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JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 06/2017, Volume 198, Issue 12, pp. 4563 - 4568
Interleukin 2 and IL-15 are two closely related cytokines, displaying important functions in the immune system. They share the heterodimeric CD122/CD132... 
BETA-CHAIN | INTERLEUKIN-2 | LYMPHOID HOMEOSTASIS | ALPHA-CHAIN | IL-15 | TRANS-PRESENTATION | IL-15R-ALPHA | IMMUNOLOGY | EXPRESSION | T-CELLS | Cell Proliferation | Humans | Interleukin Receptor Common gamma Subunit - metabolism | Interleukin-15 Receptor alpha Subunit - metabolism | Interleukin-2 - antagonists & inhibitors | Interleukin-15 - immunology | Interleukin Receptor Common gamma Subunit - immunology | T-Lymphocytes, Regulatory - immunology | Signal Transduction - immunology | Lymphocyte Activation - immunology | Interleukin-2 - immunology | Interleukin-2 Receptor alpha Subunit - genetics | Killer Cells, Natural - immunology | Interleukin-15 Receptor alpha Subunit - immunology | Interleukin-2 Receptor beta Subunit - genetics | Interleukin-2 Receptor alpha Subunit - immunology | Interleukin-2 - metabolism | Cell Line | Interleukin-15 - antagonists & inhibitors | Interleukin-15 Receptor alpha Subunit - genetics | Interleukin Receptor Common gamma Subunit - genetics | Animals | Interleukin-2 Receptor alpha Subunit - metabolism | Interleukin-15 - metabolism | Protein Binding | Mice | CD8-Positive T-Lymphocytes - immunology | Interleukin-2 Receptor beta Subunit - immunology | Cell proliferation | Interleukin 2 receptors | Cytokines | Interleukin 2 | CD8 antigen | Interleukin | Lymphocytes T | Interleukin 15 | Immune system | Recruitment | CD122 antigen | Index Medicus | Abridged Index Medicus | Life Sciences | Cancer
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 12/2009, Volume 183, Issue 11, pp. 7023 - 7030
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2010, Volume 107, Issue 5, pp. 2171 - 2176
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, pp. e0179431 - e0179431
Cytokines are potent immune modulating agents but are not ideal medicines in their natural form due to their short half-life and pleiotropic systemic effects.... 
LIGAND-BINDING | ALPHA-RECEPTOR | MULTIDISCIPLINARY SCIENCES | LONG-TERM SAFETY | COMPLEXES | REGULATORY T-CELLS | MODULATION THERAPIES | IL-2 | CYTOKINE | HIGH-DOSE INTERLEUKIN-2 | RENAL-CELL CARCINOMA | Neoplasms - metabolism | T-Lymphocytes, Regulatory - metabolism | Immunotherapy - methods | Interleukin-2 Receptor beta Subunit - metabolism | Interleukin Receptor Common gamma Subunit - metabolism | Transplantation, Homologous | T-Lymphocytes, Regulatory - immunology | STAT5 Transcription Factor - metabolism | Neoplasms - therapy | Interleukin Receptor Common gamma Subunit - agonists | CD8-Positive T-Lymphocytes - metabolism | Female | Interleukin-2 - analogs & derivatives | Phosphorylation - drug effects | Polyethylene Glycols - pharmacology | Models, Theoretical | Tumor Microenvironment - drug effects | Interleukin-2 - pharmacokinetics | Interleukin-2 Receptor beta Subunit - agonists | Mice, Inbred C57BL | Polyethylene Glycols - pharmacokinetics | Receptors, Interleukin-2 - metabolism | Mice, Inbred C3H | Tumor Microenvironment - immunology | T-Lymphocytes, Regulatory - drug effects | Algorithms | Animals | Interleukin-2 Receptor alpha Subunit - agonists | Interleukin-2 Receptor alpha Subunit - metabolism | Prodrugs - pharmacokinetics | Neoplasms - immunology | CD8-Positive T-Lymphocytes - drug effects | Cell Line, Tumor | Drug Liberation | Interleukin-2 - pharmacology | Mice, Inbred BALB C | Kinetics | CD8-Positive T-Lymphocytes - immunology | Prodrugs - pharmacology | Receptors, Interleukin-2 - agonists | Physiological aspects | Care and treatment | Interleukin-2 | Immunotherapy | Patient outcomes | Cancer | Polyethylenes | Conjugates | CD8 antigen | Interleukin | Lymphocytes T | Anticancer properties | Proteins | Biological effects | Cell activation | Immunology | Interleukin 2 | Lymphocytes | Polyethylene glycol | Modelling | Drug dosages | Immune system | Interleukin 2 receptors | Pharmacodynamics | Cytokines | Immunoregulation | Melanoma | Radioactive half-life | Pharmacology | Affinity | Ligands | Mutation | Pharmacokinetics | In vitro methods and tests | Tumors | Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 06/2009, Volume 30, Issue 6, pp. 899 - 911
Journal Article
Immunity, ISSN 1074-7613, 05/2012, Volume 36, Issue 5, pp. 847 - 856
T follicular helper (Tfh) cells promote T cell-dependent humoral immune responses by providing T cell help to B cells and by promoting germinal center (GC)... 
