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Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 08/2015, Volume 172, Issue 15, pp. 3805 - 3816
Journal Article
Brain, Behavior, and Immunity, ISSN 0889-1591, 2016, Volume 56, pp. 378 - 389
Highlights • MBP84-104 peptide, injected into an intact nerve, produces long-lasting pain. • IL-6 is the top-induced cytokine by MBP84-104, regardless of T... 
Psychiatry | Allergy and Immunology | Allodynia | Female pain | Gabapentin | Myelin | Adaptive immunity | T cells | Myelin basic protein | Chronic pain | Mechanical hypersensitivity | Neuropathic pain | Interleukin 6 | Cacna2d1 | Nude rat | Autoimmunity and pain | MBP | Interferon | DORSAL-ROOT GANGLIA | IMMUNOLOGY | PERIPHERAL-NERVE INJURY | CONSTRICTION INJURY | MECHANICAL PAIN HYPERSENSITIVITY | SCIATIC-NERVE | GENE-EXPRESSION | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | ALTERED PEPTIDE LIGAND | NEUROSCIENCES | SATELLITE GLIAL-CELLS | Hyperalgesia - chemically induced | Lidocaine - pharmacology | Spinal Cord - metabolism | Genomics | Peptide Fragments - pharmacology | Rats, Nude | Myelin Basic Protein - administration & dosage | Female | Myelin Basic Protein - pharmacology | Sciatic Nerve - drug effects | Interleukin-6 - metabolism | Peptide Fragments - administration & dosage | Rats | gamma-Aminobutyric Acid - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Calcium Channel Blockers - pharmacology | Rats, Sprague-Dawley | Cyclooxygenase Inhibitors - pharmacology | Animals | Hyperalgesia - drug therapy | Cyclohexanecarboxylic Acids - pharmacology | Interleukin-6 - immunology | Voltage-Gated Sodium Channel Blockers - pharmacology | Dizocilpine Maleate - pharmacology | Amines - pharmacology | Ketorolac - pharmacology | Index Medicus
Journal Article
Rheumatology, ISSN 1462-0324, 11/2008, Volume 47, Issue 11, pp. 1635 - 1640
Objectives. We investigated the influence of cytokines on the expression of RANK ligand (RANKL) in fibroblast-like synoviocytes from RA patients (RA-FLS).... 
Interleukin-1 | Soluble IL-6 receptor | Tumour necrosis factor-α | Receptor activator of nuclear factor-αB ligand | Tocilizumab | Janus kinase/signal transducer and activator of transcription | Mitogen-activated protein kinase | Fibroblast-like synoviocytes | Interleukin-17 | Interleukin-6 | RHEUMATOID-ARTHRITIS | ACTIVATION | NECROSIS-FACTOR-ALPHA | CYTOKINE | T-CELL | RHEUMATOLOGY | OSTEOBLASTIC CELLS | Receptor activator of nuclear factor-kappa B ligand | SOLUBLE INTERLEUKIN-6 RECEPTORS | OSTEOPROTEGERIN LIGAND | OSTEOCLAST DIFFERENTIATION | EXPRESSION | Tumour necrosis factor-alpha | Immunohistochemistry | Interleukin-1beta - pharmacology | RANK Ligand - metabolism | Humans | RNA, Messenger - analysis | Receptors, Interleukin-6 - antagonists & inhibitors | Synovial Membrane - drug effects | Interleukin-17 - pharmacology | Antibodies, Monoclonal, Humanized | Arthritis, Rheumatoid - metabolism | Mitogen-Activated Protein Kinase Kinases - metabolism | Reverse Transcriptase Polymerase Chain Reaction - methods | Fibroblasts | Flavonoids - pharmacology | Phosphorylation - drug effects | Receptor Activator of Nuclear Factor-kappa B - metabolism | Interleukin-6 - metabolism | STAT3 Transcription Factor - metabolism | Blotting, Western - methods | Antibodies, Monoclonal - pharmacology | Cells, Cultured | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | RANK Ligand - analysis | Recombinant Proteins - pharmacology | Stimulation, Chemical | Synovial Membrane - metabolism | RANK Ligand - genetics | Tumor Necrosis Factor-alpha - pharmacology | Interleukin-6 - pharmacology | Signal Transduction - physiology | Cell Proliferation - drug effects | Sesquiterpenes - pharmacology | Receptors, Interleukin-6 - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
AIDS, ISSN 0269-9370, 07/2012, Volume 26, Issue 11, pp. 1371 - 1385
Background: The effect of specific antiretrovirals on inflammation is unclear. Methods: A5224s was a substudy of A5202, which randomized HIV-infected... 
