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Brain, Behavior, and Immunity, ISSN 0889-1591, 2015, Volume 51, pp. 204 - 211
Highlights • Endocannabinoids participate in the fever induced by TNF, IL-1β, IL-6, CRF and ET-1. • Endocannabinoids are not involved in the fever induced by... 
Psychiatry | Allergy and Immunology | Prostaglandins | Cytokines | β-Endorphin | Fever | Endocannabinoids | Anandamide | SYSTEM | ENDOGENOUS CANNABINOIDS | RECEPTOR-SELECTIVE ANTAGONIST | RATS | IMMUNOLOGY | NEUROSCIENCES | beta-Endorphin | ENDOTHELIAL-CELLS | INDEPENDENT FEVER | ANXIETY-LIKE | CANNABINOID 1 RECEPTORS | CB1 RECEPTORS | Narcotic Antagonists - administration & dosage | Rats, Wistar | Body Temperature - drug effects | Male | Fever - chemically induced | Cytokines - physiology | Fever - physiopathology | Receptor, Cannabinoid, CB1 - physiology | Endocannabinoids - physiology | Arachidonic Acids - administration & dosage | Interleukin-6 - physiology | Corticotropin-Releasing Hormone - administration & dosage | Interleukin-6 - administration & dosage | Arachidonic Acids - physiology | Interleukin-1beta - physiology | Piperidines - administration & dosage | beta-Endorphin - cerebrospinal fluid | Endothelin-1 - administration & dosage | Rats | Cytokines - administration & dosage | Polyunsaturated Alkamides - administration & dosage | Prostaglandins - physiology | Pyrazoles - administration & dosage | Animals | Endocannabinoids - administration & dosage | Interleukin-1beta - administration & dosage | Tumor Necrosis Factor-alpha - physiology | Tumor Necrosis Factor-alpha - administration & dosage | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Naloxone - administration & dosage | Prostaglandins - administration & dosage | Index Medicus
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 08/2007, Volume 176, Issue 4, pp. 395 - 400
Rationale: Exposure to combustion-derived air pollution is associated with an early (1-2 h) and sustained (24 h) rise in cardiovascular morbidity and... 
Air pollution | Inflammation | Diesel exhaust | Blood flow | Endothelium | endothelium | IMPAIRED ENDOGENOUS FIBRINOLYSIS | OXIDATIVE STRESS | MYOCARDIAL-INFARCTION | TERM EXPOSURE | PARTICLES | INFLAMMATORY RESPONSES | HEALTHY-HUMAN VOLUNTEERS | HUMAN AIRWAYS | CIGARETTE-SMOKING | inflammation | RESPIRATORY SYSTEM | diesel exhaust | PARTICULATE AIR-POLLUTION | air pollution | blood flow | CRITICAL CARE MEDICINE | Verapamil - blood | Humans | Tumor Necrosis Factor-alpha - blood | Male | Verapamil - administration & dosage | Interleukin-6 - blood | Forearm - blood supply | Adult | Vehicle Emissions | Bradykinin - blood | Vasodilation - physiology | Antioxidants - analysis | Double-Blind Method | Nitroprusside - administration & dosage | Endothelium, Vascular - physiopathology | Nitroprusside - analysis | Biomarkers - blood | Cross-Over Studies | Environmental Exposure - adverse effects | Vasodilator Agents - blood | Acetylcholine - administration & dosage | Acetylcholine - blood | Adolescent | P-Selectin - blood | Bradykinin - administration & dosage | Regional Blood Flow - physiology | Vasodilator Agents - administration & dosage | Inflammation - physiopathology | Index Medicus | Abridged Index Medicus | Inflammation/physiopathology | Nitroprusside/administration & dosage/analysis | P-Selectin/blood | Interleukin-6/blood | Acetylcholine/administration & dosage/blood | Verapamil/administration & dosage/blood | Endothelium; Vascular/physiopathology | Vasodilator Agents/administration & dosage/blood | Regional Blood Flow/physiology | Bradykinin/administration & dosage/blood | Forearm/blood supply | Vasodilation/physiology | Antioxidants/analysis | Biological Markers/blood | Tumor Necrosis Factor-alpha/blood | Environmental Exposure/adverse effects
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2013, Volume 8, Issue 11, pp. e79037 - e79037
Introduction: Acute kidney injury (AKI) and acute lung injury (ALI) are serious complications of sepsis. AKI is often viewed as a late complication of sepsis.... 
