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Cytokine, ISSN 1043-4666, 05/2016, Volume 81, pp. 1 - 9
•Two loci identified for IL-5 levels on chromosomes and 14.•One locus on chromosome 5 was identified for eosinophil count.•The chromosome 5 loci are in close... 
Intima-media thickness | Genetics | IL-5 | RAD50 | Subclinical atherosclerosis | Eosinophil count | IMMUNITY | MYOCARDIAL-INFARCTION | VARIANTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUSCEPTIBILITY | RECEPTOR | IMMUNOLOGY | IDENTIFICATION | CELL BIOLOGY | INFLAMMATION | ARCHITECTURE | COMMON | Eosinophils - metabolism | Plaque, Atherosclerotic - genetics | Humans | Middle Aged | DNA Repair Enzymes - genetics | Genetic Loci - genetics | Male | Interleukin-5 - genetics | Coronary Artery Disease - blood | Female | Leukocyte Count | Plaque, Atherosclerotic - blood | Chromosomes, Human, Pair 5 - genetics | Genetics, Population | Gene Expression | Genetic Predisposition to Disease - genetics | Carotid Intima-Media Thickness | Europe | Risk Factors | Linear Models | DNA-Binding Proteins - genetics | Interleukin-5 - blood | Coronary Artery Disease - genetics | Aged | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Chromosomes, Human, Pair 14 - genetics | Genetic aspects | Interleukins | Cardiovascular diseases | Risk factors | IMT-Bifmean, mean of IMT measures in the carotid bifurcation | IMTmean-max, mean of the maximum IMT measures along the entire carotid tree | IMT-CCmax, max of IMT measures in the common carotid | IMT-CCmean, mean of IMT measures in the common carotid | IMT-Bifmax, max of IMT measures in the carotid bifurcation | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
Immunity, ISSN 1074-7613, 03/2015, Volume 42, Issue 3, pp. 538 - 551
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 135, Issue 6, pp. 1594 - 1602
Background Thymic stromal lymphopoietin (TSLP) and IL-33 are considered important initiators of type 2 immunity. In asthmatic patients allergic inflammatory... 
Allergy and Immunology | Hematopoietic progenitor cells | thymic stromal lymphopoietin | asthma | BONE-MARROW | AIRWAY INFLAMMATION | INTERLEUKIN-13 | EOSINOPHIL PROGENITORS | IMMUNOLOGY | RESPONSES | FACTOR-1-ALPHA | ALLERGY | SPUTUM EOSINOPHILIA | DISEASE | EXACERBATIONS | CORTICOSTEROIDS | Interleukin-1 Receptor-Like 1 Protein | Sputum - cytology | Eosinophils - drug effects | Humans | Middle Aged | Hematopoietic Stem Cells - pathology | Interleukin-13 - immunology | Male | Interleukin-7 Receptor alpha Subunit - immunology | Interleukin-5 - genetics | Eosinophils - immunology | Forced Expiratory Volume | Interleukins - genetics | Hematopoietic Stem Cells - immunology | Interleukin-13 - genetics | Interleukin-13 Receptor alpha1 Subunit - immunology | Sputum - immunology | Chemokine CXCL12 - genetics | Interleukins - immunology | Methacholine Chloride - pharmacology | Asthma - immunology | Adult | Eosinophils - pathology | Interleukin-7 Receptor alpha Subunit - genetics | Cytokines - genetics | Receptors, Cytokine - genetics | Chemokine CXCL12 - immunology | Cytokines - immunology | Hematopoietic Stem Cells - drug effects | Interleukin-33 | Gene Expression Regulation | Administration, Inhalation | Immunity, Innate | Receptors, Cell Surface - immunology | Asthma - genetics | Interleukin-13 Receptor alpha1 Subunit - genetics | Interleukin-5 - immunology | Cell Movement - drug effects | Receptors, Cytokine - immunology | Allergens - pharmacology | Primary Cell Culture | Asthma - pathology | Receptors, Cell Surface - genetics | Care and treatment | Asthma | Studies | Flow cytometry | Airway management | Cytokines | Pathogenesis | Migration | Family medical history | Allergies
Journal Article
Mucosal Immunology, ISSN 1933-0219, 01/2016, Volume 9, Issue 1, pp. 275 - 286
Journal Article
Mucosal Immunology, ISSN 1933-0219, 05/2015, Volume 8, Issue 3, pp. 545 - 558
Mucosal tissues contain large numbers of memory CD4(+) T cells that, through T-cell receptor-dependent interactions with antigen-presenting cells, are believed... 
