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The Journal of Immunology, ISSN 0022-1767, 11/2009, Volume 183, Issue 10, pp. 6469 - 6477
Alternatively activated macrophages (AAM) play a crucial role in type 2 immunity. Mice deficient in ST2, a receptor for the latest member of the IL-1 family,... 
IL-1-LIKE CYTOKINE IL-33 | IMMUNE-RESPONSE | ST2 RECEPTOR | EFFECTOR FUNCTION | MAST-CELLS | IN-VIVO | INDUCED ARTHRITIS | ALVEOLAR MACROPHAGES | INTERLEUKIN-1 RECEPTOR | IMMUNOLOGY | T-CELLS | Interleukin-1 Receptor-Like 1 Protein | Asthma - metabolism | Epithelial Cells - metabolism | Ovalbumin - immunology | Humans | Middle Aged | Chemokine CCL24 - metabolism | Interleukin-13 - immunology | Male | Interleukins - metabolism | Receptors, Interleukin - metabolism | Signal Transduction - immunology | Inflammation - metabolism | Interleukins - immunology | Asthma - immunology | Chemokine CCL17 - immunology | Adult | Female | Interleukin-4 - genetics | Macrophages, Alveolar - immunology | Recombinant Proteins - metabolism | Cell Polarity - immunology | Lung - pathology | Receptors, Interleukin - immunology | Interleukin-33 | Macrophage Activation - immunology | Receptors, Interleukin-1 - immunology | Interleukin-4 - metabolism | Receptors, Interleukin-4 - metabolism | Inflammation - immunology | Receptors, Interleukin-4 - immunology | Interleukin-13 - metabolism | Chemokine CCL24 - immunology | Receptors, Interleukin - genetics | Mice, Knockout | Receptors, Interleukin-1 - metabolism | Interleukin-4 - immunology | Animals | Eosinophilia - immunology | Recombinant Proteins - immunology | Epithelial Cells - immunology | Receptors, Interleukin-4 - genetics | Mice | Mice, Inbred BALB C | Macrophages, Alveolar - metabolism | Chemokine CCL17 - metabolism | Lung - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 06/2010, Volume 70, Issue 11, pp. 4335 - 4345
Journal Article
Nature Immunology, ISSN 1529-2908, 08/2014, Volume 15, Issue 10, pp. 938 - 946
We examined the role of innate cells in acquired resistance to the natural murine parasitic nematode, Nippostrongylus brasiliensis. Macrophages obtained from... 
ADAPTIVE IMMUNITY | ALTERNATIVELY ACTIVATED MACROPHAGES | PROTECTIVE IMMUNITY | INTESTINAL NEMATODE PARASITES | LARVAL STRONGYLOIDES-STERCORALIS | INNATE | INFECTION | IMMUNOLOGY | NIPPOSTRONGYLUS-BRASILIENSIS | T-CELLS | HOST PROTECTION | Oligonucleotide Array Sequence Analysis | Strongylida Infections - genetics | Interleukin-13 - immunology | Disease Resistance - immunology | Transcriptome - immunology | Nippostrongylus - immunology | Interleukin-4 Receptor alpha Subunit - genetics | Interleukin-13 - genetics | Flow Cytometry | Larva - immunology | Strongylida Infections - parasitology | Strongylida Infections - immunology | Female | Lung - metabolism | Adaptive Immunity - immunology | Cytokines - genetics | Neutrophils - metabolism | Macrophages - immunology | Cytokines - immunology | Interleukin-4 Receptor alpha Subunit - metabolism | Cytokines - metabolism | Lung - parasitology | Cells, Cultured | Neutrophils - immunology | Host-Parasite Interactions - immunology | Interleukin-13 - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Interleukin-4 Receptor alpha Subunit - immunology | Mice, Knockout | Cell Adhesion - immunology | Macrophages - metabolism | Animals | Nippostrongylus - physiology | Cell Adhesion - physiology | Mice, Inbred BALB C | Larva - physiology | Lung - immunology | Host-parasite relationships | Genetic aspects | Immune response | Properties | Macrophages | Neutrophils | Index Medicus | Parasite | macrophage | type 2 response | helminth | neutrophil | TH2 cytokines
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 131, Issue 1, pp. 187 - 200.e8
Journal Article
NATURE, ISSN 0028-0836, 07/2011, Volume 475, Issue 7354, pp. 110 - U133
High-dose intravenous immunoglobulin is a widely used therapeutic preparation of highly purified immunoglobulin G (IgG) antibodies. It is administered at high... 
