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1. Full Text IL-2 administration increases CD4(+)CD25(hi) Foxp3(+) regulatory T cells in cancer patients
by Ahmadzadeh, M and Rosenberg, ST
Blood, ISSN 0006-4971, 03/2006, Volume 107, Issue 6, pp. 2409 - 2414
Life Sciences & Biomedicine | Hematology | Science & Technology | Humans | Middle Aged | Kidney Neoplasms - immunology | Male | Forkhead Transcription Factors - drug effects | Forkhead Transcription Factors - genetics | T-Lymphocytes, Regulatory - drug effects | Interleukin-2 - administration & dosage | Melanoma - immunology | Melanoma - drug therapy | Adolescent | Forkhead Transcription Factors - analysis | Interleukin-2 - pharmacology | Lymphocyte Count | Adult | Female | Kidney Neoplasms - drug therapy | Index Medicus | Abridged Index Medicus
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2. Full Text A pilot trial of humanized anti-GD2 monoclonal antibody (hu14.18K322A) with chemotherapy and natural killer cells in children with recurrent/refractory neuroblastoma
by Federico, Sara M and McCarville, M. Beth and Shulkin, Barry L and Sondel, Paul M and Hank, Jacquelyn A and Hutson, Paul and Meagher, Michael and Shafer, Aaron and Ng, Catherine Y and Leung, Wing and Janssen, William E and Wu, Jianrong and Mao, Shenghua and Brennan, Rachel C and Santana, Victor M and Pappo, Alberto S and Furman, Wayne L
Clinical cancer research, ISSN 1078-0432, 11/2017, Volume 23, Issue 21, pp. 6441 - 6449
Life Sciences & Biomedicine | Oncology | Science & Technology | Drug-Related Side Effects and Adverse Reactions - blood | Cyclophosphamide - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Humans | Neuroblastoma - blood | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Child, Preschool | Neoplasm Recurrence, Local - drug therapy | Infant | Male | Drug-Related Side Effects and Adverse Reactions - pathology | Neoplasm Recurrence, Local - pathology | Antibodies, Monoclonal, Humanized - administration & dosage | Antibodies, Monoclonal, Humanized - pharmacokinetics | Dacarbazine - analogs & derivatives | Killer Cells, Natural - immunology | Camptothecin - administration & dosage | Female | Child | Neoplasm Recurrence, Local - blood | Neuroblastoma - pathology | Camptothecin - analogs & derivatives | Antibodies, Monoclonal, Humanized - adverse effects | Dacarbazine - administration & dosage | Gangliosides - antagonists & inhibitors | Interleukin-2 Receptor alpha Subunit - blood | Carboplatin - administration & dosage | Etoposide - administration & dosage | Treatment Outcome | Combined Modality Therapy | Cell- and Tissue-Based Therapy | Gangliosides - immunology | Disease-Free Survival | Ifosfamide - administration & dosage | Neuroblastoma - drug therapy | Adolescent | Topotecan - administration & dosage | Drug-Related Side Effects and Adverse Reactions - classification | Interleukin-2 - blood | Toxicity | Cytotoxicity | Malignancy | Neuroblastoma | Cerebrospinal fluid | Pain | Interleukin 2 | Surgery | Myelosuppression | Children | Natural killer cells | Antibody-dependent cell-mediated cytotoxicity | Thrombocytopenia | Immune response | Cytokines | Ifosfamide | Granulocyte-macrophage colony-stimulating factor | Hypersensitivity | Etoposide | Pharmacology | Patients | Irinotecan | Cyclophosphamide | Chemotherapy | Experimental design | Monoclonal antibodies | Carboplatin | Temozolomide | Pharmacokinetics | Cancer | Index Medicus
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3. Full Text Route of administration modulates the induction of dendritic cell vaccine-induced antigen-specific T cells in advanced melanoma patients
by Lesterhuis, W. Joost and de Vries, I. Jolanda M and Schreibelt, Gerty and Lambeck, Annechien J. A and Aarntzen, Erik H. J. G and Jacobs, Joannes F. M and Scharenborg, Nicole M and van de Rakt, Mandy W. M. M and de Boer, Annemiek J and Croockewit, Sana and van Rossum, Michelle M and Mus, Roel and Oyen, Wim J. G and Boerman, Otto C and Lucas, Sophie and Adema, Gosse J and Punt, Cornelis J. A and Figdor, Carl G
Clinical cancer research, ISSN 1078-0432, 2011, Volume 17, Issue 17, pp. 5725 - 5735