EFFECTOR | INFLAMMATORY-BOWEL-DISEASE | CROHNS-DISEASE | IFN-GAMMA | IMMUNE-RESPONSES | IL-18 | INTERLEUKIN-15 | CYTOKINE | IMMUNOLOGY | EXPRESSION | TL1A | Crohn Disease - genetics | Skin - cytology | Receptors, Tumor Necrosis Factor, Member 25 - immunology | Humans | Tumor Necrosis Factor-alpha - genetics | Immunity, Mucosal | Interleukin-13 - immunology | Interleukin-5 - genetics | CD4-Positive T-Lymphocytes - pathology | Interleukin-15 - immunology | CD4-Positive T-Lymphocytes - immunology | Interleukins - genetics | Interleukin-13 - genetics | Intestinal Mucosa - immunology | Interleukins - immunology | Nasal Polyps - genetics | Tumor Necrosis Factor-alpha - immunology | Interferon-gamma - genetics | Receptors, Tumor Necrosis Factor, Member 25 - genetics | Tumor Necrosis Factor Ligand Superfamily Member 15 - genetics | Skin - immunology | Nasal Polyps - immunology | Nasal Polyps - pathology | Interleukin-6 - genetics | Signal Transduction | Gene Expression Regulation | Epithelial Cells - pathology | Immunity, Innate | Crohn Disease - immunology | Tumor Necrosis Factor Ligand Superfamily Member 15 - immunology | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Interleukin-5 - immunology | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Interleukin-15 - genetics | Crohn Disease - pathology | Epithelial Cells - immunology | Interferon-gamma - immunology | Interleukin-6 - immunology | Receptors, Interleukin-18 - genetics | Immunologic Memory | Receptors, Interleukin-18 - immunology | Primary Cell Culture | Intestinal Mucosa - pathology | Basic Medicine | Immunologi inom det medicinska området | Medical and Health Sciences | Medicin och hälsovetenskap | Immunology in the medical area | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Immunity, ISSN 1074-7613, 12/2017, Volume 47, Issue 6, pp. 1154 - 1168.e6
White adipose tissue bridges body organs and plays a fundamental role in host metabolism. To what extent adipose tissue also contributes to immune surveillance... 
effector memory T cells | resident memory T cells | infection | lipids | memory | adipose tissue | metabolism | T cells | adipocytes | central memory T cells | central memory T cells | effector memory T cells | resident memory T cells | MIGRATION | IMMUNE-RESPONSE | LOCALIZATION | SUPPORT | CYTOKINES | METABOLIC HOMEOSTASIS | DENDRITIC CELLS | PERMEABILITY | INFLAMMATION | FAT | IMMUNOLOGY | Toxoplasma - immunology | Yersinia pseudotuberculosis Infections - immunology | Adipose Tissue, White - immunology | Adipose Tissue, White - transplantation | Toxoplasmosis - immunology | Tumor Necrosis Factor-alpha - genetics | CD8-Positive T-Lymphocytes - parasitology | Interleukin-17 - immunology | Toxoplasmosis - mortality | Interleukin-5 - genetics | CD4-Positive T-Lymphocytes - parasitology | Toxoplasmosis - parasitology | CD4-Positive T-Lymphocytes - immunology | Tissue Transplantation | Tumor Necrosis Factor-alpha - immunology | Interferon-gamma - genetics | Genes, Reporter | Yersinia pseudotuberculosis - immunology | Yersinia pseudotuberculosis Infections - genetics | Gene Expression | CD4-Positive T-Lymphocytes - microbiology | CD8-Positive T-Lymphocytes - microbiology | Mice, Inbred C57BL | Bacterial Proteins - genetics | Interleukin-17 - genetics | Lipid Metabolism | Mice, Transgenic | Yersinia pseudotuberculosis Infections - mortality | Interleukin-5 - immunology | Animals | Yersinia pseudotuberculosis Infections - microbiology | Interferon-gamma - immunology | Survival Analysis | Bacterial Proteins - metabolism | Immunologic Memory | Luminescent Proteins - genetics | Toxoplasmosis - genetics | Mice | CD8-Positive T-Lymphocytes - immunology | Luminescent Proteins - metabolism | Adipose tissues | Lipids | Microbiology | Parasitic diseases | Health aspects | Pathogens | Memory cells | Immunological memory | Adipose tissue | Memory | Organs | Immunosurveillance | Lymphocytes T | Infections | Metabolism | Cells | Tissue | Immunology | Bioaccumulation | Lymphocytes | Lipid metabolism
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2015, Volume 10, Issue 9, p. e0137699
The transcription factor PU.1 is predominantly expressed in dendritic cells (DCs) and is essential for DC differentiation. Although there are several reports... 