UNITED-STATES | CARDIAC-SURGERY | MULTIDISCIPLINARY SCIENCES | MECHANICAL VENTILATION | SEPTIC SHOCK | ACUTE-RENAL-FAILURE | MICE | BILATERAL-NEPHRECTOMY | INTERLEUKIN-6 | EPIDEMIOLOGY | RESPIRATORY-DISTRESS-SYNDROME | Acute-Phase Proteins - urine | Blood Urea Nitrogen | Interleukin-10 - blood | Lipocalins - urine | Antibodies, Monoclonal - therapeutic use | Male | Sepsis - complications | Interleukin-6 - urine | Lung - enzymology | Glomerular Filtration Rate - drug effects | Time Factors | Acute Kidney Injury - complications | Tumor Necrosis Factor-alpha - immunology | Acute Lung Injury - drug therapy | Acute Lung Injury - metabolism | Antibodies, Monoclonal - immunology | Oncogene Proteins - urine | Acute Kidney Injury - drug therapy | Mice, Inbred C57BL | Interleukin-6 - deficiency | Animals | Sepsis - chemically induced | Interleukin-6 - pharmacology | Lipocalin-2 | Lung - drug effects | Creatinine - blood | Endotoxins - administration & dosage | Mice | Acute Kidney Injury - metabolism | Endotoxins - toxicity | Acute Lung Injury - complications | Peroxidase - metabolism | Intensive care | Identification methods | Pathogenesis | Lung | Antibodies | Clinical trials | Critical care | Inflammatory response | Lipopolysaccharides | Interleukin 6 | Rodents | Inulin | Tumor necrosis factor-TNF | Peroxidase | Injuries | Urine | Creatinine | Hypertension | Kidneys | Cytokines | Complications | Mortality | Cecum | Markers | Neutrophils | Inflammation | Tumor necrosis factor-α | Glomerular filtration rate | Medicine | Studies | Sepsis | Kidney diseases | Laboratory animals | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 06/2014, Volume 123, Issue 26, pp. 4136 - 4142
Journal Article
British Journal of Haematology, ISSN 0007-1048, 05/2013, Volume 161, Issue 3, pp. 357 - 366
Interleukin‐6 ( IL 6) plays a central role in multiple myeloma pathogenesis and confers resistance to corticosteroid‐induced apoptosis. We therefore evaluated... 
dexamethasone | targeted therapy | siltuximab | multiple myeloma | interleukin‐6 | Siltuximab | Dexamethasone | Targeted therapy | Multiple myeloma | Interleukin-6 | APOPTOSIS | CNTO 328 | CELL-LINES | interleukin-6 | RECEPTOR ANTAGONIST | IL-6 | PRECLINICAL MODELS | GROWTH | THERAPEUTIC RESPONSE | HEMATOLOGY | Interleukin-6 - antagonists & inhibitors | Humans | Middle Aged | Pyrazines - administration & dosage | Antibodies, Monoclonal - adverse effects | Infection Control | Salvage Therapy | Antibodies, Monoclonal - therapeutic use | Drug Resistance, Neoplasm | Male | Antineoplastic Agents - therapeutic use | Multiple Myeloma - drug therapy | Antineoplastic Agents - adverse effects | Aged, 80 and over | Adult | Female | Antineoplastic Agents - pharmacology | Boronic Acids - administration & dosage | C-Reactive Protein - analysis | Antibodies, Monoclonal - immunology | Multiple Myeloma - blood | Hematologic Diseases - chemically induced | Bortezomib | Dexamethasone - administration & dosage | Drug Administration Schedule | Antibodies, Anti-Idiotypic - biosynthesis | Kaplan-Meier Estimate | Adrenal Cortex Hormones - pharmacology | Disease Progression | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Interleukin-6 - immunology | Aged | Pyrazines - pharmacology | Adrenal Cortex Hormones - administration & dosage | Boronic Acids - pharmacology | Medical research | Care and treatment | Relapse | Interleukins | Monoclonal antibodies | Medicine, Experimental | Development and progression | Diseases | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2011, Volume 108, Issue 19, pp. 7914 - 7919
Vaccines can greatly reduce the spread of and deaths from many infectious diseases. However, many infections have no successful vaccines. Better understanding... 
T lymphocytes | Antigens | Influenza A virus | Aluminum | Vaccination | Memory | Antibodies | Infections | Ova | Cellular differentiation | Cross-presentation | MHC tetramer | Toll-like receptor | Cytokine | cytokine | CROSS-REACT | IMMUNITY | VIRUS | MULTIDISCIPLINARY SCIENCES | INFLUENZA | B SURFACE-ANTIGEN | NALP3 INFLAMMASOME | H5N1 | RESPONSES | cross-presentation | INFECTION | LYMPHOCYTES-T | Orthomyxoviridae Infections - prevention & control | Adjuvants, Immunologic - administration & dosage | Ovalbumin - immunology | Serum Albumin, Bovine - administration & dosage | Humans | Lipid A - analogs & derivatives | RNA-Binding Proteins - administration & dosage | Antigen Presentation | Cattle | Female | Influenza A virus - immunology | Apoptosis Regulatory Proteins - biosynthesis | T-Lymphocytes, Cytotoxic - immunology | Lipid A - administration & dosage | Interleukin-6 - genetics | Serum Albumin, Bovine - immunology | RNA-Binding Proteins - immunology | Antigens, Surface - biosynthesis | Mice, Transgenic | Interleukin-6 - deficiency | Mice, Knockout | Animals | Ovalbumin - administration & dosage | Vaccines, Subunit - administration & dosage | Interleukin-6 - biosynthesis | Immunologic Memory | Programmed Cell Death 1 Receptor | Viral Core Proteins - immunology | Mice | Alum Compounds - administration & dosage | Cytokines - biosynthesis | Orthomyxoviridae Infections - immunology | Viral Core Proteins - administration & dosage | Toll-like receptors | Physiological aspects | Immunological adjuvants | Properties | T cells | Molecules | Immunization | Infectious diseases | Rodents | Influenza | T cell receptors | Vaccines | Index Medicus | granzyme B | Immunological memory | Memory cells | Salts | CD8 antigen | Adjuvants | Cytotoxicity | Lymphocytes T | Infection | Interleukin 6 | Influenza A | Differentiation | Monophosphoryl lipid A | Biological Sciences
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2016, Volume 11, Issue 6, pp. e0157956 - e0157956
High-fat diet-induced obesity (DIO) is associated with fatty liver and elevated IL-6 circulating levels. IL-6 administration in rodents has yielded... 