IMMUNITY IN-VIVO | ALLERGIC INFLAMMATION | RESPONSES | ANTIINFLAMMATORY ACTIVITY | DC-SIGN | DENDRITIC CELL | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | TYPE-2 IMMUNITY | AUTOIMMUNE-DISEASE | FC | Cell Adhesion Molecules - genetics | Dendritic Cells - immunology | Humans | Lectins, C-Type - immunology | Th2 Cells - immunology | Cell Adhesion Molecules - immunology | Lectins, C-Type - genetics | Th2 Cells - drug effects | Interleukins - metabolism | Receptors, IgG - metabolism | Immunoglobulins, Intravenous - metabolism | Lectins, C-Type - metabolism | Immunoglobulin G - immunology | Inflammation - drug therapy | Interleukins - immunology | Basophils - immunology | Arthritis - immunology | Immunoglobulin G - pharmacology | Interleukins - pharmacology | Bone Marrow | Autoimmune Diseases - drug therapy | Macrophages - immunology | Basophils - drug effects | Arthritis - pathology | Interleukin-33 | Immunoglobulin G - chemistry | Interleukin-4 - metabolism | Autoimmune Diseases - immunology | Crystallization | Receptors, Cell Surface - metabolism | Inflammation - immunology | Macrophages - cytology | Receptors, IgG - immunology | Cell Adhesion Molecules - metabolism | Immunoglobulins, Intravenous - pharmacology | Receptors, Cell Surface - immunology | Interleukin-4 - immunology | Animals | Arthritis - drug therapy | Ligands | Dendritic Cells - cytology | Immunoglobulins, Intravenous - chemistry | Mice | Basophils - metabolism | Immunoglobulins, Intravenous - immunology | Immunoglobulin G - metabolism | Receptors, Cell Surface - genetics | Index Medicus
Journal Article
The Journal of Immunology, ISSN 0022-1767, 11/2009, Volume 183, Issue 10, pp. 6681 - 6688
The alpha 7 nicotinic acetylcholine receptor (nAChR) was recently described as an anti-inflammatory target in both macrophages and T cells. Its expression by... 
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | INFLAMMATORY-BOWEL-DISEASE | IMMUNE-SYSTEM | MULTIPLE-SCLEROSIS | EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS | ROR-GAMMA | ACTIVE ULCERATIVE-COLITIS | TRANSDERMAL NICOTINE | IMMUNOLOGY | T-CELLS | ACETYLCHOLINE-RECEPTOR | GATA3 Transcription Factor - agonists | T-Box Domain Proteins - antagonists & inhibitors | Encephalomyelitis, Autoimmune, Experimental - immunology | NF-kappa B - metabolism | Interferon-gamma - metabolism | Interleukin-4 - agonists | RNA, Messenger - metabolism | Interleukins - metabolism | CD4-Positive T-Lymphocytes - immunology | Peptide Fragments - immunology | Tumor Necrosis Factor-alpha - immunology | GATA3 Transcription Factor - metabolism | Th1 Cells - drug effects | Antigen-Presenting Cells - metabolism | NF-kappa B - antagonists & inhibitors | Antigen-Presenting Cells - drug effects | Myelin-Oligodendrocyte Glycoprotein | T-Box Domain Proteins - metabolism | Interleukins - antagonists & inhibitors | Mice, Knockout | Spinal Cord - immunology | Interleukin-4 - immunology | Receptors, Nicotinic - immunology | Glycoproteins - immunology | Mice | alpha7 Nicotinic Acetylcholine Receptor | Tumor Necrosis Factor-alpha - metabolism | RNA, Messenger - immunology | Spinal Cord - drug effects | Encephalomyelitis, Autoimmune, Experimental - metabolism | GATA3 Transcription Factor - immunology | Interleukin-17 - immunology | NF-kappa B - immunology | T-Box Domain Proteins - immunology | Th1 Cells - immunology | Nicotine - pharmacology | Spinal Cord - pathology | Interleukins - immunology | Interferon-gamma - antagonists & inhibitors | Female | RNA, Messenger - drug effects | Receptors, Nicotinic - drug effects | Interleukin-4 - metabolism | Mice, Inbred C57BL | Antigen-Presenting Cells - immunology | Animals | Interleukin-17 - antagonists & inhibitors | Interferon-gamma - immunology | Cell Proliferation - drug effects | Receptors, Nicotinic - genetics | CD4-Positive T-Lymphocytes - drug effects | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Index Medicus | Abridged Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 09/2015, Volume 43, Issue 3, pp. 566 - 578
Three subsets of invariant natural killer T (iNKT) cells have been identified, NKT1, NKT2, and NKT17, which produce distinct cytokines when stimulated, but... 
