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Journal of Experimental Medicine, ISSN 0022-1007, 11/2013, Volume 210, Issue 12, pp. 2739 - 2753
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, p. e57820
Pathology studies of progressive multiple sclerosis (MS) indicate a major role of inflammation including Th17-cells and meningeal inflammation with ectopic... 
DENDRITIC CELLS | MESSENGER-RNA | CD86 B7-2 | MULTIDISCIPLINARY SCIENCES | CHEMOKINE RECEPTOR | MENINGEAL INFLAMMATION | ADHESION MOLECULES | EXPRESSION | AUTOIMMUNE ENCEPHALOMYELITIS | LESIONS | CORTICAL PATHOLOGY | Inflammation - pathology | Cell Adhesion Molecules - genetics | Humans | Interleukins - cerebrospinal fluid | Middle Aged | Dendritic Cells - pathology | Male | Monocytes - metabolism | Lectins, C-Type - genetics | Interleukin-23 - genetics | Receptors, Interleukin - metabolism | Interleukins - genetics | Flow Cytometry | Interleukin-23 - cerebrospinal fluid | Th17 Cells - metabolism | Inducible T-Cell Co-Stimulator Protein - genetics | Monocytes - pathology | Adult | Female | B-Lymphocytes - pathology | B-Lymphocytes - metabolism | Dendritic Cells - metabolism | Multiple Sclerosis, Chronic Progressive - genetics | Th17 Cells - pathology | Multiple Sclerosis, Chronic Progressive - cerebrospinal fluid | Gene Expression | Lymphocyte Activation | Inflammation - cerebrospinal fluid | Cell Adhesion Molecules - cerebrospinal fluid | Multiple Sclerosis, Chronic Progressive - pathology | Receptors, Interleukin - genetics | Disease Progression | Interleukin-21 Receptor alpha Subunit - metabolism | Inflammation - genetics | Inducible T-Cell Co-Stimulator Protein - metabolism | Interleukin-21 Receptor alpha Subunit - genetics | Receptors, Cell Surface - genetics | Complications and side effects | Multiple sclerosis | Prognosis | Physiological aspects | Development and progression | Inflammation | Genetic aspects | Research | B cells | Flow cytometry | Neurosciences | Disease | CD8 antigen | Interleukin | Helper cells | Fluid flow | Interleukin 23 | Lymphocytes T | Cerebrospinal fluid | Follicles | Blood | Rodents | Peripheral blood | Interleukin 21 | Age | Cytokines | Dendritic cells | Blood cells | T cell receptors | Gene expression | Patients | CD4 antigen | DC-SIGN protein | Studies | CD83 antigen | Pathology | Neurology | Cytometry | Monocytes | Gene flow | Lymphocytes B | Correlation analysis | ICOS protein | Plasma cells
Journal Article
Arthritis Research and Therapy, ISSN 1478-6354, 11/2012, Volume 14, Issue 6, pp. R255 - R255
Introduction: Interleukin (IL)-21 is a member of type I cytokine family. Recent studies indicate that IL-21 can promote T follicular helper (Tfh) cell... 
IMMUNE-RESPONSES | RECEPTOR | ANTIBODY | GENERATION | CYTOKINE | MICE | INTERLEUKIN-21 | DIFFERENTIATION | RHEUMATOLOGY | DISEASE-ACTIVITY | CUTTING EDGE | Antigens, CD - immunology | Leukocytes, Mononuclear - metabolism | Apoptosis - drug effects | Arthritis, Rheumatoid - blood | Humans | Middle Aged | Lectins, C-Type - immunology | Male | Adrenal Cortex Hormones - therapeutic use | Antigens, CD - metabolism | T-Lymphocytes, Helper-Inducer - drug effects | Lectins, C-Type - metabolism | Flow Cytometry | Arthritis, Rheumatoid - drug therapy | T-Lymphocytes, Helper-Inducer - immunology | Interleukins - immunology | Leukocytes, Mononuclear - immunology | Female | Interleukins - pharmacology | Drug Therapy, Combination | B-Lymphocytes - metabolism | Antirheumatic Agents - therapeutic use | Interleukin-2 Receptor alpha Subunit - immunology | Severity of Illness Index | Leukocytes, Mononuclear - drug effects | T-Lymphocytes, Helper-Inducer - metabolism | Antigens, Differentiation, T-Lymphocyte - immunology | Interleukins - blood | Receptors, Interleukin-21 - immunology | Cells, Cultured | Antigens, Differentiation, T-Lymphocyte - metabolism | Receptors, Interleukin-21 - metabolism | B-Lymphocytes - drug effects | Cell Differentiation - immunology | Autoantibodies - immunology | Apoptosis - immunology | B-Lymphocytes - immunology | Interleukin-2 Receptor alpha Subunit - metabolism | Cell Differentiation - drug effects | Cell Proliferation - drug effects | Arthritis, Rheumatoid - immunology | Autoantibodies | Interleukin-21 | Analysis | Immunoglobulin G | Rheumatoid arthritis | Arthritis | Cellular signal transduction | B cells | T cells | Cell differentiation | Immunity | Enzyme-linked immunosorbent assay
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 01/2009, Volume 206, Issue 1, pp. 69 - 78
Journal Article
Journal Article
Blood, ISSN 0006-4971, 07/2011, Volume 118, Issue 2, pp. 446 - 455
Journal Article
Journal Article
European Journal of Immunology, ISSN 0014-2980, 08/2011, Volume 41, Issue 8, pp. 2248 - 2259
CD4(+) T cells are implied to sustain CD8(+) T-cell responses during persistent infections. As CD4(+) T cells are often themselves antiviral effectors, they... 