RESPONSE ELEMENT | PROGENITORS | COMPLEX | REPRESSION | MULTIDISCIPLINARY SCIENCES | MAST-CELLS | MOUSE | INVOLVEMENT | DIFFERENTIATION | IDENTIFICATION | IL-4 GENE-EXPRESSION | GATA3 Transcription Factor - genetics | RNA, Small Interfering - genetics | Exons | Interleukin-5 - genetics | Gene Knockdown Techniques | Interleukin-13 - genetics | Nucleotide Motifs | Trans-Activators - genetics | Acetylation | Cytokines - genetics | Dendritic Cells - metabolism | GATA2 Transcription Factor - genetics | Proto-Oncogene Proteins - metabolism | Promoter Regions, Genetic | Cytokines - metabolism | Interleukin-5 - metabolism | Gene Expression Regulation | Gene Silencing | Histone Deacetylases - metabolism | Proto-Oncogene Proteins - genetics | Interleukin-13 - metabolism | GATA1 Transcription Factor - metabolism | Th2 Cells - metabolism | Amino Acid Motifs | Animals | GATA1 Transcription Factor - genetics | GATA2 Transcription Factor - metabolism | Protein Binding | Trans-Activators - metabolism | Mice | Histones - metabolism | Promoters (Genetics) | Research | Cytokines | Dendritic cells | Neutrophils | Histone deacetylase | Chromatin | Transcription factors | Immunoprecipitation | Laboratories | Science | Lymphocytes T | Lipopolysaccharides | Recruitment | PU.1 protein | Immunology | Interleukin 5 | Rodents | DNA methylation | Bone marrow | Trichostatin A | Interleukin 13 | siRNA | Gene expression | Medicine | Gene silencing | GATA-3 protein | Molecular biology | Histone H3
Journal Article
Nature Immunology, ISSN 1529-2908, 01/2014, Volume 15, Issue 1, pp. 36 - 44
Eosinophilia is a hallmark characteristic of T helper type 2 (T(H)2) cell-associated diseases and is critically regulated by the central eosinophil growth... 
RESPONSES | ALTERNATIVELY ACTIVATED MACROPHAGES | DENDRITIC CELLS | NK CELL RECOGNITION | PIR-B | BONE-MARROW | IN-VIVO | DISEASE | INHIBITORY RECEPTOR | MICE | IMMUNOLOGY | Stem Cells - immunology | GRB2 Adaptor Protein - immunology | Apoptosis - genetics | Male | Eosinophils - immunology | Extracellular Signal-Regulated MAP Kinases - immunology | Asthma - immunology | Gene Expression - immunology | Apoptosis Regulatory Proteins - immunology | Membrane Proteins - genetics | Mice, Transgenic | Signal Transduction - genetics | Reverse Transcriptase Polymerase Chain Reaction | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Interleukin-5 - immunology | Cell Differentiation - immunology | Mice | Receptors, Immunologic - genetics | Asthma - metabolism | Eosinophils - metabolism | Stem Cells - cytology | Extracellular Signal-Regulated MAP Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Colony-Forming Units Assay - methods | Cell Differentiation - genetics | Signal Transduction - immunology | Flow Cytometry | Bcl-2-Like Protein 11 | GRB2 Adaptor Protein - genetics | Proto-Oncogene Proteins - immunology | Apoptosis Regulatory Proteins - genetics | Female | Membrane Proteins - metabolism | Receptors, Immunologic - immunology | Proto-Oncogene Proteins - metabolism | Interleukin-5 - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Membrane Proteins - immunology | Proto-Oncogene Proteins - genetics | Asthma - genetics | Animals | Apoptosis - immunology | Cell Differentiation - drug effects | Stem Cells - drug effects | Eosinophils - cytology | GRB2 Adaptor Protein - metabolism | Receptors, Immunologic - metabolism | Biological research | Immune response | Research | Properties | Identification and classification | Interleukin-5 | Eosinophils | Biology, Experimental
Journal Article
Journal of General Virology, ISSN 0022-1317, 01/2018, Volume 99, Issue 1, pp. 135 - 147
The vectorization of rare human adenovirus (HAdV) types will widen our knowledge of this family and their interaction with cells, tissues and organs. In this... 
