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The Journal of Immunology, ISSN 0022-1767, 11/2009, Volume 183, Issue 10, pp. 6469 - 6477
Alternatively activated macrophages (AAM) play a crucial role in type 2 immunity. Mice deficient in ST2, a receptor for the latest member of the IL-1 family,... 
IL-1-LIKE CYTOKINE IL-33 | IMMUNE-RESPONSE | ST2 RECEPTOR | EFFECTOR FUNCTION | MAST-CELLS | IN-VIVO | INDUCED ARTHRITIS | ALVEOLAR MACROPHAGES | INTERLEUKIN-1 RECEPTOR | IMMUNOLOGY | T-CELLS | Interleukin-1 Receptor-Like 1 Protein | Asthma - metabolism | Epithelial Cells - metabolism | Ovalbumin - immunology | Humans | Middle Aged | Chemokine CCL24 - metabolism | Interleukin-13 - immunology | Male | Interleukins - metabolism | Receptors, Interleukin - metabolism | Signal Transduction - immunology | Inflammation - metabolism | Interleukins - immunology | Asthma - immunology | Chemokine CCL17 - immunology | Adult | Female | Interleukin-4 - genetics | Macrophages, Alveolar - immunology | Recombinant Proteins - metabolism | Cell Polarity - immunology | Lung - pathology | Receptors, Interleukin - immunology | Interleukin-33 | Macrophage Activation - immunology | Receptors, Interleukin-1 - immunology | Interleukin-4 - metabolism | Receptors, Interleukin-4 - metabolism | Inflammation - immunology | Receptors, Interleukin-4 - immunology | Interleukin-13 - metabolism | Chemokine CCL24 - immunology | Receptors, Interleukin - genetics | Mice, Knockout | Receptors, Interleukin-1 - metabolism | Interleukin-4 - immunology | Animals | Eosinophilia - immunology | Recombinant Proteins - immunology | Epithelial Cells - immunology | Receptors, Interleukin-4 - genetics | Mice | Mice, Inbred BALB C | Macrophages, Alveolar - metabolism | Chemokine CCL17 - metabolism | Lung - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Molecular Immunology, ISSN 0161-5890, 07/2013, Volume 54, Issue 3-4, pp. 482 - 492
► Oral treatment with α,β-amyrin ameliorate disease activity in DSS-induced colitis. ► α,β-Amyrin treatment decrease leukocyte influx to the colon. ► The... 
Inflammatory bowel disease | α,β-Amyrin | Dextran sodium sulfate | Inflammatory cytokines | Cannabinoid system | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | alpha,beta-amyrin | MECHANISMS | BETA-AMYRIN | ADHESION MOLECULES | IMMUNOLOGY | PROTIUM-HEPTAPHYLLUM | ALPHA-AMYRIN | INFLAMMATORY-BOWEL-DISEASE | MOUSE MODEL | RECEPTORS | EXPRESSION | P-Selectin - metabolism | Colitis - genetics | Tumor Necrosis Factor-alpha - genetics | Colon - drug effects | Body Weight - drug effects | Ki-67 Antigen - metabolism | Male | Interleukin-1beta - genetics | Antigens, CD - genetics | Body Weight - genetics | Antigens, CD - metabolism | Lectins, C-Type - metabolism | Interleukin-1beta - metabolism | Cannabinoids - genetics | Colitis - drug therapy | Cannabinoids - metabolism | Administration, Oral | CD18 Antigens - genetics | Membrane Proteins - genetics | Asialoglycoproteins - metabolism | P-Selectin - genetics | Cell Adhesion Molecules - metabolism | Chemokines - genetics | Colon - metabolism | CD18 Antigens - metabolism | Intercellular Adhesion Molecule-1 - metabolism | Receptor, Cannabinoid, CB1 - genetics | Ki-67 Antigen - genetics | Intercellular Adhesion Molecule-1 - genetics | Colitis - metabolism | Chemokines - metabolism | Mice | Vascular Cell Adhesion Molecule-1 - metabolism | Tumor Necrosis Factor-alpha - metabolism | Dextran Sulfate | Cell Adhesion Molecules - genetics | Oleanolic Acid - analogs & derivatives | Oleanolic Acid - pharmacology | Lectins, C-Type - genetics | Receptor, Cannabinoid, CB2 - genetics | Asialoglycoproteins - genetics | Colitis - chemically induced | Vascular Cell Adhesion Molecule-1 - genetics | Membrane Proteins - metabolism | Interleukin-4 - genetics | Amidohydrolases - metabolism | Amidohydrolases - genetics | Interleukin-4 - metabolism | RNA, Messenger - genetics | Up-Regulation - genetics | Antigens, Differentiation, Myelomonocytic - genetics | Up-Regulation - drug effects | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Animals | Antigens, Differentiation, Myelomonocytic - metabolism | Peroxidase - genetics | Peroxidase - metabolism | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 02/2009, Volume 113, Issue 7, pp. 1526 - 1534
Journal Article
Diabetes, ISSN 0012-1797, 03/2016, Volume 65, Issue 3, pp. 598 - 609
Journal Article
Immunity, ISSN 1074-7613, 03/2013, Volume 38, Issue 3, pp. 570 - 580
Monocytes and macrophages are important effectors and regulators of inflammation, and both can be divided into distinct subsets based on their phenotypes. The... 