ACTIVATION | HOMEOSTASIS | ALPHA-GALACTOSYLCERAMIDE | INVARIANT NKT CELLS | KILLER T-CELLS | ORPHAN RECEPTOR | IMMUNOLOGY | IDENTIFICATION | EXPRESSION | PROGRAM | CUTTING EDGE | Organ Specificity - drug effects | T-Lymphocyte Subsets - immunology | Spleen - immunology | T-Lymphocyte Subsets - cytology | Thymocytes - metabolism | Interferon-gamma - metabolism | Galactosylceramides - pharmacology | Lung - cytology | Organ Specificity - immunology | Liver - immunology | Lymphocyte Activation - immunology | Flow Cytometry | Natural Killer T-Cells - metabolism | Lung - metabolism | Thymus Gland - metabolism | Cytokines - immunology | Cytokines - metabolism | Interleukin-4 - metabolism | Liver - metabolism | Mice, Inbred C57BL | Cells, Cultured | Thymus Gland - cytology | Lymph Nodes - metabolism | Mice, Transgenic | Spleen - cytology | Lymph Nodes - immunology | Lymph Nodes - cytology | Natural Killer T-Cells - classification | Mice, Knockout | Thymocytes - immunology | Interleukin-4 - immunology | Animals | Galactosylceramides - immunology | Spleen - metabolism | Lymphocyte Activation - drug effects | T-Lymphocyte Subsets - metabolism | Interferon-gamma - immunology | Fluorescent Antibody Technique | Mice, Inbred NOD | Thymus Gland - immunology | Liver - cytology | Mice, Inbred BALB C | Lung - immunology | Natural Killer T-Cells - immunology | Cytokines | Biological response modifiers | T cells | Studies | Flow cytometry | Transcription factors | Statistical analysis | Lymphocytes | Rodents | Lipids | T cell receptors | Software | Experiments | Index Medicus
Journal Article
Nature Immunology, ISSN 1529-2908, 07/2015, Volume 16, Issue 8, pp. 859 - 870
The receptor NLRP3 is involved in the formation of the NLRP3 inflammasome that activates caspase-1 and mediates the release of interleukin 1β (IL-1β) and... 
NIH 3T3 Cells | Asthma - metabolism | Inflammasomes - metabolism | Oligonucleotide Array Sequence Analysis | NLR Family, Pyrin Domain-Containing 3 Protein | Interferon Regulatory Factors - metabolism | Gene Expression Profiling | Th2 Cells - immunology | Promoter Regions, Genetic - genetics | CD4-Positive T-Lymphocytes - immunology | Cell Differentiation - genetics | Signal Transduction - immunology | Neoplasms, Experimental - immunology | Asthma - immunology | Neoplasms, Experimental - genetics | Trans-Activators - genetics | Female | Interleukin-4 - genetics | Carrier Proteins - immunology | Trans-Activators - immunology | Interleukin-4 - metabolism | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Interferon Regulatory Factors - genetics | Gene Expression Regulation, Neoplastic - immunology | Signal Transduction - genetics | Protein Binding - immunology | Reverse Transcriptase Polymerase Chain Reaction | Th2 Cells - metabolism | Asthma - genetics | Blotting, Western | Inflammasomes - genetics | Mice, Knockout | Carrier Proteins - genetics | Cell Differentiation - immunology | Interleukin-4 - immunology | Interferon Regulatory Factors - immunology | Animals | Carrier Proteins - metabolism | Inflammasomes - immunology | Cell Line, Tumor | Trans-Activators - metabolism | Mice | Neoplasms, Experimental - metabolism | Promoter Regions, Genetic - immunology | Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 03/2013, Volume 38, Issue 3, pp. 570 - 580
Monocytes and macrophages are important effectors and regulators of inflammation, and both can be divided into distinct subsets based on their phenotypes. The... 
ALTERNATIVELY ACTIVATED MACROPHAGES | TYPE-2 INFLAMMATION | DENDRITIC CELLS | IMMUNE-RESPONSES | BONE-MARROW | CHEMOKINE RECEPTOR | PRODUCE INTERLEUKIN-4 | BACTERIAL-INFECTION | IL-4 PRODUCTION | IMMUNOLOGY | T-CELLS | Receptors, CCR2 - genetics | Receptors, CCR2 - immunology | Skin - metabolism | Antigens, Ly - genetics | Hypersensitivity - immunology | Monocytes - metabolism | Monocytes - immunology | Adoptive Transfer | Interleukin-4 Receptor alpha Subunit - genetics | Cell Differentiation - genetics | Inflammation - metabolism | Flow Cytometry | Hypersensitivity - metabolism | Basophils - immunology | Antigens, Ly - metabolism | Hypersensitivity - genetics | Macrophages - immunology | Skin - pathology | Skin - immunology | Interleukin-4 Receptor alpha Subunit - metabolism | Interleukin-4 - metabolism | Mice, Inbred C57BL | Cells, Cultured | Inflammation - immunology | Reverse Transcriptase Polymerase Chain Reaction | Interleukin-4 Receptor alpha Subunit - immunology | Mice, Knockout | Cell Differentiation - immunology | Interleukin-4 - immunology | Macrophages - metabolism | Receptors, CCR2 - metabolism | Animals | Antigens, Ly - immunology | Inflammation - genetics | Mice | Mice, Inbred BALB C | Basophils - metabolism | Anti-inflammatory drugs | Skin | Genetic aspects | Bone marrow | Wound healing | Cytokines | Allergies | Immune system | Index Medicus
Journal Article
Hepatology, ISSN 0270-9139, 06/2007, Volume 45, Issue 6, pp. 1538 - 1546
Journal Article
Immunity, ISSN 1074-7613, 11/2013, Volume 39, Issue 5, pp. 976 - 985
Journal Article