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Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 130, Issue 2, pp. 516 - 522.e4
Journal Article
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 05/2010, Volume 184, Issue 9, pp. 4827 - 4841
This article shows that T cell activation-induced expression of the cytokines IL-2 and -4 is determined by an oxidative signal originating from mitochondrial... 
INTERLEUKIN-2 | HUMAN-LYMPHOCYTES | COMPLEX-I | REDOX REGULATION | TRANSCRIPTION | GENE-EXPRESSION | RESPIRATORY INHIBITORS | HYDROGEN-PEROXIDE | DOPAMINERGIC-NEURONS | IMMUNOLOGY | ROTENONE INHIBITION | DNA, Mitochondrial - antagonists & inhibitors | Mitochondria - enzymology | NADH Dehydrogenase - antagonists & inhibitors | Dermatitis, Atopic - genetics | Reactive Oxygen Species - metabolism | T-Lymphocytes - enzymology | Dermatitis, Atopic - enzymology | Electron Transport Complex I - deficiency | Humans | NADH Dehydrogenase - genetics | Th2 Cells - immunology | Interleukin-2 - antagonists & inhibitors | Receptors, Antigen, T-Cell - antagonists & inhibitors | Th2 Cells - drug effects | Receptors, Antigen, T-Cell - biosynthesis | Lymphocyte Activation - immunology | DNA, Mitochondrial - genetics | Time Factors | Electron Transport Complex I - genetics | T-Lymphocytes - drug effects | Dermatitis, Atopic - immunology | Interleukin-4 - genetics | Immunosuppressive Agents - pharmacology | Electron Transport Complex I - antagonists & inhibitors | Interleukin-4 - antagonists & inhibitors | Gene Expression Regulation - immunology | Jurkat Cells | RNA, Small Interfering - pharmacology | Cells, Cultured | Ciprofloxacin - pharmacology | Immunophenotyping | Mitochondria - metabolism | Mitochondria - drug effects | Gene Expression Regulation - drug effects | Interleukin-2 - genetics | Interleukin-4 - secretion | Reactive Oxygen Species - antagonists & inhibitors | Lymphocyte Activation - drug effects | T-Lymphocytes - immunology | Receptors, Antigen, T-Cell - genetics | Interleukin-2 - secretion | Th2 Cells - enzymology
Journal Article
The Journal of Immunology, ISSN 0022-1767, 11/2009, Volume 183, Issue 10, pp. 6681 - 6688
The alpha 7 nicotinic acetylcholine receptor (nAChR) was recently described as an anti-inflammatory target in both macrophages and T cells. Its expression by... 
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | INFLAMMATORY-BOWEL-DISEASE | IMMUNE-SYSTEM | MULTIPLE-SCLEROSIS | EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS | ROR-GAMMA | ACTIVE ULCERATIVE-COLITIS | TRANSDERMAL NICOTINE | IMMUNOLOGY | T-CELLS | ACETYLCHOLINE-RECEPTOR | GATA3 Transcription Factor - agonists | T-Box Domain Proteins - antagonists & inhibitors | Encephalomyelitis, Autoimmune, Experimental - immunology | NF-kappa B - metabolism | Interferon-gamma - metabolism | Interleukin-4 - agonists | RNA, Messenger - metabolism | Interleukins - metabolism | CD4-Positive T-Lymphocytes - immunology | Peptide Fragments - immunology | Tumor Necrosis Factor-alpha - immunology | GATA3 Transcription Factor - metabolism | Th1 Cells - drug effects | Antigen-Presenting Cells - metabolism | NF-kappa B - antagonists & inhibitors | Antigen-Presenting Cells - drug effects | Myelin-Oligodendrocyte Glycoprotein | T-Box Domain Proteins - metabolism | Interleukins - antagonists & inhibitors | Mice, Knockout | Spinal Cord - immunology | Interleukin-4 - immunology | Receptors, Nicotinic - immunology | Glycoproteins - immunology | Mice | alpha7 Nicotinic Acetylcholine Receptor | Tumor Necrosis Factor-alpha - metabolism | RNA, Messenger - immunology | Spinal Cord - drug effects | Encephalomyelitis, Autoimmune, Experimental - metabolism | GATA3 Transcription Factor - immunology | Interleukin-17 - immunology | NF-kappa B - immunology | T-Box Domain Proteins - immunology | Th1 Cells - immunology | Nicotine - pharmacology | Spinal Cord - pathology | Interleukins - immunology | Interferon-gamma - antagonists & inhibitors | Female | RNA, Messenger - drug effects | Receptors, Nicotinic - drug effects | Interleukin-4 - metabolism | Mice, Inbred C57BL | Antigen-Presenting Cells - immunology | Animals | Interleukin-17 - antagonists & inhibitors | Interferon-gamma - immunology | Cell Proliferation - drug effects | Receptors, Nicotinic - genetics | CD4-Positive T-Lymphocytes - drug effects | Tumor Necrosis Factor-alpha - antagonists & inhibitors
Journal Article
Science Translational Medicine, ISSN 1946-6234, 05/2016, Volume 8, Issue 337, pp. 337ra65 - 337ra65
Journal Article
Immunity, ISSN 1074-7613, 02/2016, Volume 44, Issue 2, pp. 246 - 258
Journal Article
Expert Opinion on Biological Therapy, ISSN 1471-2598, 02/2014, Volume 14, Issue 2, pp. 165 - 181
Journal Article
Thorax, ISSN 0040-6376, 01/2013, Volume 68, Issue 1, pp. 9 - 18
Background Current pharmacotherapy is highly effective in the clinical management of the majority of patients with stable asthma, however severe asthma remains... 
FIBROSIS | OVEREXPRESSION | RESPIRATORY SYSTEM | INFLAMMATION | MOUSE MODEL | DISEASE | REGULATORY T-CELLS | STELLATE CELLS | INTERLEUKIN-13 | HYPERRESPONSIVENESS | ALLERGEN CHALLENGE | Immunohistochemistry | Follistatin - immunology | Ovalbumin - immunology | Cytokines - analysis | Activins - antagonists & inhibitors | Bronchoalveolar Lavage Fluid - immunology | Reference Values | Airway Remodeling - immunology | Ovalbumin - metabolism | Interleukin-5 - analysis | Transforming Growth Factor beta - analysis | Interleukin-13 - analysis | Sensitivity and Specificity | Asthma - immunology | Female | Bronchoalveolar Lavage Fluid - cytology | Disease Models, Animal | Cytokines - metabolism | Enzyme-Linked Immunosorbent Assay | Interleukin-5 - metabolism | Interleukin-4 - metabolism | Random Allocation | Interleukin-13 - metabolism | Interleukin-4 - analysis | Administration, Intranasal | Asthma - drug therapy | Animals | Analysis of Variance | Follistatin - pharmacology | Mice | Mice, Inbred BALB C | Airway Remodeling - drug effects | Asthma - pathology | Transforming Growth Factor beta - metabolism | Drugs | Dose-response relationship (Biochemistry) | Antiasthmatic agents | Dosage and administration | Product/Service Evaluations | Drug therapy | Asthma | Studies | Medical research | Immunology | Cytokines | Rodents | Smooth muscle | Inflammation | Growth factors | Allergies | Biological activity
Journal Article
Allergy, ISSN 0105-4538, 01/2010, Volume 65, Issue 1, pp. 69 - 77
Journal Article