Vaccine vector | Gene therapy | Adenovirus | HAdV-56 | HIV-1 | CELLS | LIGAND-BINDING | SAFETY | INTEGRIN | gene therapy | RECEPTOR | SIALIC-ACID | vaccine vector | RESPONSES | IMMUNOGENICITY | VIROLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | adenovirus | EXPRESSION | Injections, Intravenous | Spleen - immunology | Gene Expression - drug effects | Chemokine CCL2 - immunology | Humans | Tumor Necrosis Factor-alpha - genetics | Vaccination | Spleen - drug effects | Interleukin-5 - genetics | Antibodies, Viral - blood | Chemokine CXCL10 - immunology | Tumor Necrosis Factor-alpha - immunology | Female | Interferon-gamma - genetics | Transgenes | Antibodies, Viral - biosynthesis | Viral Vaccines - biosynthesis | Genetic Vectors - chemistry | Genetic Vectors - immunology | Interleukin-6 - genetics | Adenoviruses, Human - immunology | Genetic Vectors - metabolism | Chemokine CCL2 - genetics | Chemokine CXCL9 - immunology | Chemokine CXCL9 - genetics | Viral Vaccines - administration & dosage | Interleukin-5 - immunology | Animals | Chemokine CXCL10 - genetics | Interferon-gamma - immunology | Lung - drug effects | Interleukin-6 - immunology | Adenoviruses, Human - genetics | Mice | Mice, Inbred BALB C | Lung - immunology | Genetic Therapy - methods | Index Medicus | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinsk bioteknologi | Mikrobiologi inom det medicinska området | Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy) | Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci) | Medical Biotechnology | Microbiology in the medical area | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Clinical & Experimental Immunology, ISSN 0009-9104, 09/2017, Volume 189, Issue 3, pp. 383 - 391
Summary Pyoderma gangrenosum (PG) is a rare, immune‐mediated skin disease classified into the group of neutrophilic dermatoses. Although a number of studies... 
skin | Autoinflammatory diseases | Th1/Th2 cells | cytokines | chemokines | GAMMA | CELLS | NEUTROPHILIC DERMATOSES | IL-15 | IMMUNOLOGY | AUTOINFLAMMATION | RESPONSES | EXPRESSION | Receptors, CCR3 - immunology | Interleukin-12 - genetics | Humans | Middle Aged | Th1-Th2 Balance | Interleukin-13 - immunology | Receptors, CCR5 - genetics | Male | Th2 Cells - immunology | Interleukin-5 - genetics | Th1 Cells - immunology | Interleukin-15 - immunology | CD40 Ligand - immunology | Receptors, CCR5 - immunology | CD56 Antigen - genetics | Interleukin-13 - genetics | Receptors, CCR3 - genetics | Adult | Female | Interferon-gamma - genetics | Interleukin-4 - genetics | CD56 Antigen - immunology | Skin - immunology | Sweet Syndrome - immunology | Pyoderma Gangrenosum - physiopathology | Sweet Syndrome - physiopathology | Interleukin-5 - immunology | Interleukin-4 - immunology | Interleukin-15 - genetics | CD40 Ligand - genetics | Interferon-gamma - immunology | Pyoderma Gangrenosum - immunology | Receptors, CXCR3 - genetics | Interleukin-12 - immunology | Receptors, CXCR3 - immunology | Aged | Killer cells | Interleukins | Analysis | Skin diseases | Skin | Interferon | Biological response modifiers | Immunohistochemistry | CD40 antigen | Pathogenesis | Interleukin | Innate immunity | Lymphocytes T | Immunity | CD40L protein | Interleukin 4 | Interleukin 5 | Sweet's syndrome | Natural killer cells | Lesions | CD56 antigen | Carbon-carbon composites | CCR5 protein | Aggressive behavior | Cytokines | Markers | Leukocytes (neutrophilic) | Interleukin 13 | CXCR3 protein | Interleukin 15 | Patients | Overexpression | Pyoderma | Chemokines | Pyoderma gangrenosum | Th1 | Th2 cells | Original
Journal Article