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1. Full Text Highly Effective New Treatments for Psoriasis Target the IL-23 Type 17 T Cell Autoimmune Axis
by Kim, Jaehwan and Krueger, James G
Annual review of medicine, ISSN 0066-4219, 1/2017, Volume 68, Issue 1, pp. 255 - 269
IL-17 antagonists | TNF antagonists | psoriasis vulgaris | biologic drugs | IL-23 antagonists | cytokines | polar T cell subsets | pathogenesis of psoriasis | Polar T cell subsets | Psoriasis vulgaris | Cytokines | Pathogenesis of psoriasis | Biologic drugs | Psoriasis - immunology | Interleukin-23 Subunit p19 - antagonists & inhibitors | Psoriasis - drug therapy | Dendritic Cells - immunology | Humans | HLA Antigens - immunology | Dermatologic Agents - therapeutic use | Interleukin-12 Subunit p40 - antagonists & inhibitors | Th17 Cells - drug effects | Interleukin-17 - antagonists & inhibitors | Interleukin-23 - antagonists & inhibitors | Th17 Cells - immunology | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Psoriasis | Interleukins | Physiological aspects | Genetic aspects | Research | T cells | Drug therapy | Index Medicus
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2. Full Text The Expanding Therapeutic Armamentarium for Inflammatory Bowel Disease: How to Choose the Right Drug[s] for Our Patients?
by Hinyckx, Pieter and Vande Casteele, Niels and Novak, Gregor and Khanna, Reena and D'Haens, Geert and Sandborn, William J and Danese, Silvio and Jairath, Vipul and Feagan, Brian G
Journal of Crohn's and colitis, ISSN 1873-9946, 2018, Volume 12, Issue 1, pp. 105 - 119
Inflammatory bowel disease | Therapy | TNF antagonists | Sphingosine-1 phosphate | IL-23 antagonists | JAK inhibitors | Smad7 | Pipeline | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Antibodies, Monoclonal, Humanized - adverse effects | Immunoglobulins | Antibodies, Monoclonal, Humanized - therapeutic use | Smad7 Protein - antagonists & inhibitors | Humans | Immunosuppressive Agents - therapeutic use | Protein Kinase Inhibitors - adverse effects | Adrenal Cortex Hormones - therapeutic use | Molecular Targeted Therapy | Janus Kinases - antagonists & inhibitors | Algorithms | Interleukin-23 - antagonists & inhibitors | Protein Kinase Inhibitors - therapeutic use | Crohn Disease - drug therapy | Interleukin-12 - antagonists & inhibitors | Vascular Cell Adhesion Molecule-1 - antagonists & inhibitors | Colitis, Ulcerative - drug therapy | Drug Therapy, Combination | Mucoproteins - antagonists & inhibitors | Integrins - antagonists & inhibitors | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Index Medicus
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3. Full Text Predictors of drug survival for tumour necrosis factor‐α and interleukin 12/23 antagonists in psoriasis
by Egeberg, A
British journal of dermatology (1951), ISSN 0007-0963, 08/2016, Volume 175, Issue 2, pp. 247 - 248
Life Sciences & Biomedicine | Dermatology | Science & Technology | Psoriasis | Humans | Interleukin-12 | Interleukin-23 | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Interleukin-6 | Index Medicus
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4. Full Text Small-Molecule RORγt Antagonists: One Stone Kills Two Birds
by Zhong, Chao and Zhu, Jinfang
Trends in immunology, ISSN 1471-4906, 2017, Volume 38, Issue 4, pp. 229 - 231
Allergy and Immunology | Life Sciences & Biomedicine | Immunology | Science & Technology | Autoimmunity | Interleukin-17 - metabolism | Nuclear Receptor Subfamily 1, Group F, Member 3 - antagonists & inhibitors | Animals | Interleukin-23 - metabolism | Autoantigens - immunology | Humans | Th17 Cells - immunology | Mice | Thymocytes - immunology | Substance abuse treatment | Cytokines | CD8 antigen | Interleukin | Helper cells | T cell receptors | Lymphocytes T | Inflammation | Gene expression | Thymus | CD4 antigen | Thymocytes | Lymphocytes | Rodents | Ligands | Autoimmune diseases | Retinoic acid | Apoptosis | Index Medicus
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5. Full Text Anticytokine Immune Therapy and Atherothrombotic Cardiovascular Risk
by Ait-Oufella, Hafid and Libby, Peter and Tedgui, Alain
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 08/2019, Volume 39, Issue 8, pp. 1510 - 1519
Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Animals | Interleukin-6 - antagonists & inhibitors | Interleukin-17 - antagonists & inhibitors | Interleukin-23 - antagonists & inhibitors | Cardiovascular Diseases - prevention & control | Humans | Cytokines - antagonists & inhibitors | Thrombosis - prevention & control | Atherosclerosis - prevention & control | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Interleukin-1beta - antagonists & inhibitors | Index Medicus
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6. Full Text The Society for Immunotherapy of Cancer perspective on regulation of interleukin-6 signaling in COVID-19-related systemic inflammatory response
