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International immunology, ISSN 1460-2377, 2007, Volume 19, Issue 4, pp. 345 - 354
Forkhead box P3 (FOXP3) is currently thought to be the most specific marker for naturally occurring CD4+CD25+ T regulatory cells (nTregs). In mice, expression... 
INTERLEUKIN-2 | TGF-BETA | T cell activation | transcription factors | INDUCTION | IMMUNOLOGY | T cells | REGULATORY-CELLS | TRANSCRIPTION FACTOR FOXP3 | COSTIMULATION | GENERATION | FLOW-CYTOMETRY | DIFFERENTIATION | human | EXPRESSION | tolerance | T-Lymphocyte Subsets - immunology | Cysteine - analogs & derivatives | T-Lymphocytes, Regulatory - metabolism | Cell Proliferation | Coculture Techniques | Humans | Clonal Anergy | Receptors, Nerve Growth Factor - metabolism | Interferon-gamma - metabolism | Antigens, CD - metabolism | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Flagellin - pharmacology | Lymphocyte Activation - immunology | Forkhead Transcription Factors - metabolism | T-Lymphocyte Subsets - drug effects | Cysteine - pharmacology | Antigens, Differentiation - metabolism | Interleukin-2 - metabolism | Receptors, Tumor Necrosis Factor - metabolism | Cell Line | Cytokines - metabolism | Lectins, C-Type | Toll-Like Receptors - immunology | CD4-Positive T-Lymphocytes - metabolism | Glucocorticoid-Induced TNFR-Related Protein | Antigens, Differentiation, T-Lymphocyte - metabolism | CD28 Antigens - immunology | Antibodies - pharmacology | CTLA-4 Antigen | T-Lymphocytes, Regulatory - drug effects | Interleukin-2 Receptor alpha Subunit - metabolism | Lipoproteins - pharmacology | T-Lymphocyte Subsets - metabolism | Interleukin-7 Receptor alpha Subunit - metabolism | CD3 Complex - immunology | Interleukin-2 - pharmacology | CD4-Positive T-Lymphocytes - drug effects
Journal Article
The Journal of experimental medicine, ISSN 0022-1007, 2012, Volume 209, Issue 13, pp. 2441 - 2453
.... However, PI3K-Akt-independent mechanisms control glucose metabolism in CD8(+) T cells, and the role of mTORC1 has not been... 
MAMMALIAN TARGET | RAPAMYCIN | SURVIVAL | MEDICINE, RESEARCH & EXPERIMENTAL | EFFECTOR FUNCTIONS | L-SELECTIN | ACTIVATION | KINASE | RECEPTOR | DIFFERENTIATION | IMMUNOLOGY | LYMPHOCYTES | CD8-Positive T-Lymphocytes - cytology | TOR Serine-Threonine Kinases - metabolism | Multiprotein Complexes | Phosphatidylinositol 3-Kinases - metabolism | Aryl Hydrocarbon Receptor Nuclear Translocator - metabolism | Hypoxia-Inducible Factor 1 - metabolism | Cell Movement - physiology | Hypoxia-Inducible Factor 1 - genetics | Mechanistic Target of Rapamycin Complex 1 | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Mice, Mutant Strains | CD8-Positive T-Lymphocytes - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Cell Differentiation - physiology | 3-Phosphoinositide-Dependent Protein Kinases | Protein-Serine-Threonine Kinases - metabolism | Receptors, Antigen, T-Cell - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Mice, Inbred C57BL | Receptors, Chemokine - metabolism | Gene Expression Regulation | Protein-Serine-Threonine Kinases - genetics | Mice, Transgenic | Phosphatidylinositol 3-Kinases - genetics | Animals | Proteins - metabolism | Glucose - metabolism | Glycolysis | Interleukin-2 - pharmacology | Aryl Hydrocarbon Receptor Nuclear Translocator - genetics | Chemokines - metabolism | Mice | CD8-Positive T-Lymphocytes - immunology
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2009, Volume 106, Issue 32, pp. 13463 - 13468
Journal Article
Gastroenterology, ISSN 0016-5085, 2007, Volume 133, Issue 2, pp. 559 - 573
Background & Aims: Recent studies have revealed that murine intestinal mucosa contains several kinds of lineage markers (lin)– c-kit+ immune precursor cells.... 