Life Sciences & Biomedicine | Oncology | Science & Technology | Tumors of the skin and soft tissue. Premalignant lesions | Biological and medical sciences | Medical sciences | Antineoplastic agents | Dermatology | Pharmacology. Drug treatments | Lymph Nodes - pathology | Dendritic Cells - immunology | Humans | Middle Aged | Male | Cancer Vaccines - therapeutic use | Interleukin-2 - immunology | Interleukin-2 - administration & dosage | Immunotherapy | Adult | Female | Hemocyanins - immunology | Injections, Intradermal | Drug Administration Routes | Forkhead Transcription Factors - biosynthesis | HLA-A2 Antigen - immunology | Antigens, Neoplasm - immunology | Cancer Vaccines - administration & dosage | Neoplasm Recurrence, Local | Treatment Outcome | Lymph Nodes - immunology | Cancer Vaccines - immunology | B-Lymphocytes - immunology | Melanoma - immunology | T-Lymphocytes - immunology | Aged | Melanoma - therapy | Index Medicus
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4. Full Text Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein
by Bachanova, Veronika and Cooley, Sarah and Defor, Todd E and Verneris, Michael R and Zhang, Bin and McKenna, David H and Curtsinger, Julie and Panoskaltsis-Mortari, Angela and Lewis, Dixie and Hippen, Keli and McGlave, Philip and Weisdorf, Daniel J and Blazar, Bruce R and Miller, Jeffrey S
Blood, ISSN 0006-4971, 06/2014, Volume 123, Issue 25, pp. 3855 - 3863
Life Sciences & Biomedicine | Hematology | Science & Technology | Diphtheria Toxin - administration & dosage | Recombinant Fusion Proteins - immunology | Cyclophosphamide - administration & dosage | Cell Proliferation | Coculture Techniques | Humans | Middle Aged | Recombinant Fusion Proteins - therapeutic use | Interleukin-2 - therapeutic use | Child, Preschool | Male | T-Lymphocytes, Regulatory - immunology | Leukemia, Myeloid - pathology | Young Adult | Diphtheria Toxin - therapeutic use | Interleukin-2 - immunology | Interleukin-2 - administration & dosage | T-Lymphocytes, Regulatory - cytology | Killer Cells, Natural - immunology | Adult | Female | Child | Recombinant Fusion Proteins - administration & dosage | Killer Cells, Natural - transplantation | Acute Disease | Treatment Outcome | Combined Modality Therapy | Vidarabine - analogs & derivatives | Diphtheria Toxin - immunology | Antineoplastic Combined Chemotherapy Protocols - immunology | Remission Induction | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adolescent | K562 Cells | Aged | Vidarabine - administration & dosage | Leukemia, Myeloid - therapy | Lymphocyte Depletion - methods | Index Medicus | Abridged Index Medicus | 33 | 8 | 12 | 2 | Plenary Paper | 29
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5. Full Text Safety and immunologic effects of IL-15 administration in nonhuman primates
by Berger, S. Carolina and Berger, Michael and Hackman, Robert C and Gough, Michael and Elliott, Carole and Jensen, Michael C and Riddell, Stanley R
Blood, ISSN 0006-4971, 2009, Volume 114, Issue 12, pp. 2417 - 2426
Life Sciences & Biomedicine | Hematology | Science & Technology | Hematologic and hematopoietic diseases | Biological and medical sciences | Medical sciences | Interleukin-2 - metabolism | T-Lymphocyte Subsets - immunology | Interleukin-15 - administration & dosage | Macaca nemestrina | Enzyme-Linked Immunosorbent Assay | Glycosylation | T-Lymphocytes, Regulatory - immunology | Animals | Flow Cytometry | CD8-Positive T-Lymphocytes - metabolism | Killer Cells, Natural - immunology | CD8-Positive T-Lymphocytes - immunology | Genes, T-Cell Receptor | Immunologic Memory - immunology | Apoptosis | Index Medicus | Abridged Index Medicus | Immunobiology
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6. Full Text Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy
by Sharma, Meenu and Hiep Khong and Fa'ak, Faisal and Bentebibel, Salah-Eddine and Janssen, Louise M. E and Chesson, Brent C and Creasy, Caitlin A and Forget, Marie-Andree and Kahn, Laura Maria S and Pazdrak, Barbara and Karki, Binisha and Hailemichael, Yared and Singh, Manisha and Vianden, Christina and Vennam, Srinivas and Bharadwaj, Uddalak and Tweardy, David J and Haymaker, Cara and Bernatchez, Chantale and Huang, Shixia and Rajapakshe, Kimal and Coarfa, Cristian and Hurwitz, Michael E and Sznol, Mario and Hwu, Patrick and Hoch, Ute and Addepalli, Murali and Charych, Deborah H and Zalevsky, Jonathan and Diab, Adi and Overwijk, Willem W