by Arnaldez, Fernanda I and O'Day, Steven J and Drake, Charles G and Fox, Bernard A and Fu, Bingqing and Urba, Walter J and Montesarchio, Vincenzo and Weber, Jeffrey S and Wei, Haiming and Wigginton, Jon M and Ascierto, Paolo Antonio
Journal for immunotherapy of cancer, ISSN 2051-1426, 5/2020, Volume 8, Issue 1, p. e000930
Oncology | Immunology | Life Sciences & Biomedicine | Science & Technology | Inflammation - pathology | Interleukin-6 - antagonists & inhibitors | Pandemics | Coronavirus Infections - drug therapy | Humans | Pneumonia, Viral - drug therapy | Antibodies, Monoclonal - therapeutic use | Respiratory Distress Syndrome - immunology | Adoptive Transfer | COVID-19 | Inflammation - complications | Neoplasms - therapy | Respiratory Distress Syndrome - complications | Societies, Medical | Inflammation - drug therapy | Interleukin-23 - antagonists & inhibitors | Antibodies, Monoclonal, Humanized - pharmacology | Immunotherapy | Pneumonia, Viral - complications | Interferon-gamma - antagonists & inhibitors | Coronavirus Infections - complications | Respiratory Distress Syndrome - drug therapy | Cytokine Release Syndrome - drug therapy | Interleukin-1 - antagonists & inhibitors | Interleukin-6 - metabolism | Cytokine Release Syndrome - immunology | Antibodies, Monoclonal, Humanized - therapeutic use | Interleukin-6 - genetics | Antibodies, Monoclonal - pharmacology | Pneumonia, Viral - pathology | Cytokine Release Syndrome - complications | Inflammation - immunology | Coronavirus Infections - immunology | Pneumonia, Viral - immunology | Janus Kinases - antagonists & inhibitors | Respiratory Distress Syndrome - pathology | Interleukin-17 - antagonists & inhibitors | Signal Transduction - drug effects | Neoplasms - immunology | Cytokine Release Syndrome - pathology | Coronavirus Infections - pathology | Interleukin-6 - immunology | Granulocyte-Macrophage Colony-Stimulating Factor - antagonists & inhibitors | STAT Transcription Factors - antagonists & inhibitors | Severe Acute Respiratory Syndrome - pathology | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Index Medicus
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7. Full Text Expert opinion on interleukin-12/23 and interleukin-23 antagonists as potential therapeutic options for the treatment of inflammatory bowel disease
by Wong, Uni and Cross, Raymond K
Expert opinion on investigational drugs, ISSN 1354-3784, 05/2019, Volume 28, Issue 5, pp. 473 - 479
interleukin-12/23 | ustekinumab | risankizumab | Crohn's disease | ulcerative colitis | brazikumab | guselkumab | inflammatory bowel disease | interleukin-12 | interleukin-23 | mirizumab | Crohn’s disease | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Gastrointestinal Agents - pharmacology | Animals | Interleukin-23 - antagonists & inhibitors | Crohn Disease - drug therapy | Humans | Interleukin-12 - antagonists & inhibitors | Ustekinumab - pharmacology | Crohn Disease - physiopathology | Gastrointestinal Agents - adverse effects | Colitis, Ulcerative - drug therapy | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Colitis, Ulcerative - physiopathology | Index Medicus
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8. Full Text Human interleukin‐23 receptor antagonists derived from an albumin‐binding domain scaffold inhibit IL‐23‐dependent ex vivo expansion of IL‐17‐producing T‐cells
by Kuchař, Milan and Vaňková, Lucie and Petroková, Hana and Černý, Jiří and Osička, Radim and Pelák, Ondřej and Šípová, Hana and Schneider, Bohdan and Homola, Jiří and Šebo, Peter and Kalina, Tomáš and Malý, Petr
Proteins, structure, function, and bioinformatics, ISSN 0887-3585, 06/2014, Volume 82, Issue 6, pp. 975 - 989
cytokine | protein scaffold | ribosome display | engineered binding protein | psoriasis | combinatorial library | Protein scaffold | Psoriasis | Engineered binding protein | Combinatorial library | Cytokine | Ribosome display | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Binding, Competitive | Amino Acid Sequence | Immunologic Factors - chemistry | Receptors, Interleukin - physiology | Anti-Inflammatory Agents - pharmacology | Jurkat Cells | Humans | Bacterial Proteins - chemistry | Molecular Sequence Data | Peptide Fragments - pharmacology | Receptors, Interleukin - antagonists & inhibitors | Sequence Homology, Amino Acid | Peptide Fragments - chemistry | Th17 Cells - drug effects | Anti-Inflammatory Agents - chemistry | Th17 Cells - metabolism | K562 Cells | Interleukin-23 - chemistry | Protein Binding | Drug Evaluation, Preclinical | Interleukin-23 - physiology | Immunologic Factors - pharmacology | Interleukins | Leukemia | Albumin | Chemical properties | T cells | Binding proteins | Protein binding | Index Medicus
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