SIGNAL-TRANSDUCTION | SOCS3 | TUMOR-NECROSIS-FACTOR | SUBCUTANEOUS ADIPOSE-TISSUE | INTERLEUKIN-6 CONCENTRATIONS | MULTIDISCIPLINARY SCIENCES | FATTY LIVER | ACTIVATED RECEPTOR-ALPHA | CYTOKINE | HEPATIC STEATOSIS | INSULIN SENSITIVITY | Tumor Necrosis Factor-alpha - metabolism | Carnitine O-Palmitoyltransferase - genetics | Liver - pathology | Liver - enzymology | Fatty Liver - pathology | Diet, High-Fat - adverse effects | Male | Leptin - blood | Carnitine O-Palmitoyltransferase - metabolism | Fatty Acids - metabolism | Interleukin-6 - administration & dosage | STAT3 Transcription Factor - metabolism | Fatty Liver - genetics | Cytokine Receptor gp130 - metabolism | Fatty Liver - blood | Liver - metabolism | Mice, Inbred C57BL | Interleukin-6 - adverse effects | Recombinant Proteins - pharmacology | Down-Regulation - drug effects | Recombinant Proteins - administration & dosage | Rats, Zucker | Up-Regulation - drug effects | Animals | Interleukin-6 - pharmacology | Signal Transduction - drug effects | Models, Biological | Mice, Obese | PPAR alpha - metabolism | Receptors, Leptin - metabolism | Blood Glucose - metabolism | Suppressor of Cytokine Signaling 3 Protein - metabolism | Obesity | Complications and side effects | Fatty liver | Analysis | Risk factors | Interleukin-6 | Animal models | Liver | Lipids | Glucose | Kinases | High fat diet | Interleukin 6 | Signal transduction | Restoration | Rodents | Hepatology | Tumor necrosis factor-TNF | Lipid metabolism | Lipogenesis | Enzymes | Liver diseases | Desensitization | Cytokines | Stat3 protein | Triglycerides | Tumor necrosis factor-α | Metabolism | Gene expression | Fatty acids | Steatosis | Serum levels | Signaling | Diet | Blood circulation | Leptin | Mice | Binding sites | Index Medicus
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 03/2016, Volume 173, Issue 6, pp. 1070 - 1084
Journal Article
Equine Veterinary Journal, ISSN 0425-1644, 11/2018, Volume 50, Issue 6, pp. 733 - 738
Background: In horses castration with primary intention healing is usually performed under balanced inhalation anaesthesia. To optimise analgesia, the use of... 
horse | TNF‐α | analgesia | IL‐6 | TNF-α | IL-6 | TNF-alpha | BUTORPHANOL | INTERLEUKIN-6 | VISCERAL PAIN | RESPONSES | INTRATESTICULAR INJECTION | LIDOCAINE | DOGS | VETERINARY SCIENCES | COMPLICATIONS | SCALE | Clonixin - administration & dosage | Anesthesia - methods | Mepivacaine - administration & dosage | Prospective Studies | Hypnotics and Sedatives - administration & dosage | Male | Horses - physiology | Nociceptive Pain - prevention & control | Ketamine - administration & dosage | Medetomidine - administration & dosage | Arterial Pressure - drug effects | Clonixin - analogs & derivatives | Anesthetics, Local - administration & dosage | Pain, Postoperative - veterinary | Cytokines - blood | Cytokines - metabolism | Double-Blind Method | Diazepam - administration & dosage | Isoflurane - administration & dosage | Analgesics - administration & dosage | Orchiectomy - veterinary | Random Allocation | Dobutamine - administration & dosage | Pain, Postoperative - prevention & control | Animals | Cardiotonic Agents - administration & dosage | Horses - surgery | Anesthesia - veterinary | Anesthesia | Morphine | Care and treatment | Pain | Heart beat | Interleukins | Pain perception | Cytokines | Complications | Interleukin | Data processing | Regression analysis | Variance analysis | Isoflurane | Inhalation | Heart rate | Analgesia | Ketamine | Motivation | Castration | Tumor necrosis factor | Horses | Healing | Respiration | Diazepam | Tumors | Index Medicus | Analytical Clinical Studies
Journal Article