ALTERNATIVELY ACTIVATED MACROPHAGES | TYPE-2 INFLAMMATION | DENDRITIC CELLS | IMMUNE-RESPONSES | BONE-MARROW | CHEMOKINE RECEPTOR | PRODUCE INTERLEUKIN-4 | BACTERIAL-INFECTION | IL-4 PRODUCTION | IMMUNOLOGY | T-CELLS | Receptors, CCR2 - genetics | Receptors, CCR2 - immunology | Skin - metabolism | Antigens, Ly - genetics | Hypersensitivity - immunology | Monocytes - metabolism | Monocytes - immunology | Adoptive Transfer | Interleukin-4 Receptor alpha Subunit - genetics | Cell Differentiation - genetics | Inflammation - metabolism | Flow Cytometry | Hypersensitivity - metabolism | Basophils - immunology | Antigens, Ly - metabolism | Hypersensitivity - genetics | Macrophages - immunology | Skin - pathology | Skin - immunology | Interleukin-4 Receptor alpha Subunit - metabolism | Interleukin-4 - metabolism | Mice, Inbred C57BL | Cells, Cultured | Inflammation - immunology | Reverse Transcriptase Polymerase Chain Reaction | Interleukin-4 Receptor alpha Subunit - immunology | Mice, Knockout | Cell Differentiation - immunology | Interleukin-4 - immunology | Macrophages - metabolism | Receptors, CCR2 - metabolism | Animals | Antigens, Ly - immunology | Inflammation - genetics | Mice | Mice, Inbred BALB C | Basophils - metabolism | Anti-inflammatory drugs | Skin | Genetic aspects | Bone marrow | Wound healing | Cytokines | Allergies | Immune system | Index Medicus
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2010, Volume 107, Issue 52, pp. 22593 - 22598
We investigated the mechanisms by which T-cell cytokines are able to influence the Toll-like receptor (TLR)-induced, vitamin D-dependent antimicrobial pathway... 
T lymphocytes | Up regulation | Monocytes | Messenger RNA | Cytokines | Vitamin D | Mycobacterium tuberculosis | Antimicrobials | Small interfering RNA | Physiological regulation | Interleukin-4 | Interferon-γ | Innate immune response | interleukin-4 | MYCOBACTERIUM-TUBERCULOSIS | ACTIVATION | CATHELICIDIN | IFN-GAMMA | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | AUTOPHAGY | CUTTING EDGE | TOLL-LIKE RECEPTOR-2 | innate immune response | MICROBIAL LIPOPROTEINS | interferon-gamma | Steroid Hydroxylases - metabolism | Gene Expression - drug effects | Monocytes - cytology | Humans | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - genetics | Monocytes - metabolism | Antimicrobial Cationic Peptides - metabolism | Th1 Cells - metabolism | Interleukin-4 - pharmacology | T-Lymphocytes - metabolism | Calcitriol - metabolism | beta-Defensins - metabolism | Antimicrobial Cationic Peptides - genetics | Steroid Hydroxylases - genetics | beta-Defensins - genetics | Toll-Like Receptor 1 - metabolism | Cells, Cultured | 25-Hydroxyvitamin D3 1-alpha-Hydroxylase - metabolism | Vitamin D3 24-Hydroxylase | Toll-Like Receptor 2 - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Th2 Cells - metabolism | Blotting, Western | Monocytes - drug effects | Signal Transduction - drug effects | Vitamin D - analogs & derivatives | Vitamin D - metabolism | Cytokines - pharmacology | Interferon-gamma - pharmacology | Immune response | Calcifediol | Regulation | Alfacalcidol | Research | T cells | Properties | Health aspects | Signal transduction | Peptides | Metabolism | Gene expression | Cells | Index Medicus | Biological Sciences | interferon-γ
Journal Article
Journal Article
Molecular Cancer, ISSN 1476-4598, 09/2011, Volume 10, Issue 1, pp. 117 - 117
Journal Article
Journal Article
Cell, ISSN 0092-8674, 2008, Volume 132, Issue 2, pp. 259 - 272
Interleukin-4 and Interleukin-13 are cytokines critical to the development of T cell-mediated humoral immune responses, which are associated with allergy and... 
MOLIMMUNO | SIGNALING | SEVERE COMBINED IMMUNODEFICIENCY | COMPLEX | ALPHA-CHAIN | JUXTAMEMBRANE DOMAIN | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMMON GAMMA-CHAIN | IL-4 RECEPTOR | THERAPEUTIC TARGETS | FUNCTIONAL COMPONENT | BINDING | CELL BIOLOGY | Phosphorylation | Receptors, Interleukin-4 - chemistry | Humans | Molecular Sequence Data | Crystallography, X-Ray | Histidine - metabolism | Receptors, Interleukin-13 - metabolism | Dose-Response Relationship, Drug | Thermodynamics | Interleukin-13 - genetics | Interleukin-4 - pharmacology | Molecular Mimicry | X-Ray Diffraction | Interleukin-13 - isolation & purification | Receptors, Interleukin-13 - chemistry | Interleukin-4 - genetics | Receptors, Cytokine - metabolism | Binding Sites | Dimerization | STAT3 Transcription Factor - metabolism | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Amino Acid Sequence | Cell Line | Protein Structure, Secondary | Signal Transduction | Interleukin-4 - metabolism | Receptors, Interleukin-4 - metabolism | Models, Molecular | STAT6 Transcription Factor - metabolism | Interleukin-13 - metabolism | Interleukin-13 - pharmacology | Sequence Homology, Amino Acid | Tyrosine - metabolism | Interleukin-4 - isolation & purification | Hydrogen Bonding | Receptors, Cytokine - chemistry | Cell Line, Tumor | Hydrophobic and Hydrophilic Interactions | Protein Binding | Ligands | Kinetics | Cytokines | Interleukins | Physiological aspects | Index Medicus
Journal Article