Latent infection | CD4 | T-cell inflation | Memory CD8 | T cells | Mouse CMV | SECONDARY EXPANSION | CD8-T-CELL MEMORY | CD4-T-CELL HELP | PERSISTENCE | IMMUNOLOGY | CHRONIC VIRAL-INFECTION | Memory CD8(+) T-cell inflation | EFFECTOR | RESPONSES | MICE | CD4(+) T cells | LYMPHOCYTES | Receptors, Interleukin-21 - genetics | Cytomegalovirus Infections - immunology | Adoptive Transfer | CD4-Positive T-Lymphocytes - immunology | Flow Cytometry | Interleukin-2 Receptor alpha Subunit - genetics | CD8-Positive T-Lymphocytes - metabolism | Cytomegalovirus Infections - virology | Histocompatibility Antigens Class II - metabolism | Immunologic Memory - immunology | CD4 Antigens - genetics | Interleukin-2 Receptor alpha Subunit - immunology | CD4 Antigens - immunology | Receptors, Interleukin-21 - immunology | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Receptors, Interleukin-21 - metabolism | Virus Replication - immunology | Mice, Knockout | Muromegalovirus - immunology | Antigens, Viral - immunology | Animals | Histocompatibility Antigens Class II - immunology | Interleukin-2 Receptor alpha Subunit - metabolism | Muromegalovirus - physiology | Fluorescent Antibody Technique | Mice | Histocompatibility Antigens Class II - genetics | CD8-Positive T-Lymphocytes - immunology | Virus Latency - immunology | CD4 Antigens - metabolism | Cytomegalovirus | T cell receptors | Infections | Lymphocytes | Human immunodeficiency virus--HIV | Immune system
Journal Article
Immunology, ISSN 0019-2805, 11/2017, Volume 152, Issue 3, pp. 507 - 516
Interleukin 27 ( IL ‐27) has been identified as a potent cytokine in the differentiation of type 1 regulatory T (Tr1) cells through interactions with several... 
interleukin‐21 receptor | interleukin‐27 | phosphoinositide 3‐kinase | type 1 regulatory T cells | interleukin-27 | interleukin-21 receptor | phosphoinositide 3-kinase | FOXP3 EXPRESSION | ACTIVATION | IMMUNE CELLS | DENDRITIC CELLS | TRANSCRIPTION | RECEPTOR | AKT | INDUCTION | IMMUNOLOGY | C-MAF | TR1 CELLS | T-Lymphocytes, Regulatory - metabolism | Phosphorylation | Phosphatidylinositol 3-Kinase - antagonists & inhibitors | Interleukin-21 Receptor alpha Subunit - immunology | Proto-Oncogene Proteins c-akt - genetics | T-Lymphocytes, Regulatory - immunology | Forkhead Box Protein O1 - immunology | Forkhead Transcription Factors - metabolism | Interleukin-10 - metabolism | Female | Proto-Oncogene Proteins c-akt - metabolism | Phosphatidylinositol 3-Kinase - metabolism | Interleukin-27 - pharmacology | Forkhead Box Protein O1 - metabolism | Mice, Inbred C57BL | Cells, Cultured | Genotype | Mice, Transgenic | Forkhead Transcription Factors - genetics | Interleukin-21 Receptor alpha Subunit - metabolism | Phenotype | T-Lymphocytes, Regulatory - drug effects | Animals | Signal Transduction - drug effects | Cell Differentiation - drug effects | Interleukin-10 - genetics | Mice, Inbred BALB C | Protein Kinase Inhibitors - pharmacology | Interleukins | T cells | Cell differentiation | Transcription factors | Cytokines | Immunoregulation | Interleukin | Differentiation (biology) | AKT protein | Lymphocytes T | Interleukin 27 | 1-Phosphatidylinositol 3-kinase | Receptors | Aromatic compounds | Lymphocytes | Interleukin 21 | Interleukin 10 | Autocrine signalling | Original
Journal Article
Journal Article