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Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 130, Issue 2, pp. 516 - 522.e4
Journal Article
Immunity, ISSN 1074-7613, 03/2013, Volume 38, Issue 3, pp. 570 - 580
Journal Article
Inflammation, ISSN 0360-3997, 8/2013, Volume 36, Issue 4, pp. 921 - 931
Murine macrophages are activated by interferon-γ (IFN-γ) and/or Toll-like receptor (TLR) agonists such as bacterial endotoxin (lipopolysaccharide [LPS]) to... 
Pathology | alternative activation | Medicine & Public Health | Rheumatology | adenosine receptor | Internal Medicine | macrophage | TLR | Pharmacology/Toxicology | IL-4Rα | ACTIVATION | A(2A) RECEPTORS | C/EBP-BETA | IL-10 PRODUCTION | INJURY | IL-4R alpha | IMMUNOLOGY | MURINE | CELL BIOLOGY | REPAIR | LIPOPOLYSACCHARIDE | TRANSCRIPTIONAL REGULATION | EXPRESSION | Vascular Endothelial Growth Factor A - biosynthesis | Nitric Oxide Synthase Type II - biosynthesis | Mannose-Binding Lectins - biosynthesis | Arginase - biosynthesis | Intercellular Signaling Peptides and Proteins - biosynthesis | Male | Lectins, C-Type - biosynthesis | Lectins - biosynthesis | Interleukin-4 Receptor alpha Subunit - genetics | Cell Differentiation | Receptors, Cell Surface - biosynthesis | Macrophages - immunology | Interleukin-12 - biosynthesis | Interleukin-4 Receptor alpha Subunit - metabolism | Signal Transduction | Purinergic P1 Receptor Agonists - pharmacology | Cells, Cultured | Mice, Transgenic | Adenosine - pharmacology | Receptor, Adenosine A2A - metabolism | beta-N-Acetylhexosaminidases - biosynthesis | Neovascularization, Physiologic - immunology | Macrophage Activation | Animals | Adenosine - metabolism | Interleukin-10 - biosynthesis | Macrophages - drug effects | Mice | Mice, Inbred BALB C | Tumor Necrosis Factor-alpha - biosynthesis | Physiological aspects | Cell receptors | Genetic aspects | Cellular signal transduction | Research | Macrophages | IL4Rα | Alternative Activation | Adenosine Receptor | Macrophage
Journal Article
Nature Immunology, ISSN 1529-2908, 08/2014, Volume 15, Issue 10, pp. 938 - 946
We examined the role of innate cells in acquired resistance to the natural murine parasitic nematode, Nippostrongylus brasiliensis. Macrophages obtained from... 
ADAPTIVE IMMUNITY | ALTERNATIVELY ACTIVATED MACROPHAGES | PROTECTIVE IMMUNITY | INTESTINAL NEMATODE PARASITES | LARVAL STRONGYLOIDES-STERCORALIS | INNATE | INFECTION | IMMUNOLOGY | NIPPOSTRONGYLUS-BRASILIENSIS | T-CELLS | HOST PROTECTION | Oligonucleotide Array Sequence Analysis | Strongylida Infections - genetics | Interleukin-13 - immunology | Disease Resistance - immunology | Transcriptome - immunology | Nippostrongylus - immunology | Interleukin-4 Receptor alpha Subunit - genetics | Interleukin-13 - genetics | Flow Cytometry | Larva - immunology | Strongylida Infections - parasitology | Strongylida Infections - immunology | Female | Lung - metabolism | Adaptive Immunity - immunology | Cytokines - genetics | Neutrophils - metabolism | Macrophages - immunology | Cytokines - immunology | Interleukin-4 Receptor alpha Subunit - metabolism | Cytokines - metabolism | Lung - parasitology | Cells, Cultured | Neutrophils - immunology | Host-Parasite Interactions - immunology | Interleukin-13 - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Interleukin-4 Receptor alpha Subunit - immunology | Mice, Knockout | Cell Adhesion - immunology | Macrophages - metabolism | Animals | Nippostrongylus - physiology | Cell Adhesion - physiology | Mice, Inbred BALB C | Larva - physiology | Lung - immunology | Host-parasite relationships | Genetic aspects | Immune response | Properties | Macrophages | Neutrophils | Index Medicus | Parasite | macrophage | type 2 response | helminth | neutrophil | TH2 cytokines
Journal Article
Journal Article
Journal of Clinical Endocrinology and Metabolism, ISSN 0021-972X, 05/2017, Volume 102, Issue 5, pp. 1468 - 1477
Context: Increasing evidences suggest a correlation between gut and type 1 diabetes (T1D). Objective: The objective of this study is to evaluate the gut... 
