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Cell Stem Cell, ISSN 1934-5909, 07/2009, Volume 5, Issue 1, pp. 31 - 42
Journal Article
Molecular Therapy, ISSN 1525-0016, 08/2017, Volume 25, Issue 8, pp. 1933 - 1945
Chimeric antigen receptor (CAR)-redirected T lymphocytes are a promising immunotherapeutic approach and object of pre-clinical evaluation for the treatment of... 
AML | CAR | CD123 | immunotherapy | affinity | MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | DOMAIN | T-CELL-RECEPTORS | RECOGNITION | COMPLEXES | INDUCTION | ANTITUMOR-ACTIVITY | THRESHOLD | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | IN-VIVO | GENETICS & HEREDITY | LYMPHOCYTES | Receptors, Antigen, T-Cell - chemistry | Gene Expression | Immunotherapy, Adoptive | Receptors, Antigen, T-Cell - metabolism | Immunomodulation | Humans | Leukemia, Myeloid, Acute - metabolism | Molecular Conformation | Models, Molecular | Structure-Activity Relationship | Leukemia, Myeloid, Acute - immunology | Recombinant Fusion Proteins | Interleukin-3 Receptor alpha Subunit - chemistry | T-Lymphocytes - metabolism | Interleukin-3 Receptor alpha Subunit - immunology | Protein Binding | T-Lymphocytes - immunology | Receptors, Antigen, T-Cell - genetics | Interleukin-3 Receptor alpha Subunit - metabolism | Binding Sites | Leukemia, Myeloid, Acute - therapy | Cytotoxicity, Immunologic | Interleukin-3 Receptor alpha Subunit - antagonists & inhibitors | Leukemia, Myeloid, Acute - genetics | Antigens | Cytokines | Hematology | Myeloid leukemia | Therapeutic applications | Leukemia | Cytotoxicity | Lymphocytes T | Grants | Experiments | Design | Lymphocytes | Computer applications | Stem cells | Conflicts of interest | Receptor density | CD123 antigen | Affinity | Software | Acute myeloid leukemia | Binding sites | Index Medicus | Original
Journal Article
British Journal of Haematology, ISSN 0007-1048, 05/2013, Volume 161, Issue 3, pp. 389 - 401
Current therapeutic regimens for acute myeloid leukaemia ( AML ) are still associated with high rates of relapse. Immunotherapy with T ‐cells genetically... 
AML | 123 | cells | CIK | acute myeloid leukaemia | CAR | chimeric antigen receptor | leukaemia stem cell | LSC | cytokine‐induced killer | Leukaemia stem cell (LSC) | Chimeric antigen receptor (CAR) | Acute myeloid leukaemia (AML) | Cytokine-induced killer (CIK) cells | IL3RA (CD123) | acute myeloid leukaemia (AML) | INTERLEUKIN-3 RECEPTOR | chimeric antigen receptor (CAR) | STEM-CELLS | cytokine-induced killer (CIK) cells | ACUTE MYELOGENOUS LEUKEMIA | leukaemia stem cell (LSC) | SUICIDE GENE-THERAPY | ANTIBODY-LIKE IMMUNORECEPTORS | SIGNAL-TRANSDUCTION | ALPHA-CHAIN | HEMATOLOGY | PHASE-I | T-CELLS | ADOPTIVE IMMUNOTHERAPY | Human Umbilical Vein Endothelial Cells | Tumor Stem Cell Assay | Cytotoxicity Tests, Immunologic | Immunotherapy, Adoptive - methods | Endothelial Cells | Transduction, Genetic | Leukemia, Monocytic, Acute - pathology | Leukemia, Myeloid, Acute - pathology | Coculture Techniques | Humans | Cytokines - secretion | Recombinant Fusion Proteins - physiology | Male | Cytokine-Induced Killer Cells - immunology | Monocytes | Leukemia, Myelomonocytic, Acute - pathology | HEK293 Cells | Female | Receptors, Cell Surface - physiology | Cell Line, Tumor - secretion | Hematopoietic Stem Cells | Interleukin-3 Receptor alpha Subunit - antagonists & inhibitors | Antigens | Killer cells | Cytokines | Immunotherapy | Stem cells | Genetically modified organisms | T cells | Health aspects | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 04/2017, Volume 129, Issue 17, pp. 2395 - 2407
We and others previously reported potent antileukemia efficacy of CD123-redirected chimeric antigen receptor (CAR) T cells in preclinical human acute myeloid... 
MULTIPLE-MYELOMA | GEMTUZUMAB OZOGAMICIN | THERAPY | B-CELL | SAFETY | ACUTE LYMPHOBLASTIC-LEUKEMIA | INTERNATIONAL EXPERT PANEL | IN-VIVO | HEMATOLOGY | SUICIDE-GENE | GROUP TRIAL AAML0531 | Recombinant Fusion Proteins - immunology | RNA, Messenger - immunology | Humans | Male | Transplantation, Heterologous | Tumor Necrosis Factor Receptor Superfamily, Member 9 - genetics | Leukemia, Myeloid, Acute - immunology | Lymphocyte Depletion | T-Lymphocytes - transplantation | Lentivirus - metabolism | CD3 Complex - genetics | T-Lymphocytes - drug effects | Antibodies, Monoclonal, Humanized - pharmacology | Female | Lentivirus - genetics | Receptors, Antigen, T-Cell - immunology | Leukemia, Myeloid, Acute - therapy | Antigens, CD20 - immunology | Gene Expression | Immunotherapy, Adoptive - methods | Genetic Vectors - chemistry | Leukemia, Myeloid, Acute - pathology | RNA, Messenger - genetics | Tumor Necrosis Factor Receptor Superfamily, Member 9 - immunology | Genetic Vectors - metabolism | Hematopoietic Stem Cell Transplantation | RNA, Antisense - immunology | Treatment Outcome | Alemtuzumab | Remission Induction | Antigens, CD20 - genetics | Rituximab - pharmacology | Xenograft Model Antitumor Assays | Animals | T-Lymphocytes - cytology | Interleukin-3 Receptor alpha Subunit - genetics | Interleukin-3 Receptor alpha Subunit - immunology | CD3 Complex - immunology | Recombinant Fusion Proteins - genetics | Mice, Inbred NOD | T-Lymphocytes - immunology | Mice | Receptors, Antigen, T-Cell - genetics | Interleukin-3 Receptor alpha Subunit - antagonists & inhibitors | Leukemia, Myeloid, Acute - genetics | RNA, Antisense - genetics | Index Medicus | Abridged Index Medicus | Immunobiology
Journal Article
Leukemia & Lymphoma, ISSN 1042-8194, 05/2015, Volume 56, Issue 5, pp. 1406 - 1415
Journal Article
Journal of Immunology, ISSN 0022-1767, 11/2006, Volume 177, Issue 9, pp. 5829 - 5839
Journal Article
Haematologica, ISSN 0390-6078, 2015, Volume 100, Issue 2, pp. 223 - 230
Journal Article
Haematologica, ISSN 0390-6078, 07/2015, Volume 100, Issue 7, pp. 914 - 926
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 07/2017, Volume 23, Issue 13, pp. 3385 - 3395
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 04/2017, Volume 18, Issue 4, p. 716
Journal Article