Gastroenterology and Hepatology | INFLAMMATORY-BOWEL-DISEASE | GUT CRYPTOPATCHES | NK CELLS | DENDRITIC CELLS | PEYERS-PATCHES | ALPHA-BETA | LYMPH-NODES | DELTA-T-CELLS | GASTROENTEROLOGY & HEPATOLOGY | LYMPHOCYTES-T | FETAL THYMUS | Membrane Glycoproteins - metabolism | Humans | Colitis, Ulcerative - genetics | Crohn Disease - metabolism | Hematopoietic Stem Cells - pathology | Lymphotoxin-alpha - metabolism | Interferon-gamma - metabolism | RNA, Messenger - metabolism | Colitis, Ulcerative - immunology | Antigens, CD - metabolism | Immunoglobulins - metabolism | Lymphotoxin-alpha - genetics | Time Factors | Intestinal Mucosa - immunology | Inhibitor of Differentiation Protein 2 - genetics | Cell Differentiation | Gene Expression | Colitis, Ulcerative - metabolism | Colitis, Ulcerative - pathology | Inhibitor of Differentiation Protein 2 - metabolism | Cell Lineage | Adult Stem Cells - metabolism | Interleukin-2 Receptor alpha Subunit - metabolism | Crohn Disease - pathology | ADP-ribosyl Cyclase 1 - metabolism | Killer Cells, Natural - metabolism | Intestinal Mucosa - pathology | Crohn Disease - genetics | Intestinal Mucosa - metabolism | Antigens, CD34 - metabolism | Killer Cells, Natural - pathology | Proto-Oncogene Proteins c-kit - metabolism | Adult Stem Cells - immunology | DNA-Binding Proteins - metabolism | Hematopoietic Stem Cells - immunology | Trans-Activators - genetics | Killer Cells, Natural - immunology | Adult Stem Cells - pathology | Sialic Acid Binding Ig-like Lectin 3 | Proto-Oncogene Proteins - metabolism | CD56 Antigen - metabolism | Receptors, Interleukin-7 - metabolism | Cells, Cultured | Immunophenotyping | Proto-Oncogene Proteins - genetics | Hematopoietic Stem Cells - metabolism | Integrin alpha Chains - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Crohn Disease - immunology | Transcription Factors - metabolism | Antigens, Differentiation, Myelomonocytic - metabolism | Trans-Activators - metabolism
Journal Article
Kidney international, ISSN 0085-2538, 2013, Volume 83, Issue 6, pp. 1065 - 1075
Collapsing focal segmental glomerulosclerosis (cFSGS) is a progressive kidney disease characterized by glomerular collapse with epithelial hyperplasia. Here we... 
parietal epithelial cell | focal segmental glomerulosclerosis | podocyte loss | Notch signaling | Focal segmental glomerulosclerosis | Parietal epithelial cell | Podocyte loss | KINASE | MOUSE | NOTCH | SCLEROSIS | RATS | MESENCHYMAL TRANSITION | NEPHRON | PATHWAY | DISEASE | UROLOGY & NEPHROLOGY | TGF-BETA/SMAD | Cell Proliferation | RNA, Untranslated - metabolism | Homeodomain Proteins - metabolism | Humans | Hyperplasia | Transforming Growth Factor beta1 - metabolism | Proteinuria - pathology | RNA, Untranslated - genetics | Dibenzazepines - pharmacology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Time Factors | Serrate-Jagged Proteins | Disease Models, Animal | Jagged-1 Protein | Biomarkers - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Membrane Proteins - genetics | Enzyme Inhibitors - pharmacology | Epithelial Cells - pathology | Mice, Transgenic | Kidney Glomerulus - pathology | Podocytes - pathology | Proteinuria - genetics | Amyloid Precursor Protein Secretases - metabolism | Interleukin-2 Receptor alpha Subunit - metabolism | Claudin-1 - genetics | Mice | Receptor, Notch1 - antagonists & inhibitors | Calcium-Binding Proteins - genetics | Cell Movement | Transcription Factor HES-1 | Epithelial Cells - metabolism | Epithelial Cells - drug effects | Glomerulosclerosis, Focal Segmental - genetics | Intercellular Signaling Peptides and Proteins - metabolism | Interleukin-2 Receptor alpha Subunit - genetics | Claudin-1 - metabolism | Kidney Glomerulus - metabolism | Integrases - metabolism | Membrane Proteins - metabolism | Calcium-Binding Proteins - metabolism | Cell Line | Podocytes - metabolism | Kidney Glomerulus - drug effects | Intercellular Signaling Peptides and Proteins - genetics | Proteinuria - metabolism | Antibodies, Monoclonal | Receptor, Notch1 - metabolism | Homeodomain Proteins - genetics | Glomerulosclerosis, Focal Segmental - metabolism | Animals | Exotoxins | Podocytes - drug effects | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Integrases - genetics | Glomerulosclerosis, Focal Segmental - pathology | Apoptosis
Journal Article
STEM CELLS, ISSN 1066-5099, 01/2008, Volume 26, Issue 1, pp. 212 - 222
Adult bone marrow‐derived mesenchymal stem cells (MSCs) are multipotent cells that are the subject of intense investigation in regenerative medicine. In... 