Nature communications, ISSN 2041-1723, 01/2020, Volume 11, Issue 1, pp. 661 - 661
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Prodrugs - administration & dosage | Humans | Tumor Necrosis Factor-alpha - genetics | Carcinoma, Renal Cell - genetics | Carcinoma, Renal Cell - immunology | T-Lymphocytes, Regulatory - immunology | Receptors, Interleukin-2 - genetics | Interleukin-2 - agonists | Antibodies, Monoclonal, Humanized - administration & dosage | Interleukin-2 - immunology | Interleukin-2 - administration & dosage | Melanoma - genetics | Tumor Necrosis Factor-alpha - immunology | Female | Interferon-gamma - genetics | Interleukin-2 - analogs & derivatives | Carcinoma, Renal Cell - drug therapy | Drug Therapy, Combination | Ipilimumab - administration & dosage | Mice, Inbred C57BL | Receptors, Interleukin-2 - immunology | Polyethylene Glycols - administration & dosage | Animals | Lymphocyte Activation - drug effects | Melanoma - immunology | Interferon-gamma - immunology | Melanoma - drug therapy | Mice | CD8-Positive T-Lymphocytes - immunology | Cohort Studies | Therapy | Peptides | PD-1 protein | Toxicity | CD8 antigen | Interleukin | Vaccination | Lymphocytes T | Metastases | Anticancer properties | CTLA-4 protein | Antitumor agents | Interleukin 2 | Lymphocytes | CD122 antigen | Interleukin 2 receptors | Cytokines | Immunoregulation | Melanoma | Tumor necrosis factor-α | Depletion | Immune checkpoint | γ-Interferon | Clear cell-type renal cell carcinoma | Cancer | Tumors | Index Medicus
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7. Full Text Induction of tolerance to factor VIII by transient co‐administration with rapamycin
by MOGHIMI, B and SACK, B. K and NAYAK, S and MARKUSIC, D. M and MAH, C. S and HERZOG, R. W
Journal of thrombosis and haemostasis, ISSN 1538-7933, 08/2011, Volume 9, Issue 8, pp. 1524 - 1533
hemophilia | inhibitor | factor VIII | T helper cell | tolerance | rapamycin | Tolerance | Inhibitor | Rapamycin | Factor VIII | Hemophilia | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Factor VIII - immunology | Humans | Transforming Growth Factor beta1 - metabolism | Male | Adoptive Transfer | CD4-Positive T-Lymphocytes - immunology | Time Factors | Forkhead Transcription Factors - metabolism | Coagulants - administration & dosage | Interleukin-6 - metabolism | Immunosuppressive Agents - administration & dosage | Disease Models, Animal | Immune Tolerance - drug effects | Interleukin-2 - metabolism | Drug Administration Schedule | Hemophilia A - immunology | Interleukin-4 - metabolism | Mice, Inbred C57BL | Cells, Cultured | CTLA-4 Antigen - metabolism | Hemophilia A - blood | Recombinant Proteins - administration & dosage | Sirolimus - administration & dosage | Animals | CD4-Positive T-Lymphocytes - transplantation | Interleukin-2 Receptor alpha Subunit - metabolism | Factor VIII - administration & dosage | Antibodies - blood | Mice | Mice, Inbred BALB C | Coagulants - immunology | Hemophilia A - drug therapy | CD4-Positive T-Lymphocytes - drug effects | Blood coagulation factor VIII | T cells | Transforming growth factors | Index Medicus
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8. Full Text Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor α) monoclonal antibody
by Onizuka, Shozaburo and Tawara, Isao and Shimizu, Jun and Sakaguchi, Shimon and Fujita, Teizo and Nakayama, Eiichi
Cancer research (Chicago, Ill.), ISSN 0008-5472, 07/1999, Volume 59, Issue 13, pp. 3128 - 3133
Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Medical sciences | Antineoplastic agents | Immunotherapy | Pharmacology. Drug treatments | Leukemia, Radiation-Induced - therapy | Mice, Inbred A | Fibrosarcoma - therapy | Antibodies, Monoclonal - therapeutic use | Fibrosarcoma - immunology | Male | Multiple Myeloma - immunology | Fibrosarcoma - chemically induced | Lymph Nodes - immunology | Lymphocyte Depletion | Receptors, Interleukin-2 - immunology | CD4-Positive T-Lymphocytes - immunology | Leukemia, Experimental - immunology | Multiple Myeloma - therapy | Animals | Flow Cytometry | Leukemia, Experimental - therapy | Lymphocytes - immunology | Mice, Nude | Leukemia, Radiation-Induced - immunology | Female | Mice | Mice, Inbred BALB C | CD8-Positive T-Lymphocytes - immunology | Index Medicus | AIDS/HIV