endothelial activation markers | abacavir | C-reactive protein | TNF alpha | inflammation markers | interleukin-6 | INTIMA-MEDIA THICKNESS | INFECTIOUS DISEASES | ABACAVIR-LAMIVUDINE | BONE-MINERAL DENSITY | IMMUNOLOGY | HIV-INFECTED PATIENTS | TENOFOVIR-EMTRICITABINE | INDIVIDUAL ANTIRETROVIRAL DRUGS | VIROLOGY | CLINICAL-TRIALS | ACUTE MYOCARDIAL-INFARCTION | Anti-HIV Agents - pharmacology | Humans | Tumor Necrosis Factor-alpha - blood | Deoxycytidine - pharmacology | Male | Inflammation - blood | Tenofovir | Acquired Immunodeficiency Syndrome - immunology | C-Reactive Protein - metabolism | Interleukin-6 - blood | Atazanavir Sulfate | Adult | Female | Ritonavir - pharmacology | C-Reactive Protein - drug effects | Acquired Immunodeficiency Syndrome - blood | Emtricitabine | Dideoxynucleosides - pharmacology | HIV-1 - metabolism | Adenine - analogs & derivatives | Adenine - pharmacology | Inflammation - immunology | Biomarkers - blood | Acquired Immunodeficiency Syndrome - drug therapy | Organophosphonates - pharmacology | Tumor Necrosis Factor-alpha - drug effects | Benzoxazines - pharmacology | Lamivudine - pharmacology | Pyridines - pharmacology | Oligopeptides - pharmacology | Deoxycytidine - analogs & derivatives | Drug Combinations | Antiviral agents | nucleoside reverse transcriptase inhibitors | RNA | Ritonavir | tenofovir | Lamivudine | Inflammation | Efavirenz | CD4 antigen | Cell adhesion molecules | Interleukin 6 | Abacavir | Age | Tumor necrosis factor- alpha | Index Medicus | AIDS/HIV
Journal Article
Diabetes, ISSN 0012-1797, 02/2011, Volume 60, Issue 2, pp. 537 - 547
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2002, Volume 277, Issue 19, pp. 16639 - 16647
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2010, Volume 647, Issue 1, pp. 161 - 170
The antifibrogenic effect of taurine in experimental liver fibrosis has been shown. The role of taurine to abate fibrogenic mediators and collagen deposition... 
Oxidative stress | Taurine | Experimental liver cirrhosis | Iron | Liver fibrosis | Ethanol | LIPID-PEROXIDATION | INJURY | INCREASES | HEPATIC-FIBROSIS | CIRRHOSIS | PHARMACOLOGY & PHARMACY | MICE | CARBON-TETRACHLORIDE | EXPRESSION | Tumor Necrosis Factor-alpha - metabolism | Iron - administration & dosage | Trace Elements - metabolism | Rats, Wistar | Antioxidants - metabolism | Protective Agents - metabolism | Ethanol - administration & dosage | Hepatic Stellate Cells - metabolism | Male | Amino Acids - administration & dosage | Trace Elements - pharmacology | Amino Acids - pharmacology | Liver Cirrhosis - chemically induced | Central Nervous System Depressants - pharmacology | Amino Acids - metabolism | Liver - drug effects | Interleukin-6 - blood | Protective Agents - pharmacology | Liver Cirrhosis - metabolism | Collagen - pharmacology | Iron - pharmacology | Interleukin-6 - metabolism | Trace Elements - administration & dosage | Cytokines - blood | Ethanol - metabolism | Cytokines - metabolism | Liver - metabolism | Rats | Antioxidants - pharmacology | Iron - metabolism | Transforming Growth Factor beta - blood | Collagen - metabolism | Transforming Growth Factor beta - pharmacology | Tumor Necrosis Factor-alpha - pharmacology | Ethanol - pharmacology | Animals | Interleukin-6 - pharmacology | Central Nervous System Depressants - administration & dosage | Liver Cirrhosis - pathology | Liver - cytology | Taurine - administration & dosage | Oxidative Stress - drug effects | Protective Agents - administration & dosage | Taurine - pharmacology | Taurine - metabolism | Transforming Growth Factor beta - metabolism | Cytokines - pharmacology | Central Nervous System Depressants - metabolism | Cell research | Cytokines | Collagen | Liver | Fibrosis | Transforming growth factors | Liver cirrhosis | Index Medicus | Actin
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2012, Volume 287, Issue 4, pp. 2666 - 2677
IL-6 has been shown to play a major role in collagen up-regulation process during cardiac hypertrophy, although the precise mechanism is still not known. In... 