Immunosuppression | Regulatory T cells | Human leukocyte antigen‐G | Mesenchymal stem cells | Interleukin‐10 | Interleukin-10 | Human leukocyte antigen-G | T-Lymphocyte Subsets - immunology | T-Lymphocytes, Regulatory - metabolism | Humans | Adult Stem Cells - immunology | Lymphocyte Culture Test, Mixed | Mesenchymal Stromal Cells - immunology | T-Lymphocytes, Regulatory - immunology | Histocompatibility Antigens Class I - metabolism | Mesenchymal Stromal Cells - cytology | Flow Cytometry | Forkhead Transcription Factors - metabolism | Bone Marrow Cells - immunology | Killer Cells, Natural - immunology | T-Lymphocytes, Cytotoxic - immunology | Interferon-gamma | Adult Stem Cells - cytology | Enzyme-Linked Immunosorbent Assay | Bone Marrow Cells - cytology | Cell Communication | Mesenchymal Stromal Cells - metabolism | HLA-G Antigens | HLA Antigens - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Microscopy, Confocal | Adult Stem Cells - metabolism | Interleukin-2 Receptor alpha Subunit - metabolism | T-Lymphocytes, Cytotoxic - metabolism | T-Lymphocyte Subsets - metabolism | Killer Cells, Natural - metabolism | Bone Marrow Cells - metabolism | CD4 Antigens - metabolism | T-Lymphocyte Subsets | Adult Stem Cells | Interleukin-2 Receptor alpha Subunit | Killer Cells, Natural | Antigens, CD4 | Histocompatibility Antigens Class I | T-Lymphocytes, Cytotoxic | Mesenchymal Stem Cells | Life Sciences | Bone Marrow Cells | Immunology | T-Lymphocytes, Regulatory | HLA Antigens | Forkhead Transcription Factors
Journal Article
Journal of investigative dermatology, ISSN 0022-202X, 2013, Volume 133, Issue 7, pp. 1879 - 1889
Journal Article
Journal Article
Nature immunology, ISSN 1529-2916, 2013, Volume 14, Issue 6, pp. 564 - 573
Type 2 immunity is critical for defense against cutaneous infections but also underlies the development of allergic skin diseases. We report the identification... 
ATOPIC-DERMATITIS | TRANSCRIPTION FACTOR GATA3 | MAST-CELLS | IN-VIVO | TYPE-2 IMMUNITY | MICE | INFLUENZA-VIRUS | IMMUNOLOGY | EXPRESSION | LUNG INFLAMMATION | THYMIC STROMAL LYMPHOPOIETIN | Cell Communication - immunology | Eosinophils - metabolism | Dermatitis - immunology | Skin - metabolism | Homeodomain Proteins - metabolism | Immunity, Innate - genetics | Interleukin-17 - immunology | Interleukin-13 - immunology | Green Fluorescent Proteins - genetics | Homeodomain Proteins - immunology | Eosinophils - immunology | Flow Cytometry | Interleukin-2 - immunology | Lymphocytes - immunology | Mast Cells - metabolism | Dermis - cytology | Microscopy, Fluorescence, Multiphoton | Skin - immunology | Lymphocytes - metabolism | Green Fluorescent Proteins - metabolism | Mast Cells - immunology | Dermis - metabolism | Videotape Recording | Dermatitis - genetics | Mice, Inbred C57BL | Cells, Cultured | Mice, Transgenic | Interleukin-13 - metabolism | Dermis - immunology | Homeodomain Proteins - genetics | Mice, Knockout | Immunity, Innate - immunology | Interleukin-17 - metabolism | Animals | Lymphocytes - drug effects | Interleukin-2 - pharmacology | Mice | Mice, Inbred BALB C | Dermatitis - metabolism | Care and treatment | Development and progression | Inflammation | Genetic aspects | Research | T cells | Health aspects
Journal Article
Circulation Research, ISSN 0009-7330, 05/2016, Volume 118, Issue 10, pp. 1540 - 1552
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, p. e0179431
Cytokines are potent immune modulating agents but are not ideal medicines in their natural form due to their short half-life and pleiotropic systemic effects.... 
LIGAND-BINDING | ALPHA-RECEPTOR | MULTIDISCIPLINARY SCIENCES | LONG-TERM SAFETY | COMPLEXES | REGULATORY T-CELLS | MODULATION THERA