE ASTHMA | INFLAMMATION | PROSTATE-CANCER | DOUBLE-BLIND | CYSTIC-FIBROSIS | CHRONIC MUCOCUTANEOUS CANDIDIASIS | CUTTING EDGE | TH17 CELLS | CELL BIOLOGY | Lung - microbiology | Staphylococcal Infections - pathology | Humans | Receptors, Interleukin-17 - immunology | Interleukin-17 - immunology | Hypersensitivity - immunology | Receptors, Interleukin-17 - genetics | Receptors, Interleukin-17 - deficiency | Respiratory Mucosa - pathology | Respiratory Mucosa - microbiology | Aspergillosis - pathology | Hypersensitivity - microbiology | Respiratory Mucosa - immunology | Female | Hypersensitivity - genetics | Protein Isoforms - deficiency | Pseudomonas - immunology | Staphylococcal Infections - microbiology | Disease Models, Animal | Lung - pathology | Staphylococcal Infections - genetics | Aspergillus - immunology | Disease Susceptibility | Signal Transduction | Staphylococcal Infections - immunology | Mice, Inbred C57BL | Aspergillosis - genetics | Gene Expression Regulation | Interleukin-17 - genetics | Epithelial Cells - pathology | Interleukin-17 - deficiency | Pseudomonas Infections - microbiology | Mice, Knockout | Pseudomonas Infections - genetics | Pseudomonas Infections - immunology | Animals | Hypersensitivity - pathology | Epithelial Cells - immunology | Epithelial Cells - microbiology | Aspergillosis - microbiology | Pseudomonas Infections - pathology | Staphylococcus aureus - immunology | Mice | Protein Isoforms - immunology | Lung - immunology | Aspergillosis - immunology | Protein Isoforms - genetics | Index Medicus
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2014, Volume 192, Issue 7, pp. 3289 - 3300
Intrahepatic cell-derived, early IL-17 is important for activating APCs in viral infection; however, the source and regulation of this IL-17 surge in the liver... 
INDUCED HEPATITIS | LIVER-INJURY | INTERLEUKIN-17 | IMMUNE-RESPONSES | INFLAMMATION | IN-VIVO | MICE | INDUCTION | IMMUNOLOGY | LYMPHOCYTIC CHORIOMENINGITIS VIRUS | TH17 CELLS | Liver - virology | Lymphocytic choriomeningitis virus - immunology | Tumor Necrosis Factor-alpha - metabolism | Receptors, Interleukin-17 - immunology | Tumor Necrosis Factor-alpha - genetics | Interleukin-17 - immunology | Virus Diseases - virology | Receptors, Interleukin-17 - genetics | Interferon-gamma - metabolism | Host-Pathogen Interactions - immunology | Liver - immunology | Flow Cytometry | Lymphocytes - immunology | T-Lymphocytes - metabolism | Chemokine CXCL10 - immunology | Tumor Necrosis Factor-alpha - immunology | Female | Lymphocytes - classification | Lymphocytic choriomeningitis virus - physiology | Interferon-gamma - genetics | Receptors, Interleukin-17 - metabolism | Adenoviridae - immunology | Lymphocytes - metabolism | Virus Diseases - immunology | Receptors, Antigen, T-Cell, gamma-delta - metabolism | Liver - metabolism | Mice, Inbred C57BL | Cells, Cultured | Interleukin-17 - genetics | Adenoviridae - physiology | Receptors, Antigen, T-Cell, gamma-delta - immunology | Chemokine CXCL9 - immunology | Reverse Transcriptase Polymerase Chain Reaction | Chemokine CXCL9 - genetics | Mice, Knockout | Interleukin-17 - metabolism | Animals | Chemokine CXCL10 - genetics | Chemokine CXCL9 - metabolism | Interferon-gamma - immunology | T-Lymphocytes - immunology | Mice | Chemokine CXCL10 - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
Circulation, ISSN 0009-7322, 03/2009, Volume 119, Issue 10, pp. 1424 - 1432
Background - Atherosclerosis is an inflammatory disease in which interferon (IFN)-gamma, the signature cytokine of Th1 cells, plays a central role. We... 
Smooth | Inflammation | Muscle | Interleukins | Lymphocytes | Coronary disease | CYTOKINES | CARDIAC & CARDIOVASCULAR SYSTEMS | lymphocytes | muscle, smooth | AUTOIMMUNE INFLAMMATION | HELPER-CELLS | ATHEROSCLEROSIS | IL-23 | interleukins | coronary disease | GROWTH-FACTOR-BETA | inflammation | DISEASE | IL-17 | PERIPHERAL VASCULAR DISEASE | DIFFERENTIATION | HEMATOLOGY | EXPRESSION | Vasculitis - physiopathology | Humans | Middle Aged | Receptors, Interleukin-17 - immunology | Vasculitis - etiology | Interleukin-17 - physiology | Myocytes, Smooth Muscle - pathology | Male | Chemokine CXCL10 - biosynthesis | Coronary Artery Disease - pathology | Inflammation Mediators - metabolism | Interferon-gamma - antagonists & inhibitors | Adult | Female | Interleukin-8 - secretion | Interleukins - pharmacology | Receptors, Interferon - antagonists & inhibitors | Myocytes, Smooth Muscle - metabolism | Transforming Growth Factor beta1 - pharmacology | Cells, Cultured - drug effects | Coronary Vessels - drug effects | Interleukin-17 - secretion | Interleukin-8 - biosynthesis | Interferon-gamma - secretion | Interferon-gamma - physiology | Receptors, Interleukin-17 - antagonists & inhibitors | Interleukin-17 - biosynthesis | Interleukin-6 - secretion | Cells, Cultured - secretion | Gene Expression Regulation - drug effects | Muscle, Smooth, Vascular - pathology | CD4-Positive T-Lymphocytes - secretion | Receptors, Interferon - immunology | Signal Transduction - drug effects | Coronary Artery Disease - complications | Chemokine CXCL10 - secretion | Interleukin-6 - biosynthesis | Aged | Coronary Artery Disease - immunology | T-Lymphocyte Subsets - secretion | Interferon-gamma - biosynthesis | Index Medicus | Abridged Index Medicus | muscle | smooth
Journal Article
Journal of Immunology, ISSN 0022-1767, 11/2007, Volume 179, Issue 10, pp. 7128 - 7136
Journal Article
Journal Article