ISCHEMIA/REPERFUSION INJURY | PRESSURE-OVERLOAD | MYOCARDIAL FIBROSIS | JAK-STAT | BIOCHEMISTRY & MOLECULAR BIOLOGY | CARDIAC-HYPERTROPHY | ANGIOTENSIN-II | GROWTH-FACTOR | DILATED CARDIOMYOPATHY | UP-REGULATION | CELL-DEATH | Nitriles - pharmacology | Rats, Wistar | Humans | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Cardiomegaly - pathology | Male | Extracellular Signal-Regulated MAP Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Phosphorylation - genetics | STAT1 Transcription Factor - metabolism | MAP Kinase Signaling System - genetics | Antineoplastic Agents - pharmacology | Collagen - biosynthesis | Collagen - genetics | p38 Mitogen-Activated Protein Kinases - metabolism | Phosphorylation - drug effects | Interleukin-6 - metabolism | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Disease Models, Animal | Fibroblasts - metabolism | Butadienes - pharmacology | Interleukin-6 - genetics | Cells, Cultured | Enzyme Inhibitors - pharmacology | Interleukin-6 - adverse effects | Rats | p38 Mitogen-Activated Protein Kinases - genetics | Imidazoles - pharmacology | Vidarabine - analogs & derivatives | Down-Regulation - drug effects | Fibroblasts - pathology | STAT1 Transcription Factor - genetics | Down-Regulation - genetics | Vidarabine - pharmacology | Animals | MAP Kinase Signaling System - drug effects | Interleukin-6 - pharmacology | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Cardiomegaly - chemically induced | Pyridines - pharmacology | Cardiomegaly - genetics | STAT3 Transcription Factor - antagonists & inhibitors | Cardiomegaly - metabolism | Index Medicus | Interleukin 6 | Molecular Bases of Disease | STAT Transcription Factor | Extracellular Matrix | Collagen | p38 MAPK | Cardiac Hypertrophy
Journal Article
Immunology, ISSN 0019-2805, 07/2010, Volume 130, Issue 3, pp. 399 - 409
Calcitonin gene‐related peptide (CGRP) is widely distributed and plays important roles in a wide array of biological functions. It is enriched in primary... 
cytokine | macrophage | chemokine | enzyme‐linked immunosorbent assay | neuropeptide | Chemokine | Neuropeptide | Enzyme-linked immunosorbent assay | Cytokine | Macrophage | TRIGEMINAL GANGLION | ALVEOLAR EPITHELIAL-CELLS | NECROSIS-FACTOR-ALPHA | ADRENOMEDULLIN RECEPTORS | IMMUNOLOGY | RAT SENSORY NEURONS | HUMAN MONOCYTES | CYTOKINE PRODUCTION | enzyme-linked immunosorbent assay | RECEPTOR-LIKE RECEPTOR | NF-KAPPA-B | ACTIVITY-MODIFYING PROTEIN-1 | Interleukin-6 - antagonists & inhibitors | Nitriles - pharmacology | Receptor, trkA - antagonists & inhibitors | Receptor, trkA - immunology | Intracellular Signaling Peptides and Proteins - immunology | Peptide Fragments - pharmacology | Calcitonin Receptor-Like Protein | Nitrobenzenes - pharmacology | Sulfones - pharmacology | Nerve Growth Factor - antagonists & inhibitors | I-kappa B Proteins - antagonists & inhibitors | Receptors, Calcitonin - antagonists & inhibitors | Antibodies - immunology | Toll-Like Receptor 4 - agonists | Calcitonin Gene-Related Peptide - metabolism | Interleukin-1beta - antagonists & inhibitors | Cell Line | Dinoprostone - pharmacology | Cyclooxygenase 2 Inhibitors - pharmacology | Cytokines - metabolism | Calcitonin Gene-Related Peptide - pharmacology | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Interleukin-1beta - immunology | Membrane Proteins - immunology | Sulfonamides - pharmacology | Piperazines - pharmacology | Cycloheximide - pharmacology | Antibodies - pharmacology | Macrophages - metabolism | Animals | Receptors, Calcitonin - immunology | Membrane Proteins - antagonists & inhibitors | Interleukin-6 - immunology | Lipopolysaccharides - pharmacology | Macrophages - drug effects | Receptor Activity-Modifying Proteins | Chemokines - metabolism | Mice | Kinetics | Quinazolines - pharmacology | Dactinomycin - pharmacology | Peptides | Immunotherapy | Prostaglandins E | Nerve growth factor | Inflammation | Macrophages | Mitogens | Cytokines | Rodents | Immune system | Index Medicus | Original
Journal Article
Cancer Cell, ISSN 1535-6108, 2006, Volume 10, Issue 4, pp. 309 - 319
Journal Article