INCREASED INTESTINAL PERMEABILITY | HEALTHY-CHILDREN | DIFFERS | FECAL MICROBIOTA | DISEASE | ENDOCRINOLOGY & METABOLISM | CELL AUTOIMMUNITY | GUT MICROBIOTA | MELLITUS | ONSET | Receptors, CCR2 - genetics | Serum Amyloid P-Component - immunology | Receptors, CCR2 - immunology | Humans | Middle Aged | Tumor Necrosis Factor-alpha - genetics | Transcriptome | Child, Preschool | Male | Monocyte Chemoattractant Proteins - immunology | Vascular Endothelial Growth Factor A - genetics | Antigens, CD - genetics | Interleukin-4 Receptor alpha Subunit - genetics | Young Adult | Celiac Disease - microbiology | Cyclooxygenase 2 - genetics | Intestinal Mucosa - immunology | Diabetes Mellitus, Type 1 - microbiology | Tumor Necrosis Factor-alpha - immunology | Child | Real-Time Polymerase Chain Reaction | Duodenum - immunology | Vascular Endothelial Growth Factor A - immunology | C-Reactive Protein - genetics | Intestinal Mucosa - microbiology | Reverse Transcriptase Polymerase Chain Reaction | Monocyte Chemoattractant Proteins - genetics | Chemokine CCL22 - genetics | Chemokine CCL19 - genetics | Adolescent | RNA, Ribosomal, 16S - genetics | C-Reactive Protein - immunology | Antigens, CD - immunology | Infant | Case-Control Studies | Duodenum - microbiology | Chemokine CCL22 - immunology | Celiac Disease - immunology | Adult | Female | Diabetes Mellitus, Type 1 - immunology | Chemokine CCL19 - immunology | Cyclooxygenase 2 - immunology | Antigens, Differentiation, Myelomonocytic - immunology | Diabetes Mellitus, Type 1 - genetics | Gastrointestinal Microbiome - genetics | Interleukin-4 Receptor alpha Subunit - immunology | Antigens, Differentiation, Myelomonocytic - genetics | Serum Amyloid P-Component - genetics | Aged | Immunohistochemistry | CC chemokine receptors | rRNA 16S | CCL19 protein | Pathogenesis | Mucosa | Microbiomes | Diabetes mellitus (insulin dependent) | Macrophages | Small intestine | Gene sequencing | CCL22 protein | Microbiota | CCR2 protein | Intestine | Interleukin 4 receptors | Digestive tract | Duodenum | Digestive system | Abnormalities | Diabetes mellitus | Inflammation | Tumor necrosis factor-α | Gene expression | Ribonucleic acid--RNA | Disease control | Patients | Celiac disease | Biopsy | Infiltration | Diabetes | Cyclooxygenase-2 | Autoimmune diseases | Monocyte chemoattractant protein 1
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 09/2016, Volume 22, Issue 9, pp. 1013 - 1022
Mechanisms by which regulatory T (Treg) cells fail to control inflammation in asthma remain poorly understood. We show that a severe asthma-associated... 
GRB2 Adaptor Protein - immunology | Immunoprecipitation | Humans | Middle Aged | Interleukin-17 - immunology | Interleukin-13 - immunology | Immunoblotting | Male | Gene Expression Profiling | Case-Control Studies | Interleukin-4 Receptor alpha Subunit - genetics | T-Lymphocytes, Regulatory - immunology | Young Adult | Th17 Cells - drug effects | Flow Cytometry | Asthma - immunology | Adult | Female | Receptors, Interleukin-6 - immunology | Child | Real-Time Polymerase Chain Reaction | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Disease Models, Animal | Nuclear Receptor Subfamily 1, Group F, Member 3 - immunology | Receptors, Interleukin-6 - genetics | Antibodies, Neutralizing - pharmacology | Inflammation - immunology | Respiratory Hypersensitivity - immunology | Reverse Transcriptase Polymerase Chain Reaction | Interleukin-4 Receptor alpha Subunit - immunology | Asthma - genetics | Polymorphism, Genetic | Cell Differentiation - immunology | T-Lymphocytes, Regulatory - drug effects | Animals | Cell Differentiation - drug effects | Adolescent | Interleukin-6 - immunology | Th17 Cells - immunology | Mice | STAT3 Transcription Factor - immunology | Lung - immunology | Receptors, Cell Surface - genetics | Complications and side effects | Airway obstruction (Medicine) | T cells | Analysis | Risk factors | Asthma | Airway management | Inflammatory diseases | Cells
Journal Article
Science Signaling, ISSN 1945-0877, 11/2015, Volume 8, Issue 402, pp. ra114 - ra114
Journal Article
Circulation Research, ISSN 0009-7330, 02/2015, Volume 116, Issue 5, pp. 804 - 815
RATIONALE:Neonatal mice have the capacity to regenerate their hearts in response to injury, but this potential is lost after the first week of life. The... 
Regeneration | Growth factors/cytokines | Cardiac myocyte | Gene expression | Myogenesis | SIGNALING PATHWAYS | CARDIAC & CARDIOVASCULAR SYSTEMS | growth factors | CARDIOMYOCYTE CELL-CYCLE | regeneration | MOUSE | INJURY | PROLIFERATION | ZEBRAFISH HEART REGENERATION | DNA-SYNTHESIS | LARGE GENE LISTS | cardiac myocyte | RNA-SEQ | FUNCTIONAL-ANALYSIS | PERIPHERAL VASCULAR DISEASE | cytokines | myogenesis | HEMATOLOGY | gene expression | Heart Ventricles - cytology | Interleukin-13 - physiology | Cell Adhesion Molecules - physiology | Transcriptome | Culture Media, Serum-Free | Gene Regulatory Networks | Interleukin-13 Receptor alpha1 Subunit - antagonists & inhibitors | Interleukin-4 Receptor alpha Subunit - genetics | Muscle Development | STAT3 Transcription Factor - physiology | RNA Interference | Gene Expression Regulation, Developmental | STAT6 Transcription Factor - physiology | Transcription, Genetic | Cell Differentiation | Animals, Newborn | Transcription Factors - physiology | RNA, Small Interfering - pharmacology | Cells, Cultured | Rats | DNA Replication | Interleukin-4 Receptor alpha Subunit - antagonists & inhibitors | Interleukin-13 - pharmacology | Regeneration - physiology | Rats, Sprague-Dawley | Interleukin-13 Receptor alpha1 Subunit - genetics | Sequence Alignment | Animals | Myocytes, Cardiac - drug effects | Cell Cycle | Myocytes, Cardiac - metabolism | Mice | Cell Dedifferentiation - genetics
Journal Article
Journal Article