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Journal Article
Journal Article
Journal Article
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 2016, Volume 44, Issue 4, pp. 875 - 888
Journal Article
Nature communications, ISSN 2041-1723, 2011, Volume 2, Issue 1, p. 240
The immune system can both promote and suppress cancer. Chronic inflammation and proinflammatory cytokines such as interleukin (IL)-1 and IL-6 are considered... 
LUNG-CANCER | INTERFERON-INDUCIBLE PROTEIN-10 | NECROSIS IN-VIVO | PROGNOSTIC-FACTORS | INTERLEUKIN-1 RECEPTOR ANTAGONIST | IFN-GAMMA | MULTIDISCIPLINARY SCIENCES | CD4(+) T-CELLS | ADJUVANT THERAPY | CARCINOMA | EXPRESSION | Angiostatic Proteins - immunology | Immunohistochemistry | Neoplasms - metabolism | Interleukin-1alpha - immunology | Chemokine CXCL9 - biosynthesis | Tumor Microenvironment | Multiple Myeloma - immunology | Th2 Cells - immunology | Th1 Cells - immunology | CD4-Positive T-Lymphocytes - immunology | Chemokine CXCL10 - biosynthesis | Inflammation - metabolism | Interleukin-2 - immunology | Chemokine CXCL10 - immunology | Lymphoma, B-Cell - immunology | Interleukin-1beta - biosynthesis | Macrophages - immunology | Interleukin-12 - biosynthesis | Lymphoma, B-Cell - metabolism | Signal Transduction | Angiostatic Proteins - biosynthesis | CD4-Positive T-Lymphocytes - cytology | CD4-Positive T-Lymphocytes - metabolism | Interleukin-1beta - immunology | Chemokine CXCL9 - immunology | Inflammation - immunology | Macrophages - cytology | Mice, SCID | Multiple Myeloma - metabolism | Macrophages - metabolism | Multiple Myeloma - pathology | Animals | Neoplasms - immunology | Interferon-gamma - immunology | Interleukin-12 - immunology | Interleukin-6 - immunology | Lymphoma, B-Cell - pathology | Cell Line, Tumor | Interleukin-6 - biosynthesis | Interleukin-1alpha - biosynthesis | Mice | Interleukin-2 - biosynthesis | Neoplasms - pathology | Interferon-gamma - biosynthesis
Journal Article
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 07/2014, Volume 41, Issue 1, pp. 127 - 140
Memory CD8+ T cells are programmed during the primary response for robust secondary responsiveness. Here we show that CD8+ T cells responding to different... 
IMMUNODOMINANCE | EFFECTOR | RESPONSES | VIRUS-INFECTION | DENDRITIC CELLS | CD8-T-CELL MEMORY | CD4-T-CELL HELP | CD40 LIGAND | IMMUNOLOGY | VIRAL-INFECTION | CROSS-PRESENTATION | Antigens, CD - immunology | CD40 Antigens - antagonists & inhibitors | Minor Histocompatibility Antigens | Dendritic Cells - immunology | Interleukin-2 Receptor alpha Subunit - biosynthesis | Adoptive Transfer | Signal Transduction - immunology | Lymphocyte Activation - immunology | Interleukin-2 - immunology | Interleukin-2 Receptor alpha Subunit - genetics | Integrin alpha Chains - immunology | Influenza A virus - immunology | CD40 Antigens - genetics | Histocompatibility Antigens Class I - pharmacology | Epitopes, T-Lymphocyte - immunology | Immunologic Memory - immunology | Nucleoproteins - immunology | Tumor Necrosis Factor Receptor Superfamily, Member 7 - immunology | CD11b Antigen - immunology | CD27 Ligand - biosynthesis | Mice, Inbred C57BL | Cells, Cultured | DNA-Directed RNA Polymerases - immunology | Mice, Transgenic | Antigen Presentation - immunology | Animals | Viral Core Proteins - immunology | Mice | CD8-Positive T-Lymphocytes - immunology | CD40 Antigens - immunology | Interferon-gamma - biosynthesis | Orthomyxoviridae Infections - immunology | Flow cytometry | Antigens | Lymphocytes | Ligands | T cell receptors | Infections | Experiments | Immune system
Journal Article
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 2009, Volume 30, Issue 6, pp. 832 - 844
Effector T cell differentiation requires the simultaneous integration of multiple, and sometimes opposing, cytokine signals. We demonstrated mTOR's role in... 
MOLIMMUNO | CELLIMMUNO | MAMMALIAN TARGET | RAPAMYCIN | FOXP3 EXPRESSION | MAINTENANCE | ACTIVATION | PATHWAY | AKT | INDUCTION | IMMUNOLOGY | TH17 | INSIGHTS | Phosphotransferases (Alcohol Group Acceptor) - immunology | STAT Transcription Factors - metabolism | STAT Transcription Factors - immunology | T-Lymphocytes, Regulatory - immunology | Signal Transduction - immunology | Interleukin-2 - immunology | T-Lymphocytes, Helper-Inducer - immunology | T-Lymphocytes, Helper-Inducer - enzymology | Receptors, Antigen, T-Cell - immunology | Transcription Factors - immunology | Carrier Proteins - immunology | Trans-Activators - immunology | Transforming Growth Factor beta - immunology | Receptors, Antigen, T-Cell - metabolism | Phosphotransferases (Alcohol Group Acceptor) - genetics | Transcription Factors - genetics | Mice, Knockout | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Transcription Factors - metabolism | Carrier Proteins - genetics | Cell Differentiation - immunology | Animals | Carrier Proteins - metabolism | Trans-Activators - metabolism | Mice | TOR Serine-Threonine Kinases | Interleukin-2 - biosynthesis | Transforming Growth Factor beta - metabolism | T-Lymphocytes, Regulatory - enzymology | Genetic research | DNA binding proteins | Transforming growth factors | T cells | Proteins | Cell growth | Phosphorylation | T cell receptors | Kinases | Rodents
Journal Article