B-CELLS | RESPONSES | ACTIVATION | AUTOIMMUNITY | FOLLICLES | IN-VIVO | NON-HODGKINS-LYMPHOMA | MICE | IL-2 | RECOMBINANT INTERLEUKIN-2 | IMMUNOLOGY | T-Lymphocytes, Regulatory - metabolism | Germinal Center - immunology | Orthomyxoviridae - immunology | T-Lymphocytes, Regulatory - immunology | DNA-Binding Proteins - metabolism | Interleukin-2 - immunology | Immunoglobulin G - immunology | T-Lymphocytes, Helper-Inducer - immunology | T-Lymphocytes, Helper-Inducer - cytology | Germinal Center - cytology | B-Lymphocytes - metabolism | Interleukin-2 Receptor alpha Subunit - immunology | Interleukin-2 - metabolism | Antibody Formation - immunology | T-Lymphocytes, Helper-Inducer - metabolism | Orthomyxoviridae Infections - metabolism | Mice, Inbred C57BL | Orthomyxoviridae - metabolism | DNA-Binding Proteins - genetics | Cell Differentiation - immunology | Animals | B-Lymphocytes - immunology | Germinal Center - metabolism | Interleukin-2 Receptor alpha Subunit - metabolism | Mice | Orthomyxoviridae Infections - immunology | Immunoglobulin G - metabolism | Proto-Oncogene Proteins c-bcl-6 | Immunoglobulins | Interleukins | T cells | Immunoglobulin G | Bone marrow | Antigens | Autoimmune diseases | Rodents | Immune system | Index Medicus | Molecular modelling | Germinal centers | Interleukin 2 | Lymphocytes B | Helper cells | Data processing | Lymphocytes T | Differentiation | Immune response (humoral)
Journal Article
International Immunology, ISSN 0953-8178, 4/2007, Volume 19, Issue 4, pp. 345 - 354
Forkhead box P3 (FOXP3) is currently thought to be the most specific marker for naturally occurring CD4+CD25+ T regulatory cells (nTregs). In mice, expression... 
INTERLEUKIN-2 | TGF-BETA | T cell activation | transcription factors | INDUCTION | IMMUNOLOGY | T cells | REGULATORY-CELLS | TRANSCRIPTION FACTOR FOXP3 | COSTIMULATION | GENERATION | FLOW-CYTOMETRY | DIFFERENTIATION | human | EXPRESSION | tolerance | T-Lymphocyte Subsets - immunology | Cysteine - analogs & derivatives | T-Lymphocytes, Regulatory - metabolism | Cell Proliferation | Coculture Techniques | Humans | Clonal Anergy | Receptors, Nerve Growth Factor - metabolism | Interferon-gamma - metabolism | Antigens, CD - metabolism | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Flagellin - pharmacology | Lymphocyte Activation - immunology | Forkhead Transcription Factors - metabolism | T-Lymphocyte Subsets - drug effects | Cysteine - pharmacology | Antigens, Differentiation - metabolism | Interleukin-2 - metabolism | Receptors, Tumor Necrosis Factor - metabolism | Cell Line | Cytokines - metabolism | Lectins, C-Type | Toll-Like Receptors - immunology | CD4-Positive T-Lymphocytes - metabolism | Glucocorticoid-Induced TNFR-Related Protein | Antigens, Differentiation, T-Lymphocyte - metabolism | CD28 Antigens - immunology | Antibodies - pharmacology | CTLA-4 Antigen | T-Lymphocytes, Regulatory - drug effects | Interleukin-2 Receptor alpha Subunit - metabolism | Lipoproteins - pharmacology | T-Lymphocyte Subsets - metabolism | Interleukin-7 Receptor alpha Subunit - metabolism | CD3 Complex - immunology | Interleukin-2 - pharmacology | CD4-Positive T-Lymphocytes - drug effects | Index Medicus
Journal Article
Journal Article