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9. Full Text In vivo targeting of adoptively transferred T-cells with antibody- and cytokine-conjugated liposomes
by Zheng, Yiran and Stephan, Matthias T and Gai, S. Annie and Abraham, Wuhbet and Shearer, Adrianne and Irvine, Darrell J
Journal of controlled release, ISSN 0168-3659, 12/2013, Volume 172, Issue 2, pp. 426 - 435
Immunoliposomes | Cancer immunotherapy | Adoptive cell therapy | Targeted delivery | Interleukin-2 (IL-2) | Melanoma | Pharmacology & Pharmacy | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Cell Proliferation | Liposomes - administration & dosage | Humans | Immunoconjugates - administration & dosage | T-Lymphocytes - transplantation | Cytokines - chemistry | Immunoconjugates - immunology | Interleukin-2 - immunology | Interleukin-2 - administration & dosage | Female | Interleukin-2 - chemistry | Cytokines - immunology | Liposomes - immunology | Immunotherapy, Adoptive - methods | Lymphocyte Activation | Mice, Inbred C57BL | Melanoma - pathology | Cytokines - administration & dosage | Immunoconjugates - chemistry | Melanoma - secondary | Immunoglobulin Fab Fragments - administration & dosage | Liposomes - chemistry | Animals | Melanoma - immunology | Immunoglobulin Fab Fragments - chemistry | T-Lymphocytes - immunology | Mice | Immunoglobulin Fab Fragments - immunology | Melanoma - therapy | Viral antibodies | Chemotherapy | Cytokines | Antibodies | T cells | Cancer | Tumors | Index Medicus | interleukin-2 (IL-2) | targeted delivery | melanoma | immunoliposomes | adoptive cell therapy | cancer immunotherapy
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10. Full Text Interleukin-35 administration counteracts established murine type 1 diabetes - possible involvement of regulatory T cells
by Singh, Kailash and Kadesjö, Erik and Lindroos, Julia and Hjort, Marcus and Lundberg, Marcus and Espes, Daniel and Carlsson, Per-Ola and Sandler, Stellan and Thorvaldson, Lina
Scientific reports, ISSN 2045-2322, 07/2015, Volume 5, Issue 1, pp. 12633 - 12633
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Leukocytes, Mononuclear - metabolism | T-Lymphocytes, Regulatory - metabolism | Minor Histocompatibility Antigens | Humans | Diabetes Mellitus, Type 1 - metabolism | Interleukin-10 - blood | Male | Recombinant Proteins - biosynthesis | Interleukins - metabolism | T-Lymphocytes, Regulatory - immunology | Recombinant Proteins - isolation & purification | Interleukins - genetics | Diabetes Mellitus, Experimental - prevention & control | Flow Cytometry | Forkhead Transcription Factors - metabolism | T-Lymphocytes, Helper-Inducer - immunology | T-Lymphocytes, Helper-Inducer - cytology | T-Lymphocytes, Regulatory - cytology | Diabetes Mellitus, Experimental - chemically induced | Receptors, Cytokine - metabolism | Thymus Gland - metabolism | Disease Models, Animal | Interleukin-2 - metabolism | Hyperglycemia - prevention & control | T-Lymphocytes, Helper-Inducer - metabolism | Cytokines - metabolism | Enzyme-Linked Immunosorbent Assay | Interleukins - blood | Diabetes Mellitus, Type 1 - pathology | Transforming Growth Factor beta - blood | Recombinant Proteins - administration & dosage | Diabetes Mellitus, Experimental - immunology | Phenotype | Animals | Interleukins - administration & dosage | Spleen - metabolism | Diabetes Mellitus, Type 1 - blood | Leukocytes, Mononuclear - cytology | Mice, Inbred NOD | Mice | Streptozocin - toxicity | Immunoregulation | Streptozocin | Diabetes mellitus | T cell receptors | Lymphocytes T | Inflammation | Interleukin 17 | Hyperglycemia | Interleukin 2 | Rodents | Interleukin 10 | Interferon | Diabetes | Autoimmune diseases | Index Medicus
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